Made available in DSpace on 2014-12-17T15:16:13Z (GMT). No. of bitstreams: 1 AngeloAPN_DISSERT.pdf: 995336 bytes, checksum: 4255a44d807a847caa19fe61283e58b9 (MD5) Previous issue date: 2011-04-15 / Background: Obesity may affect the respiratory system, causing changes in respiratory function and in the pulmonary volumes and flows. Objectives: To evaluate the influence of obesity in the movement of thoracoabdominal complex at rest and during maximal voluntary ventilation (MVV), and the contribution between the different compartments of this complex and the volume changes of chest wall between obese and non-obese patients. Materials and Methods: We studied 16 patients divided into two groups: the obese group (n = 8) and group non-obese (n = 8). The two groups were homogeneous in terms of spirometric characteristics (FVC mean: 4.97 ? 0.6 L - 92.91 ? 10.17% predicted, and 4.52 ? 0.6 L - 93.59 ? 8.05%), age 25.6 ? 5.0 and 26.8 ? 4.9 years, in non-obese and obese respectively. BMI was 24.93 ? 3.0 and 39.18 ? 4.3 kg/m2 in the groups investigated. All subjects performed breathing calm and slow and maneuver MVV, during registration for optoelectronic plethysmography. Statistical analysis: we used the unpaired t test and Mann-Whitney. Results: Obese individuals had a lower percentage contribution of the rib cage abdominal (RCa) during breathing at rest and VVM. The variation of end expiratory (EELV) and end inspiratory (EILV) lung volumes were lower in obese subjects. It has been found asynchrony and higher distortion between compartments of thoracoabdominal complex in obese subjects when compared to non-obese. Conclusions: Central obesity impairs the ventilation lung, reducing to adaptation efforts and increasing the ventilatory work / Contextualiza??o: A obesidade pode afetar o sistema respirat?rio, causando altera??es na mec?nica ventilat?ria, nos volumes e fluxos pulmonares. Objetivos: Avaliar a influ?ncia da obesidade no movimento do complexo t?raco-abdominal durante o repouso e durante a ventila??o volunt?ria m?xima (VVM), assim como a contribui??o entre os diferentes compartimentos desse complexo e as varia??es de volume da parede tor?cica e entre obesos e n?o obesos. Materiais e M?todos: Foram avaliados 16 indiv?duos divididos em dois grupos: grupo de obesos (n = 8) e grupo de eutr?ficos (n = 8). Os dois grupos foram homog?neos quanto ?s caracter?sticas espirom?tricas (m?dia de CVF: 4,97 ? 0,6 L 92,91 ? 10,17 % do predito, e 4,52 ? 0,6 L 93,59 ? 8,05 %), idade 25,6 ? 5,0 e 26,8 ? 4,9 anos, em eutr?ficos e obesos respectivamente. O IMC foi de 24,93 ? 3,0 e 39,18 ? 4,3 kg/m2, nos grupos investigados. Todos os sujeitos realizaram respira??o calma e lenta e a manobra de Ventila??o volunt?ria m?xima, durante o registro por pletismografia optoeletr?nica. Para an?lise estat?stica, foram utilizados os testes t n?o pareado e de Mann-Whitney. Resultados: Os indiv?duos obesos apresentaram menor contribui??o percentual da caixa tor?cica abdominal (RCa) durante a respira??o em repouso e na VVM. A varia??o dos volumes pulmonares expirat?rio (VEE) e inspirat?rio finais (VEI) foram menores nos sujeitos obesos. Foram constatados maiores assincronia e distor??o entre os compartimentos do complexo t?raco-abdominal nos obesos, quando comparados aos eutr?ficos. Conclus?es: A obesidade central interfere negativamente na ventila??o pulmonar, reduzindo a adapta??o aos esfor?os e incrementando o trabalho ventilat?rio