This study examined hospital governance in British Columbia. Considered to be one of the most important issues facing the health care industry today, hospital governance is nevertheless an ill-defined and poorly understood concept. Foundational and exploratory in nature, the study’s primary objectives were: a) to define hospital governance within the context of British Columbia; b) to examine the structural and functional relationships among key participants; c) to investigate decision-making responsibilities; d) to investigate what, if any, variations exist in the governance of acute care, long term care, and specialized care hospitals; and e) to explore the critical issues which face hospital governance today and in the future under New Directions policy initiatives. All hospitals (N=107) in the province were studied, with the exception of diagnostic treatment centers, private for-profit facilities, military, and federal institutions. Utilizing documentary examination, survey administration, and interview techniques, the study included hospital chief executive officers (N=106), hospital board members (N=735), hospital board chairs (N=106), and selected high ranking senior officials from the Ministry of Health who had direct responsibility for hospital activities (N=15). Results of the study provide for in-depth demographic board profiles, and show that hospital governance is similarly defined across all hospital categories as “a complex relationship of overlapping structures and activities which has the responsibility and the authority to oversee the organization’s operation and to ensure its commitment of providing optimum health care to its residents.” The study identifies the key participants of hospital governance and delineates sixteen activities considered to be under the hospital board’s domain. Seven issues are identified as being critical for hospital governance in the future. Although there was general agreement as to the individuals most often responsible for recommending and implementing activities brought before the board, there were considerable perceptual differences between participants as to who possesses final decision-making responsibility. Data results consistently demonstrated important differences in responses between the hospital and Ministry populations. The study shows that overall, the participants of hospital governance are generally satisfied with the traditional roles and structures of hospital boards and are overwhelmingly dissatisfied with New Directions policy initiatives. This study further suggests that due to the discrepancies in priorities, perceptions, and ideologies of the hospital and Ministry populations, hospital governance is in a highly volatile and transitive state. / Graduate and Postdoctoral Studies / Graduate

M.Comm. / Health care in South Africa has been well described in terms of structure. However, to what extent would it be possible to describe the health care sector in South Africa in terms of that used to describe an industry? What conclusions could be drawn at the end of the study if this was or was not possible? Strong emphasis in industry analysis is placed on the nature of the competitive forces and on levels of profitability. Can the South African health care sector also be described in those terms? The following objectives can be identified in this study: To complete a literature review on the structure of health care in South Africa in terms of facilities, geographic location, services offered, manpower, financing, remuneration, population served and legislation. To complete a literature review on models and methods that can be used to analyse industries. To determine to what extent it is possible to apply Porter's model (and others) of industry analysis to the South African health care industry. To identify key success factors for the industry. To draw conclusions from the study and make some recommendations.

Preventing healthcare-associated infections (HAI) is a national priority. The Centers for Disease Control and Prevention estimates that one of every 25 hospitalized patients contract a HAI while receiving care. In 2009, the annual cost for HAIs in United States’ hospitals was estimated to be $40 billion, and there were 99,000 HAI-associated deaths. In nursing homes (NH), the situation is more dire; among the 4 million NH residents each year, there are 1-2.6 million serious infections and 1 out of every 3 NH residents is colonized with a multi-drug resistant organism. In addition to the frequent infections, over prescription of antibiotics in NH is significant, and frequently inappropriate. NH residents with HAIs are subjected to burdensome treatments and diagnostic procedures, leading to more complications in an already vulnerable population in which quality of life not life prolongation is often the treatment goal. Policy levers are actions designed to realize health objectives that can be taken by either public or private entities, and by individuals or groups. Health policy levers are deployed at all levels including federal, state, regional, and local levels. Vaccinations, such as polio, are one of the great success stories of how policy levers can prevent infections. However, undermined and eroded policy levers can have negative public health consequences, such as seen with the 2018-2019 rash of measles outbreaks. There is much work left to be done improving quality related to infections across all care settings. For this dissertation, I utilized the three-paper format and conducted studies examining the effectiveness of health policy levers used to improve healthcare quality and prevent infections across care settings. These studies were: 1) a systematic review of the published evidence on state mandatory reporting of HAI in hospitals; 2) an environmental scan cataloging state supported initiatives in NH infection prevention, and; 3) a quantitative analysis on the effect of new federal NH regulations on NH quality and patient outcomes. In the systematic review, I found that mandatory reporting was associated with reduced central line associate bloodstream infection rates. The environmental scan demonstrated that wide variation existed between states’ initiatives to support infection prevention in NH. In the quantitative analysis, I found that new federal regulations were significantly associated in improved NH quality in UTI rates and vaccination rates for influenza and pneumonia infections. Based on these results, clinical providers, administrators, policy makers and researchers can use health policy levers to reduce infections and improve quality.

This study explores the effects of income, insurance, and source of medical care on access to and utilization of health services. Profiles of dental, physician, and hospital services use are developed for more than 3,500 Oregonians. Low income, lack of health insurance, and/or an inappropriate source of medical care are hypothesized to be barriers to access and utilization. Households which face one or more of these barriers are identified as falling into a "Health Policy Gap." The data for this study were drawn from a 1978 random telephone survey of 1249 Oregon households. The survey was commissioned by the State Health Planning and Development Agency in conjunction with the Northwest Oregon Health Systems Agency, the Western Oregon Health Systems Agency, and the Eastern Oregon Health Systems Agency. The questionnaire was developed by the Oregon State University Research Center. Information was collected on use of health services, insurance coverage, income, household structure, health needs, health behaviors, and health satisfaction. A behavioral model of health services utilization was constructed, dividing the independent variables according to their relative mutability or amenity to policy intervention. Income, insurance, and source of care were selected as policy variables, while other variables less under policymakers' control were labelled household characteristics. The latter were assumed to reflect a household's propensity to consume services. They included household structure, health need, residential mobility, and health behaviors. Dependent variables included measures of dental and physician visits, use of the telephone for physician advice, preventive exams, and hospitalization during the past year. Multiple techniques of analysis were employed. Cross-tabular procedures were applied to investigate the interrelationship of income, insurance, and source of care. Multiple linear regression and partial correlation methods were used to select as control variables household characteristics highly correlated to each measure of health services use. Analysis of variance and multiple classification analysis were used to develop profiles of health services use. These last techniques allowed an examination of the relationship of each policy variable and health measure while applying increasing levels of statistical control. The initial bivariate relationship was studied in isolation; it was then studied while controlling for the other policy variables, and finally while controlling for both the other policy variables as well as selected household characteristic variables. Findings support the hypotheses. Income is found to be related to insurance coverage, and insurance coverage to source of medical care, although income is not found to be directly related to source of care. Low income, lack of insurance, and an inappropriate source of medical care depress use across almost all services. However, their relative barrier effects differ by the measure of service examined. After controlling for the effects of household structure, health need, residential mobility, and health behaviors, the greatest disparity in use of dental services remains due to income, in physician services to insurance and income, and in hospital services to insurance. Clear implications arise for policymakers, whether in the public or private sectors. The low income, the uninsured, and those with an inappropriate source of care face real barriers to access. Since the relative magnitude of these barrier effects vary by the health measure examined, neither income, insurance, nor health system delivery strategies can be assumed to evenly enhance use patterns. Their effects must be separately estimated for differing measures of health services. Furthermore, the relationship between these policy variables needs detailed study before large-scale policy interventions are undertaken. Understanding the complexity of these findings for different measures of health services as well as the interrelationship of income, health insurance, and source of care is crucial in designing and implementing more effective and equitable health policies in the future.

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This dissertation discusses the political dimensions of scientific practice in Taiwan from two perspectives: the social contingencies of scientific knowledge and the role of government in medical science. The history of Taiwanese hepatitis B control program from 1980 to 1993 provides a valuable case study to investigate these issues. The controversies over the safety of the hepatitis B plasma vaccine display the social contingency of scientific knowledge. On the basis of different concerns or political interests, numerous participants joined the scientists in interactively shaping and reshaping the vaccine safety. When participants used various strategies and contradictory scientific knowledge to argue against each other, the credibility of experts and their scientific knowledge was downgraded, which in tum prevented scientific knowledge from serving as the sole arbitrator of resolving the controversies. The socially contingent characteristics of scientific knowledge provided a space for government agencies participating in shaping scientific knowledge formation. This historical case displays how the Taiwanese government significantly influenced the scientific knowledge formation regarding hepatitis B control in Taiwan. The government designed science policy to promote hepatitis B control, and government officials were involved in resolving the controversies over the safety of the hepatitis B plasma vaccine. Government scientists not only gave government agencies a certain degree of interpretative authority in the controversies, but also produced alternative scientific knowledge to support the government's science policy. When the government policy changed in response to social problems, the scientific knowledge regarding hepatitis B control also changed. This dissertation concludes by calling for more attention toward studying the role of government in scientific practice. Without considering how the Taiwanese government participated in the hepatitis B control program, our understanding about the formation and change of scientific knowledge regarding hepatitis B control would be incomplete. / Ph. D.

The original publication is available at http:/www.plosone.org / Introduction: The utility of T-cell based interferon-gamma release assays for the diagnosis of latent tuberculosis infection remains unclear in settings with a high burden of tuberculosis. Objectives: To determine risk factors associated with positive QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) results and the level of agreement between the tests; to explore the hypotheses that positivity in QFT-GIT is more related to recent infection and less affected by HIV than the TST. Methods: Adult household contacts of tuberculosis patients were invited to participate in a cross-sectional study across 24 communities in Zambia and South Africa. HIV, QFT-GIT and TST tests were done. A questionnaire was used to assess risk factors. Results: A total of 2,220 contacts were seen. 1,803 individuals had interpretable results for both tests, 1,147 (63.6%) were QFT-GIT positive while 725 (40.2%) were TST positive. Agreement between the tests was low (kappa = 0.24). QFT-GIT and TST results were associated with increasing age (adjusted OR [aOR] for each 10 year increase for QFT-GIT 1.15; 95% CI: 1.06-1.25, and for TST aOR: 1.10; 95% CI 1.01-1.20). HIV positivity was less common among those with positive results on QFT-GIT (aOR: 0.51; 95% CI: 0.39-0.67) and TST (aOR: 0.61; 95% CI: 0.46-0.82). Smear positivity of the index case was associated with QFT-GIT (aOR: 1.25; 95% CI: 0.90-1.74) and TST (aOR: 1.39; 95% CI: 0.98-1.98) results. We found little evidence in our data to support our hypotheses. Conclusion: QFT-GIT may not be more sensitive than the TST to detect risk factors associated with tuberculous infection. We found little evidence to support the hypotheses that positivity in QFT-GIT is more related to recent infection and less affected by HIV than the TST. © 2011 Shanaube et al. / Publishers' Version

In 1993, a group of unionized bedside nurses took control of their state nursing association. In 1995, they disenfranchised themselves from the American Nurses Association, which historically had billed itself as - THE voice of the profession of nursing. This study utilizes a case study format to look at who they are, what their intentions are, and what their vision is for the future of the profession. Twenty questions were submitted to key participants identified by the California Nurses Association (CNA). The questions were organized into three main areas: the period leading up to the disenfranchisement, the period of growth after the takeover up until the historic passage of the ratio laws and whistle blower protection, and the period after the passage of the laws wherein the association began a national movement. This movement continues to evolve, and in December, 2009, the CNA (now the National Nurses United) became the largest nursing organization in the country. As the title of the study implies, one intention of the study is to look at the implications for the profession of nursing and the inevitable political implications for the national healthcare debate. Another purpose is to introduce this group to the academic and professional nursing communities, which until now have largely ignored them. Still another purpose is to lay out a blueprint for other state nursing associations who may wish to empower themselves, to analyze the process by which this group has grown to political prominence. No other nursing association has been able to duplicate their political success. Finally, the study raises many crucial questions which nursing academics and nursing leaders must address if nursing is going to able to utilize our only real political power, the power of numbers. Uniting the field, or at least growing the association to significant numerical strength, is the only way nursing can become an equal partner in the national healthcare debate. / by John Silver. / Thesis (Ph.D.)--Florida Atlantic University, 2010 / Includes bibliography. / Electronic reproduction. Boca Raton, Fla., 2010. Mode of access: World Wide Web.

Luo, Weixiang. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2013. / Includes bibliographical references (leaves 90-105). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts also in Chinese.