Stereo types and stigmas of individuals with mental illnesses have proved to be a major roadblock preventing these individuals from seeking help. The news media, despite having a responsibility to accurately inform the public, has played a significant role in portraying individuals with mental illness as violent, unpredictable, dangerous, and unfit to live with the rest of “normal” society. This happens through the words journalists choose to use and the information they choose in included, and excluded, when reporting on mental health issues. This study attempts to establish a guideline that journalists can follow that will hopefully reduce the stigma of mental illness in the media, and eventually in society. This study used a 2 x 2 ANCOVA to test two independent variables (amount of labeling terms and amount of corrective information). The variables were manipulated by modifying a news article four times to produce articles with varying levels of labeling terms and corrective information. A control article was also be used. The articles were randomized and passed out to 220 undergraduate college students at the University of North Texas who completed a questionnaire, read their assigned article, and then completed a second questionnaire to determine the impact the article had on their attitudes about individuals with mental illnesses.

Thesis (M.A. (Clinical Psychology)) -- University of Limpopo, 2018 / Extensive research on the knowledge and attitudes of students regarding mental illness has been conducted among university students globally. Some of these studies have indicated that students’ attitudes are influenced by a number of factors such as gender, year of study and contact with people with mental illness. In addition, university students’ attitudes towards people with mental illness were found to vary based on the course that they were enrolled in. The present study sought to explore the knowledge and attitudes of university postgraduate students towards mental illness. A survey research design was adopted. Using systematic random sampling, 143 students enrolled for an honours degree in the Faculty of Humanities at the University of Limpopo were selected and enlisted to participate in the study. The students completed a self-reported questionnaire including the Mental Health Knowledge Schedule (MAKS) and Attitude Scale for Mental Illness (ASMI). The results of the study indicate that nearly half of students (49.7%) have adequate knowledge about mental illness. Most students (mean = 38.55) were able to identify mental disorders and were familiar with various treatment modalities. Gender, study course, and previous contact with people with mental illness had no effect on the students’ knowledge of mental illness. A further exploration revealed that 50.3% of the students displayed favourable attitudes towards people with mental illness. 31.5% of the students reported having previous contact with people with mental illness. A majority (60%) of students who had previous contact with someone with mental illness displayed favourable attitudes compared to students (46%) with no previous contact. Lastly, there was no relationship between the students’ knowledge about mental illnesses and their attitudes. The results suggest that educational and awareness campaigns aimed at improving students’ knowledge about mental illness and attitudes should promote contact with the mentally ill. However, the contact should be the type that will cultivate positive attitudes.

Thesis (MPH.) -- University of Limpopo, 2019 / Background- care of the mentally ill by family members is done with little or no supervision by skilled health workers. Therefore, the purpose of the study was to investigate the experiences of family members of patients living with mental illness in the Capricorn District of Limpopo Province in South Africa. Objective- to explore and describe the experiences of family members caring for patients living with mental illness. Methods- A qualitative, descriptive and exploratory design was used. Non-probability sampling of the purposive and convenient type was used to explore and describe the experiences of family members of patients living with mental illness in the Capricorn District. Data were collected from fifteen family members caring for MHCUs, by using open-ended semi-structured face-to-face interviews. Data were audio recorded and observations were done during interviews. Trustworthiness was ensured by applying credibility, transferability, confirmability and dependability. Data were analysed using Tech’s open-coding method. Results- family members experience disruptive behaviour from MHCUs and they also have to adapt to new routines that are at times unfavourable. As a result, the family members’ health and quality of life are affected, thus making them susceptible to having mental illness and other medical conditions as well. Conclusion- There is a need for family members caring for persons living with mental illness to be given emotional and social support. community projects such as support groups for family members caring for MHCUs and goal directed standard operations procedures at the Psychiatric Ward – specifically designed and implemented for family members caring for MHCUs, are recommended.

No description available.

Thesis (Ph.D. (Psychology)) -- University of Limpopo, 2016 / After the World Health Organization (WHO) declared 2010 a decade of indigenous knowledge systems, there has been an increase in the studies on the role of African traditional healers in describing mental illness and its treatment. Studies have pointed to the relevance of traditional healing in primary health care in many developing countries. The aim of the present study was to explore the conceptualisation and treatment of mental illness by Zezuru Shona traditional healers in Goromonzi District in Zimbabwe. A qualitative research design, and in particular, the phenomenological method was used in the present study. Ten Shona traditional healers were selected through purposive and snowball sampling and requested to participate in the study. Data was collected through in-depth interviews and analysed using Hycner’s phenomenological explicitation process. Five major themes related to the traiditonal healers’ conceptualisation on mental illness were identified. These are: a). Types/characteristics of mental illness; b). Causes of mental illness; c). Diagnosis and treatment of mental illness; d). Challenges faced by traditional healers; and, e). Facilitating factors in the work of traditional healers. The study further revealed that there are a number of illnesses that are are not mental illness but could be closely associated with mental illness. These are epilepsy (pfari), locking (kusungwa) and sexual dysfunctions. Culture was found to play a central role in the traditional healers’ conceptualisation and treatment of mental illness. In this regard, spirituality was found to be a critical factor in the work of traditional healers in diagnosing, interpreting, treating and preventing mental illness and the associated conditions of ill health. These results were discussed in the context of indigenous knowledge systems and mental illness. The study is concluded by recommending the need to have a holistic understanding of mental illness and associated conditions.

G-protein coupled receptor 50 (GPR50) is a genetic risk factor for psychiatric illness. It is a member of the melatonin receptor family, which includes the well characterised melatonin receptors 1 and 2 (MT1 and MT2). However, the ligand for GPR50 remains elusive and little is known about GPR50 signalling pathways. Despite this, GPR50 is known to enhance neurite outgrowth and inhibit the actions of the neurite outgrowth inhibitor NOGO-A. Existing evidence also indicates a role in lipid metabolism; GPR50 knockout mice displayed abnormalities in energy homeostasis and weight control, whilst sequence variants are associated with altered lipid levels in humans. Further, a yeast-2-hybrid screen identified SREBF2 and ABCA2, regulators of lipid homeostasis, as GPR50 interactors. This thesis explores the role of GPR50 in neuronal development and lipid metabolism. The work presented in this thesis shows that GPR50 promotes neuronal differentiation. Overexpression significantly increased the number of neurites per cell in SH-SY5Y cells. Further, dendritic branching was enhanced by GPR50 transfection in hippocampal and cortical neurons (DIV 14). In hippocampal neurons, GPR50 transfection also lead to a shift towards spine maturity although it had no effect on spine morphology, suggesting GPR50 enhances spine development but may not alter synaptic strength. The effect of GPR50 on neuronal morphology may be driven by actin remodelling. Immunocytochemistry showed an enrichment of GPR50 in highly dynamic regions of the membrane, i.e. the lamellipodia and dendritic spines. Overexpression in SH-SY5Y cells also resulted in an increase in WAVE-2 and phosphorylated RAC1/CDC42, key modulators of actin dynamics. Additionally, GPR50 transfection altered the protein level and localisation of α- catenin, another regulator of actin organisation, in HEK293 and SH-SY5Y cells respectively. An involvement of GPR50 in lipid metabolism has also been demonstrated in this thesis. Verification of the Y2H study suggested GPR50 does not physically interact with SREBF2 or ABCA2. However, ABCA2 appears to induce the intracellular localisation of GPR50 in several cell lines. In SH-SY5Y cells, this was mimicked by the inhibition of cholesterol trafficking, suggesting the translocation of GPR50 to the plasma membrane is dependent on cholesterol transport. Further, the depletion of lipoproteins resulted in the downregulation of GPR50, indicating a responsiveness to lipid levels. Finally, GPR50 increased lipid metabolism, as seen by a decrease in intracellular lipid droplets upon GPR50 overexpression. The data presented here extends previous work indicating a role of GPR50 in neurodevelopment. It also highlights a potential mechanism by which GPR50 regulates neuronal morphology, i.e. via actin remodelling. Reports that GPR50 is involved in energy homeostasis is also supported in this thesis, further, results presented here suggest GPR50 is specifically involved in lipid metabolism. These processes are often disrupted in mental illness, thus this work may provide a functional link between GPR50 and psychiatric disorders.

Traditional understandings of violence by the mentally disordered largely look to mental illness to explain such behaviour. More recently, research has begun to examine the role of alternative factors in driving violent offending in this context. Masculinity is one such factor to which little consideration has thus far been given, in spite of a wealth of literature which associates the construction and maintenance of a masculine identity with violence in the non-mentally disordered context. This thesis proceeds from these current understandings, and examines the nature of the relationship between mental illness, masculinity and violent behaviour. In order to examine this issue, interviews were conducted with a group of 10 male patients diagnosed with major mental illness and with violent offending histories, in a medium secure forensic psychiatric hospital in Scotland. A group of 10 male prisoners serving life sentences in a Scottish adult male prison following convictions for homicide offences were also interviewed, and acted as a comparator group. Following an analysis of these interviews, findings emerged in relation to three key areas of patients’ and prisoners’ accounts: past experiences of violent offending, present experiences of institutional settings, and future hopes for recovery and desistance. In particular, significant similarities and divergences in the experiences of the two groups were apparent, and this thesis advances two key arguments in light of this. Considering first the similarities in patients’ and prisoners’ experiences, it is posited here that for both the mentally ill and non-mentally ill male population the task of constructing and maintaining a masculine identity is a particularly pervasive force in their life histories. It will be demonstrated that for patients and prisoners in this study, masculinity plays a significant role in past violent offending, as well as having important implications for adaptation to present institutional settings, and the creation of a recovered and desisting identity for the future. Second, in looking to the divergences in patients’ and prisoners’ accounts, it is asserted that where major mental illness is present it serves to intercede in these three areas of men’s lives. Extracts from interviews with male patients will illustrate the interceding role of mental illness in violent scenarios from their pasts. In addition, it will be demonstrated that patients’ and prisoners’ respective present situations in institutional settings vary, as diagnosis of mental illness leads patients to be placed in a secure hospital rather than the prison, and the differing nature of these environments results in divergences in adaptation to these settings. Finally, in relation to the future, while prisoners focussed on their hopes for desistance from offending, the diagnosis of mental illness led patients to place recovery from such disorders as the primary process at this point.

For years research has demonstrated a varying incidence of medical disorders manifesting with psychiatric symptoms. A relatively conservative estimate of such so called "medical masquerades" is around 10%. It is important to ascertain whether health care professionals are aware of possible medical masquerades perhaps most especially in a mental health center outpatient setting where non-medically trained clinicians are the first line therapists for treatment in the majority of cases. This study set about to find out how aware three types of health care clinicians (psychiatrists, nonpsychiatrically trained medical doctors, and non-medically trained mental health psychotherapists) are of the prevalence of medical masquerades, and whether these three types of clinicians perform differently on three types of clinical vignettes (psychiatric, somatoform, and medical masquerades). Results revealed that all health care professionals surveyed are aware that there are a percentage of medical masquerades in the clinical population. Results also revealed that the three types of clinicians performed differently on the case vignettes.

No description available.

No description available.