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I provided an updated, comprehensive review of treatments for mothers diagnosed with postpartum depression. Studies included in this meta-analysis were single-group pre-posttest, non-randomized and randomized controlled studies published from 1986 to 2010 that included face-to-face psychotherapy and psychopharmacology as well as non-traditional methods such as exercise and nurse-assisted counseling. 53 published studies were analyzed. The randomized studies showed a moderate to large effects (d= 0.72 to 1.25, k= 9) when postpartum interventions were compared to a control condition, and smaller effects (d= 0.3 to 0.57, k = 13) to treatment as usual. When postpartum interventions were compared to each other there was small to no difference in effect sizes (k = 9). All of the non-randomized comparisons showed no significant difference, except when therapy was compared to treatment as usual (d= 0.55, k = 2). Pre-post studies showed large effect sizes for therapy (d= 0.95, k = 7) and medication treatments (d= 4.30, k = 5). Influence analyses suggest that two studies had a large effect on aggregate effect sizes and heterogeneity statistics. Moderator and multivariate analyses were largely underpowered. Publication bias was not significantly related to outcome. Clinical implications for postpartum depression treatments and directions for future research were identified.

The scholarly study of materialism is becoming more common in a variety of disciplines. This thesis provides an empirical review of this burgeoning body of literature by conducting a meta-analysis of the relationship between materialism and psychological well-being. A weighted overall effect size from 47 published and unpublished samples indicated that materialism was significantly related to lower psychological well-being. This effect size was modest in strength (r = .159). Materialism scale, psychological scale valance, age of sample, and publication status of the study did not moderate this relationship. Culture did moderate the relationship, with a stronger relationship in individualistic cultures than in collectivist cultures. Implications for individuals, professionals, and organizations are discussed, and critiques of the extant literature, as well as suggestions for future research, are offered.

Researchers studying the long-term cognitive sequelae of mild traumatic brain injury (mTBI) have produced disparate results. Some studies have shown little to no long-term cognitive effects while others have shown that persistent cognitive sequelae continue to affect a subgroup of patients. Meta-analysis has been used to try to integrate these contrasting results to foster a coherent understanding of the cognitive outcomes following mTBI. However, previous meta-analyses of long-term cognitive sequelae have used studies from a period of mTBI research where methodological rigor has been called into question (Carroll, Cassidy, Holm, Kraus, & Coronado, 2004). Using studies from this period, meta-analysts found little to no effect for long-term cognitive sequelae after mTBI: g = 0.07, d = 0.12 (Binder, Rohling, & Larrabee, 1997), g = 0.11(Frencham, Fox, & Mayberry, 2005), and d = -0.07 (Rohling et al., 2011). The present meta-analysis was conducted to address problems with methodological rigor in the studies used in these previous meta-analyses and address differences in meta-analytic methodology (Pertab, James, & Bigler, 2009). Studies published between January 2003 and August 2010 were rated using the 4-tiered American Academy Neurology (AAN) guidelines for methodological rigor to ensure homogeneity and the methodological rigor of included studies. Seven studies were identified that met criteria for a rating of I or II and five met criteria for the lower ratings of III or IV. When studies of all ratings were combined, a significant effect of g = 0.45 was observed. When only studies rated I and II were combined, a significant effect of g = 0.52 was observed while a significant effect of g = 0.38 was observed when only studies rated III and IV were combined. These effect sizes for long-term cognitive sequelae are much larger than those found in previous meta-analyses. Based on these results, it is likely that methodological rigor and/or heterogeneity amongst included studies can impact meta-analytic effect sizes associated with long-term cognitive sequelae following mTBI. However, analyses did not show that more rigorous studies (i.e., those rated I or II) had significantly higher effect sizes than less rigorous studies (i.e., those rated III or IV), t(10) = .636, p = .845. This non-significant finding may be a result of the analysis being underpowered given the small k. Significant effects for neuropsychological domain were also observed and are reported. Additionally, a conceptual critique of mTBI is made with recommendations for future development of the rating system that Cappa, Conger, and Conger (2011) have put forth for objectively rating the methodological rigor of neuropsychological studies. Concerns are addressed related to the mTBI literature in the areas of mTBI definition, definition of cognitive impairment, problems with the constructs of post-concussion syndrome (PCS) and persistent post-concussion symptoms (PPCS), heterogeneity of outcome measurement, and unaccounted for variables.

Indiana University-Purdue University Indianapolis (IUPUI) / Rising economic inequality has become a widespread trend and concern in recent decades. Economic inequality is often associated with pernicious consequences such as a decrease in individual health and social cohesion and an increase in political conflicts. Does economic inequality have a negative association with prosocial behavior, like many other aspects of inequality? To answer this question, this dissertation investigates the relationship between economic inequality and prosocial behavior, particularly charitable giving, by conducting three empirical studies. The first study is a meta-analysis on the overall relationship between economic inequality and prosocial behavior. Results from 192 effect sizes in 100 studies show that there is a general small, negative relationship between economic inequality and different forms of prosocial behavior. Moderator tests demonstrate that social context, the operationalization of prosocial behavior, the operationalization of economic inequality, and average age of participants significantly moderate the relationship between economic inequality and prosocial behavior. The second study differentiates between redistributive and non-redistributive charitable causes and examines how income inequality is associated with charitable giving to these two causes in China. Using synthesized data from the China Labor-force Dynamics Survey (CLDS) and official data, this study shows that income inequality has no significant relationship with charitable giving to redistributive causes, but it has a negative association with charitable giving to non-redistributive causes. Of the four moderators, only education significantly moderates the relationship between income inequality and redistributive giving. The third study tests whether and how government social spending mediates the relationship between income inequality and charitable giving. Using the US county level panel data, this study finds there is no significant relationship between income inequality and government social spending as well as between government social spending and charitable giving. Thus, government social spending does not significantly mediate the relationship between income inequality and charitable giving. However, income inequality has a robustly and significantly negative relationship with charitable giving. In sum, this dissertation furthers our understanding of the relationship between economic inequality and prosocial behavior, especially charitable giving. Given the higher economic inequality facing many countries, it is a timely dissertation and has important practical implications.

While a wealth of research has deemed cohesion critical for team effectiveness (e.g., Mullen and Copper, 1994; Beal, et al., 2003), less emphasis has been placed on understanding how to get it. Multiple studies do examine cohesion antecedents, but these studies have not yet been integrated in either theoretical or empirical manners. The purpose of this study was thus to begin addressing this gap in the literature. I conducted a series of meta-analyses to identify and explore various antecedents of cohesion, as well as moderators of antecedent-cohesion relationships. Findings revealed a variety of cohesion antecedents. Specifically, team behaviors, emergent states, team composition variables, leadership variables, team interventions, and situational variables, as well as specific variables within each of these categories, were all explored as cohesion antecedents. In most cases, significant relationships with cohesion were demonstrated, and did not differ across levels of analysis or based on cohesion type (i.e., task cohesion, social cohesion, group pride). Hypotheses pertaining to moderators of antecedent-cohesion relationships (e.g., theoretical match between antecedent and cohesion) generally were not supported. Thus, while most antecedents appeared to be important for cohesion's formation and sustainment, some interesting differences emerged, providing insight as to where attention should be focused when enhanced cohesion is desired. Results provide a foundation for the development of more comprehensive models of team cohesion, as well as insight into the mechanisms through which cohesion can be facilitated in practice. Ultimately, findings suggest that teams can become cohesive through the presence of various processes and emergent states, team interventions, and components of their situational context.

Hantavirus is a dangerous zoonotic viral pathogen that is found across Asia, Europe, and the Americas. This virus causes a range of symptoms from flu-like malaise to heart failure and death. It is normally transmitted to humans via the aerosolized feces or urine of infected rodents. Currently, there are no known treatments for the disease, and it continues to threaten human health in endemic areas. In order to identify possible future therapeutic targets, we ran a meta-analysis of existing transcriptomic data collected from infected human tissue. Several genes and cellular pathways were identified, in addition to several potential therapeutics that warrant additional testing as potential future therapeutics for hantavirus infection. Such genes include, but are not limited to SLC27A3, NOG, AMIGO1, NUSAP1, and CDC25C which have not been previously associated with hantavirus infection. In addition, we identified that RIG-I and MDA5-associated anti-viral response genes are downregulated, while downstream elements of these pathways are upregulated, indicative of immune activation via alternate pathways. Finally, among the potential therapeutics we identified are dinaciclib, alvodicib, and ruxolitinib, which limit cellular replication, as well as ruxolitinib, baricitinib, and tofacitinib, which target other human intracellular pathways that may aid in successful viral infection. Crohn's disease is an autoimmune disorder that affects the digestive system of more than six million people worldwide, with most cases found in North America and Europe. Although the disease can occur throughout the entire digestive tract, the classical sign of disease progression is inflammation of the intestine. There are a number of factors that have been associated with the onset and progression of the disease including diet, antibiotics, stress, and bacterial infections, but no putative cause has been found. As diet and the gut biome play a significant role in disease progression, we aimed to find commonalities in the gut microbiomes of Crohn's patients, even when located in different geographical areas.

Infidelity in romantic relationships is common and has been associated with relationship dissolution and strain on individuals. Most religions teach that infidelity is harmful, and some researchers have suggested that, in the aggregate, more religious people might be less likely to report infidelity. However, research has been mixed, with some studies finding that more religious people are less likely to report infidelity, other studies finding that more religious people are more likely to report infidelity, and other studies finding no relationship. To clarify seemingly contradictory findings, I conducted a meta-analysis of the infidelity-religiosity relationship with 38 studies and a total sample size of over 35,000. A random-effects analysis found a small, statistically significant, inverse relationship between religiosity and infidelity (r = -.07, 95% CI [-.12, -.03]). However, a large degree of heterogeneity (Q = 1878.75.52, p < 0.001; I2 = 96.86) existed in this analysis, suggesting that effect sizes varied greatly between studies. In planned grouped comparisons, the relationship between religiosity and physical infidelity was not significantly different from the relationship between religiosity and emotional infidelity. Attendance at religious services and other measures of religiosity had similar relationships with infidelity, and spirituality and religiosity were equally protective against infidelity. Meta-regressions found that sample characteristics, such as race and gender, did not have a statistically significant relationship with the religiosity-infidelity effect size (p > .05), while publication status predicted effect size (p < .05). Findings are discussed through the lens of cognitive dissonance theory and intrinsic religious theory.

Personalized normative feedback (PNF) has shown promise as a stand-alone intervention for reducing alcohol use among college students. PNF uses norms clarification to correct drinking norms misperceptions by highlighting discrepancies between personal alcohol use, perceived peer alcohol use, and actual peer alcohol use. Previous reviews of personalized feedback interventions have identified norms clarification as key a component, prompting researchers to study PNF as a single-component intervention for college drinking. As the number of publications focused on PNF effectiveness has increased in recent years, an empirical review of these studies is warranted to assess the potential impact of PNF as a stand-alone program. The purpose of the present study was to summarize available research and to perform a meta-analytic review of personalized normative feedback as a stand-alone intervention for college student drinking. Studies were included if they examined a stand-alone PNF drinking intervention, used a college student sample, reported alcohol use outcomes, and used a pre-post experimental design with follow-up at least 28 days post-intervention. Eight studies (13 interventions) completed between 2004 and 2014 were included. Effect size estimates (ESs) were calculated as the standardized mean difference in change scores between treatment and control groups. Compared to control participants, students who received PNF reported a greater reduction in drinking and harms from baseline to follow-up. Results were similar for both gender-neutral and gender-specific PNF. Overall, intervention effects for drinking were small but reliable. This study offers an empirical summary of stand-alone PNF for reducing college student drinking and provides a foundation for future research.