No description available.

Abstract not available. / Thesis (M.Med.Sc.)-University of KwaZulu-Natal, 2008.

Self-reported health (SRH) tends to decline slower as people age compared to the decline of their objective health. If individuals believe they are in good health but actually are in poor health, their perceived susceptibility to disease may be low. Consequently, those individuals may feel less compelled to improve their health, which would make them a higher risk population. This project aims to examine the association of SRH and Metabolic Syndrome (MetS) in senior women, and whether personal and interpersonal dimensions help explain the degree to which SRH corresponds with MetS. Data are from the Kingston Senior Women Study (KSWS, n=100, 65 years of age and older). KSWS participants completed a questionnaire on their social background, psychosocial conditions, health behaviours, and SRH. Participants also provided physiological measures and medical information, so that MetS could be assessed, following the harmonized definition. MetS is a cluster of at least three of the following criteria: obesity, elevated blood pressure, low level of HDL cholesterol, raised triglycerides, and fasting plasma glucose. Two categories represented the correspondence between SRH and MetS: those who have a congruent perception of their health and those who overestimated it. Greater physical activity was associated with higher SRH (OR: 1.10; 95%CI: 1.01 – 1.20) and lower odds of MetS (OR: 0.64, 95%CI: 0.47 – 0.88) among the participants. However, only social network size was associated with lower odds of health overestimation (OR: 0.46, 95%CI: 0.26 – 0.80). Larger social networks may give access older women to a greater source of information about their own health, leading possibly to more accurate assessments of health. Such information can be conveyed as feedback from close ties. This information can also be conveyed as a more accurate perception of the health of their reference group when self-assessing their own health. Findings of this study may help identify women who are at greater risk of cardiovascular disease but who may be less likely to participate in health promotion programs. / Thesis (Master, Kinesiology & Health Studies) -- Queen's University, 2014-05-21 00:14:26.427

Motivation: The detrimental effects of obesity and insulin resistance in Caucasians and African-Americans have been the focus of many recent publications, and the association between PAI-1act and markers of the metabolic syndrome is well established but data on African subjects are still lacking. Objectives: To investigate possible differences between the association of PAI-1act with markers of the metabolic syndrome in Caucasian and African women. Methods We used cross-sectional data from the POWIRS I and II studies, involving 95 African and 114 Caucasian women respectively in the Potchefstroom district of the North West Province, South Africa. Results: Mean plasma PAI-1act was significantly higher in the Caucasian than in the African subjects (p < 0.001). Markers for the metabolic syndrome explained 60% of the variance of PAI-1act in the Caucasian group, but only 2.8% of the variance of PAI-1act in the African group. Waist circumference emerged as the strongest independent predictor of PAI-1act in the Caucasian (34%) as well as the African subjects (11%). Conclusion: This study showed clear differences in PAI-1act between African and Caucasian subjects, along with differences in the association of PAI-1act with markers of the metabolic syndrome. Apparent genetic differences between the two groups (especially the role of the 4G/5G genotype) may have an important influence on PAI-1act The role of PAI-1act in the metabolic syndrome may differ between Caucasians and Africans. / Thesis (M.Sc. (Nutrition))--North-West University, Potchefstroom Campus, 2005.

Background Physical inactivity causes obesity, a condition which is related to insulin resistance, hypertension, diabetes mellitus, dyslipidemia and the metabolic syndrome (MS). MS is the collective description of lifestyle diseases associated with significant morbidity and premature mortality. MS has recently been observed in youth, and if left untreated could lead to cardiovascular diseases. Regular physical activity (PA) and exercise training appear to modify the independent risk factors for MS and cardiovascular diseases, and has a positive effect on waist circumference, blood pressure, body fat percentage, insulin sensitivity and arterial compliance. Aims The aim of this study was to determine the relationship between body composition and selective markers of the MS, and the extent to which a PA intervention programme will influence selective markers of the MS, body composition and markers of vascular function in black adolescents. Methods Grade 9 classes from two high schools, in a low socio-economic status area near Potchefstroom, participated as the experimental and control group respectively. The experimental group consisted of 194 participants and the control group of 57 participants. The experimental group participated in a 10-week P A intervention. Body mass index, stature, body mass, waist-hip ratio, waist circumference, hip circumference, body fat percentage, fasting serum insulin, fasting plasma glucose, plasma leptin, homeostasis model assessment of insulin resistance (HOMA-IR), systolic blood pressure (SBP), diastolic blood pressure (DBP), Windkessel arterial compliance (Cw), total peripheral resistance, Tannerstage and habitual physical activity were measured. The data were analysed by means of descriptive statistics, Mann-Whitney U-tests, analysis of covariance (ANCOVA), Pearson's correlation analyses and multiple regression models. HOMA-IR and leptin were log transformed before analyses because of the skewed distribution. The Statistica for Windows and SAS computer programmes were used to analyse the data according to the above-mentioned aims of the study. Results and conclusions Firstly, a significant positive association was found between body fat percentage and both SBP (p=O.02) and HOMA-IR (p=O.02) respectively. Girls with a high body fat percentage had higher SBP (p=O.004), DBP (p=O.03), plasma insulin (p=O.004) and HOMA-IR (p=O.004) than girls with normal body fat percentage. Secondly, a 10-week PA intervention led to a significant decrease in SBP (p=O.000061), a trend of decreasing HOMA-IR, and a trend of increasing Cw in black adolescents. Lastly, no significant differences were found in body composition and vascular function variables for the normal-and over-fat group in this study after the 10-week PA intervention. In conclusion, the results of this study showed firstly, that there was a positive association between body fat percentage and SBP and HOMA-IR respectively; and secondly, that PA had a positive effect on some MS markers, namely: SBP and HOMA-IR. Further research regarding PA intervention's influence on the MS in black adolescents should be conducted, as there is clearly a shortage of literature that focuses on this research theme within this South African ethnic group. / Thesis (Ph.D. (Human Movement Science))--North-West University, Potchefstroom Campus, 2010.

Abstract   The development and onset of diseases such as cardiovascular disease (CVD) and Type 2 diabetes are closely linked to genetics and lifestyle factors including physical activity and diet. A cluster of metabolic disorders called the metabolic syndrome (MetS) is a high-risk factor in developing these diseases. Acording to the International diabetes institute, one fourth of the worlds adult population has MetS. These individuals are twice as likely to die from CVDs compared to individuals without MetS. Physical activity (PA) and exercise has been shown to provide a number of positive effects that are considered to reduce the risk of developing sickness and premature mortality among both men and women of all ages, independent of other risk factors.     Therefore our objective with this litterature-study was to establish the components of MetS, the relationship between PA, cardiorespiratory fitness and MetS, and the effects of exercise on MetS through intervention-studies.   Results: There are several components included in MetS and to be diagnosed with it you have to have at least three of the following: Abdominal obesity, hypertriglyceridemia, hypertension, abnormal glucose levels and/or low levels of HDL cholesterol. Close connections can be found between PA and CRF, and there are strong indications that an increase in PA and/or CRF have positive effects on the various components in MetS. This is supported by numerous intervention-studies with physical exercise targeting metabolic factors included in MetS.   Conclusion: The results indicate that PA and CRF have an important role to play in the prevention and treatment of the various components included in MetS. These variables can also, to some degree, predict the risk of developing MetS.     Key words: Metabolic syndrome, physical activity, cardiorespiratory fitness, relationship

Background Physical inactivity causes obesity, a condition which is related to insulin resistance, hypertension, diabetes mellitus, dyslipidemia and the metabolic syndrome (MS). MS is the collective description of lifestyle diseases associated with significant morbidity and premature mortality. MS has recently been observed in youth, and if left untreated could lead to cardiovascular diseases. Regular physical activity (PA) and exercise training appear to modify the independent risk factors for MS and cardiovascular diseases, and has a positive effect on waist circumference, blood pressure, body fat percentage, insulin sensitivity and arterial compliance. Aims The aim of this study was to determine the relationship between body composition and selective markers of the MS, and the extent to which a PA intervention programme will influence selective markers of the MS, body composition and markers of vascular function in black adolescents. Methods Grade 9 classes from two high schools, in a low socio-economic status area near Potchefstroom, participated as the experimental and control group respectively. The experimental group consisted of 194 participants and the control group of 57 participants. The experimental group participated in a 10-week P A intervention. Body mass index, stature, body mass, waist-hip ratio, waist circumference, hip circumference, body fat percentage, fasting serum insulin, fasting plasma glucose, plasma leptin, homeostasis model assessment of insulin resistance (HOMA-IR), systolic blood pressure (SBP), diastolic blood pressure (DBP), Windkessel arterial compliance (Cw), total peripheral resistance, Tannerstage and habitual physical activity were measured. The data were analysed by means of descriptive statistics, Mann-Whitney U-tests, analysis of covariance (ANCOVA), Pearson's correlation analyses and multiple regression models. HOMA-IR and leptin were log transformed before analyses because of the skewed distribution. The Statistica for Windows and SAS computer programmes were used to analyse the data according to the above-mentioned aims of the study. Results and conclusions Firstly, a significant positive association was found between body fat percentage and both SBP (p=O.02) and HOMA-IR (p=O.02) respectively. Girls with a high body fat percentage had higher SBP (p=O.004), DBP (p=O.03), plasma insulin (p=O.004) and HOMA-IR (p=O.004) than girls with normal body fat percentage. Secondly, a 10-week PA intervention led to a significant decrease in SBP (p=O.000061), a trend of decreasing HOMA-IR, and a trend of increasing Cw in black adolescents. Lastly, no significant differences were found in body composition and vascular function variables for the normal-and over-fat group in this study after the 10-week PA intervention. In conclusion, the results of this study showed firstly, that there was a positive association between body fat percentage and SBP and HOMA-IR respectively; and secondly, that PA had a positive effect on some MS markers, namely: SBP and HOMA-IR. Further research regarding PA intervention's influence on the MS in black adolescents should be conducted, as there is clearly a shortage of literature that focuses on this research theme within this South African ethnic group. / Thesis (Ph.D. (Human Movement Science))--North-West University, Potchefstroom Campus, 2010.

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Thesis (M.Sc.)--York University, 2006. Graduate Programme in Kinesiology and Health Science. / Typescript. Includes bibliographical references (leaves 50-71). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://proquest.umi.com/pqdweb?index=0&did=1299815841&SrchMode=1&sid=3&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1195667700&clientId=5220

Thesis (Ph.D.)--Baylor University, 2008. / Includes bibliographical references (p. 114-118).