Thesis (Ph.D.)--University of Oklahoma, 1987. / Includes vita. Bibliography: leaves 228-235.

Thesis (Ph.D.)--University of Delaware, 2009. / Principal faculty advisors: Norman J. Wagner, Dept. of Chemical Engineerin; and Eric W. Kaler, College of Engineering. Includes bibliographical references.

Thesis (Ph.D.)--University of Delaware, 2007. / Principal faculty advisor: L. Pamela Cook, Dept. of Mathematical Sciences. Includes bibliographical references.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1968. / Typescript. Vita. Includes bibliographical references.

Thesis (Ph.D.)--Ohio State University, 2005. / Title from first page of PDF file. Document formatted into pages; contains xxiii, 248 p.; also includes graphics. Includes bibliographical references (p. 226-248). Available online via OhioLINK's ETD Center

Thesis (Ph. D.)--University of Wisconsin--Madison, 1981. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 211-217).

Thesis (M.S.)--Rowan University, 2009. / Typescript. Includes bibliographical references.

Th. univ.--Chim.-sci. pétrolières--Paris 6, 1997. / Notes bibliogr. Résumé en anglais et en français. 1997 d'après la déclaration de dépôt légal.

The project was concerned with studying the capability of a micellar-enhanced ultrafiltration system (MEUF) to remove platinum group metal ions namely Pt (lV) and Pd (ll) chloro anions from aqueous industrial waste effluents. South Africa has the world’s largest reserves of platinum group metals (PGMs) and other valuable metals such as manganese, chrome ores, titanium minerals etc. which are required for new automotive and other technologies, including fuel cells, catalytic converters and lighter components. The consistent loss with the industrial waste stream and the toxicological effects of these precious metals led to the need to develop new and effective methods to recover them from industrial waste effluents. With such a wide variety of fields where these PGMs are used and the failure of the traditional techniques namely sedimentation, fermentation etc. to effectively reduce or recover these highly toxic and precious metal ions prior to discharging industrial waste effluents, it is necessary to explore other techniques such as membrane technology that can be used to recover these valuable species from industrial waste streams. The present study involved the use of a cationic surfactant, viz cetylpyridinium chloride, which was introduced into an aqueous solution containing palladium and platinum metal anions. The surfactant forms charged micelles above a certain critical concentration value. The metal anions adsorb onto the available oppositely charged sites on the micelle surfaces and are then able to be retained by a suitable membrane. Hollow fibre ultrafiltration membranes with the MWCO of +/- 10 kD and +/-30nm pore size were used as a filter component in this study. For this MEUF system to be effective, it was vital that the anionic metal ion species adsorbed sufficiently onto the available oppositely charged sites of the micelles and that the micelles were retained efficiently by the membrane. Results obtained during the investigation made it possible to make certain predictions about the micellisation process. It was also found that, it was not only the metal ion: surfactant (M:S) ratio that was critical, but the presence of other electrolytes in the aqueous stream proved to have a huge impact on the capability of the MEUF system. Findings of this research study showed that the MEUF system using cetylpyridinium chloride (CPC) can be used to recover or retain Pt (lV) and Pd (ll) anions from industrial waste effluents. It was also found that PtCl6 2-, due to its greater adsorption capabilities onto the micelle surface than PdCl4 2- or PdCl3(H2O)-, was preferentially retained in neutral medium. This may be exploited as a possible means of separating the two metal ions. The developed system offers the following advantages over some traditional and current methods: simplified unit operation line flow process, smaller amounts of chemical usage and no solid toxic sludge to be disposed of. Applications of this work could be of vital importance in catalytic converter recycling, especially in Port Elizabeth where extensive automobile parts manufacturing occurs.

De nombreux traitements anti-cancéreux ont été découverts au cours des dernières années. Cependant, ces derniers sont souvent responsables d'effets secondaires du fait de leur manque de spécificité.Le but de cette étude est de développer des formulations nanométriques de micelles pour améliorer le ciblage des cellules malades par ciblage passif et/ou actif. Les micelles peuvent être utilisées en tant que transporteurs de médicaments afin de les amener aux cellules cibles sans atteindre les organes sains.Des micelles polymérisées ont été développées pour cibler de manière passive les tissus tumoraux.Des micelles sensibles à certains stimuli comme la lumière ou le pH ont également été préparées pour assurer une libération contrôlée de principes actifs.Afin de conférer aux micelles des propriétés de ciblage actif, elles ont été fonctionnalisées par des ligands de ciblage. Les ligands présents à la surface du transporteur permettent un ciblage actif des cellules qui sur-expriment certains récepteurs.Enfin des micelles ont été développées pour pouvoir les utiliser comme agents de contraste en IRM. / Many drugs directed against cancer have been discovered over the past few years. However, the latter often induce severe side effects due to their lack of specificity.The aim of this study is to develop nanometric micellar formulations in order to improve the passive and/or active targeting of diseased cells. The micelles can be used as drug carriers to deliver drugs without affecting healthy organs.Polymerized micelles have been developed in order to passively target tumor tissues.Micelles sensitive to some stimuli such as light or pH have been prepared in order to ensure a controlled release of active compounds.In order to achieve active targeting, micelles were functionnalized with targeting ligands. These ligands at the carrier’s surface are responsible for active targeting of cells overexpressing some receptors.Some micelles have also been developed in order to be used as contrast agents in RMI.