The wall properties of the arteries play an important role in cardiovascular function. Stiffness of large artery is predictive of cardiovascular events. To understand the function of the cardiovascular system, special attention should be paid to the understanding of pulse wave propagation, because pulse waves carry information of the cardiovascular function, and provide information which can be useful for the prevention and diagnosis of diseases. This thesis presents a series of in vitro experimental studies of wave propagation, wave reflection and determination of mechanical properties of flexible vessels. In this thesis, several studies have been included: 1) applied and compared foot-to-foot, PU-loop and lnDU-loop methods for determination of wave speed in flexible tubes and calf aortas; 2) investigated the variation of local wave speed determined by PU-loop with proximity to the reflection site; 3) investigated using wave intensity analysis (WIA) as the analytical technique to determine the reflection coefficient; 4) developed a new technique which based on one-point simultaneous measurements of diameter and velocity to determine the mechanical properties of flexible tubes and calf aortas. In the first study, it is found wave speeds determined by PU-loop and lnDU-loop methods are very similar, and smaller than those determined by foot-to-foot method. The timing of arrival time of reflected wave based on diameter and velocity technique highly agreed with the corresponding timing based on pressure and velocity technique. The shapes of forward and backward non-invasive wave intensities based on diameter and velocity are very similar with the corresponding shapes based on pressure and velocity. Although the density term is not part of the equation, the lnDU-loop method for determining local wave speed is sensitive to the fluid density. In the second study, it is found wave speed measured by PU-loop is varied with proximity to the reflection site. The closer the measurement site to the reflection site, the greater the effect upon measured wave speed; a positive reflection caused an increase in measured wave speed; a negative reflection caused a decrease in measured wave speed. Correction iteration process was also considered to correct the affected measured wave speed. In the third study, it is found, reflection coefficient determined by pressure, square roots of wave intensity and wave energy are very close, but they are different from reflection coefficient determined by wave intensity and wave energy. Due to wave dissipation, the closer the measurement site to the reflection site, the greater is the value of the local reflection coefficient. The local reflection coefficient near the reflection site determined by wave intensity and wave energy are very close to the theoretical value of reflection coefficient. In the last study I found that distensibility determined by the new technique which utilising lnDU-loop is in agreement with that determined from the pressure and area which obtained from tensile test in flexible tubes; distensibility determined by the new technique is similar to those determined in the static and dynamic distensibility tests in calf aortas; Young’s modulus determined by the new technique are in agreement with that those determined by tensile tests in both flexible tubes and calf aortas. In conclusion, wave speed determined by PU-loop and lnDU-loop methods are very similar, the new technique lnDU-loop provides an integrated noninvasive system for studying wave propagation; wave speed determined by PU-loop is affected by the reflection, the closer the measurement site to the reflection site, the greater the change in measured wave speed; WIA could be used to determine local reflection coefficient when the measurement site is close to the reflection site; the new technique using measurements of diameter and velocity at one point for determination of mechanical properties of arterial wall could potentially be non-invasive and hence may have advantage in the clinical setting.

In this thesis, nondestructive surface wave measurements are presented for characterization of dynamic modulus and layer thickness on different pavements and cement concrete slabs. Air-coupled microphones enable rapid data acquisition without physical contact with the pavement surface. Quality control of asphalt concrete pavements is crucial to verify the specified properties and to prevent premature failure. Testing today is primarily based on destructive testing and the evaluation of core samples to verify the degree of compaction through determination of density and air void content. However, mechanical properties are generally not evaluated since conventional testing is time-consuming, expensive, and complicated to perform. Recent developments demonstrate the ability to accurately determine the complex modulus as a function of loading time (frequency) and temperature using seismic laboratory testing. Therefore, there is an increasing interest for faster, continuous field data evaluation methods that can be linked to the results obtained in the laboratory, for future quality control of pavements based on mechanical properties. Surface wave data acquisition using accelerometers has successfully been used to determine dynamic modulus and thickness of the top asphalt concrete layer in the field. However, accelerometers require a new setup for each individual measurement and are therefore slow when testing is performed in multiple positions. Non-contact sensors, such as air-coupled microphones, are in this thesis established to enable faster surface wave testing performed on-the-fly. For this project, a new data acquisition system is designed and built to enable rapid surface wave measurements while rolling a data acquisition trolley. A series of 48 air-coupled micro-electro-mechanical sensor (MEMS) microphones are mounted on a straight array to realize instant collection of multichannel data records from a single impact. The data acquisition and evaluation is shown to provide robust, high resolution results comparable to conventional accelerometer measurements. The importance of a perfect alignment between the tested structure’s surface and the microphone array is investigated by numerical analyses. Evaluated multichannel measurements collected in the field are compared to resonance testing on core specimens extracted from the same positions, indicating small differences. Rolling surface wave measurements obtained in the field at different temperatures also demonstrate the strong temperature dependency of asphalt concrete. A new innovative method is also presented to determine the thickness of plate like structures. The Impact Echo (IE) method, commonly applied to determine thickness of cement concrete slabs using an accelerometer, is not ideal when air-coupled microphones are employed due to low signal-to-noise ratio. Instead, it is established how non-contact receivers are able to identify the frequency of propagating waves with counter-directed phase velocity and group velocity, directly linked to the IE thickness resonance frequency. The presented non-contact surface wave testing indicates good potential for future rolling quality control of asphalt concrete pavements. / <p>QC 20170209</p>

Doctor of Philosophy / Department of Electrical and Computer Engineering / Pietro Poggi-Corradini / Caterina M. Scoglio / The modulus of a family of walks quanti es the richness of the family by favoring having many short walks over a few longer ones. In this dissertation, we investigate various families of walks to study new measures for quantifying network properties using modulus. The proposed new measures are compared to other known quantities. Our proposed method is based on walks on a network, and therefore will work in great generality. For instance, the networks we consider can be directed, multi-edged, weighted, and even contain disconnected parts. We study the popular centrality measure known in some circles as information centrality, also known as e ective conductance centrality. After reinterpreting this measure in terms of modulus of families of walks, we introduce a modi cation called shell modulus centrality, that relies on the egocentric structure of the graph. Ego networks are networks formed around egos with a speci c order of neighborhoods. We then propose e cient analytical and approximate methods for computing these measures on both directed and undirected networks. Finally, we describe a simple method inspired by shell modulus centrality, called general degree, which improves simple degree centrality and could prove to be a useful tool for practitioners in the applied sciences. General degree is useful for detecting the best set of nodes for immunization. We also study the structure of loops in networks using the notion of modulus of loop families. We introduce a new measure of network clustering by quantifying the richness of families of (simple) loops. Modulus tries to minimize the expected overlap among loops by spreading the expected link-usage optimally. We propose weighting networks using these expected link-usages to improve classical community detection algorithms. We show that the proposed method enhances the performance of certain algorithms, such as spectral partitioning and modularity maximization heuristics, on standard benchmarks. Computing loop modulus bene ts from e cient algorithms for nding shortest loops, thus we propose a deterministic combinatorial algorithm that nds a shortest cycle in graphs. The proposed algorithm reduces the worst case time complexity of the existing combinatorial algorithms to O(nm) or O(hkin2 log n) while visiting at most m - n + 1 cycles (size of cycle basis). For most empirical networks with average degree in O(n1􀀀 ) our algorithm is subcubic.

Characterization of rock masses and evaluation of their mechanical properties are important and challenging tasks in rock mechanics and rock engineering. Since in many cases rock quality designation (RQD) is the only rock mass classification index available, this paper outlines the key aspects on determination of RQD and evaluates the empirical methods based on RQD for determining the deformation modulus and unconfined compressive strength of rock masses. First, various methods for determining RQD are presented and the effects of different factors on determination of RQD are highlighted. Then, the empirical methods based on RQD for determining the deformation modulus and unconfined compressive strength of rock masses are briefly reviewed. Finally, the empirical methods based on RQD are used to determine the deformation modulus and unconfined compressive strength of rock masses at five different sites including 13 cases, and the results are compared with those obtained by other empirical methods based on rock mass classification indices such as rock mass rating (RMR), Q-system (Q) and geological strength index (GSI). It is shown that the empirical methods based on RQD tend to give deformation modulus values close to the lower bound (conservative) and unconfined compressive strength values in the middle of the corresponding values from different empirical methods based on RMR, Q and GSI. The empirical methods based on RQD provide a convenient way for estimating the mechanical properties of rock masses but, whenever possible, they should be used together with other empirical methods based on RMR, Q and GSI. (C) 2016 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting by Elsevier B.V.

Characterization of the effect of physical properties on the performance such as stiffness and drainage of unbound granular materials is necessary in order to incorporate them in pavement design. The stiffness, deformation and permeability behaviour of unbound granular materials are the essential design inputs for Mechanistic-Empirical Pavement Design Guide as well as empirical design methods. The performance based specifications are aimed to design, and construct a durable and cost effective material throughout the design life of a pavement. However, the specification varies among jurisdiction depending on the historical or current practice, locally available materials, landform, climate and drainage. A literature review on the current unbound granular materials virgin and recycled concrete aggregate base construction specification has been carried out in this study. Resilient modulus, permanent deformation and permeability tests have been carried out on seven gradations of materials from locally available sources. Resilient modulus stiffness of unbound granular material at two different conditioning stress level have been compared in the study. The long term deformation behaviour has also been characterized from results of the permanent deformation test using shakedown approach, dissipated energy approach and a simplified approach. The results show improvement in resilient modulus and permanent deformation for the proposed specification compared to the currently used materials as a results of reduced fines content, increased crush count and inclusion of larger maximum aggregate size into the gradation. A significant effect of particle packing on permeability of granular materials have also been found, in addition to the effect of fines. / October 2016

Patterned silver (Ag) columnar nanorods were prepared by the glancing angle physical vapor deposition method. The Ag columnar nanorods were grown on a Si (100) substrate patterned with posts in a square “lattice” of length 1 μm. An electron beam source was used as the evaporation method, creating the deposition flux which was oriented 85˚ from the substrate normal. A Dimension Icon with NanoScope V controller atomic force microscope was used to measure the spring constant in 10 nm increments along the long axis of five 670 nm long Ag nanorod specimens. The simple beam bending model was used to analyze the data. Unexpected behavior of the spring constant data was observed which prevented a conclusive physically realistic value of the Young’s modulus to be calculated.

Portable energy storage devices, which drive advanced technological devices, are improving the productivity and quality of our everyday lives. In order to meet the growing needs for energy storage in transportation applications, the current lithium-ion (Li-ion) battery technology requires new electrode materials with performance improvements in multiple aspects: (1) energy and power densities, (2) safety, and (3) performance lifetime. While a number of interesting nanomaterials have been synthesized in recent years with promising performance, accurate capabilities to probe the intrinsic performance of these high-performance materials within a battery environment are lacking. Most studies on electrode nanomaterials have so far used traditional, bulk-scale techniques such as cyclic voltammetry, electrochemical impedance spectroscopy, and Raman spectroscopy. These approaches give an ensemble-average estimation of the electrochemical properties of a battery electrode and does not provide a true indication of the performance that is intrinsic to its material system. Thus, new techniques are essential to understand the changes happening at a single particle level during the operation of a battery. The results from this thesis solve this need and study the electrical, mechanical and size changes that take place in a battery electrode at a single particle level. Single nanowire lithium cells are built by depositing nanowires in carefully designed device regions of a silicon chip using Dielectrophoresis (DEP). This work has demonstrated the assembly of several NW cathode materials like LiFePO4, pristine and acid-leached α-MnO2, todorokite – MnO2, acid and nonacid-leached Na0.44MnO2. Within these materials, α-MnO2 was chosen as the model material system for electrochemical experiments. Electrochemical lithiation of pristine α-MnO2 was performed inside a glove box. The volume, elasticity and conductivity changes were measured at each state-of-charge (SOC) to understand the performance of the material system. The NW size changes due to lithiation were measured using an Atomic Force Microscope (AFM) in the tapping mode. Electronic conductivity changes as a function of lithiation was also studied in the model α-MnO2 NWs and was found to decrease substantially with lithium loading. In other measurements involving a comparison between the alpha and todorokite phases of this material system, it was observed that the rate capability of these materials is limited not by the electronic but, by the ionic conductivity. Mechanical degradation of a battery cathode represents an important failure mode, which results in an irreversible loss of capacity with cycling. To analyze and understand these degradation mechanisms, this thesis has tested the evolution of nanomechanical properties of a battery cathode. Specifically, contact-mode AFM measurements have focused on the SOC-dependent changes in the Young’s modulus and fracture strength of an α-MnO2 NW electrode, which are critical parameters that determine its mechanical stability. These changes have been studied at the end of the first discharge step, 1 full electrochemical cycle, and 20 cycles. The observations show an increase in Young’s modulus at low concentrations of lithium loading and this is attributed to the formation of new Li-O bonds within the tunnel-structured cathode. As the lithium loading increases further, the Young’s modulus was observed to reduce and this is hypothesized to occur due to the distortions of the crystal at high lithium concentrations. The experimental-to-theoretical fracture strength ratio, which points to the defect density in the crystal at a given stoichiometry, was observed to reduce with electrochemical lithium insertion / cycling. This capability has demonstrated lithiation-dependent mechanical property measurements for the first time and represents an important contribution since degradation models, which are currently in use for materials at any size scale, always assume constant values regardless of the change in stoichiometry.

The increasing penetration of distributed generation, responsive loads and emerging smart metering technologies will continue the transformation of distribution systems from passive to active network conditions. In such active networks, State Estimation (SE) tools will be essential in order to enable extensive monitoring and enhanced control technologies. In future distribution management systems, the novel electrical power distribution system SE requires development in a scalable manner in order to accommodate small to massive size networks, be operable with limited real time measurements and a restricted time frame. Furthermore, a significant phase of new sensor deployment is inevitable to enable distribution system SE, since present-day distribution networks lack the required level of measurement and instrumentation. In the above context, the research presented in this thesis investigates five SE optimization solution methods with various case studies related to expected scenarios of future distribution networks to determine their suitability. Hachtel's Augmented Matrix method is proposed and developed as potential SE optimizer for distribution systems due to its potential performance characteristics with regard to accuracy and convergence. Differential Evolution Algorithm (DEA) and Overlapping Zone Approach (OZA) are investigated to achieve scalability of SE tools; followed by which the network division based OZA is proposed and developed. An OZA requiring additional measurements is also proposed to provide a feasible solution for voltage estimation at a reduced computation cost. Realising the requirement of additional measurements deployment to enable distribution system SE, the development of a novel meter placement algorithm that provides economical and feasible solutions is demonstrated. The algorithm is strongly focused on reducing the voltage estimation errors and is capable of reducing the error below desired threshold with limited measurements. The scalable SE solution and meter placement algorithm are applied on a multi-processor system in order to examine effective reduction of computation time. Significant improvement in computation time is observed in both cases by dividing the problem into smaller segments. However, it is important to note that enhanced network division reduces computation time further at the cost of accuracy of estimation. Different networks including both idealised (16, 77, 356 and 711 node UKGDS) and real (40 and 43 node EG) distribution network data are used as appropriate to the requirement of the applications throughout this thesis.

This Thesis deals with the determination of Young's modulus and Poisson's ratio from the measurement of small strains (10-3 - 10-5 ) in triaxial tests on the overconsolidated Miocene clay from Moravia (Brno Tegel). The tests were performed in a hydraulic triaxial chamber, fitted with submersible local LVDT sensors, which were fixed directly on the sample. The tests were carried out on undisturbed samples of standard height and diameter (76x38 mm). There were three types of tests - isotropic loading probe, axial loading probe and shear test to the failure. The measured data were analyzed and the results were discussed. The research part of the Thesis briefly describes previous works on stiffness of Brno Tegel and also some works on stiffness of similar material to Brno Tegel - London Clay.

Master of Science / Department of Architectural Engineering and Construction Science / Kimberly Waggle Kramer / Cold-formed steel framing sheathed with wood structural panels is a common method of construction for wall, roof and floor systems in cold-formed steel structures. Since wood structural panels are attached with screws at relatively close spacing, a certain amount of composite behavior will be present. However, the benefit of composite behavior of this system is currently not being taken advantage of in the design of these structural systems. While composite effects are present, they are not yet being accounted for in design due to a lack of statistical data. To determine the amount of composite action taking place in these systems, the slip modulus between steel and wood is required. The slip modulus reflects the amount of shear force able to be transferred through the screw connection, to either member of the composite system. This thesis presents the results of a study conducted to determine values of the slip modulus for varying thicknesses of cold-formed steel and plywood sheathing. Push tests were conducted and the slip moduli were determined based on ISO 6891 and ASTM D1761. Compared with data from a previous preliminary study performed by others, the values determined from these tests for the slip modulus were deemed reasonable. The determination of the slip modulus will lead to the ability to calculate a composite factor. Determination of a composite factor will allow cold-formed steel wood structural panel construction to become more economical due to the available increase in bending strength.