This thesis is concerned with the analysis of Cloud Computing as a solution for corporate information system and also its component for customer relationship management as a separate application in small and medium-sized companies. This thesis is also engaged in the research of small and medium-sized companies on the Czech market and finds the attitude of companies to applications run due to Cloud Computing solutions and what they think about Cloud Computing as such. The main objective of this work is to analyze the possibilities of this relatively new platform and highlight the the benefits and potential risks of their use. The work is divided into two parts. The first part focuses on the theoretical plane of Cloud Computing, where the basic concepts and limitations are defined and from which I will result my thesis. The second part is divided into four chapters. In the first subsection the ERP systems are compared, which are offered as a free version or as an Open Source suitable for use on Cloud Computing platform. In the second subsection the CRM systems are compared as a separate applications offered online as SaaS . The third section is devoted to the market research, which is focused on attitude and use of Cloud Computing applications in small and medium-sized companies . The final section offers the recommendations for MSP in the transition to Cloud Computing.

The main aim of the master's thesis is to clarify the problematic of small and medium-sized enterprises (SMEs), analyse relevancy and historical development of selected ratios influencing business environment conditions for SMEs, and determine the best country within V4 region in terms of favourableness of selected business environment conditions for 2014. Theoretical part of the thesis discusses the problematic of SMEs from different points of view emphasizing on the approach of European Union. Based on literature relevant indicators are selected and presented for each V4 country individually. Analytical part of the thesis analyses external environment conditions for SMEs within V4 region in 2014 through five groups of indicators: Taxation, Labour Cost, Demand, Corruption and Law Enforcement, and Easy of Doing Business. The whole analysis is conducted based on secondary data and method of indexes. All of the five groups of indicators are analysed separately and based on these results the final ranking is created. The results of the study show relatively similar business conditions for SMEs within V4 area with Poland having the best SMEs business environment in 2014.

This thesis is focused on analysis of competitiveness factors for small business enterprise in Czech and European environmnent. The theoretical part represents possible types of attitudes and analysis to management, marketing, human resources management and financial management. The practical part demonstrates application of theoretical knowledge at specific company, micro-enterprise, IMPORTO Drive s.r.o. dealing with buying and selling of new cars in EU. The objective of this thesis is to design appropriate steps providing the long - term developmnent of analyzed company taking it`s vision fulfillment into consideration. Inspiration for future enterpreneurs could be also one benefit.

This master thesis deals with the analysis of the possibilities of Cloud Computing for information system solutions in small and medium businesses. The main objective is to analyze these options, identify key areas for the transition to the cloud and propose an approach to develop Information system in this direction. The main contribution of this work is the practical experience which is involved in a view of the problems being solved and an emphasis on aspects that have been verified in practices. The main text of the work is divided into five chapters. The first chapter defines the basic concepts and limitations on which further work is based. The second chapter deals with the current form of IS in SMEs, its description and identifying problems. The third chapter analyzes the Cloud Computing from the perspective of the suitability of various models for SMEs, identifies the major trends that affect the Cloud Computing and describes some basic elements on which Cloud Computing is based. It also analyzes the issue of security. The fourth chapter deals with the state of Cloud Computing market and identification of key problem areas which need to be solved in various stages of market development. The last chapter uses several case studies to show a meaningfulness and readiness of Cloud Computing for running information system. In the end the recommended approach to the adoption of cloud services is defined.

The aim of the diploma thesis is the analysis of enhancing the competitiveness of small-sized enterprise applied to a particular company. The theoretical part specifies the basic characteristics of "small and medium-sized enterprises" and the factors of competitiveness, which are divided into four basic areas of business management -- management, marketing, human resource management and financial management. The practical part is related to theoretical piece of knowledge applied to the company "FCC Industrial Systems Ltd.". The result of the company analysis is suggesting of recommendations aimed for enhancing the competetiveness.

Increasing amount of consulting companies offering support for implementation of norm ISO/IEC 20000 and their assurance that this norm is suitable for any type of organization is bringing a question if it is in reality true. The text is considering methodologies of information processes management in MSP and is highlighting problems that can arise in this segment. The work consists of theoretical outputs as well as experience from planning the implementation of ISO 20000 in a small Business Intelligence company. In the first part of this work are methodologies put in general frame of informatics management (IT Governance) and is discussed their purpose and impacts of standardization of management processes to which their use is leading. The main attention is paid to ITIL and ISO 20000 and their mutual relationship. In both methodologies is apprised suitability for segment MSP. In scope of the practical part are defined conditions that need to be fulfilled in order to achieve successful implementation of ISO 20000 in MSP. The main output of this part is concrete methodology of implementation of ISO 20000 in a small company.

Snow Spell is an interactive composition for erhu, flute, cello, piano, and Max/MSP interactive computer music system. This one-movement piece, Snow Spell, is intended to depict the beauty of a snow scene by presenting four different impressions of snow envisioned by the composer through music. The definition, history, and significance of interactive music are explored. Various modes of interactivity to control signal processing modules, and technical considerations for signal routing and level control in the interactive computer music system are also explored. Chinese music elements in Snow Spell including pentatonic scales, glissandi, and quotations from the Chinese folk tune River of Sorrow are investigated.

Following work deals with evaluation of current situation in a company PRUMHOR s.r.o. and brings some suggestions for improvement of its management. The first part considers the analysis of the potential of family business and small and medium enterprises at the theoretical basis and points out to the most important specifics concerning the general principle. The second part is focused on its environment and analysis of factors with which is the company influencing its market surroundings. The third part includes the proposal of support of future development.

This diploma thesis deals with the identification of the effect of e-commerce and relevant influenced factors in the case of manufacturing Small and Medium-sized Enterprises (SMEs). The observation is specified mainly for SMEs as such, for Slo-vak SMEs, and partially for SMEs from EU countries. The theoretical part creates a full-fledged background for the following observations. The practical part consists of a gradual observation focused on the state and impact of e-commerce on Slo-vak manufacturing SMEs and additional observation of the selected company from the relevant segment, for a more detailed view of the issue. Moreover, it in-cludes addressing the issue with analysis of various financial indicators, selected comprehensive financial analysis, and, last but not least, various descriptive ob-servations through which the results are provided, linked to the impact of e-commerce on a given business segment. These findings are finally discussed, and relevant conclusions are drawn, in the final part.

Androgens are the main regulators of human hair growth stimulating larger, terminal hair development e.g. beard and causing scalp balding, androgenetic alopecia. Hair disorders cause psychological distress but are poorly controlled. Androgens probably act by altering regulatory paracrine factors produced by the mesenchyme-derived dermal papilla. This study aimed to investigate paracrine factors involved in androgen-regulated alopecia, particularly hepatocyte growth factor (HGF) family members, by investigating their in vivo status. Balding and non-balding scalp hair follicles and their component tissues were isolated and analysed by molecular biological methods (reverse transcriptase-polymerase chain reaction (RT-PCR), quantitative PCR and DNA microarray analysis), cell culture and immunohistochemistry. Scalp follicles expressed a range of paracrine messenger genes. The dermal papilla, cultured dermal papilla cells and dermal sheath expressed several HGF family genes, while matrix cells only produced the receptor RON suggesting autocrine roles for HGF and MSP, but a paracrine route only for MSP. Comparing balding and non-balding follicles from the same individuals revealed the expected reduction in several keratin and keratin-related protein genes supporting this approach's validity. There were also significant differences in paracrine factors previously implicated in androgen action by in vitro studies. Several factors believed to increase during androgen stimulation of larger, darker follicles, e.g. IGF-I and SCF, were lowered in balding follicles, while putative inhibitory factors, e.g. TGFß-1, were increased. HGF and MSP and their receptors, c-Met and RON, were significantly reduced. These results increase our understanding of androgen action in human hair follicles; this could lead to better treatments for hair disorders. / Saudi government