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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
121

Eficácia da estimulação intramuscular no tratamento da dor miofascial crônica

Couto, Cláudio Luiz Mendes January 2009 (has links)
Cenário clínico: A síndrome dolorosa miofascial (SDM) pode ser incapacitante e desafiadora terapeuticamente, devido à ineficácia dos tratamentos convencionais para a dor. Objetivos: O objetivo deste estudo foi avaliar a eficácia da estimulação intramuscular (EIM) na redução da dor e melhora da saúde física e mental de pacientes com SDM. Conduzimos um ensaio clínico randomizado controlado em 60 mulheres, com idades entre 20 e 40 anos, que foram randomizadas para receber EIM, infiltração com lidocaína e falsa eletroneuroestimulação transcutânea (TENS-placebo), duas vezes por semana, durante 4 semanas. Resultados: A redução do percentual de alívio de dor observada na escala análogo-visual de dor (EAVD) durante a primeira semana após o final do tratamento no grupo TENS-placebo foi de 14,01 [intervalo de confiança (IC) 95%; 2,89 a 25,12], o que foi significativamente menor em comparação com o observado nos grupos de infiltração com lidocaína e de EIM, de 43,86% [IC 95%; 26,64 a 61,08] e de 49,74% (IC 95%, 28,95 a 70,54), respectivamente. O tamanho do efeito (TE) sobre a dor, na comparação de TENS-placebo com a EIM e infiltração com lidocaína foi de 1,48 [IC 95%; 0,76 a 2,19] e de 1,20 [0,43 a 1,40], respectivamente. O tamanho do efeito (TE) sobre a dor, na comparação de TENS-placebo com a EIM e infiltração com lidocaína foi de 1,48 [IC 95%; 0,76 a 2,19] e de 1,20 [0,43 a 1,40], respectivamente. A EIM melhorou significativamente os escores da saúde física e mental e o limiar de dor à pressão (LDP). Valores baixos do LDP, antes do tratamento, preveem uma redução do risco de 43% para apresentar um TE pequeno/moderado na dor no grupo da EIM e atitudes positivas, em todas intervenções, aumentaram a probabilidade para uma redução significante na intensidade da dor relatada.. Conclusões: A EIM foi mais efetiva do que o TENS-placebo e pelo menos equivalente à infiltração com lidocaína no tratamento da SDM e na melhora dos sintomas depressivos e da saúde física e mental. / Background: Myofascial pain syndrome (MPS) can be disabling and therapeutically challenging, because of the inefficacy of traditional pain treatment. Objectives: The objective of this study was to evaluate the efficacy of intramuscular stimulation (IMS) in reducing pain and improving physical and mental health in patientes with MPS. Methods: We conducted a controlled trial in 60 females, aged 20 to 40 years, where the participants were randomized to receive IMS, lidocaine infiltration or TENS-placebo twice a week for 4 weeks. Results: The reduction in the percent pain on a VAS (Visual Analogue-Scale) after the end of the first week of treatment in the TENSplacebo group was 14.01 [95% confidence interval (CI); 2.89 to 25.12], which was significantly lower than for the lidocaine infiltration and IMS groups, which reported 43.86% [95% CI; 26.64 to 61.08] and 49.74 % (95% CI, 28.95 to 70.54), respectively. The ES (effect size) on pain comparing TENS-placebo vs. IMS and TENS-placebo vs. lidocaine-infiltration were 1.48 [95% CI; 0.76 to 2.19] and 1.20 [0.43 to 1.40], respectively. IMS significantly improved the mental and physical health scores and the PPT. Lower PPT values pretreatment predicted a reduction of the risk by 43% of the small/moderate ES in terms of pain in the IMS group and positive attitudes, in all interventions, improved the probability a significant reduction in current pain intensity. Conclusions: IMS was more effective than TENS-placebo and at least equivalent to lidocaine infiltration in treating MPS and improving physical and mental health.
122

Dor muscular e temperatura muscular: estudo termográfico longitudinal / Muscle Pain and Muscle Temperature : A longitudinal thermographic study

Marcelo Weber 14 July 2016 (has links)
Embora as causas de DTM tenham sido muito estudadas e discutidas na literatura atual, a associação entre a dor muscular e sua temperatura não está totalmente clara. Para esta investigação, 40 pacientes com dor muscular foram encaminhados da clínica odontológica e foram examinados. Um total de 31 pacientes foram diagnosticados com dor miofascial no musculo masseter pelo RDC e foram incluídos neste estudo. O musculo masseter no lado com dor foi anestesiado e foi comparado ao lado oposto ao longo do tempo. Na análise estatística de comparação, foi encontrada associação entre o aumento de temperatura e a diminuição da dor relatada. Possíveis fatores de confusão, como tempo da dor crônica, idade, índice de massa corpórea, pontos de incapacidade, ICD, pior dor sentida nos últimos meses e dor media nos últimos meses foram levados em consideração e foram estatisticamente analisados e o único fator que mostrou estatisticamente correlação com a diminuição da dor foi o fator tempo. Conclusão: existe uma correlação negativa entre o aumento de temperatura e a diminuição da dor. / Although, TMD causes have been widely studied in the last years, the association between muscle pain and temperature remains unclear. For this investigation, 40 muscle pain patients were referred from dental clinic and were examined. A total of 31 patients were diagnosed with masseter myofascial pain by RDC criteria and were included in this study. Masseter muscle was blocked in the pain side and was compared among the time to opposite side. In the matching statistics association analysis, it was found association between temperature increase and related pain decrease. Possible confounders (time of chronic pain, age, Body Mass Index, ICD, incapacity points, worst pain in the last six months, average pain in last six month) were took in consideration and only time since the pain started seems to be related to decrease in pain. Conclusion: there is a negative association between muscle pain and muscle temperature.
123

Associação entre bruxismo do sono e dor miofascial: um estudo polissonográfico / Association Between Sleep Bruxism and Myofascial Pain: a Polysomnographic Study.

Leylha Maria Nunes Rossetti 28 August 2006 (has links)
Objetivos: Verificar 1) a presença de associação entre bruxismo do sono (BS) e dor miofascial (DMF); 2) se há correlação entre atividade rítmica dos músculos mastigatórios (ARMM) e os valores de limiar de dor à pressão matinais (LDP-pósPSG); 3) se maiores níveis de dor ou sensibilidade à palpação correlacionam-se com menores índices de ARMM em bruxômanos e não bruxômanos com e sem DMF e 4) avaliar a confiabilidade do exame clínico de bruxismo (ECB) Material e Métodos: Realizaram-se exame PSG (2 noites consecutivas) e ECB em 30 pacientes com DMF e 30 indivíduos assintomáticos, correspondentes em sexo e em idade. Previamente à PSG (2a noite) verificou-se o LDP (pré- PSG) da origem, corpo, inserção e porção profunda do masseter e porções anterior, média e posterior do temporal. Na manhã seguinte, verificou-se o LDP pós-PSG nos mesmos sítios musculares. Resultados: Todos os pacientes com DMF apresentaram queixa de dor nos músculos mastigatórios (temporal e/ou masseter), 90% relataram dor leve ou moderada, com duração média de 34,67 ± 36,96 meses (2 a 120). Não houve diferenças entre os grupos quanto à macroestrutura do sono. Houve associação significativa entre BS e DMF [(Quiquadrado, p = 0,039); OR 3,45 (IC 95% 1,066 - 11,194); RR:1,83 e LR+: 1,9. Apenas entre os pacientes de DMF houve correlações negativas entre ARMM e LDP pós-PSG. As correlações foram mais fortes entre os pacientes não-bruxômanos do que nos pacientes bruxômanos. Apenas entre os bruxômanos assintomáticos houve correlações positivas entre LDP pré-PSG e ARMM. Conclusões: 1) O BS associou-se com DMF; 2) a DMF parece ser fator predisponente à maior sensibilidade matinal à palpação; 3) não bruxômanos com DMF parecem responder com maior sensibilidade matinal à palpação a aumentos na intensidade da ARMM do que bruxômanos com DMF; 4) apenas entre os bruxômanos assintomáticos encontrou-se suporte à ocorrência do mecanismo de adaptação à dor e 5) o ECB apresentou valores distintos de confiabilidade para a população com DMF e assintomática, apresentando valores mais altos na população com DMF, embora não tenha atingido os níveis adequados de sensibilidade (75%) e especificidade (90%). / Objectives: To test 1) the association between sleep bruxism (SB) and miofascial pain (MFP); 2) the correlation between rhythmic masticatory muscle activity (RMMA) and pressure pain threshold (PPT) at morning, 3) the influence of previous tenderness over RMMA in bruxers and non-bruxers with/without MFP, and 4) the validity of a clinical diagnostic criteria of sleep bruxism (DCSB). Materials and Methods: Polysomnographic recording (PSG) (two consecutive nights) were performed in 30 MFP patients, selected according to RDC/TMD and 30 asymptomatic controls age and gender-matched. Pre and post-PSG PPT values were verified for masseter (origin, body, insertion, and deep portion), as well as for temporal (anterior, medium, posterior) muscles. Results: All MFP patients reported pain complaints on masseter and/or temporal muscles. Most of MFP patients reported mild or moderate pain (46.67%, and 43.33%, respectively), and only 3 (10%) reported severe pain. Pain duration ranged from 2 to 120 months (mean of 34.67 ± 36.96 months). No differences in sleep architecture were observed in both groups. A significant association was observed between SB and MFP [Chi-Square=0.039, Odds Ratio=3.45 [CI 95% 1.066-11.194)]. Only in MFP patients negative correlations were seen between ARRM and morning-PPT ? indicating a dose-response gradient between ARRM and tenderness to palpation on morning. This gradient seemed more evident among MFP non-bruxers than on bruxers. There were positive correlations between pre-PSG PPT and RMMA only among asymptomatic bruxers. Conclusions: These findings indicate that: 1) Sleep bruxism is significantly associated with MFP; 2) MFP seems to be a predisposing factor that increases bruxism-related muscle sensitivity; 3) MFP non-bruxers seem to show more tenderness on palpation due to more intense RMMA than do MFP bruxers. 4) Only among asymptomatic bruxers was found some evidence of pain-adaptation model; and 5) The DCSB showed different confiability values for MFP and asymptomatic patients, presenting higher values for MFP patients, although not reaching adequate sensitivity (75%) and specificity (90%) levels.
124

Avaliação da eficácia do agulhamento de pontos-gatilho miofasciais (seco, 0,5% e 1% de lidocaína) em pacientes portadores de dor miofascial na musculatura mastigatória / Evaluation of dry needling, 0,5% lidocaine injection and 1% of lidocaine injection therapies in myofascial pain trigger points in maticatory muscles

Renato Oliveira Ferreira da Silva 17 September 2007 (has links)
Avaliou-se a eficácia do tratamento através da técnica de agulhamento a seco, com injeção de lidocaína a 0,5% e injeção de lidocaína a 1% em pacientes portadores de dor miofascial e na presença de pontos-gatilho em músculos da mastigação. Foram selecionados 26 pacientes e divididos em três grupos: Grupo I: pacientes submetidos a injeção de lidocaína a 0,5%. Grupo II: Pacientes submetidos à injeção de lidocaína a 1%. Grupo III: Pacientes submetidos ao agulhamento a seco. Avaliou-se os pacientes através do limiar de dor a palpação (LDP) e da escala de análise visual de dor (EAV) nos períodos: inicial (antes da infiltração), imediatamente após a infiltração, 24 horas depois, 7, 15, 21 e 30 dias respectivamente. Os resultados foram coletados e analisados através do teste anova a 2 critérios adotando-se nível de significância de 0,05%. Onde houve diferenças estatísticas significantes, aplicou-se o Teste de Tukey. Não houve diferenças estatísticas significantes entre os três grupos quando comparados o LDP entre os grupos, porém houve diferenças significantes quando comparado o LDP ao longo do tempo, sendo que este aumentou significativamente. Em relação à EAV, acharam-se diferenças tanto entre os grupos quanto ao longo do tempo, sendo que o grupo X teve uma diminuição mais rápida do que os outros dois. Porém, ao final, todos os grupos tiveram reduções significantes e sem diferenças entre si. Conclui-se que todos os tratamentos foram eficazes na redução dos sintomas da dor miofascial no tempo avaliado, não havendo diferenças entre os tratamentos. / The purpose of this study was to compare the effectiveness of trigger points injections using lidocaine 0,5%, lidocaine 1% and dry needling without any kind of home-based rehabilitation program. 26 patients with myofascial pain and trigger points in masticatory muscles. They were randomly assigned in three groups and received only one application session. The pressure pain threshold (PPT) was recorded before the injection, ten minutes after, 24 hours later, 7, 15, 21 end 30 days after the treatment. Visual analogue scale (VAS) was used to in all evaluation periods. There were no differences between groups for PPT. but for all groups, the PPT during the time significantly increased when compared the before treatment. VAS showed differences between groups and during the time. VAS was significant lower when compared 30 days to before treatment. Among the groups, 0,5% lidocaine ha the lowest VAS values when compared to the others, but at 30 days there were no differences among them. Despite the differences in VAS and considering there were no differences in PPT increases, we concluded that, in this study, all groups were able to disrupt the mechanisms of trigger point and relieve the myofascial pain symptoms.
125

The effectiveness of chiropractic adjustments with ischemic compression or ultrasound on active levator scapulae trigger points in physically active people

Bosch, Leonie 09 October 2014 (has links)
M.Tech. (Chiropractic) / The aim of the study was to compare the efficacy of treating the active levator scapulae trigger point (TP1) with either chiropractic adjustments combined with ischemic compression or chiropractic adjustments combined with ultrasound therapy in physically active people in order to determine which of the two treatment protocols was superior.This study was a comparative study consisting of two groups of fifteen participants each. Participants were between the ages of eighteen and forty-five and there was an equal male to female ratio. Prior to becoming a participant in this study individuals were assessed according to the inclusion and exclusion criteria. The International Physical Activity Questionnaire, a clinical case history, full physical examination, a cervical regional examination and examination of the levator scapulae muscle for an active central trigger point (TP1) were completed. The method of treatment for each participant was determined by random group allocation. Group 1 received cervical spine chiropractic adjustments combined with ischemic compression to the active levator scapulae trigger point. Group 2 received cervical spine chiropractic adjustments combined with ultrasound therapy to the active levator scapulae trigger point. Subjective and objective readings were based on the above treatment protocols.Treatment consisted of seven consultation sessions over a three week period. There were six treatment visits with the seventh visit used only for data collection. There were two treatments each week with at least two days in between visits. The third week consisted of three visits with the last visit used only for data collection. Subjective data was collected from the Vernon-Mior Neck Pain and Disability Index Questionnaire and the Numerical Pain Rating Scale. Objective data was collected from the pressure algometer readings. Subjective and objective data was collected before treatment on the first and fourth visits and on the seventh final data collection visit. Analysis of the data collected was done by a statistician. The chiropractic adjustments used were based on motion palpation findings on the treatment visits and re-assessed on each visit.Clinically significant improvements regarding neck pain and disability and trigger point severity were seen in both Group 1 and Group 2 over the three week period. Group 2 showed greater improvements in all subjective and objective readings over the three weeks compared to Group 1.
126

The effectiveness of myofascial deep dry needling versus superficial dry needling in the treatment of Trapezius Myofascial Pain Syndrome

Glanz, Kelly 07 June 2012 (has links)
M.Tech. / Purpose: The purpose of this study is to investigate whether needling active trigger points in the upper fibres of the trapezius muscle, using myofascial deep dry needling versus superficial dry needling is effective in the treatment of Trapezius Myofascial Pain Syndrome. Method: Forty participants underwent a general screening to determine whether they have active myofascial trigger points in the upper fibres of the Trapezius muscle. The general screening was done by using a pincer grip technique to find the active trigger point within the trapezius. If the pincer grip revealed that there were active trigger points, the participant was suitable for this study. Each filled in a neck disability index and a pain rating scale, with algometer readings taken Pre and Post-treatment on visit 1 to visit 4. Algometer readings were taken at the active trigger point Pre and Post-treatment (subjective data). Each participant received either myofascial deep dry needling or superficial dry needling to the active trigger point. After the two week trial, the participants had to fill out a neck disability index and a pain rating scale for a second time in order to objectively measure the participants pain. Results: The results were interpreted by Statkon at the University of Johannesburg. The data was analysed using the Mann Whitney test and the Friedman test. According to the tests, both groups improved significantly in both the objective and subjective measurements over the four visits. Overall, the mean values for both the myofascial deep dry needling group and the superficial dry needling group were P = 0.001. The superficial dry needling group showed a further increase over a short term period in the objective and subjective measurements over each visit. Conclusion: Based on the results of this study, it can be concluded that both myofascial deep dry needling and superficial dry needling is effective and can be used in the treatment of Trapezius Myofascial Pain Syndrome. This study further indicated that superficial dry needling was shown to be a significantly effective treatment short term when compared to that of myofascial deep dry needling of active trigger points in the upper fibres of the Trapezius muscle
127

The effectiveness of the Impulse Adjusting Instrument® compared to dry needling in the treatment of upper trapezius myofascial trigger points

Laing, Mandy January 2017 (has links)
Submitted in partial compliance with the requirements for the Master’s Degree in Technology: Chiropractic, Durban University of Technology, Durban, South Africa, 2017. / Aim: There is a paucity in the literature regarding the effectiveness of the Impulse Adjusting Instrument® (IAI) in treating myofascial trigger points (MFTPs) and regarding the effectiveness between dry needling and the IAI in the treatment of MFTPs. There are many limitations and an array of contraindications for dry needling. Therefore, an alternative method should be sought as this will be beneficial to the patient. Thus, the aim of this study was to determine the effectiveness of the IAI compared to dry needling in the treatment of MFTPs found in the upper trapezius muscle. Methodology: This study was a randomised single-blinded clinical trial. This study consisted of 41 participants between the ages of 18 and 40 who were divided into two groups. The participants were randomly allocated into their respective groups using a blinded allocation method that was drawn up by the statistician. Groups were divided into dry needling (Group one (n=18)) and IAI (Group two (n=23)) treatment groups. Subjective neck pain level was determined using a numerical pain rating scale (NRS). The neck disability index (NDI) subjectively assessed the effect neck pain had on the participants’ activities of daily living before and after treatment. The Patients Global Impression of Change (PGIC) tool was used to determine the participants’ subjective impression of treatment outcomes since the beginning of the treatment. Objective pain pressure thresholds (PPT) were measured with an algometer. Objective cervical range of motion (CROM) in lateral flexion (LF) was measured with a goniometer. Each participant had four visits over a two week period, which included three treatments and a final visit for final measurements. Data was analysed using IBM SPSS version 23. Repeated measures ANOVA was used to examine the effect on each outcome measure. Directional trends in effectiveness were drawn up using profile plots to assess the direction and trends of the effects. A p value of < 0.05 was considered to be statistically significant. Results: Intra-group and inter-group statistical analysis revealed all subjective measurements improved in both groups with no significant differences between the groups. With respect to objective measurements, there was no statistical improvement in LF CROM and dry needling had no improvement in PPT. Impulse Adjusting Instrument trigger point therapy showed an increase in PPT, however, when compared to dry needling there was no statistical difference in PPT. Conclusion: The conclusion for this study states that the trends in each of the outcomes suggest that the IAI is as effective as dry needling for the treatment of MFTPs. / M
128

A comparative investigation into the treatment of active myofascial trigger points with dry needling therapy versus low level laser therapy

Burger, Amand Gerhard 17 April 2013 (has links)
M.Tech. (Chiropractic) / A myofascial trigger point is a hyperirritable point within a tight band of voluntary skeletal muscle. The condition causes levels of mild discomfort to intense pain to patients that usually results in loss of man hours and compulsory pain medication. Dry needling is the treatment of choice and other techniques are seldom considered. Dry needling therapy (DNT) is an effective tool in the chiropractic profession but comes with significant drawbacks, such as patients whom have needling phobias and patients who often experience post needling soreness are challenging to treat with DNT. Further and more serious risks include pneumothorax when needling the muscles over the lung fields, which also limits the treatment scope of DNT. Low level laser therapy (LLLT) is non-invasive and non-threatening to patients and could serve as an alternative to DNT. This study therefore aimed, to determine if LLLT could be an alternative treatment to DNT by comparing DNT to LLLT on a target group that all have active trapezius trigger point two myofascial trigger points. The group consisted of 40 participants with posterior trapezius myofascial neck pain caused by active myofascial trapezius trigger points. Participants were then randomly divided into two groups. Group A (20 participants) would receive DNT to the active myofascialtrapezius trigger point two (TP2) and group B (20 participants) would receive LLLT also to the active myofascial trapezius TP2. Participants would then be treated according to a set protocol, over a two week period with a total of four treatments. Subjective and objective readings were taken and noted on the first, third and fifth visits. Subjective data was collected from the visual analogue scale and the Vernon-Minor neck pain and disability index questionnaires. Whereas the cervical range of motion (CROM) and algometer readings provided the objective data.
129

A comparative study between low level laser therapy and myofascial dry needling on active gluteus medius trigger points

Van Heerden, Marili 13 October 2014 (has links)
M.Tech. (Chiropractic) / Myofascial trigger points (MTrP’s) cause acute discomfort to intense pain and often lead to the use of pain medication as well as loss of man hours (Simons, Travell and Simons, 1999a; Tough, White, Cummings, Richards and Campbell, 2009). Dry needling is very effective and is widely used for the treatment of MTrP’s (Vulfsons, Ratmansky and Kalichman, 2012), but comes with various significant drawbacks, such as the experience of pain during or after treatment (post-needling soreness) or individuals with needle phobias (Unruh, Strong and Wright, 2002). More serious risks also exist, including damage to the viscera (Dommerholt and Fernández-de-las-Peñas, 2013). Low level laser therapy (LLLT) is a non-invasive technique and very little discomfort or pain is experienced by the patient during and after treatment. LLLT is effective in the short- and long-term relief of trigger points and myofascial pain syndrome. Therefore it can easily serve as an alternative to myofacial dry needling (Chow and Barnsley, 2005). This study aimed to determine whether LLLT or myofascial dry needling is more effective in the treatment of active MTrP’s, specifically those of the gluteus medius muscle. It also aimed to determine if LLLT could serve as an alternative treatment to dry needling in cases where dry needling is contraindicated or not desired. Thirty participants who complied with the inclusion criteria were divided into one of two groups. Group 1 (n=15) received dosages of LLLT directly to the active MTrP’s in the gluteus medius muscle and Group 2 (n=15) received myofascial dry needling to active MTrP’s in the gluteus medius muscle. Each participant attended 6 treatment sessions over a course of 2 weeks as well as a 7th measurements-only session.
130

Activator instrument versus dry needling of active upper trapezius myofascial trigger points in those with neck pain

Siphuma, Winnie Mulalo 17 April 2013 (has links)
M.Tech. (Chiropractic) / Neck pain is a common and costly complaint in society and many are made to believe that their neck pain is caused by pinched nerve, compressed disk, arthritis or displaced cervical vertebrae, when in reality the pain may be solely due to referral from myofascial trigger points in overworked or traumatized muscles of their upper back and shoulders. Travel and Simons (1999) demonstrated trapezius muscle of the neck, back and shoulder as the main cause of mechanical neck pain and stiffness. The aim of this study was to compare the effects of trigger point therapy using an activator instrument versus myofascial dry needling in combination with cervical spine adjustment in the treatment of those with acute or chronic neck pain associated with active trigger point 1 (TrP 1) or trigger point 2 (TrP 2) of upper trapezius muscle, with regards to pain and disability, pressure pain threshold and cervical spine range of motion. The clinical study consisted of forty participants, from the ages of 18 and 45, randomly allocated into two groups of twenty individuals each. Potential participants were examined and accepted based on inclusion and exclusion criteria. Group 1 received activator trigger point therapy to upper trapezius TrP 1 or 2 with chiropractic adjustment to restricted segments of the cervical spine, and group 2 received myofascial dry needling of upper trapezius TrP 1 or 2 with chiropractic adjustment to restricted segments of the cervical spine. Participants were treated four times over a period of two weeks. Subjective data was collected using the Vernon-Mior Neck Pain and Disability Index and a Visual Analog Scale. Objective data was collected using an algometer to measure pressure pain threshold of trapezius TrPs muscles, and a goniometer to measure cervical spine range of motion. All data was collected at the first and third visits prior to treatment, and at the fifth visit. The statistical analysis was conducted using nonparametric tests. Friedman’s test was used to assess whether neck pain, disability, cervical spine range of motion and pressure pain threshold varied over the three time intervals. Wilcoxon Signed Ranks Pair test was used for assessment of comparability of the results in each group separately, and the Mann-Whitney U test was used for comparison of the accumulated data in the two groups.

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