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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 51 to 60 of 785 (0.026 seconds)| 51 |
An experimental investigation of the potential of radioisotope infarct markers to quantify injury in donor heartsSatur, Christopher Michael Raymond January 1996 (has links)
No description available.
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TSG6 : expression and influence on the stability of the extracellular matrix in joint tissuesHowat, Sarah Lamont Telfer January 2000 (has links)
No description available.
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MECHANISMS UNDERLYING REGIOSELECTIVE ACUTE TUBULAR NECROSIS OF RENAL PROXIMAL TUBULAR SEGMENTS.RUEGG, CHARLES EDWARD. January 1987 (has links)
The convoluted (CPT) and straight (SPT) portions of the renal proximal tubule are susceptible to injury by a wide variety of chemical agents. These agents often affect the CPT or SPT selectively by proposed mechanisms usually attributed to tubular concentration, blood flow delivery patterns and tubuloglomerular feedback responses within the intact kidney. The innate cellular responses to chemical exposures remain virtually unexplored. Hence, the basic goal of this research was to develop an in vitro system that was conducive to examining the innate cellular differences in susceptibility between the CPT and SPT following in vitro exposure to mercuric chloride (HgCl₂), potassium dichromate (K₂Cr₂O₇)$ or hypoxic conditions. A renal cortical slicing technique was developed for these studies to position the CPT and SPT within discrete regions of slices made perpendicular to the cortical-papillary axis. An incubation vessel that could maintain the morophological and biochemical viability of slices for at least 12 hr was also developed. The selective necrosis of CPT induced by K₂Cr₂O₇ or hypoxic exposure, and SPT induced by HgCl₂, observed in vivo was reproduced in renal cortical slices exposed in vitro. Innate cellular uptake mechanisms were then investigated since the tissue distribution of each metal was found to be most concentrated within their respective injured cell type. The transport of PAH, TEA, phosphate, sulfate, glutathione and cysteine were examined as potential mechanisms for selective accumulation of these metals. K₂Cr₂O₇ caused a dose-dependent reduction in the uptake rate of sulfate by cortical slices, while phosphate, PAH, and TEA uptake were unaffected. Although HgCl₂ has a high affinity for sulfhydryl groups its uptake as a complex to glutathione or cysteine was not enhanced. HgCl₂ also had no affect on the uptake rate of PAH or TEA even though both HgCl₂ and K₂Cr₂O₇ were able to reduce the steady state accumulation of these organic substrates.
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THE ROLE OF ENDOTOXINS IN HALOTHANE-ASSOCIATED LIVER INJURY.Lind, Richard Charles. January 1982 (has links)
No description available.
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The role of immunoglobulin receptors in the pathogenesis of rheumatoid arthritisAbrahams, Vikki Martyne January 2000 (has links)
No description available.
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Skeletal muscle damage in patients with multiple organ failureWilkinson, Ann Elizabeth January 1995 (has links)
No description available.
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Investigations into the mechanisms by which fats modulate the inflammatory response to cytokinesClamp, Alan January 1994 (has links)
No description available.
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Growth factor modulation of cytokine-mediated cell death and Fas expression in insulin-containing cellsHarrison, Moira Joan January 2000 (has links)
No description available.
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Induction and regulation of epidermal cytokinesFlint, Melanie Sarah January 1999 (has links)
No description available.
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Individual variation in the TNF response to malariaColeman, Emma Elizabeth January 1996 (has links)
No description available.
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