This diploma thesis deals with the technological process of production of a short reconstruction nail, which is used in fractures of the femoral neck. It is located between the hip joint and the femur. The work deals with the analysis of the problems from the point of view of medicine, developmental stages of the implant, materials used for the production of reconstruction nails and a description of individual technologies of nail production.

The presented Master’s Thesis aims at determining stress and strain analysis of femur with fracture fixed by intramedullary nail and cerclage cable. The one of the goals of this work was create computational model which will be able simulate problem. Computational model consist of model of femur , it’s geometry was created on basis of CT data, than there was created model of intramedullary nail and cerclage cable on a basis of real objects. In this work was created simply model of femur with the same material features and characteristic proportions as analyzed model of femur. On this model was investigated direct impact of cerclage cables on deformation, respectively displacement in a surroundings of femoral fracture. On a final model were applied the real loads conditions. Preload in a cerclage cable was simulated by cooling down to a temperature from analytical calculation. Concluding analysis was powered by Finite Element Method (FEM) applied in system ANSYS Workbench 14.5 . Due to a results of analysis, we could say that using cerclage cables in combination with intramedullary nail is an effective way for healing femoral shaft fractures.

Microcirculation plays an essential and functional role in the human body and reflects people’s physical status with microscopic detail. For peripheral microcirculation, nail-fold microscopy is a convenient and non-invasive tool since the capillaries in the nail-fold are well arranged and parallel to the skin, which is advantageous for microscopic visualization. Further, nail-fold capillaroscopy information is widely useful. In diagnosis, various diseases such as systemic lupus erythematosus and cardiac diseases can be detected and predicted at an early stage with capillaroscopic patterns and capillary blood velocity. For medical experiments, capillaroscopic information can be used to monitor drug effects and other medical treatments. Though nail-fold capillaroscopy is of significant convenience, it is not widely used. Currently, there is no commercial product with those functions due to the limitations of the equipment, such as microscope resolution and lens magnification. Besides, there is no concrete standard for measurement procedures or objective rules for quantitive data analysis. This thesis proposes a reliable system estimating nail-fold capillary blood flow velocity. It is tested and applied to the microscope from Optilia. In this work, various image and video processing methods are discussed in detail and tested in practice. Taking computational load and equipment limitations into consideration, the system applies frame enhancement and video stabilization. It uses dual-window and correlation methods to estimate the velocity of red blood cells in nail-fold capillaries. In order to test the reliability of the system, the obtained results are compared with the outcome of direct observation. It turns out that the chosen methods employed in the system provide rational results within 5 pixel bias.

Sammanfattning: This study aims to examine how cosmetic products recyclingand markings look like in Sweden. Thestudy used two methods where the first one was a visualresearch done through an externalmonitoring of ten different nail polishes where recyclingmarkings and other markings have been infocus. Then, five products that have similar properties(content, recycling, marking) as nail polishhave been analyzed to compare with the polish. Thesecond part of the method consists of aquantitative web survey to find out what nail polishconsumers' consumption looks like, how muchthey know about recycling and markings on nail polish,and how they think a nail polish bottle affectsthe environment.Results and analysis show that cosmetics/nail polishconsumers don't know much about nail polishmarkings. They know that nail polish is bad for theenvironment, but not why it is bad. This thereforeshows that the visual communication on the nail polishbottle is not sufficient and needs to be betterthrough design. It requires a circular design thatmakes conscious decisions early in the process toprevent the release of hazardous chemicals, miscommunicationregarding the recycling of packagingand clearer markings on the nail polish bottle.This study is based on the UN's global goals: 12-Responsible Consumption and Production, morespecifically 12.4- Responsible Management of Chemicalsand Waste and 13- Climate Action (UNglobal goals, 2020).

Penetrating brain injury resulting from nail-gun use is a well-characterized entity, one that is increasing in frequency as nail guns become more powerful and more readily available to the public. We present a case and offer management strategies for a 50-year-old male with two intracranial penetrating nail gun injuries. Nail gun brain injuries are commonly intentionally self-inflicted. Suicide should be considered when straight nails cause wounds to the chest, head, or abdomen. The primary preoperative concern is formation of a traumatic pseudoaneurism, which prompts both preoperative and follow-up cerebral angiography. Surgery for combined intracranial and extracranial injury may require the collaborative expertise of colleagues from the fields of ophthalmology, otolaryngology, and oral maxillofacial surgery. A rational management strategy should permit these patients to be discharged with no additional injury.

No / Keratinous tissues such as nail, hair, horn, scales and feather have been used as a source of DNA for over 20 years. Particular benefits of such tissues include the ease with which they can be sampled, the relative stability of DNA in such tissues once sampled, and, in the context of ancient genetic analyses, the fact that sampling generally causes minimal visual damage to valuable specimens. Even when freshly sampled, however, the DNA quantity and quality in the fully keratinized parts of such tissues is extremely poor in comparison to other tissues such as blood and muscle – although little systematic research has been undertaken to characterize how such degradation may relate to sample source. In this review paper we present the current understanding of the quality and limitations of DNA in two key keratinous tissues, nail and hair. The findings indicate that although some fragments of nuclear and mitochondrial DNA appear to be present in almost all hair and nail samples, the quality of DNA, both in quantity and length of amplifiable DNA fragments, vary considerably not just by species, but by individual, and even within individual between hair types.

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Civil two floors building serving as a base for athletes with further use for offices, cafe-bar, a fitness center and billiards club. The building is being designed in Jihlava in the area of football pitches with athletic oval. The building is situated near the cinema, children's playground and the Zoological Garden in Jihlava. Built-up land area is 2006 m2. The maximum capacity of the building is 418 persons and 430 capacity of grandstands. The building is constructed of ceramic bricks Porotherm. The roof construction is made of wooden trusses with a slope of three degrees. The draft of the object emphasizes the building layout, fire safety and energy savings.

The final thesis is focused on a new building of School of arts in Valašské Meziříčí. The object has three floors, it has a basement and two above-ground floors witch a flat roof. A loadbearing structure is made of skeleton - reinforced concrete monolithic columns and reinforced concrete monolithic floor slabs. Filling masonry is made of ceramic tiles. Object has thermal insulation by mineral wool. Detailed solution of final thesis deals with the solution of main building School of arts, where are the schoolrooms and technical facilities. In the other parts of the object are a staff facilities, multipurpose hall, café and underground garage.