Dans cette thèse, nous étudions le vaste domaine des neurosciences à travers des outils théoriques, numériques et expérimentaux. Nous étudions comment les modèles à taux de décharge peuvent être utilisés pour capturer différents phénomènes observés dans le cerveau. Nous étudions les régimes dynamiques des réseaux couplés de neurones excitateurs (E) et inhibiteurs (I): Nous utilisons une description fournie par un modèle à taux de décharge et la comparons avec les simulations numériques des réseaux de neurones à potentiel d'action décrits par le modèle EIF. Nous nous concentrons sur le régime où le réseau EI présente des oscillations, puis nous couplons deux de ces réseaux oscillants pour étudier la dynamique résultante. La description des différents régimes pour le cas de deux populations est utile pour comprendre la synchronisation d'une chaine de modules E-I et la propagation d'ondes observées dans le cerveau. Nous examinons également les modèles à taux de décharge pour décrire l'adaptation sensorielle: Nous proposons un modèle de ce type pour décrire l'illusion du mouvement consécutif («motion after effect», (MAE)) dans la larve du poisson zèbre. Nous comparons le modèle à taux de décharge avec des données neuronales et comportementales nouvelles. / In this thesis, we investigate the vast field of neuroscience through theoretical, numerical and experimental tools. We study how rate models can be used to capture various phenomena observed in the brain. We study the dynamical regimes of coupled networks of excitatory (E) and inhibitory neurons (I) using a rate model description and compare with numerical simulations of networks of neurons described by the EIF model. We focus on the regime where the EI network exhibits oscillations and then couple two of these oscillating networks to study the resulting dynamics. The description of the different regimes for the case of two populations is helpful to understand the synchronization of a chain of E-I modules and propagation of waves observed in the brain. We also look at rate models of sensory adaptation. We propose one such model to describe the illusion of motion after effect in the zebrafish larva. We compare this rate model with newly obtained behavioural and neuronal data in the zebrafish larva.

This thesis investigates the functionality of the units used in connectionist Artificial Intelligence systems. Artificial Neural Networks form the foundation of the research and their units, Artificial Neurons, are first compared with alternative models. This initial work is mainly in the spatial-domain and introduces a new neural model, termed a Taylor Series neuron. This is designed to be flexible enough to assume most mathematical functions. The unit is based on Power Series theory and a specifically implemented Taylor Series neuron is demonstrated. These neurons are of particular usefulness in evolutionary networks as they allow the complexity to increase without adding units. Training is achieved via various traditiona and derived methods based on the Delta Rule, Backpropagation, Genetic Algorithms and associated evolutionary techniques. This new neural unit has been presented as a controllable and more highly functional alternative to previous models. The work on the Taylor Series neuron moved into time-domain behaviour and through the investigation of neural oscillators led to an examination of single-celled intelligence from which the later work developed. Connectionist approaches to Artificial Intelligence are almost always based on Artificial Neural Networks. However, another route towards Parallel Distributed Processing was introduced. This was inspired by the intelligence displayed by single-celled creatures called Protoctists (Protists). A new system based on networks of interacting proteins was introduced. These networks were tested in pattern-recognition and control tasks in the time-domain and proved more flexible than most neuron models. They were trained using a Genetic Algorithm and a derived Backpropagation Algorithm. Termed "Artificial BioChemical Networks" (ABN) they have been presented as an alternative approach to connectionist systems.