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No description available.

No description available.

No description available.

No description available.

No description available.

<p> We propose a data-driven estimation algorithm in survival mixture model. The objective of this study is to provide an alternative fitting procedure to the conventional EM algorithm. The EM algorithm is the classical ML fitting of the parametric mixture model. If the initial values for the EM algorithm are not properly chosen, the maximizers might be local or divergent. Traditionally, initial values are given manually according to experience or a gridpoint search. This is a heavy burden for a high-dimensional data sets. Also, specifying the ranges of parameters for a grid-point search is difficult. To avoid the specification of initial values, we employ the random partition. Then, improvement of fitting is adjusted according to model specification. This process is repeated a large number of times, so it is computer intensive. The large repetitions makes the solution more likely to be the global maximizer, and it is driven purely by the data. We conduct a simulation study for three cases of two-component Log-Normal, two-component Weibull, and two-component Log-Normal and Wei bull, in order to illustrate the effectiveness of the proposed algorithm. Finally, we apply our algorithm to a breast cancer study data which follows a cure model. The program is written in R. It calls existing R functions, so it is flexible to use in regression situations where model formula must be specified. </p> / Thesis / Master of Science (MSc)

An iterative solution to the problem of blind image deconvolution is presented whereby a previous image estimate is explicitly used in the new image estimation process. The previous image is pre-filtered using an adaptive, non-parametric stabilizing function that is updated based on a current error estimate. This function is experimentally shown to dramatically benefit the convergence rate for the a priori restoration case. Noise propagation from one iteration to the next is reduced by the use of a second, regularizing operator, resulting in a hybrid iteration technique. Further, error terms are developed that shed new light on the error propagation properties of this method and others by quantifying the extent of noise and regularization error propagation. Optimal non-parametric, frequency adaptive stabilizing and regularization functions are then derived based on this error analysis. / Thesis / Master of Engineering (ME)

Rumination consists of voluntary regurgitation of partially digested food, followed by chewing and re-swallowing or expulsion of regurgitated stomach contents (DM-ID2). Little research has systematically analyzed the differential effects of type or quantity of food on rumination across extended observations. This analysis demonstrated that certain (isolated) foods may differentially affect the rate of rumination. Furthermore, patterns of responding and manipulations of quantity may provide evidence for naturally occurring contingencies of punishment for the rumination of particular foods. These results may provide an avenue for minimally invasive, sustainable treatment for individuals with severe and chronic rumination.