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Sex differences in psychosis: normal or pathological?Spauwen, Janneke, Krabbendam, Lydia, Lieb, Roselind, Wittchen, Hans-Ulrich, van Os, Jim 08 April 2013 (has links) (PDF)
Background: Schizophrenia first appears in adolescence, in boys at an earlier age than girls. The interpretation of this key epidemiological finding crucially depends on whether similar age-related sex differences exist in the expression of associated, subclinical psychosis-like experiences.
Methods: Findings are based on a population sample of 2548 adolescents and young adults aged 17–28. Subjects were assessed with the core psychosis sections on delusions and hallucinations of the Munich- Composite International Diagnostic Interview.
Results: The risk of subclinical psychotic experiences was significantly higher for males in the younger half of the cohort (17–21 years), but similar in the older half (22–28 years).
Conclusions: These findings suggest that normal maturational changes in adolescence with differential age of onset in boys and girls cause the expression of psychosis, the extreme of which is schizophrenia.
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Sex differences in psychosis: normal or pathological?Spauwen, Janneke, Krabbendam, Lydia, Lieb, Roselind, Wittchen, Hans-Ulrich, van Os, Jim January 2003 (has links)
Background: Schizophrenia first appears in adolescence, in boys at an earlier age than girls. The interpretation of this key epidemiological finding crucially depends on whether similar age-related sex differences exist in the expression of associated, subclinical psychosis-like experiences.
Methods: Findings are based on a population sample of 2548 adolescents and young adults aged 17–28. Subjects were assessed with the core psychosis sections on delusions and hallucinations of the Munich- Composite International Diagnostic Interview.
Results: The risk of subclinical psychotic experiences was significantly higher for males in the younger half of the cohort (17–21 years), but similar in the older half (22–28 years).
Conclusions: These findings suggest that normal maturational changes in adolescence with differential age of onset in boys and girls cause the expression of psychosis, the extreme of which is schizophrenia.
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