The principal aim has been to investigate the contemporary role and importance of edible wild plants in the diets of women in different agro-ecological regions of Vietnam. Field studies were undertaken in four villages in the Mekong Delta (MD) and the Central Highlands (CH) in 1995-1999. Data collection included rapid appraisal techniques, botanical identification, dietary assessments (7-day food frequency recall), anthropometry, blood sampling (haemoglobin, serum ferritin, serum retinol and C-reactive protein) and analysis of vegetable samples (dry matter, selected minerals and vitamins, tannins and phytic acid). A food variety analysis was used to test the adequacy of diets. The uses of over 90 wild plant species were documented, many with multiple functions as foods, medicines and livestock feeds. In the dietary assessment 29 species were reported. Most women used a combination of home produced, commercial and wild vegetables. A high 72 and 43% respectively of the vegetables consumed in the MD and CH sites were gathered (rainy season). They contributed significantly to micronutrient intakes, especially vitamin A, calcium, vitamin C and folate. They added considerably to food diversity and women with the most diverse diets had relatively adequate nutrient intakes. The species used and importance of wild plants varied considerably with region, season and ethnicity. The main conclusions are that edible wild plants continue to make important contributions to the nutrient intakes of women. If this is neglected in diet assessments our understanding of the overall dietary adequacy may be misinterpreted and much valuable knowledge of traditional food diversification may be lost. A food variety analysis can be a useful tool in identifying groups with inadequate diets. The dual role of many species as dietary components and in preventive health care deserves greater attention.

Background Transthyretin amyloid (ATTR) amyloidosis is a systemic disorder caused by amyloid deposits formed by misfolded transthyretin (TTR) monomers. Two main forms exist – wild-type and hereditary ATTR amyloidosis, the latter associated with TTR gene mutations. Wild-type ATTR amyloidosis has a late onset and primarily cardiac manifestations, whereas hereditary ATTR amyloidosis is a rare autosomal dominant condition with a considerable phenotypic diversity. Both disorders are present all over the world, but endemic areas of the hereditary form are found in Sweden, Portugal, Brazil and Japan. Gastrointestinal (GI) complications are common in hereditary ATTR amyloidosis and play an important role in the patients’ morbidity and mortality. Malfunction of the autonomic and enteric nervous systems has been proposed to contribute to the GI disturbances, but the underlying mechanisms have not been fully elucidated. The aims of this thesis were to assess the prevalence of GI disturbances for different subtypes of ATTR amyloidosis, to further explore the mechanisms behind these disturbances, and to evaluate the outcome of the patients’ GI function after liver transplantation, which currently is the standard treatment for hereditary ATTR amyloidosis. Methods The Transthyretin Amyloidosis Outcomes Survey (THAOS) is the first global, multicenter, longitudinal, observational survey that collects data on patients with ATTR amyloidosis. THAOS enrollment data were used to assess the prevalence of GI symptoms and to evaluate their impact on nutritional status (mBMI) and health-related quality of life (EQ-5D Index Score). Data from routine investigations of heart-rate variability and cardio-vascular response to tilt tests were utilized to evaluate the impact of autonomic neuropathy on the scintigraphically measured gastric emptying half-times in Swedish patients with hereditary ATTR amyloidosis. Gastric wall autopsy specimens from Japanese patients with hereditary ATTR amyloidosis and Japanese non-amyloidosis controls were analyzed with immunohistochemistry and computerized image analysis to assess the densities of interstitial cells of Cajal (ICC) and nervous tissue. Data from gastric emptying scintigraphies and validated questionnaires were used to evaluate the outcome of Swedish patients’ GI function after liver transplantation for hereditary ATTR amyloidosis. Results Sixty-three percent of the patients with TTR mutations and 15 % of those with wild-type ATTR amyloidosis reported GI symptoms at enrollment into THAOS. Subsequent analyses focused on patients with TTR mutations and, among them, unintentional weight loss was the most frequent symptom (32 %) followed by early satiety (26 %). Early-onset patients (<50 years of age) reported GI symptoms more frequently than late-onset cases (70 % vs. 50 %, p <0.01), and GI symptoms were more common in patients with the V30M mutation than in those with non-V30M mutations (69 % vs. 56 %, p <0.01). Both upper and lower GI symptoms were significant negative predictors of nutritional status and health-related quality of life (p <0.01 for both). Weak but significant correlations were found between gastric emptying half-times and the function of both the sympathetic (rs = -0.4, p <0.01) and parasympathetic (rs = -0.3, p <0.01) nervous systems. The densities of c-Kit-immunoreactive ICC were significantly lower in the circular (median density 0.0 vs. 2.6, p <0.01) and longitudinal (median density 0.0 vs. 1.8, p <0.01) muscle layers of the gastric wall in patients compared to controls. Yet, no significant differences in protein gene product 9.5-immunoreactive nervous cells were found between patients and controls either in the circular (median density 3.0 vs. 6.8, p = 0.17) or longitudinal (median density 1.4 vs. 2.5, p = 0.10) muscle layers. Lastly, the patients’ GI symptoms scores had increased slightly from before liver transplantation to the follow-ups performed in median two and nine years after transplantation (median score 7 vs. 10 vs. 13, p <0.01). However, their gastric emptying half-times (median half-time 137 vs. 132 vs. 125 min, p = 0.52) and nutritional statuses (median mBMI 975 vs. 991 vs. 973, p = 0.75) were maintained at follow-ups in median two and five years after transplantation. Conclusion GI disturbances are common in hereditary ATTR amyloidosis and have a negative impact on the patients’ nutritional status and health-related quality of life. Fortunately, a liver transplantation appears to halt the progressive GI involvement of the disease, although the patients’ GI symptoms tend to increase after transplantation. An autonomic neuropathy and a depletion of gastrointestinal ICC seem to contribute to the GI disturbances, but additional factors must be involved.

Submitted by Claudia Rocha (claudia.rocha@udesc.br) on 2018-03-21T14:23:46Z No. of bitstreams: 1 PGCA17MA228.pdf: 726282 bytes, checksum: 40f271b726c358d9c09eb5ec50c81604 (MD5) / Made available in DSpace on 2018-03-21T14:23:46Z (GMT). No. of bitstreams: 1 PGCA17MA228.pdf: 726282 bytes, checksum: 40f271b726c358d9c09eb5ec50c81604 (MD5) Previous issue date: 2017-06-22 / Capes / Nitrogen (N) participates in several metabolic processes in the plant and is directly related to the accumulation of dry matter of the pasture, thus reflecting increases in the overall productivity of the system. In this sense, the Ncritical (lower concentration of N for a given species to perform its maximum growth potential) in multispecies pastures may change depending on the species that compose it. The objective of this work was to evaluate the NNI (Nitrogen Nutrition Index) in three perennial winter grasses (oatgrass - Arrhenatherum elatius, cocksfoot - Dactylis glomerata - and tall fescue - Festuca arundinacea) cultivated as monocultures or intercropped throughout the four seasons of the year. The experimental area was located in Lages, SC, containing 12 paddocks of 45 m2 each where the four treatments (the three pure cultivated species and the mixture) were distributed through a completely randomized design with three replicates. The cut height at each treatment was determined by the time the swards intercept 95% of the incident light during the vegetative stage of the pastures, being lowered by 50% of this height. Fertilization was carried out with the equivalent of 50 kg / N / ha every 40 days, totaling 450 kg of N / ha / year. The forage mass was determined in pre-cut, and thus evaluated the N contents in the forage mass and the N contents in the 10 cm of the upper part of the canopy for the species pure and individually for each species in the consortium. The Ncritical was estimated by the equation: Ncritical = 4,8 x W-0,32, where W is the mass of forage above the level of the soil. A second experiment was carried out with the objective of evaluating the effect of the management adopted on the N dilution curve, in which two methods were performed to determine the N dilution curve, one performed with the management adopted in the experiment (starting from a residual height of 10 cm) and another with the management proposed by the literature starting from the ground level. Statistical analyzes were performed using the MIXED procedure of the SAS statistical program (version 9.02) with 5% significance. Regression analyzes were performed using the SigmaPlot(R) statistical package. In general, the NNI actually observed did not reach the critical values (Experiment I), however, when corrected (disregarded the percentage of dead material in the sample) NNIs were satisfactory for all species at all times. Throughout the manuscript inferences are discussed on the ways to evaluate the INN in perennial pastures under lenient grazing, due to the changes in the dilution of nitrogen, due to the high percentage of dead material at the beginning of pasture growth. The height control was important in the coexistence of the species in the consortium, since it allowed the entrance of luminosity, decisive factor in the absorption of N / O nitrogênio (N) participa de diversos processos metabólicos na planta e está diretamente relacionado com o acúmulo de matéria seca do pasto, refletindo, assim, em aumentos em produtividade global do sistema. Neste sentido, o Ncrítico (menor concentração de N para que uma determinada espécie desempenhe seu máximo potencial de crescimento) em pastagens multiespecíficas pode mudar em função das espécies que o compõem. Dessa forma, o objetivo desse trabalho foi avaliar o INN (índice de nutrição nitrogenada) em três espécies perenes de inverno (Aveia perene - Arrhenatherum elatius-, Dáctilis - Dactylis glomerata- e Festuca - Festuca arundinacea) cultivadas puras e em consórcio ao longo das quatro estações do ano. A área experimental foi implantada em Lages, SC, contendo 12 piquetes de 45 m2 cada onde foram distribuídos os quatro tratamentos (as três espécies cultivadas puras e o consórcio entre elas) por meio de um delineamento inteiramente casualizado com três repetições. A altura de corte em cada tratamento foi determinada pelo momento em que os mesmos interceptarem 95% da luz incidente durante o estádio de desenvolvimento vegetativo dos pastos, sendo rebaixados em 50% desta altura. As adubações foram realizadas com o equivalente a 50 kg/N/ha a cada 40 dias, totalizando 450 kg de N/ha/ano. Foi determinada a massa de forragem em pré-corte, e, assim avaliados os teores de N na massa de forragem e os teores de N nos 10 cm da parte superior do dossel para as espécies puras e individualmente para cada espécie no consórcio. O Ncrítico foi estimado pela equação: Ncrítico = 4,8 x W-0,32, onde W é a massa de forragem acima do nível do solo. Foi realizado um segundo experimento, com o objetivo de avaliar o efeito do manejo adotado na curva de diluição do N, no qual foram executados dois métodos para determinar a de curva de diluição do N, uma realizada com o manejo adotado no experimento (partindo de uma altura residual de 10 cm) e outra com o manejo proposto pela literatura partindo do nível do solo. As análises estatísticas foram realizadas por meio do procedimento MIXED do programa estatístico SAS (versão 9.02) com 5% de significância. As análises de regressão foram realizadas utilizando-se o pacote estatístico SigmaPlot (R). De modo geral, os INN efetivamente observados não alcançaram os valores críticos (Experimento I), no entanto, quando corrigidos (desconsiderados os porcentuais de material morto da amostra) os INN foram satisfatórios para todas as espécies em todas as épocas. Ao longo do manuscrito inferências são discutidas sobre as formas de se avaliar o INN em pastos perenes sob pastejo leniente, devido às alterações na diluição do nitrogênio, consequência da alta porcentagem de material morto no início do crescimento dos pastos. O controle de altura foi importante na coexistência das espécies no consórcio, pois permitiu a entrada de luminosidade, fator decisivo na absorção de N

Made available in DSpace on 2016-02-26T12:59:45Z (GMT). No. of bitstreams: 1 EdimilsonVolpe.pdf: 773343 bytes, checksum: 8d83aef1e120860b72ba0d2d02ffaf35 (MD5) Previous issue date: 2006-11-06 / It was carried out an experiment in purpose to test four levels of soil base saturation (20%, 40%, 60% and 80%), four rates of phosphorus (0, 80, 160 and 240 kg ha-1 of P2O5) and four rates of nitrogen (0, 100, 200 and 300 kg ha-1) during the phase of Panicum Maximum cv Massai implant, in Oxisol of Brazilian Cerrado, in Campo Grande, MS. The experimental design used was randomized blocks in fractionated fatorial type (1/2)43, with 32 treatments and two replications. Two cuts along 200 days were done. The evaluated aspects were green dry mass (GDM) accumulation, soil fertility changes, concentration of macronutrients in diagnostic leaves, crude protein (CP) rate and in vitro organic matter digestibility (IVOMD). It was verified significant effect of the phosphorus (P) fertilization (p<0,05) and of the V (0,10>p<0,20) in the GDM in two cuts sum. The nitrogen (N) didn t present signiticative effect in GDM accumulation. The higher dose for P for higher physical production was 237 kg ha-1 and the economical dose was 185 kg ha-1, both in soil base saturation (V) of 39% in the soil. P. maximun cv Massai GDM accumulation in this phase was 9.441 and 9.260 kg ha-1 in maximum physical and economical dose, respectively. All soil chemical characteritics studied (P, Ca, Mg, Al, m and V) presented significative variations in relation to the treatments. The V presented below the liming target. The soil P availability by the Mehlich 1 extractor, in GDM maximum production and P2O5 maximum rate used, didn t reached the expected disponibility soil for grass forage studied. The estimated concentration of nutrients (N, P, Ca, Ms and S) in diagnostic leaves presented that, in zero dose of N and P and in 20% target V , only P was limiting. All nutrients presented significative variations in relation to the treatments. It was revified in morphological components of grass high percentage of lamina leaves (77,50%) in GDM. It was revified in the nutritive value avaluation suitable in vitro organic matter digestibility (IVOMD) and crude protein (CP) rate in GDM lamina leaves. IVOMD and CP increased significantly with N fertilization and increment of V / Um experimento foi realizado com o objetivo de testar quatro níveis de saturação por bases (20%, 40%, 60% e 80%), quatro doses de fósforo (0, 80, 160 e 240 kg ha-1 de P2O5) e quatro doses de nitrogênio (0, 100, 200 e 300 kg ha-1), na fase de estabelecimento de Panicum maximum cv Massai, em LATOSSOLO VERMELHO Distrófico de Cerrado, em Campo Grande, MS. O delineamento experimental foi em blocos casualizados no esquema fatorial fracionário (1/2)43, com 32 tratamentos e duas repetições. Foram realizados dois cortes em aproximadamente 200 dias. Os aspectos avaliados foram produção de forragem, variações na fertilidade do solo, estado nutricional das plantas e características do valor nutritivo (VN) da forragem. Foi verificado efeito significativo da adubação fosfatada (p<0,05) e da saturação por bases (0,10>P<0,20) no acúmulo de massa seca verde (MSV), na soma de dois cortes. O nitrogênio (N) não apresentou efeito significativo no acúmulo de forragem. A dose de maior produção agronômica para o fósforo (P) foi de 237 kg ha-1 de P2O5 e a dose econômica foi de 185 kg ha-1, ambas sob saturação por bases (V) no solo de 39%. O acúmulo de MSV do capim-Massai foi de 9.441 e 9.260 kg ha-1 nas doses de máxima eficiência agronômica e econômica, respectivamente. Todos as características químicas do solo estudadas (P, Ca, Mg, Al, m e V) apresentaram variações significativas em função dos tratamentos. A V no solo apresentou valor inferior ao pretendido com a calagem. O teor de P no solo, extraído por Mehlich 1, no ponto de máxima produção de MSV e na dose máxima P2O5, não alcançou o teor no solo recomendado para a forrageira em estudo. A concentração estimada de macronutrientes (N, P, Ca, Mg e S) nas folhas diagnósticas da planta mostrou que, no tratamento de dose zero de N e P e 20% de V, apenas o P era limitante. Todos os macronutrientes estudados responderam significativamente aos tratamentos. Nas avaliações dos componentes morfológicos da gramínea verificou-se alta porcentagem de folhas (77,50%) na MSV. Nas características do VN verificou-se valores adequados da digestibilidade in vitro de matéria orgânica (DIVMO) e do teor de proteína bruta (PB) na fração folhas da MSV. A DIVMO e a PB aumentaram significativamente com a adubação nitrogenada e com o aumento da V

A doença Inflamatória Intestinal (DII) é uma desordem caracterizada pela inflamação crônica do trato gastrointestinal. Os dois principais tipos de DII são a Retocolite Ulcerativa (RCU) e a Doença de Crohn (DC) e ambas cursam com importantes alterações no estado nutricional (EN). O objetivo deste estudo foi identificar as diferenças na composição corporal entre pacientes com DC, RCU e indivíduos saudáveis, além de comparar o estado nutricional dos três grupos de pacientes, ajustando para fatores que podem interferir no EN, como o uso atual de corticosteróides, a atividade física, a atividade de doença, a idade e o sexo. Foi realizado um estudo transversal que incluiu 101 pacientes com DII (50 com DC e 51 com RCU) e 35 indivíduos saudáveis, selecionados no Ambulatório do Hospital Universitário Pedro Ernesto (HUPE) da Universidade do Estado do Rio de Janeiro (UERJ). Foram colhidas informações sócio-demográficas e pessoais, tais como: prática de atividade física, tabagismo, doenças pregressas e procedimentos cirúrgicos prévios. Outras informações necessárias à pesquisa foram coletadas em prontuário médico. A avaliação antropométrica foi realizada por meio das seguintes medidas: peso corporal; altura; circunferências do braço, da cintura (CC) e do quadril; dobras cutâneas do tríceps, subescápula, supra-ilíaca e da coxa; e circunferência muscular do braço (CMB). A análise da composição corporal foi realizada por meio da bioimpedância elétrica (BIA), utilizando-se o aparelho Biodynamics modelo 450. As variáveis laboratoriais analisadas foram: glicose, hemograma completo, perfil lipídico, proteínas totais, albumina, globulina, velocidade de hemossedimentação e proteína C reativa. O peso, o índice de massa corporal, a CC e o percentual de gordura corporal calculado a partir da aferição das dobras cutâneas, foram menores nos pacientes com DC, quando comparados aos indivíduos saudáveis e/ou aos pacientes com RCU. A CMB foi menor nos pacientes com DC e RCU quando comparados aos indivíduos saudáveis, porém sem apresentar diferenças entre os dois grupos de pacientes. Por BIA, verificou-se que os pacientes com DC apresentaram valores de massa magra, massa celular corpórea, massa extracelular, água corporal total e água extracelular menores quando comparados aos indivíduos saudáveis. Os níveis séricos de colesterol total, proteínas totais e albumina, e a contagem total de hemácias foram menores nos indivíduos com DC quando comparados aos indivíduos do grupo controle e/ou aos indivíduos do grupo da RCU. Os pacientes com RCU exibem composição corporal semelhante à da população saudável. Em contraposição, os pacientes com DC apresentam EN amplamente comprometido com depleção de gordura corporal e massa magra em relação aos demais indivíduos / Inflammatory Bowel Disease (IBD) is a disorder characterized by diffuse inflammation of the gastrointestinal tract. The two main types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), both coursing with important changes in nutritional status (NS). The objective of this study was to identify differences in body composition between patients with CD, UC, and healthy subjects and to compare the NS of these three groups of patients, adjusting for factors that can interfere in NS such as current use of corticosteroids, physical activity, disease activity, age and sex. It was conducted a cross-sectional study which included 101 patients with IBD (50 with CD and 51 with UC) and 35 healthy subjects, selected at the Ambulatory of Pedro Ernesto University Hospital (HUPE) of the Rio de Janeiro State University (UERJ). Socio-demographic and personal information such as physical activity, smoking, prior diseases and previous surgical procedures were collected. Other necessary information for the research were collected from medical records. The anthropometric evaluation was carried out through the following measures: body weight; height; mid-arm, waist and hip circumferences; skinfold thickness of the triceps, subscapular, suprailiac, and thigh; and mid-arm muscle circumference (MAMC). The body composition analysis was performed by bioelectrical impedance (BIA) using the equipment Biodynamics model 450. The laboratory variables analyzed, included: glucose, complete blood count, lipid profile, total protein, albumin, globulin, erythrocyte sedimentation rate, and C-reactive protein. Weight, body mass index, waist circumference, and percentage body fat calculated from skinfold measurements were lower in CD patients compared to healthy subjects and/or the patients with UC. The MAMC was lower in patients with CD and UC compared to healthy subjects, but without showing differences between the two groups of patients. Through BIA, it was found that CD patients had values of lean body mass, body cell mass, extracellular mass, total body water, and extracellular water smaller when compared to healthy subjects. Seric levels of total cholesterol, total protein, and albumin, as well as red blood cell count and relative count of lymphocytes were lower in the individuals with CD than the individuals of the control group and/or the patients with UC. Patients with UC exhibit body composition similar to that of the healthy population. In contrast, CD patients have widely NS committed with depletion of body fat and lean mass in relation to other individuals.

A doença Inflamatória Intestinal (DII) é uma desordem caracterizada pela inflamação crônica do trato gastrointestinal. Os dois principais tipos de DII são a Retocolite Ulcerativa (RCU) e a Doença de Crohn (DC) e ambas cursam com importantes alterações no estado nutricional (EN). O objetivo deste estudo foi identificar as diferenças na composição corporal entre pacientes com DC, RCU e indivíduos saudáveis, além de comparar o estado nutricional dos três grupos de pacientes, ajustando para fatores que podem interferir no EN, como o uso atual de corticosteróides, a atividade física, a atividade de doença, a idade e o sexo. Foi realizado um estudo transversal que incluiu 101 pacientes com DII (50 com DC e 51 com RCU) e 35 indivíduos saudáveis, selecionados no Ambulatório do Hospital Universitário Pedro Ernesto (HUPE) da Universidade do Estado do Rio de Janeiro (UERJ). Foram colhidas informações sócio-demográficas e pessoais, tais como: prática de atividade física, tabagismo, doenças pregressas e procedimentos cirúrgicos prévios. Outras informações necessárias à pesquisa foram coletadas em prontuário médico. A avaliação antropométrica foi realizada por meio das seguintes medidas: peso corporal; altura; circunferências do braço, da cintura (CC) e do quadril; dobras cutâneas do tríceps, subescápula, supra-ilíaca e da coxa; e circunferência muscular do braço (CMB). A análise da composição corporal foi realizada por meio da bioimpedância elétrica (BIA), utilizando-se o aparelho Biodynamics modelo 450. As variáveis laboratoriais analisadas foram: glicose, hemograma completo, perfil lipídico, proteínas totais, albumina, globulina, velocidade de hemossedimentação e proteína C reativa. O peso, o índice de massa corporal, a CC e o percentual de gordura corporal calculado a partir da aferição das dobras cutâneas, foram menores nos pacientes com DC, quando comparados aos indivíduos saudáveis e/ou aos pacientes com RCU. A CMB foi menor nos pacientes com DC e RCU quando comparados aos indivíduos saudáveis, porém sem apresentar diferenças entre os dois grupos de pacientes. Por BIA, verificou-se que os pacientes com DC apresentaram valores de massa magra, massa celular corpórea, massa extracelular, água corporal total e água extracelular menores quando comparados aos indivíduos saudáveis. Os níveis séricos de colesterol total, proteínas totais e albumina, e a contagem total de hemácias foram menores nos indivíduos com DC quando comparados aos indivíduos do grupo controle e/ou aos indivíduos do grupo da RCU. Os pacientes com RCU exibem composição corporal semelhante à da população saudável. Em contraposição, os pacientes com DC apresentam EN amplamente comprometido com depleção de gordura corporal e massa magra em relação aos demais indivíduos / Inflammatory Bowel Disease (IBD) is a disorder characterized by diffuse inflammation of the gastrointestinal tract. The two main types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), both coursing with important changes in nutritional status (NS). The objective of this study was to identify differences in body composition between patients with CD, UC, and healthy subjects and to compare the NS of these three groups of patients, adjusting for factors that can interfere in NS such as current use of corticosteroids, physical activity, disease activity, age and sex. It was conducted a cross-sectional study which included 101 patients with IBD (50 with CD and 51 with UC) and 35 healthy subjects, selected at the Ambulatory of Pedro Ernesto University Hospital (HUPE) of the Rio de Janeiro State University (UERJ). Socio-demographic and personal information such as physical activity, smoking, prior diseases and previous surgical procedures were collected. Other necessary information for the research were collected from medical records. The anthropometric evaluation was carried out through the following measures: body weight; height; mid-arm, waist and hip circumferences; skinfold thickness of the triceps, subscapular, suprailiac, and thigh; and mid-arm muscle circumference (MAMC). The body composition analysis was performed by bioelectrical impedance (BIA) using the equipment Biodynamics model 450. The laboratory variables analyzed, included: glucose, complete blood count, lipid profile, total protein, albumin, globulin, erythrocyte sedimentation rate, and C-reactive protein. Weight, body mass index, waist circumference, and percentage body fat calculated from skinfold measurements were lower in CD patients compared to healthy subjects and/or the patients with UC. The MAMC was lower in patients with CD and UC compared to healthy subjects, but without showing differences between the two groups of patients. Through BIA, it was found that CD patients had values of lean body mass, body cell mass, extracellular mass, total body water, and extracellular water smaller when compared to healthy subjects. Seric levels of total cholesterol, total protein, and albumin, as well as red blood cell count and relative count of lymphocytes were lower in the individuals with CD than the individuals of the control group and/or the patients with UC. Patients with UC exhibit body composition similar to that of the healthy population. In contrast, CD patients have widely NS committed with depletion of body fat and lean mass in relation to other individuals.