Spelling suggestions: "subject:"anataxis"" "subject:"anâtaxis""
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Role of the Prefrontal Glucocorticoid Receptor in Synaptic, Neuroendocrine, and Behavioral Stress AdaptationMcKlveen, Jessica M. 05 June 2015 (has links)
No description available.
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The Role Of Gut Microbiome In 3,4 Methylene Dioxymethamphetamine (MDMA) Mediated Hyperthermia In RatsChoudhury, Sayantan Roy 22 August 2018 (has links)
No description available.
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CONSIDERATIONS FOR USING THE DYNAMIC INERTIA METHOD IN ESTIMATING RIGID BODY INERTIA PROPERTYLAZOR, DANIEL R., Jr. 06 October 2004 (has links)
No description available.
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Runout Evaluation Methods for Cylindrical, Tapered and Flat surfacesRAJMOHAN, SIDDHARTH 22 April 2008 (has links)
No description available.
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Chronic Stress, Neurotransmitter Plasticity, and Body WeightFlak, Jonathan N. January 2011 (has links)
No description available.
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Effects of Shaker Impedance and Transducer Cross-Axis Sensitivity in Frequency Response Function EstimationHassan Pour Dargah, Mahmoud 08 October 2012 (has links)
No description available.
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Missile autopilot design using a gain scheduling techniqueWhite, David Paul January 1994 (has links)
No description available.
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Neural and immune changes that occur following psychological and physical stressorsNeigh, Gretchen N. 29 September 2004 (has links)
No description available.
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THE ROLE OF DISCO IN DLL-DEPENDENT PROXIMAL DISTAL AXIS SPECIFICATION OF DROSOPHILA APPENDAGESPopo-Ola, Emmanuel 10 1900 (has links)
Distal-less (Dll) is a master regulator gene responsible for proximal-distal axis formation as well as distal appendage identity. Previous research showed that the expression of Dll is maintained through a feedback loop with Disco, a C2H2 zinc finger transcription factor. In this project I investigate recent suggestions that disco may play additional roles as a cofactor or downstream target of Dll during appendage development. I confirm previous research that the presence of Dll is sufficient to turn on disco. I found that the presence of ectopic Dll in the wing discs activates Dll subordinate genes in cells where they are not normally expressed. I again performed experiments confirming previous reports that ectopic expression of Dll in the wing tissue is sufficient to cause the appearance of ectopic legs. I then showed that when Dll is expressed ectopically in the absence of disco, there ectopic appendages similar to those formed in the presence of disco. Put together, my results suggest that disco is does not function as a cofactor or downstream target required for the development and differentiation of Drosophila ventral appendages. / Thesis / Master of Science (MSc)
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Exploring host genetic differences in gastrointestinal microbiota and homeostasis, through the production of fecal miRNAHorne, Rachael January 2018 (has links)
Research has shown that our gut microbiota confers many beneficial functions, including aiding the development of the immune system, metabolism, modulating stress reactivity and behaviour. The diverse population of the gut microbiota has been shown to be heterogeneous between individuals, with host genetic factors emerging as a contributor to gut microbiota composition. Recent work suggests that microRNA may act as a mediator of communication between the host and resident gut microbiota. Here we explore host genetic differences in gut microbiota composition and fecal miRNA profiles in two inbred mouse strains BALB/C and C57BL/6, in relation to gastrointestinal homeostasis. Furthermore, we evaluate the role of host genetics in response to perturbation of the gut microbiota using broad-spectrum antibiotic treatment. Distinct differences in the gut microbiota composition evaluated by fecal 16s rRNA gene sequencing between BALB/c and C57BL/6 mice were found with notable significant differences in genera Prevotella, Alistipes, Akkermansia and Ruminococcus. Significant host genetic differences were also observed in fecal miRNA profiles evaluated using the nCounter Nanostring platform. A BLASTn analysis was used to identify conserved fecal miRNA target regions in bacterial metagenomes, which identified numerous bacterial gene targets. Of those miRNA targets that were conserved in our dataset, 14 significant correlations were found between fecal miRNA and predicted taxa relative abundance. Treatment with broad-spectrum antibiotics for a period of 2 weeks resulted in BALB/c mice exhibiting a decrease in barrier permeability while C56BL/6 barrier permeability remained unchanged, demonstrating a host-specific physiological response to antibiotics at the gastrointestinal barrier. Differential response to antibiotics was also observed in the expression of barrier regulating genes in both host strains. Individual taxa were found to respond differentially by host strain, with Parabacteroides and Bacteroides associating with changes in barrier function. Together these findings suggest that host genetics play a role in determining the host-microbe relationship in both healthy homeostatic conditions and altered microbial conditions. / Thesis / Master of Science (MSc)
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