No description available.

Nesta pesquisa, estudamos e comparamos duas maneiras de se construir redes. O principal objetivo do nosso estudo é encontrar uma forma efetiva de se construir redes, especialmente quando temos menos observações do que variáveis. A construção das redes é realizada através da estimação do coeficiente de correlação parcial com base na estatística clássica (inverse method) e na Bayesiana (priori conjugada Normal - Wishart invertida). No presente trabalho, para resolver o problema de se ter menos observações do que variáveis, propomos uma nova metodologia, a qual chamamos correlação parcial local, que consiste em selecionar, para cada par de variáveis, as demais variáveis que apresentam maior coeficiente de correlação com o par. Aplicamos essas metodologias em dados simulados e as comparamos traçando curvas ROC. O resultado mais atrativo foi que, mesmo com custo computacional alto, usar inferência Bayesiana é melhor quando temos menos observações do que variáveis. Em outros casos, ambas abordagens apresentam resultados satisfatórios. / This research is about studying and comparing two different ways of building complex networks. The main goal of our study is to find an effective way to build networks, particularly when we have fewer observations than variables. We construct networks estimating the partial correlation coefficient on Classic Statistics (Inverse Method) and on Bayesian Statistics (Normal - Invese Wishart conjugate prior). In this current work, in order to solve the problem of having less observations than variables, we propose a new methodology called local partial correlation, which consists of selecting, for each pair of variables, the other variables most correlated to the pair. We applied these methods on simulated data and compared them through ROC curves. The most atractive result is that, even though it has high computational costs, to use Bayesian inference is better when we have less observations than variables. In other cases, both approaches present satisfactory results.

Nesta pesquisa, estudamos e comparamos duas maneiras de se construir redes. O principal objetivo do nosso estudo é encontrar uma forma efetiva de se construir redes, especialmente quando temos menos observações do que variáveis. A construção das redes é realizada através da estimação do coeficiente de correlação parcial com base na estatística clássica (inverse method) e na Bayesiana (priori conjugada Normal - Wishart invertida). No presente trabalho, para resolver o problema de se ter menos observações do que variáveis, propomos uma nova metodologia, a qual chamamos correlação parcial local, que consiste em selecionar, para cada par de variáveis, as demais variáveis que apresentam maior coeficiente de correlação com o par. Aplicamos essas metodologias em dados simulados e as comparamos traçando curvas ROC. O resultado mais atrativo foi que, mesmo com custo computacional alto, usar inferência Bayesiana é melhor quando temos menos observações do que variáveis. Em outros casos, ambas abordagens apresentam resultados satisfatórios. / This research is about studying and comparing two different ways of building complex networks. The main goal of our study is to find an effective way to build networks, particularly when we have fewer observations than variables. We construct networks estimating the partial correlation coefficient on Classic Statistics (Inverse Method) and on Bayesian Statistics (Normal - Invese Wishart conjugate prior). In this current work, in order to solve the problem of having less observations than variables, we propose a new methodology called local partial correlation, which consists of selecting, for each pair of variables, the other variables most correlated to the pair. We applied these methods on simulated data and compared them through ROC curves. The most atractive result is that, even though it has high computational costs, to use Bayesian inference is better when we have less observations than variables. In other cases, both approaches present satisfactory results.

<p>The number of MPC installations in industry is growing as a reaction to demands of increased efficiency. An MPC controller uses an internal plant model to run real-time predictive optimization of future inputs. If a discrepancy between the internal plant model and the plant exists, control performance will be affected. As time from commissioning increases the model accuracy tends to deteriorate. This is natural as the plant changes over time. It is important to detect these changes and re-identify the plant model to maintain control performance over time. A method for identifying Model Plant Mismatch for MPC applications is developed. Focus has been on developing a method that is simple to implement but still robust. The method is able to run in parallel with the process in real time. The efficiency of the method is demonstrated via representative simulation examples.An extension to detection of nonlinear mismatch is also considered, which is important since linear plant models often are used within a small operating range. Since most processes are nonlinear this discrepancy is inevitable and should be detected.</p> / <p>Ökade krav på effektivitet gör att industrin söker efter mer avancerad processtyrning. MPC har växt fram som en kandidat. En MPC regulator änvänder en modell av systemet för att samtidigt som systemet körs utföra en optimering av framtida styrsignaler. Om modellen innehåller felaktigheter kan reglerprestandan påverkas. En modell försämras normalt då tiden från idrifttagning växer eftersom systemet förändras med tiden. Det är av största vikt att upptäcka dessa förändringar och sedan uppdatera modellen för att reglerprestandan inte ska påverkas. Avsikten är att utveckla en metod för att upptäcka modellfel med fokus på att den ska vara enkel att implementera. Det ska även vara möjligt att använda metoden parallellt med en process. För att utvärdera metoden så körs den på ett antal representativa simuleringsexempel. Det har även varit en avsikt att utveckla en metod för detektion av ickelinjära modellfel. Motivet till det är att linjära modeller används för att beskriva ickelinjära processer och då är modellfel naturliga.</p>

This study had three purposes: (1) to identify differential item functioning (DIF) on the PPVT-III (Forms A & B) using a partial correlation method, (2) to find a consistent pattern in items identified as underestimating ability in each ethnic minority group, and (3) to compare findings from an expert judgment method and a partial correlation method. Hispanic, African American, and white subjects for the study were provided by American Guidance Service (AGS) from the standardization sample of the PPVT-III; English language learners (ELL) of Mexican descent were recruited from school districts in Central and South Texas. Content raters were all self-selected volunteers, each had advanced degrees, a career in education, and no special expertise of ELL or ethnic minorities. Two groups of teachers participated as judges for this study. The "expert" group was selected because of their special knowledge of ELL students of Mexican descent. The control group was all regular education teachers with limited exposure to ELL. Using the partial correlation method, DIF was detected within each group comparison. In all cases except with the ELL on form A of the PPVT-III, there were no significant differences in numbers of items found to have significant positive correlations versus significant negative correlations. On form A, the ELL group comparison indicated more items with negative correlation than positive correlation [χ2 (1) = 5.538; p=.019]. Among the items flagged as underestimating ability of the ELL group, no consistent trend could be detected. Also, it was found that none of the expert judges could adequately predict those items that would underestimate ability for the ELL group, despite expertise. Discussion includes possible consequences of item placement and recommendations regarding further research and use of the PPVT-III.

The number of MPC installations in industry is growing as a reaction to demands of increased efficiency. An MPC controller uses an internal plant model to run real-time predictive optimization of future inputs. If a discrepancy between the internal plant model and the plant exists, control performance will be affected. As time from commissioning increases the model accuracy tends to deteriorate. This is natural as the plant changes over time. It is important to detect these changes and re-identify the plant model to maintain control performance over time. A method for identifying Model Plant Mismatch for MPC applications is developed. Focus has been on developing a method that is simple to implement but still robust. The method is able to run in parallel with the process in real time. The efficiency of the method is demonstrated via representative simulation examples.An extension to detection of nonlinear mismatch is also considered, which is important since linear plant models often are used within a small operating range. Since most processes are nonlinear this discrepancy is inevitable and should be detected. / Ökade krav på effektivitet gör att industrin söker efter mer avancerad processtyrning. MPC har växt fram som en kandidat. En MPC regulator änvänder en modell av systemet för att samtidigt som systemet körs utföra en optimering av framtida styrsignaler. Om modellen innehåller felaktigheter kan reglerprestandan påverkas. En modell försämras normalt då tiden från idrifttagning växer eftersom systemet förändras med tiden. Det är av största vikt att upptäcka dessa förändringar och sedan uppdatera modellen för att reglerprestandan inte ska påverkas. Avsikten är att utveckla en metod för att upptäcka modellfel med fokus på att den ska vara enkel att implementera. Det ska även vara möjligt att använda metoden parallellt med en process. För att utvärdera metoden så körs den på ett antal representativa simuleringsexempel. Det har även varit en avsikt att utveckla en metod för detektion av ickelinjära modellfel. Motivet till det är att linjära modeller används för att beskriva ickelinjära processer och då är modellfel naturliga.

This study had three purposes: (1) to identify differential item functioning (DIF) on the PPVT-III (Forms A & B) using a partial correlation method, (2) to find a consistent pattern in items identified as underestimating ability in each ethnic minority group, and (3) to compare findings from an expert judgment method and a partial correlation method. Hispanic, African American, and white subjects for the study were provided by American Guidance Service (AGS) from the standardization sample of the PPVT-III; English language learners (ELL) of Mexican descent were recruited from school districts in Central and South Texas. Content raters were all self-selected volunteers, each had advanced degrees, a career in education, and no special expertise of ELL or ethnic minorities. Two groups of teachers participated as judges for this study. The "expert" group was selected because of their special knowledge of ELL students of Mexican descent. The control group was all regular education teachers with limited exposure to ELL. Using the partial correlation method, DIF was detected within each group comparison. In all cases except with the ELL on form A of the PPVT-III, there were no significant differences in numbers of items found to have significant positive correlations versus significant negative correlations. On form A, the ELL group comparison indicated more items with negative correlation than positive correlation [χ2 (1) = 5.538; p=.019]. Among the items flagged as underestimating ability of the ELL group, no consistent trend could be detected. Also, it was found that none of the expert judges could adequately predict those items that would underestimate ability for the ELL group, despite expertise. Discussion includes possible consequences of item placement and recommendations regarding further research and use of the PPVT-III.

No description available.

Graphical models are powerful tools when estimating complex dependence structures among large sets of data. This thesis restricts the scope to undirected Gaussian graphical models. An initial predefined sparse precision matrix was specified to generate multivariate normally distributed data. Utilizing the generated data, a simulation study was conducted reviewing accuracy, sensitivity and specificity of the estimated precision matrix. The graphical LASSO was applied using four different packages available in R with seven selection criteria's for estimating the tuning parameter. The findings are mostly in line with previous research. The graphical LASSO is generally faster and feasible in high dimensions, in contrast to stepwise model selection. A portion of the selection methods for estimating the optimal tuning parameter obtained the true network structure. The results provide an estimate of how well each model obtains the true, predefined dependence structure as featured in our simulation. As the simulated data used in this thesis is merely an approximation of real-world data, one should not take the results as the only aspect of consideration when choosing a model.

In the past years, several network reconstruction methods modeled as Gaussian Graphical Model in high dimensional settings where proposed. In this work we will analyze three different methods, the Graphical Lasso (GLasso), Graphical Ridge (GGMridge) and a novel method called LPC, or Local Partial Correlation. The evaluation will be performed in high dimensional data generated from different simulated random graph structures (Erdos-Renyi, Barabasi-Albert, Watts-Strogatz ), using Receiver Operating Characteristic or ROC curve. We will also apply the methods in the reconstruction of genetic co-expression network for the differentially expressed genes in cervical cancer tumors. / Vários métodos tem sido propostos para a reconstrução de redes em alta dimensão, que e tratada como um Modelo Gráfico Gaussiano. Neste trabalho vamos analisar três métodos diferentes, o método Graphical Lasso (GLasso), Graphical Ridge (GGMridge) e um novo método chamado LPC, ou Correlação Parcial Local. A avaliação será realizada em dados de alta dimensão, gerados a partir de grafos aleatórios (Erdos-Renyi, Barabasi-Albert, Watts-Strogatz ), usando Receptor de Operação Característica, ou curva ROC. Aplicaremos também os metidos apresentados, na reconstrução da rede de co-expressão gênica para tumores de câncer cervical.