published_or_final_version / Chemistry / Master / Master of Philosophy

Ontario’s Chronic Disease and Prevention Framework (CDPM) is a framework aimed at improving health outcomes and reducing costs. Currently, there is a paucity of data examining diabetes management (DM) in peritoneal dialysis (PD) programs. This study, carried out in 2010-11, describes dietitians’ perspectives regarding DM in PD programs in Ontario. Purposeful sampling of dietitians employed in PD programs (n=18) resulted in a response rate of 86.6%. A web-based survey collected data on demographic characteristics of PD clients, program models, and program-specific data regarding facilitators and barriers to provision of dialysis-specific diabetes education. Statistical analysis was completed and responses to open-ended questions examined using thematic open-coding. Findings suggest three major themes: “walking the CDPM talk”, dietitians as “unrecognized CDPM champions” and “the missing pieces to the CDPM puzzle”. Results suggest that while many dietitians have embraced CDPM, their capacity to fully integrate it into their practices is limited by organizational- and system-level barriers. / UOIT

Despite the decreasing incidence of peritoneal dialysis (PD) peritonitis over time, its occurrence is still associated with adverse outcomes. This thesis focuses on determining factors associated with PD peritonitis in order to facilitate identification of patients at risk. Using data collected in a multicentre Canadian database between 1996 and 2005, the study population comprised 4,247 incident PD patients, of whom 1,605 had at least one peritonitis episode. Variables independently associated with peritonitis included age [rate ratio (RR) 1.04 per decade increase, 95% CI 1.01-1.08], Black race (RR 1.37, 95% CI 1.00-1.88) and having transferred from hemodialysis (RR 1.24, 95% CI 1.11-1.38). There was an interaction between gender and diabetes (p=0.011), with an increased peritonitis risk only among female diabetics (RR 1.27, 95% CI 1.10-1.47). Choice of continuous ambulatory PD vs. automated PD did not influence peritonitis risk. These results contribute to our understanding of peritonitis risk among PD patients.

Despite the decreasing incidence of peritoneal dialysis (PD) peritonitis over time, its occurrence is still associated with adverse outcomes. This thesis focuses on determining factors associated with PD peritonitis in order to facilitate identification of patients at risk. Using data collected in a multicentre Canadian database between 1996 and 2005, the study population comprised 4,247 incident PD patients, of whom 1,605 had at least one peritonitis episode. Variables independently associated with peritonitis included age [rate ratio (RR) 1.04 per decade increase, 95% CI 1.01-1.08], Black race (RR 1.37, 95% CI 1.00-1.88) and having transferred from hemodialysis (RR 1.24, 95% CI 1.11-1.38). There was an interaction between gender and diabetes (p=0.011), with an increased peritonitis risk only among female diabetics (RR 1.27, 95% CI 1.10-1.47). Choice of continuous ambulatory PD vs. automated PD did not influence peritonitis risk. These results contribute to our understanding of peritonitis risk among PD patients.

Thesis (Ph. D.)--University of Hong Kong, 2002. / Includes bibliographical references (leaves 199-235).

Thesis (M.Sc. (Clinical Pharmacy))--Mahidol University, 1982.

Thesis (M.S.)--University of Wisconsin--Madison, 1984. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 99-101).

Thesis (doctoral)--University of Uppsala, 1983. / Includes bibliographical references (p. 38-46).

published_or_final_version / Medicine / Doctoral / Doctor of Philosophy

Thesis (M. Soc. Sc.)--University of Hong Kong, 2003.