Exercise training has consistently been shown to increase fat utilization during exercise, while conflicting results have been reported on the effects of sex and age on fuel metabolism during exercise. PURPOSE: The primary objective of this investigation was to compare fat and carbohydrate utilization during exercise among males and females varying in age and training status. METHODS: 8 groups of 10 subjects each were formed based upon trained (T)/untrained (U), male (M)/female (F), and young (Y)/older (O): TYM, TYF, UYM, UYF, TOM, TOF, UOM, UOF. All female subjects were experiencing regular menstrual cycles, not using oral contraceptives, and were tested in the mid-follicular phase of their menstrual cycle. The young subjects averaged 21.3 ��1.7 yr and older subjects 40.1 ��1.9 yr. All subjects exercised for 35 minutes on a treadmill at an intensity just below their ventilatory threshold. Substrate utilization was indicated by the respiratory exchange ratio (RER), and a 2x2x2 factorial ANOVA was used to determine whether age, sex, and training status have independent or interacting effects on substrate-utilization variables, and t-tests were used for post-hoc comparisons. RESULTS: The average RER during exercise was lower in trained subjects (0.841��.023) compared to untrained subjects (0.884��.021) (P < .05). There was no difference in the average RER during exercise between the young (0.860��.026) and older (0.865��.034) groups of subjects. The average RER during exercise was lower for untrained females (0.860��.027) than untrained males (0.870��.032) (P < .05), but there was no difference in fat and carbohydrate utilization between trained males (0.843��.023) and trained females (0.838��.022). CONCLUSION: The major finding of this study was that untrained females utilized proportionately more fat during exercise compared to untrained males, but there was no difference in fat and carbohydrate utilization between trained females and trained males. Another finding was that a 20-year difference in age was not sufficient for an age effect to be evident in fat utilization during moderate exercise. / Graduation date: 2013

<p>The study aims to understand the challenges facing the Itinerant Learning Support Educators in an Inclusive Education framework. At the onset of the study there were very limited research studies and literature available on the challenges facing Itinerant Learning Support Educators hence literature in the study drew on the development and history of Special Education towards a global shift with regard to Inclusive Education policy development. As such the literature was utilized to understand how global phenomena and policies in developed countries impact on local policy transformation and contexts. The study followed a qualitative research approach to explore the challenges facing Itinerant Learning Support Educators in performing their functions. To gain an in depth understanding of their perceptions a case study method was followed and data collection techniques included focus group interviews. The sample in this study comprised of 14 Itinerant Learning Support Educators. The data was analyzed using a thematic approach. The findings of this study highlighted that despite a shift towards Inclusive Education in South Africa, Itinerant Learning Support Educators found themselves challenged by a range of contextual issues that impacted on the effective delivery of inclusive principles and practices. The study recommends that the Department of Education should take cognisance of these challenges, review the job description of Itinerant Learning Support Educators and put clear guidelines and support structures in place to support them in functioning optimally within an Inclusive Education paradigm.</p>

Access to abstract permanently restricted to Ball State community only / Access to thesis permanently restricted to Ball State community only / School of Physical Education, Sport, and Exercise Science

Access to abstract permanently restricted to Ball State community only / Access to thesis permanently restricted to Ball State community only / School of Physical Education, Sport, and Exercise Science

Access to abstract is permanently restricted to Ball State community only / Access to dissertation permanently restricted to Ball State community only / School of Physical Education, Sport, and Exercise Science

The molecular form distribution of adenosine deaminase has been characterized in nine rat tissues. This study has also investigated the effects of 70% partial hepatectomy in liver, spleen, and intestinal tissues. In all tissues studied, the molecular weight of the enzyme was found to be 35,000 daltons, as determined by gel filtration chromatography. Two prominent isozymes of this molecular weight were identified by means of thin-layer isoelectric focusing. Isozymes with pI's of 4.95 and 4.80 were present in tissues of liver, spleen, and intestine of normal and hepatectomised rats. Throughout the liver regeneration period, activity levels of adenosine deaminase were elevated in all tissues examined.Ball State UniversityMuncie, IN 47306

Eight men were studied before and after an endurance training program to assess changes in the lipid metabolism of skeletal muscle. Training consisted of eight weeks of outdoor running with daily mileage increasing from one-half mile at the onset to four miles at the eighth veekof training. In vitro analyses of palmityl-CoA oxidation and the activities of carnitine palmityltransferase (CPT) and succinate dehydrogenase (SDH) were observed in muscle samples obtained by needle biopsy from the gastrocnemius before and after training.The subjects' maximal oxygen uptake increased from 3.47 1/min (± 0.26) to 3.82 1/min (± 0.21) as a result of the training. At the same time, muscle CPT and SDH increased (P <.01) 23% and 36%, respectively. The muscle's capacity to oxidize palmityl-CoA increased from 6.36 nmoles/min/g to 13.32 nmoles/min/g, a significant increase of 116% (P <.01).This investigation supports earlier findings with rats and emphasizes the influence of chronic endurance exercise on lipid metabolism in the skeletal muscle of man.Ball State UniversityMuncie, IN 47306

This study examined the effects of maintaining exercise training throughout pregnancy upon metabolic and physical properties of parametrial fat cells and fetal growth in Wistar rats. Eight weeks prior to mating the animals (n=10) were trained to run for 2 hrs/day, 5 days/wk at 31 m/min up an 8 0 incline. Control animals (n=6) remained sedentary. All animals were mated and trained animals resumed running on the second day of gestation. There was no variation in body weight (p > 0.05) between the trained (T) and sedentary control (S) rats at mating but S weight was significantly greater (p < 0.05) at Day 19. The T mothers had significantly smaller fat cells (p < 0.05) than S but cell number did not differ (p > 0.05). The rate of glucose oxidation (1C-1) by cells from T animals was significantly higher (p < 0.05) than the S in the presence of insulin, but much lower than oxidation rates of non-pregnant trained animals. In terms of the fetus, training reduced litter size (p < 0.05) and increased the incidence of fetal resorption. The results of this study indicate that the training adaptation of the adipocytes is largely lost during pregnancy but insulin responsiveness is maintained at a higher level than sedentary controls. This coupled with the apparent adverse effects of the training on the fetus suggests that exercise during pregnancy should be more closely investigated.Ball State UniversityMuncie, IN 47306

The effects of an 8-week swim training program and a 3-week detraining period on the size and protein composition of the heart of female Wistar rats were examined. The animals were separated into three groups: trained, detrained, and sedentary control. The training program, 6 hours/day, 5 days/week, resulted in a significantly larger dry heart weight, a normal collagen concentration, and a nonsignificantly greater total protein content. The greatest changes occurred between 4 and 6 weeks of training. The mild physiologic hypertrophy was assumed to be typical, and therefore simply an enlargement of a normal heart with proportional increases in myocyte size, and connective and vascular tissue hyperplasia. The detraining period produced a return of the heart mass to normal by the end of 2 weeks of detraining. The total protein content and collagen concentration remained elevated, though nonsignificant. The results indicate the detrained heart is composed of more connective, vascular, and metabolically active tissue, all of which may be important in the detrained heart’s response to increased work.Ball State UniversityMuncie, IN 47306

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