Thesis (Ph. D.)--University of Hong Kong, 2009. / Includes bibliographical references (leaves 242-260). Also available in print.

Thesis (M.H.S.A.)--University of Michigan, 1976.

Thesis (M.S.)--University of Michigan, 19977. / Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 19977 / Includes bibliographical references.

Thesis (M.S.)--University of Wisconsin-Madison, 1989. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 52-54).

Thesis (Ph. D.)--University of Washington, 2006. / Includes bibliographical references (leaves 131-148).

<b>Background</b> Cardiovascular risk scores are used to estimate absolute risk of disease and identify patients who will benefit most from treatments to lower risk. As a key risk factor for cardiovascular disease, blood pressure is accounted for in many risk scores, but is inherently variable and may be influenced by both biological and measurement factors. This thesis aims to determine how routinely collected blood pressure measurements should best be used for accurate estimation of cardiovascular risk. <b>Methods</b> This thesis describes four main studies. A patient survey and prospective study establish the current practice of blood pressure measurement. Secondary analyses of data from blood pressure monitoring trials determine how risk estimates may be affected by the use of different summary measures of blood pressure. A systematic review evaluates the evidence of an association between blood pressure variability and cardiovascular risk. Finally, a cohort study in the Clinical Practice Research Datalink determines if inclusion of blood pressure variability in cardiovascular risk scores may improve risk estimation. <b>Results</b> Current practice of blood pressure measurement may differ from that in risk score derivation studies. However, these differences have limited effects on cardiovascular risk estimates with few patients reclassified across risk thresholds. Increased long-term variability in blood pressure is in itself a risk factor for cardiovascular disease over and above mean blood pressure but its inclusion in a cardiovascular risk score does not materially improve the accuracy of risk estimates. <b>Conclusions</b> Healthcare professionals should continue to estimate risk for primary prevention of cardiovascular disease using the blood pressure measurements available to them, whether measured at home or in the clinic. There is also no additional benefit of considering measures of long-term blood pressure variability in risk estimation.

>Magister Scientiae - MSc / BACKGROUND: Following the historical suppression of traditional medicines in South Africa, the government published their National Health Plan in 1994 which made provision for traditional healing as an integral and recognised part of the health care system, inter alia, to establish a regulatory body for traditional medicines. Traditional medicines were included in the National Drug Policy for South Africa in 1996. A policy on traditional medicine was only drawn up in 2008 and is currently still in draft form. Some progress was made towards regulating traditional health practitioners; but very little towards regulating traditional medicines after its adoption into the National Health Plan over a decade ago. The aim of the study was to investigate how traditional medicines in South Africa can be effectively regulated with specific focus on the current status of traditional medicine regulation in South Africa; to highlight the challenges which have impeded progress towards regulating traditional medicines; and a review of regulatory strategies for traditional medicines in Ghana, India and the People’s Republic of China in an attempt to identify viable solutions to pave an effective way for regulating traditional medicines in South Africa.METHODS: The research design was exploratory and qualitative in nature following a deductive thematic analysis of data collected using a traditional literature review process. RESULTS: The delay in regulating traditional medicines in South Africa is due to a number of challenges where the most prominent is due to a lack in national priority to categorise African traditional medicine and to include it into the country’s national health system. Traditional medicines according to the World Health Organisation can be classified for inclusion into national health systems either as integrative or inclusive. Each of these inclusion strategies were presented by the chosen jurisdictions studied. An integrative health care system such as that used by China was found to be resource intensive in nature. An inclusive health care system as used in Ghana and India did not require traditional medicines as an integral part of the health care system and there were no expectations for the same requirements for regulating traditional medicines and allopathic medicines. What became apparent from the study was that irrespective of the inclusion strategy followed, there are still a number of challenges that obstruct the existence of an effective regulatory framework for traditional medicines with an overwhelming common factor of the instrumental role government play.

Made available in DSpace on 2014-06-11T19:35:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-02-26Bitstream added on 2014-06-13T18:46:02Z : No. of bitstreams: 1 garcia_as_dr_assis.pdf: 564858 bytes, checksum: 935036e4cf3add8f7461b01e407bf83e (MD5) / A Saúde é um campo de produção de conhecimento reconhecido como espaço de desenvolvimento de novos saberes a partir da práxis. Desenvolvemos a intercessão-pesquisa na Atenção Primária, tendo por objetivo compreender e analisar os processos de produção de conhecimento presentes na produção da Atenção à Saúde Mental, na ética da Atenção Psicossocial. Operamos com o Dispositivo Intercessor para integrar a produção de conhecimento em duas dimensões essenciais: a primeira consiste no Dispositivo Intercessor que opera na produção de conhecimento na práxis e a segunda dimensão é o Dispositivo Intercessor como Modo de Produção de Conhecimento que opera sobre os processos de produção do conhecimento na práxis, onde realizamos o mapeamento do campo de intercessão e trabalhamos os aspectos epistemológicos correspondentes a essa dimensão do conhecimento. Ocorreu neste processo a apropriação pela equipe participante, do conhecimento sobre os modos de fazer propostos para a Atenção Primária à Saúde e a importância de espaços de construção coletiva que precisam ser priorizados no cotidiano das equipes no Campo da Saúde como forma de mudança do modelo de Atenção à Saúde. Identificamos que a utilização do Dispositivo Intercessor se deu como um importante dispositivo de reorganização dos processos de trabalho das equipes e de sua apropriação sobre o processo de construção e reorganização do modelo de Atenção à Saúde Mental / Health is a field of knowledge production recognized as an area of development of new knowledge from practice. We develop a search-intercession in Primary Care, aiming to understand and analyze the processes of knowledge production present in the production of Care for Mental Health, Psychosocial Care of ethics. We operate with the Device Intercessor to integrate the production of knowledge in two key dimensions: the first is the Intercessor device that operates in the production of knowledge in practice and second dimension is the Device Mode as Intercessor Production of Knowledge that operates on production processes knowledge in practice, where we perform the mapping of the field work of intercession and epistemological aspects related to this dimension of knowledge. Occurred in this case ownership team participant knowledge about modes of making proposed for Primary Health Care and the importance of collective construction of spaces that need to be prioritized in the daily lives of the teams in the field of Health as a way to change the model of care Health. We identified that the use of the device Intercessor occurred as an important device for reorganizing work processes of teams and their ownership of the process of construction and reorganization of Mental Health Care

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