Made available in DSpace on 2016-08-29T15:32:26Z (GMT). No. of bitstreams: 1 tese_2364_Dissertacao Mestrado Rodrigo Rosenfeld Rosas.pdf: 653410 bytes, checksum: 63cb1400a0f68e88babaec03219cfc5a (MD5) Previous issue date: 2006-09-29 / Apesar de existirem vários robôs móveis, as soluções adotadas para sua programação são, normalmente, do tipo ad hoc. Alguns projetos foram criados com o objetivo de prover uma interface comum aos vários tipos de robôs móveis, mas nenhum parece ter alcançado os requerimentos de sistemas robóticos reais. A maioria não se importa com restrições de tempo, as quais são intrínsecas às aplicações robóticas. Suporte de tempo-real é um requisito muito importante para comportamento determinístico. Este trabalho compara as estruturas para programação de robôs móveis existentes e propõe uma nova estrutura (framework), através de critérios claros e objetivos. Esta estrutura é desenvolvida com base no sistema operacional Linux, utilizando uma extensão de tempo-real, para prover uma interface simples e flexível, adequada à programação de aplicações de robótica móvel, que possuem restrições de tempo severas. A extensão escolhida neste trabalho foi o projeto Xenomai, embora seja possível adaptar a solução para outras extensões como RTAI ou RTLinux. A estrutura proposta permite obter latências da ordem de micro-segundos, além de facilitar bastante o processo de desenvolvimento de aplicações com robôs móveis

Les jeux vidéo font aujourd'hui partie de la culture de nombreux étudiants au même titre que la télévision, les films ou les livres. Or depuis quelques années, les étudiants se détournent des sciences. La recherche dans le domaine de l'enseignement de l'informatique aborde les problèmes du recrutement et du maintien des étudiants dans les formations informatiques. Une approche prometteuse consiste à utiliser la culture vidéoludique des étudiants pour les motiver à investir du temps dans la pratique de la programmation. Dans ce cadre, les travaux présentés portent sur la conception, la réalisation et l'évaluation d'un jeu sérieux pour l'apprentissage des fondamentaux de la programmation. Ce jeu est basé sur un jeu de stratégie temps réel où la programmation est un moyen d'interaction. Grâce au système Prog&Play, le jeu sérieux a pu être déployé et évalué dans différents contextes d'enseignements.

Das Nebennierenrindenkarzinom ist ein seltener maligner, epithelialer Tumor mit einer jährlichen Inzidenz in Deutschland von 2 pro 1 Million Einwohnern. Es ist für etwa 0,2% aller Krebstodesfälle verantwortlich. Die Seltenheit der Erkrankung erschwert die Entwicklung wirksamer Therapieansätze erheblich. Erst in letzter Zeit gelang es, größere Patientenkohorten in kontrollierten Studien zu behandeln (Allolio et al. 2006) und größere Fallzahlen an Tumorgewebe wissenschaftlichen Untersuchungen zuzuführen. Erstmalig besteht damit auch die Möglichkeit, die Expression eventuell relevanter Proteine für moderne Therapiekonzepte auch an großen Fallzahlen zu untersuchen. Bislang liegen nur sehr lückenhafte diesbezügliche Studien vor. In der vorliegenden Arbeit wurde die Expression einiger möglicherweise therapeutisch relevanter Proteine mittels immunhistochemischer Analyse unter Zuhilfenahme der Tissue Microarray-(TMA)-Technik in einer großen Serie von 104 NNR-Ca untersucht und mit der von Nebennierenadenomen und normalem Nebennierengewebe verglichen. Insgesamt 9 verschiedene Proteine wurden immunhistochemisch dargestellt: Als wichtigster Befund wurde eine Überexpression der Alpha-methylacyl-CoA Racemase (AMACR) in 89% der untersuchten NNR-Ca festgestellt. Interessanterweise zeigte auch die Mehrzahl der untersuchten Nebennierenadenome (80%) zumindest eine schwache AMACR-Reaktivität, während die mituntersuchten normalen Nebennieren negativ blieben. Diese bislang nicht beschriebene Beobachtung gleicht den bekannten Befunden z.B. in der Prostata, in der sowohl die dort entstehenden Adenokarzinome, als auch deren Vorläuferläsionen (PIN) eine AMACR-Expression zeigen. EGFR, ein Tyrosinkinaserezeptor, auf den der bereits etablierte therapeutische Antikörper Cetuximab (Erbitux®) zielt, wurde in 49% der untersuchten NNR-Ca verstärkt exprimiert, so dass eine gegen den EGFR gerichtete Therapie in ausgewählten Fällen eine Behandlungsoption zu eröffnen scheint. Die Suche nach Mutationen in diesem potentiellen Zielprotein könnte weitere Ansatzpunkte für Wirkstoffe aufzeigen, Studien gibt es dazu bislang keine. Ähnliche Ergebnisse fanden sich in dieser Studie für VEGF, das von 19% der untersuchten NNR-Ca mäßig oder stark exprimiert wurde. Auch hier könnte eine entsprechende Therapie mit einem bereits kommerziell erhältlichen spezifischen Antikörper (Bevacizumab/Avastin®) in einem Teil der Fälle eine Behandlungsoption, ggf. auch als supportive Maßnahme, eröffnen. Angesichts der Expression von VEGF in nur rund einem Drittel der Fälle, wäre hier aber eine vorangehende Bestimmung des Expressionsstatus am Tumorgewebe unerläßlich. Weitere Untersuchungen sollten auch den VEGF-Rezeptor als möglichen Ansatzpunkt neuer Wirkstoffe, wie z.B. der Multi-Tyrosinkinase-Inhibitor Sunitinib [SU11248; SUTENTTM] (Le Tourneau et al., 2007), erforschen. Im Gegensatz dazu wurde eine wesentliche Expression weiterer untersuchter Proteine (CD117/C-kit, Her-2/neu, Östrogen- und Progesteronrezeptor) in NNR-Ca in dieser Studie nicht in einem Maße gefunden, welches in einer signifikanten Zahl von Fällen eine Therapieoption eröffnen würde. Eine immunhistochemisch bestimmbare Expression von p53, als Surrogatmarker für ein mutiertes p53-Gen wurde in 85% der untersuchten NNR-Ca nachgewiesen. Dies weist auf eine zentrale Bedeutung von p53-Mutationen in der Genese von NNR-Ca hin. (Reincke et al., 1994; Gicquel et al., 2001; Barzon et al.I, 2001; Soon et al., 2008) Auch die Proliferationsfraktion, bestimmt als Ki67-Index, war in den untersuchten Karzinomen gegenüber den Adenomen und den mitgeführten normalen Nebennieren deutlich erhöht, was das aggressive Wachstumspotential der Mehrzahl der NNR-Ca wiederspiegelt. / Adrenocortical carcinoma (ACC) is a rare malignant epithelial neoplasm. It’s annual incidence is 2 out of 1000000 residents. Being a rare disease the developing of new treatments and the research about this neoplasm is rather difficult. In our immunohistological study we examined 104 cases of ACC with the tissue microarray-(TMA) technique and compared it with samples of normal adrenocortical tissue. Furthermore we analysed different adrenocortical adenomas. The proteins in our interest were: Alpha-methylacyl-CoA Racemase (AMACR), estrogen, progesteron, Ki67, p53, CD117 (c-kit), HER-2/neu, EGFR and VEGF. The most important finding was the overexpression of AMACR in 89% of ACC. EGFR, which already has an therapeutic agent named Cetuximab, is overexpressed in 49% of the ACC-samples . Bevacizumab is a therapeutic antibody against VEGF. It could be useful in some patient or at least as a supportive measure in therapy, because it’s expression was modest or intense in 19% of ACC.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-27T13:30:32Z No. of bitstreams: 5 2.pdf: 984350 bytes, checksum: 04e03f5d860785728cd837db9f0819af (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20626 bytes, checksum: 7851d446050a985bd0603b7c4cee472d (MD5) license_rdf: 19710 bytes, checksum: aa65da15f424ff71c620a992a187295c (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-27T16:32:20Z (GMT) No. of bitstreams: 5 2.pdf: 984350 bytes, checksum: 04e03f5d860785728cd837db9f0819af (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20626 bytes, checksum: 7851d446050a985bd0603b7c4cee472d (MD5) license_rdf: 19710 bytes, checksum: aa65da15f424ff71c620a992a187295c (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Made available in DSpace on 2015-02-27T16:32:20Z (GMT). No. of bitstreams: 5 2.pdf: 984350 bytes, checksum: 04e03f5d860785728cd837db9f0819af (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20626 bytes, checksum: 7851d446050a985bd0603b7c4cee472d (MD5) license_rdf: 19710 bytes, checksum: aa65da15f424ff71c620a992a187295c (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) Previous issue date: 2009 / A baixa taxa de germina??o pode ser o principal fator respons?vel pelo desest?mulo ?s pr?ticas de plantios comerciais de pequizeiro (Caryocar brasiliense Camb.). O objetivo deste trabalho foi verificar os fatores ambientais (localiza??o geogr?fica), proced?ncia, prog?nie, ?cido giber?lico e tempo de armazenamento das sementes na emerg?ncia de pl?ntulas dessa esp?cie. Foram coletadas sementes de prog?nies (matrizes) oriundas dos munic?pios mineiros de S?o Gon?alo do Rio Preto, Curvelo e Serro ? distrito de S?o Gon?alo do Rio das Pedras. As sementes foram coletadas em janeiro de 2005 e 2007 para o experimento 1 e em janeiro de 2007 e 2008 para o experimento 2, sendo semeadas em dois munic?pios: Diamantina (ambiente de baixa temperatura) e Curvelo (ambiente de alta temperatura). Os dados foram analisados atrav?s de testes Qui-quadrado para independ?ncia. Para os experimentos 1 e 2, conduzidos em Curvelo, todos os fatores foram altamente significativos (P<0,1%), exceto o efeito de proced?ncia (P = 6,89%) e do ?cido giber?lico (P = 6,08%), ambos do experimento 1. No experimento 1, conduzido em Diamantina, nenhum fator foi significativo a 10%, exceto o tempo de armazenamento (P = 5,64%) e o efeito ambiental (P<0,01%). J? no experimento 2, conduzido em Diamantina, todos os fatores foram significativos a 5%. A n?o signific?ncia para a maioria dos fatores em Diamantina no experimento 1 foi em decorr?ncia da baix?ssima taxa de germina??o nesse ambiente (apenas 11 sementes germinaram, de um total de 2010). A diferen?a de germina??o foi tamb?m significativa entre os dois ambientes - Curvelo e Diamantina, para os dois experimentos. Entretanto, no experimento 2, a germina??o foi menor em Curvelo, contrariando as expectativas. Acredita-se que a ocorr?ncia desse fato seja porque no ano de 2008 a sementeira em Diamantina foi montada no ch?o e n?o suspensa, como em Curvelo. A varia??o t?rmica seria maior no leito de areia suspenso por estar com a parte inferior exposta ? temperatura ambiente. Conclui-se que: a) a emerg?ncia em pl?ntulas de pequizeiro ? influenciada tanto por fatores gen?ticos como ambientais; b) a frequ?ncia de emerg?ncia em pl?ntulas de pequizeiro ? altamente influenciada pela planta matriz da qual foram colhidas; c) O efeito de popula??es (proced?ncias) na emerg?ncia em pl?ntulas de pequizeiro pode ser decorrente do pequeno tamanho dessas popula??es, confundindo-se com o efeito de matrizes; d) O tratamento de sementes de pequizeiro com ?cido giber?lico pode n?o ser garantia de maior emerg?ncia; e) O tempo de armazenamento de sementes de pequizeiro influencia consideravelmente a taxa de emerg?ncia. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Produ??o Vegetal, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2009. / ABSTRACT Pequi (Caryocar brasiliense Camb., caryocaraceae) is a widely distributed but endangered Brazilian Cerrado tree specie and its fruits are very appreciated by populations living in this biome. Observations show that temperature fluctuations, a common phenomenon observed among different altitudes, seems to have a strong influence on pequi seeds emergency. Genetic factors appears also to play an important role on this issue. These were the main focus on this work. Seeds from many progenies from three pequi populations (S?o Gon?alo do Rio Preto; Curvelo; and Serro, all of them in Minas Gerais State), strongly distanced from each other, were collected. The 3997 seeds collected in January of 2005 and 2007 years (Trial 1) and the 7035 ones collected in January of 2007 and 2008 years were sown proportionally in Diamantina, MG (a high altitude environment - roughly 1400m) and Curvelo, MG (a low altitude environment ? roughly 650m). The data were collected and organized in contingence tables. The hypothesis for population, progeny (tree), gibberellic acid (GA3), seed age (date of collection) and altitude (temperature) effects were tested by qui-square test for independence. For the trials carried out in Curvelo (high average temperature) in 2007 year, all tested effects were significant (P<0,1%), except populations (P=6,9%) and GA3 (P=6,1%), the last one reducing instead of, as expected, increasing the emergency rate. In the trials carried out in Diamantina (low average temperature) in 2007 year, the probabilities for qui-square tests were all over 10% except seed age (P=5,6%) and progenies (P=9,7%). In 2008 year all effects were significant (P<5%) for both locations. The temperature effects were also significant (P<5%) for the two years, however, against the expectations, in 2008 year, Curvelo (high average temperature) showed a lower emergency rate than Diamantina. The hypothesis to explain it was that the seed plot position was put directly on ground in Diamantina in this year, contrasting with the lifted ones in both locations in 2007 year and in Curvelo in 2008 year. This hypothesis was tested by comparing seed plots lifted with those sow directly on ground in both locations. The results showed that the emergency rate was significantly lower in the seed plots lifted in both Diamantina and Curvelo locations compared to those put directly on ground. May be the night and day temperature fluctuations affect more intensely the lifted seed plot. The main conclusions were: a) pequi seeds emergency are influenced by both genetic and environmental factors; b) it is highly influenced by their original progeny tree; c) progeny tree can also be the main factor responsible for population effects when the population sample is small; d) gibberellic acid is not a guarantee for better emergency in pequi seeds; e) the storage time has a considerable influence on their emergency rate; f) strong day and night temperature fluctuations can reduce the emergency rate in pequi seeds.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-27T13:30:31Z No. of bitstreams: 5 14.pdf: 606135 bytes, checksum: 9d0229829810f0c2806dc9a3cf114610 (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20904 bytes, checksum: e09bf99e64678e4285abf3ef3e05412d (MD5) license_rdf: 22564 bytes, checksum: ff373f1ad387898ef8ba4f8bc9e37073 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-27T14:49:46Z (GMT) No. of bitstreams: 5 14.pdf: 606135 bytes, checksum: 9d0229829810f0c2806dc9a3cf114610 (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20904 bytes, checksum: e09bf99e64678e4285abf3ef3e05412d (MD5) license_rdf: 22564 bytes, checksum: ff373f1ad387898ef8ba4f8bc9e37073 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Made available in DSpace on 2015-02-27T14:49:46Z (GMT). No. of bitstreams: 5 14.pdf: 606135 bytes, checksum: 9d0229829810f0c2806dc9a3cf114610 (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20904 bytes, checksum: e09bf99e64678e4285abf3ef3e05412d (MD5) license_rdf: 22564 bytes, checksum: ff373f1ad387898ef8ba4f8bc9e37073 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) Previous issue date: 2010 / A estima??o de par?metros gen?ticos em esp?cies vegetais perenes ? comumente feita por meio de delineamentos gen?tico-estat?sticos que levam em considera??o efeitos de prog?nies e popula??es. Dados de experimentos com essas bases n?o existem para o pequi. O presente trabalho teve por objetivo avaliar caracteres de crescimento e estimar par?metros gen?ticos em Pequi (Caryocar brasiliense Camb.) no est?gio precoce. O experimento foi instalado com mudas oriundas de 31 prog?nies (matrizes), de duas proced?ncias (Curvelo, MG e S?o Gon?alo do Rio Preto, MG) utilizando um Delineamento em Blocos Casualizados com seis repeti??es e cinco plantas por parcela, no munic?pio de Carbonita, MG. Foram avaliados os caracteres altura de planta (cm), em setembro de 2005; altura de planta e di?metro do caule ao n?vel do solo (mm), em fevereiro de 2006 e fevereiro de 2007; e altura de planta, di?metro do caule ao n?vel do solo e di?metro da copa (cm), em setembro de 2008. A estima??o dos par?metros gen?ticos foi feita utilizando-se o Software SELEGEM ? REML/BLUP e as estimavas dos coeficientes de correla??es fenot?picas e gen?ticas entre os caracteres e avalia??es foram obtidas a partir das estimativas dos valores fenot?picos e gen?ticos, respectivamente. As estimativas da herdabilidade no sentido restrito para todos os caracteres avaliados variaram de 0,15 a 0,50. Os coeficientes de varia??o gen?tica individual (CVgi%) de um modo geral foram moderadas. Os coeficientes de determina??o de efeitos de parcela (c2parc) foram de baixa magnitude para todos os caracteres, indicando pouca varia??o ambiental entre estas. As correla??es gen?ticas e fenot?picas foram todas positivas, de elevadas magnitudes e, em sua maioria, altamente significativas. As estimativas de efici?ncia de sele??o obtidas pela express?o de Hamblin & Zimmermann variaram de m?dias a altas para os tr?s caracteres considerados. Portanto, embora n?o sejam de import?ncia direta, os caracteres de crescimento podem ser ?teis na discrimina??o precoce de prog?nies com alta produ??o de frutos ou outras caracter?sticas desejadas, caso sejam geneticamente correlacionados a eles. A sele??o baseada em tais caracteres diminuiria custos e tempo para se completar um ciclo de sele??o, aspecto importante principalmente em esp?cies em que os caracteres de interesse levam anos para se expressarem, como ? o caso da produ??o de frutos em pequi. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Produ??o Vegetal, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2010. / ABSTRACT Genetic parameters for perennial crops are commonly estimated by genetic-statistical designs considering progenies and populations effects. In pequi, a Brazilian endangered and very important tree, there are no data come from these kind of experiments.?This work aimed to evaluate the growth and estimate genetic parameters in early stages for pequi. The trial was installed in Carbonita, MG, with seedlings of 31 trees (progenies) coming from two populations (Curvelo, MG and S?o Gon?alo do Rio Preto, MG) in a randomized block design with six replicates and five plants per plot.?The traits evaluated were: plant height (cm) in September, 2005; plant height and stem diameter at ground level (mm) in February, 2006 and February, 2007; and plant height, stem diameter at ground level and crown diameter (cm) in September, 2008.?Genetic parameters were estimated using the Software SELEGEN- REML/BLUP. Phenotypic and genetic correlation coefficients among traits and evaluations were estimated through phenotypic and genetic values, respectively.?The estimates of narrow sense heritability ranged from 0.15 to 0.50 for all traits. In general, the?coefficients of individual genetic variation (CVgi%) were moderate. The environmental effects among plots were small as showed by the determination coefficient of plots.?Genetic and phenotypic correlation estimates were all positive and, in general, highly significant.?The estimates of Hamblin & Zimmermann Selection Efficiency ranged from intermediate to high for all traits evaluated. Therefore, the growth traits may be useful in early discrimination of progenies with high fruit yield and other desired traits if they are genetically correlated to them.?Selection based on such traits would reduce costs and time to complete one cycle of selection, especially important in species which the traits of interest take years to express, as is the case of fruit yield in pequi.

Made available in DSpace on 2014-07-29T14:44:41Z (GMT). No. of bitstreams: 1 Dissertacao Luciano Rogerio do Espirito Santo Abrao.pdf: 3624894 bytes, checksum: f9587da07a9487394d1021de40ae359c (MD5) Previous issue date: 2011-08-17 / The occupation of Brazilian territory, since the portuguese invasion, has always been a state project built without taking into account the needs of the working classes, which participation was limited to pure physical effort. In Brazil social inequalities have historical roots. The process of appropriation of space, in all its stages, was directed toward such rooting, both in the colonial phase, as in the State phase (Empire and Republic). Such inequalities challenge the Social Sciences and Humanities to develop researches in order to understand them, and, even, in some cases, to present subsidies to its overcoming. During most of the political history of brazilian State people of social working classes were officially ignored, which resulted in the non-adoption of public policies of combat the inequalities. In fact, the republican Brazil comes to the present day with an immense social debt as a result of territorial rootedness of social inequalities. Debt that presents itself notorious when studied from the spatial area of the Brazilian municipalities. Instance of local Government, is in the City where people live, that the socio-spatial inequalities are identified in a more explicit way because of a greater proximity between the government and the citizen. It is also in the City that the weaknesses of political and administrative practices of combat the inequalities acquire greater visibility. In this research was proposed an exegesis of the historical-geographical process and legal of rooting of social inequalities in Brazil, of the spatialization and effectiveness of programs to combat them in the City of Catalão (GO), in order to understand the territorialization of social inequalities, the sócio-political fundamentals of its genealogy, the legitimating assumptions, as well as the policies of public assistance, identifying in the city of Catalão which are, where are and how live the beneficiaries of such policies. The research methodology included: a) theoretical research, in which was made the survey of the main references on the subject; b) documentary research, as well as the research in public agencies and database of public and private institutions; c) field research, made possible through interviews with public authorities of the administrative area related to the research and people linked to the civilian entities who are active in the social field, and, by sampling, with holders of benefits of Bolsa Família Program PBF, in a universe of 2,658 families assisted by the same in the City of Catalão GO. / A ocupação do território brasileiro, desde a invasão portuguesa, sempre foi um projeto de Estado construído sem levar em consideração as necessidades das classes trabalhadoras, cuja participação se limitou ao puro esforço físico. No Brasil as desigualdades sociais têm raízes históricas. O processo de apropriação espacial, em todas as suas etapas, foi direcionado no sentido de tal enraizamento, tanto na fase colonial, quanto na de Estado (Império e República). Tais desigualdades desafiam as Ciências Sociais e Humanas a desenvolverem pesquisas com o objetivo de compreendê-las, e, até, em alguns casos, apresentar subsídios para a sua superação. Durante a maior parte da história política do Estado brasileiro as pessoas das classes sociais trabalhadoras foram oficialmente desprezadas, o que redundou na não adoção de políticas públicas de combate às desigualdades. Na realidade, o Brasil republicano chega aos dias atuais com uma dívida social imensa face ao enraizamento territorial das desigualdades sociais. Dívida esta que se apresenta notória quando estudada a partir do recorte espacial dos Municípios brasileiros. Instância de Poder local, é no Município que as pessoas vivem, nele as desigualdades sócio-espaciais são identificadas de uma maneira mais explícita por causa de uma maior proximidade entre o poder e o cidadão. É também no Município que as fragilidades das práticas político-administrativas de combate as desigualdades adquirem uma visibilidade maior. Nesta pesquisa se propôs uma exegese do processo histórico-geográfico e jurídico de enraizamento das desigualdades sociais no Brasil, da espacialização e eficácia dos Programas de combate às mesmas no Município de Catalão (GO), com o objetivo de compreender a territorialização das desigualdades sociais, os fundamentos sociopolíticos de sua genealogia, os pressupostos legitimadores, bem como, as políticas públicas assistenciais, identificando no Município de Catalão quais são, onde estão e como vivem os beneficiários de tais políticas. A metodologia da pesquisa compreendeu: a) pesquisa teórica, na qual foi feito o levantamento das principais referências sobre o tema; b) pesquisa documental, bem como a pesquisa em órgãos públicos e banco de dados de instituições públicas e privadas; c) Pesquisa de campo, viabilizada por meio de entrevistas com autoridades públicas da área administrativa relacionada à pesquisa e pessoas ligadas às entidades civis que militam no campo social, e, por amostragem, com titulares de benefícios do Programa Bolsa Família PBF, em um universo de 2.658 famílias assistidas pelo mesmo no Município de Catalão GO.