Pulmonary diffusing capacity for nitric oxide (DLNO) is a relatively new pulmonary function test to assess gas transfer in the lung. To date, there are no prediction equations made for healthy adult African-American (black) subjects. Thus, the purpose of this study was to create prediction equations for DLNO in this ethnic/racial group. A total of 59 healthy subjects (27 males and 32 females) were recruited to perform pulmonary function testing at Georgia State University. They were diverse in age (18-67 yr), height (140-189 cm), and body mass index (17.2-32.3 kg/m2). All subjects completed single-breath maneuvers at rest inhaling 43 ± 4 ppm NO with a standard diffusion mixture. The breath-hold duration was 5.6 ± 0.6 s. Multiple linear regression predicted DLNO based on the subject’s age, height, and sex. The prediction equation for DLNO (mL/min/mmHg) = 0.92·(height in cm) +38.8·(sex) – 0.012·(age2) – 25, where 1 = male, 0 = female for sex. About 77% of the variance in DLNO was accounted for by sex (67%), age2 (7%), and height (4%). The standard error of the estimate in predicting DLNO was 16.3 mL/min/mmHg. Those with higher resting heart rates had a lower DLNO (r =-0.28, p = 0.03) but it was not included in the regression model as it did not enhance the fit. Black males had a 7-10% lower DLNO and black females had a 12-15% lower DLNO compared to matched white subjects. Black males of the same age and height had a 10% smaller alveolar volume, while black females had a 15% lower alveolar volume compared to matched white subjects. In conclusion, DLNO values and alveolar volumes are reduced in blacks compared to matched whites. The regression model presented best predicts DLNO in African-Americans below 40 years of age.

M.Phil. / The effects of an upper body resistance training (UBRT) programme on spirometry values are not well documented or researched. The sparse number of studies that have focussed on this topic have generated inconclusive data on the effects of UBRT on pulmonary function. The present investigation made use of an eight-week UBRT programme in order to evaluate whether this would yield significant changes with regards to the following spirometry values: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), 25% of forced expiratory flow (FEF-25), 50% of forced expiratory flow (FEF-50), 75% of forced expiratory flow (FEF-75), FEV1/FVC ratio, peak expiratory flow (PEF), peak inspiratory flow (PIF), vital capacity (VC), inspiratory vital capacity (IVC), FEV1/VC ratio, expiratory reserve volume (ERV) and minute ventilation (VE). The study made use of 36 sedentary but healthy male smokers (mean age: 33 years and 6 months), who were assigned into either a non-exercising control (CG) (n = 18) or exercising experimental (EG) (n = 18) group. A seven-day smoking analysis was recorded for both the EG and CG before and after the eight-week experimental period in order to control for any changes that might have occurred with regards to their smoking behaviour in an attempt to account for any changes in pulmonary function. The EG group were assigned to exercise for eight-weeks three times weekly on non-consecutive days using an UBRT programme. Their spirometry values were assessed at the commencement of and subsequent to the eight-week period. The EG¡¦s training programme consisted of latissimus-dorsi pulls, seated chest press, seated rows, seated shoulder press, shoulder shrugs, bent knee crunches and diagonal crunches. Each exercise was performed for three sets of 15 repetitions each. These exercises were performed at 50% 1-repetition maximum (1-RM) for the first week, at 60% 1-RM for the second and third week and at 70% 1-RM for the fourth week. Once each subject¡¦s 1-RM was reevaluated after four weeks, the same intensity progression was followed for the fifth (50% 1-RM), sixth (60% 1-RM), seventh (60% 1-RM) and eighth (70% 1-RM) weeks. The CG was instructed to not take part in any structured exercise throughout the eight-week period. The present investigation made use of the dependent and independent paired t-tests. The CG¡¦s FEV1/VC ratio increased significantly (p „T 0.05) by 2.97% and VC decreased significantly by 4.46%, while the EG¡¦s PEF and PIF increased significantly by 12.6% and 13.9%, respectively. No statistically significant changes were found in FVC, FEV1, FEV1/FVC ratio, FEF-25, FEF-50 and FEF-75, IVC, ERV and VE for both the EG and CG. Both groups indicated no statistically significant changes in daily cigarette consumption from the pre- to post-tests. The investigation concluded that eight weeks of UBRT was insufficient to result in significantly positive changes in the majority of pulmonary function variables, except for PIF, in sedentary male smokers. / Dr. L. Lategan

Introdução: Já se sabe que as alterações na atuação da força da gravidade promovidas pela mudança de postura, influenciam os volumes e capacidades pulmonares, mas o comportamento das propriedades elásticas e plásticas do pulmão ainda não está bem esclarecido na literatura. Objetivo: Avaliar a resistência do sistema respiratório em sujeitos eutróficos e obesos nos diferentes decúbitos. Métodos: Os participantes foram alocados nos diferentes grupos, de acordo com o índice de massa corpórea (IMC Kg/m2 ), sendo eles: 18-25, 25-29, 30-39, 40-49 e >50. As posições foram avaliadas pelo Sistema de Oscilometria de Impulso (IOS) em ordem aleatória: sentada (Se), supina (Su) e decúbitos laterais, esquerdo (DLE) e direito (DLD), sendo obtidos os seguintes parâmetros: resistências total, central e periférica, reatância e frequência de ressonância. A espirometria foi realizada em seguida para a análise das seguintes variáveis: capacidade vital forçada, volume expiratório forçado no primeiro segundo, a relação VEF1/CVF e fluxo expiratório forçado médio. Resultados: Foram recrutados 110 voluntários, 36 com IMC de 18 a 25 Kg/m2 (26,8 anos; 21,7 Kg/m2 ), 19 com IMC de 25 a 29 Kg/m2 (26,1 anos; 26,6 Kg/m2 ), 21 com IMC de 30 a 39 Kg/m2 (30 anos; 34,5 Kg/m2 ), 21 com IMC de 40 a 49 Kg/m2 (35,4anos; 45 Kg/m2 ) e 13 com IMC>50 Kg/m2 (35,5 anos; 54,2Kg/m2 ). Não foram detectados distúrbios ventilatórios pela espirometria (médias acima de 80% do previsto). Os grupos começaram a se diferenciar a partir da faixa de 30-39 Kg/m2 , houve diferenças importantes entre os indivíduos com IMC>50 e 40-49 com aqueles com IMC<25 e 25-29 principalmente em vias periféricas (p<0,0001). A posição supina apresentou maiores valores de resistência para todos os grupos. Essas diferenças frente às mudanças de decúbito são mais frequentes nas faixas de IMC menores (<25 a 29 Kg/m2 ). Conclusão: Há maior impedância do sistema respiratório em sujeitos obesos, com maior contribuição da resistência periférica, porém com menores variações relacionadas à mudança de posição em comparação aos sujeitos eutróficos. / Background: It is known that changes in gravity force action, promoted by change of posture, influence volumes and capacities lung, but the behavior of lung elastic and plastic properties, has not yet well clarified in literature. Aim: To evaluate the effect of different positions on respiratory system resistance. Methods: Participants were allocated to different groups, according to the body mass index (BMI Kg/m2 ). The positions were evaluated by Impulse Oscillometry System (IOS) in a random order: seated (Se), supine (Su), left lateral (LL) or right lateral decubitus (RL) and following parameters was obtained: total, central and peripheral resistance, reactance and resonant frequency. Spirometry was then performed to analyze the following variables: forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC and mean forced expiratory flow (FEF25-75%). Results: A total of 110 volunteers were recruited, 36 with BMI<25 kg/m2 (26.8 years, 21.7 kg/m2 ), 19 with BMI between 25-29kg/m2 (26.1 years, 26.6 kg/m2 ), 21 with BMI between 30-39 kg/m2 (30 years, 34.5 kg/m2 ), 21 with BMI between 40-49 kg/m2 (35.4 years, 45 kg/m2 ) and 13 with BMI> 50 kg/m2 (35.5 years, 54.2 kg/m2 ). No ventilatory disturbances were detected by spirometry, all higher than predicted (80%). The groups began to differentiate from the range of 30-39 kg/m 2 , there were important differences between individuals with BMI>50 and 40-49 with those with BMI <25 and 25-29, mainly in peripheral pathways (p<0.0001). The supine position presented higher resistance values for all groups. These differences compared to changes in decubitus are more frequent in the lower BMI ranges (<25 to 29 kg/m 2 ). It was also observed that overweight individuals tend to follow the same pattern as those with BMI within normal range. Conclusion: The respiratory impedance is higher in obese than eutrophic subjects, with more contribution of peripheral resistance, but with smaller variations related to position change when compared to eutrophic ones.

Liu, Tak Chi. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2011. / Includes bibliographical references (leaves 112-125). / Abstracts and appendixes in English and Chinese. / Abstract --- p.i / Acknowledgements --- p.viii / List of tables --- p.ix / List of figures --- p.xiii / List of Abbreviations --- p.xvi / List of Unit Abbreviations --- p.xvii / Table of Contents --- p.xviii / Chapter Chapter 1: --- Background and introduction --- p.P.1 / Chapter Chapter 2: --- Subjects and methods --- p.P.7 / Chapter 2.1 --- Study design and sampling frame --- p.P.7 / Chapter 2.2 --- Sample size calculation --- p.P.8 / Chapter 2.3 --- Study population --- p.P.11 / Chapter 2.4 --- Subject assessment in participating kindergartens --- p.P.13 / Chapter 2.5 --- Quality control for spirometric measurements --- p.P.18 / Chapter 2.6 --- Statistical analysis --- p.P.20 / Chapter 2.7 --- Outcome measures --- p.P.23 / Chapter 2.8 --- Participation and role in this study --- p.P.24 / Chapter Chapter 3: --- Results --- p.P.26 / Chapter 3.1 --- Comparison between the study populations in the training and research phases --- p.P.26 / Chapter 3.1.1 --- "Response rate, participation rate and success rate" --- p.P.27 / Chapter 3.1.2 --- Other factors --- p.P.31 / Chapter 3.2 --- Comparison between participants and non-participants in the research phase --- p.P.33 / Chapter 3.3 --- Comparison of factors between the subjects who succeed and failed to provide acceptable spirometric maneuvers which meet ATS/ERS standards in the research phase --- p.P.36 / Chapter 3.4 --- Comparison of lung function parameters between subjects who met and failed to meet the health criteria in the research phase --- p.P.39 / Chapter 3.4.1 --- Gestational birth age (< 37 weeks vs > 37 weeks) --- p.P.40 / Chapter 3.4.2 --- Birth weight (< 2.5kg vs > 2.5kg) --- p.P.41 / Chapter 3.4.3 --- Children with vs without current wheeze --- p.P.43 / Chapter 3.4.4 --- Children with vs without history of asthma ever --- p.P.44 / Chapter 3.4.5 --- Children with vs without recent respiratory tract infections (RTIs) --- p.P.45 / Chapter 3.5 --- The test-retest reliability --- p.P.47 / Chapter 3.6 --- "Relationship between lung function parameters and demographic, early-life, anthropometric and environmental factors in subjects who satisfied both health and ATS/ERS criteria in our research phase" --- p.P.50 / Chapter 3.6.1 --- Demographic factors --- p.P.51 / Chapter 3.6.2 --- Early-life factors --- p.P.53 / Chapter 3.6.3 --- Anthropometric factors --- p.P.56 / Chapter 3.6.4 --- Environmental factors --- p.P.57 / Chapter 3.7 --- Reference standards for incentive spirometry: Reference equations and normograms --- p.P.59 / Chapter Chapter 4: --- Discussions --- p.P.76 / Chapter 4.1 --- Pioneering incentive spirometry in Hong Kong preschoolers: Training and research phases --- p.P.77 / Chapter 4.2 --- Participants and non-participants in the research phase --- p.P.79 / Chapter 4.3 --- Subjects who succeed and failed to give acceptable maneuvers which meet ATS/ERS standards in the research phase --- p.P.81 / Chapter 4.4 --- "The relationship between demographic, anthropometric and environmental factors and spirometric parameters in local young children" --- p.P.84 / Chapter 4.41 --- Environmental tobacco smoke exposure and maternal smoking --- p.P.85 / Chapter 4.42 --- Place of birth --- p.P.87 / Chapter 4.43 --- Obesity and underweight --- p.P.89 / Chapter 4.44 --- Breastfeeding practice --- p.P.91 / Chapter 4.45 --- "Birth factors: mode of delivery, birth weight and gestation birth age" --- p.P.92 / Chapter 4.46 --- "Indoor environment: pets, moulds and others" --- p.P.94 / Chapter 4.5 --- Evaluation of the test-retest reliability --- p.P.95 / Chapter 4.6 --- The relationship between the health criteria and spirometric parameters in local young children --- p.P.96 / Chapter 4.7 --- The spirometric reference standards in Chinese preschool children in Hong Kong: Comparisons with published findings in different ethnic groups --- p.P.98 / Chapter 4.8 --- Drawbacks and limitations of this study --- p.P.105 / Chapter 4.9 --- Future research directions --- p.P.110 / Chapter Chapter 5: --- Conclusions --- p.P.111 / References --- p.P.112 / Appendices --- p.P.126 / Chapter Appendix I: --- Invitation letter --- p.P.127 / Chapter Appendix II: --- Reply form --- p.P.129 / Chapter Appendix III: --- Consent --- p.P.130 / Chapter Appendix IV: --- ISAAC questionnaire --- p.P.134 / Chapter Appendix V: --- Subject report --- p.P.163

Introdução: Já se sabe que as alterações na atuação da força da gravidade promovidas pela mudança de postura, influenciam os volumes e capacidades pulmonares, mas o comportamento das propriedades elásticas e plásticas do pulmão ainda não está bem esclarecido na literatura. Objetivo: Avaliar a resistência do sistema respiratório em sujeitos eutróficos e obesos nos diferentes decúbitos. Métodos: Os participantes foram alocados nos diferentes grupos, de acordo com o índice de massa corpórea (IMC Kg/m2 ), sendo eles: 18-25, 25-29, 30-39, 40-49 e >50. As posições foram avaliadas pelo Sistema de Oscilometria de Impulso (IOS) em ordem aleatória: sentada (Se), supina (Su) e decúbitos laterais, esquerdo (DLE) e direito (DLD), sendo obtidos os seguintes parâmetros: resistências total, central e periférica, reatância e frequência de ressonância. A espirometria foi realizada em seguida para a análise das seguintes variáveis: capacidade vital forçada, volume expiratório forçado no primeiro segundo, a relação VEF1/CVF e fluxo expiratório forçado médio. Resultados: Foram recrutados 110 voluntários, 36 com IMC de 18 a 25 Kg/m2 (26,8 anos; 21,7 Kg/m2 ), 19 com IMC de 25 a 29 Kg/m2 (26,1 anos; 26,6 Kg/m2 ), 21 com IMC de 30 a 39 Kg/m2 (30 anos; 34,5 Kg/m2 ), 21 com IMC de 40 a 49 Kg/m2 (35,4anos; 45 Kg/m2 ) e 13 com IMC>50 Kg/m2 (35,5 anos; 54,2Kg/m2 ). Não foram detectados distúrbios ventilatórios pela espirometria (médias acima de 80% do previsto). Os grupos começaram a se diferenciar a partir da faixa de 30-39 Kg/m2 , houve diferenças importantes entre os indivíduos com IMC>50 e 40-49 com aqueles com IMC<25 e 25-29 principalmente em vias periféricas (p<0,0001). A posição supina apresentou maiores valores de resistência para todos os grupos. Essas diferenças frente às mudanças de decúbito são mais frequentes nas faixas de IMC menores (<25 a 29 Kg/m2 ). Conclusão: Há maior impedância do sistema respiratório em sujeitos obesos, com maior contribuição da resistência periférica, porém com menores variações relacionadas à mudança de posição em comparação aos sujeitos eutróficos. / Background: It is known that changes in gravity force action, promoted by change of posture, influence volumes and capacities lung, but the behavior of lung elastic and plastic properties, has not yet well clarified in literature. Aim: To evaluate the effect of different positions on respiratory system resistance. Methods: Participants were allocated to different groups, according to the body mass index (BMI Kg/m2 ). The positions were evaluated by Impulse Oscillometry System (IOS) in a random order: seated (Se), supine (Su), left lateral (LL) or right lateral decubitus (RL) and following parameters was obtained: total, central and peripheral resistance, reactance and resonant frequency. Spirometry was then performed to analyze the following variables: forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC and mean forced expiratory flow (FEF25-75%). Results: A total of 110 volunteers were recruited, 36 with BMI<25 kg/m2 (26.8 years, 21.7 kg/m2 ), 19 with BMI between 25-29kg/m2 (26.1 years, 26.6 kg/m2 ), 21 with BMI between 30-39 kg/m2 (30 years, 34.5 kg/m2 ), 21 with BMI between 40-49 kg/m2 (35.4 years, 45 kg/m2 ) and 13 with BMI> 50 kg/m2 (35.5 years, 54.2 kg/m2 ). No ventilatory disturbances were detected by spirometry, all higher than predicted (80%). The groups began to differentiate from the range of 30-39 kg/m 2 , there were important differences between individuals with BMI>50 and 40-49 with those with BMI <25 and 25-29, mainly in peripheral pathways (p<0.0001). The supine position presented higher resistance values for all groups. These differences compared to changes in decubitus are more frequent in the lower BMI ranges (<25 to 29 kg/m 2 ). It was also observed that overweight individuals tend to follow the same pattern as those with BMI within normal range. Conclusion: The respiratory impedance is higher in obese than eutrophic subjects, with more contribution of peripheral resistance, but with smaller variations related to position change when compared to eutrophic ones.

Orientador: Daniele Cristina Cataneo / Banca: Suzana Erico Tanni / Banca: Karla Luciana Magnani / Resumo: A Doença de refluxo gastroesofágico é uma afecção muito comum. Atualmente, o tratamento cirúrgico videolaparoscópico tem sido amplamente empregado. Porém, apesar de ser uma técnica minimamente invasiva, pode acarretar uma série de alterações pulmonares importantes. Analisar as alterações funcionais respiratórias em indivíduos submetidos à válvula anti-refluxo videolaparoscópica. Foram avaliados, pela equipe do Hospital Estadual Bauru, no período de março de 2009 até maio de 2010, todos os pacientes com indicação cirúrgica. No período pré-operatório todos foram submetidos à anamnese, espirometria, medida do índice diafragmático, ventilometria, manovacuometria, pico de fluxo expiratório, teste de caminhada de 6 minutos e teste de escada. Todos os testes foram repetidos no primeiro, segundo, quinto e trigésimo pós-operatórios. Somente o teste de escada não foi repetido no primeiro pós-operatório. Foi avaliada em cada pós-operatório a escala analógica de dor, e a escala de Borg foi aplicada após os testes dinâmicos. Foram avaliados 32 pacientes, sendo 59% mulheres. A média da idade e do IMC foi de, respectivamente, 44,4±10,9 anos e 28,4±4,8 kg/m2. A amostra foi formada por 75% de não tabagistas, 6% de tabagistas e 19% de ex-tabagistas. Não houve qualquer caso de complicação pós-operatória. O VEF1, CVF, VVM e o PFE apresentaram queda significativa no PO1 e PO2, voltado aos valores pré no PO5. A PImáx e PEmáx apresentaram queda significativa no PO1, mantendo-se no PO2 ainda baixas, mas sem significância estatística com o pré, sendo que no PO5 seus valores já eram superiores aos do PO1 e semelhantes ao pré. O VE teve incremento estatisticamente significativo no PO2, ficando nos outros momentos em valores intermediários entre os valores PRÉ e PO2, enquanto a f teve acréscimo estatisticamente significante no PO1e nos outros momentos... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Gastroesophageal reflux disease is a very common condition. Currently, the laparoscopic surgical treatment has been widely used. However, despite being a minimally invasive technique, it may lead to a series of major pulmonary changes. Evaluate changes in respiratory function in patients who underwent laparoscopic anti-reflux valve. All patients with surgical indications were evaluated by the team of Bauru State Hospital, from March 2009 until May 2010. In the preoperative period all patients underwent history taking, spirometry, measurement of diaphragmatic index, respirometry, manometer, expiratory peak flow, 6-minute walking test and stairclimbing. All the tests were repeated in the first, second, fifth and thirtieth postoperative days. Only the stair climbing test was not repeated in the first postoperative day. It was assessed at each postoperative day the pain analog scale and the Borg scale was applied after the dynamic tests. We evaluated 32 patients, 59% women. The mean age and BMI was respectively 44.4 ± 10.9 years and 28.4 ± 4.8 kg/m2. The sample comprised 75% of nonsmokers, 6% of smokers and 19% of former smokers. There was no case of postoperative complication. FEV1, FVC, MVV and EPF showed significant decrease in PO2 and PO1, and it returned to baseline levels in PO5. The MIP and MEP showed a significant drop in the PO1, PO2 remaining at still low, but without statistical significance with the PRE, while in PO5 their values were already higher than PO1, and similar to the PRE. The MV had statistically significant increase in PO2, presenting at other times intermediate values between PRE and PO2, whereas the f had statistically significant increase in PO1 and presenting at other moments intermediate values to PRE and PO2. The TV and ID did not differ significantly at any time. The distance in 6MWT showed a significant drop in the PO1, and PO2. In PO5 there was no statistical... (Complete abstract click electronic access below) / Mestre

Typescript (photocopy). / Digitized by Kansas Correctional Industries

No description available.

Lung function depends on the expansion and contraction of lung tissue during the respiratory cycle. The measurement of regional pulmonary function is of great interest and importance since many lung diseases can cause changes in biomechanical or material properties. It is also significant to study the radiation-induced changes in pulmonary function following radiation therapy. In this thesis, we propose a technique that uses four-dimensional (3D+time) CT imaging (4DCT), 3D non-rigid image registration to estimate regional lung function. Lung images reconstructed at different inflation levels are analyzed for dynamic lung function development during a breath cycle. We demonstrate local pulmonary function can be reproducibly measured using 4DCT in human subjects prior to RT. The image registration accuracy is validated using semi-automatic anatomic landmark picking system. The major contributions of this thesis include: 1) demonstrating the robustness and reproducibility of regional pulmonary function measurement using 4DCT in both sheep and human subjects, 2) developing approaches to improve the measurement reproducibility by dynamic lung volume matching and Jacobian normalization, 3) development and comparison four cubic metrics for reproducibility analysis, 4) research on time-varying lung ventilation in different breathing phases in both sheep and human subjects. Our contributions in this thesis are useful for diagnosis and assessment of lung diseases, useful for qualifying radiation induced changes in pulmonary function in irradiated and non-irradiated lung tissue.

The human immunodeficiency virus (HIV)-1 can compromise pulmonary function at all stages of the disease. The present study examined whether there were differences in resting and exercising pulmonary function among sedentary, resistance-trained and aerobically-trained, early symptomatic, HIV-1+ men. Forty five subjects, 15 per group, were enrolled. An analysis of variance (ANOVA) showed differences in demographics for age [F (2, 42) = 5.14, p<0.01)], weight [F (2, 42) = 4.84, p<0.01)], body mass index [F (2, 42) = 9.50, p<0.01)] and average years HIV-1+ [F (2, 42) = 4.78, p<0.01)]. A multiple analysis of covariance (MANCOVA) showed differences in resting pulmonary function [F (8, 72) = 7.164, P = 0.01]. Univariate ANOVA's and Bonferroni post-hoc comparisons showed the aerobically-trained group had higher forced expiratory volume in one second (FEV1) than the resistance-trained and sedentary groups (p<0.05 and p<0.01, respectively), higher forced vital capacity (FVC) (p<0.01, for both), higher maximum voluntary ventilation (p<0.01, for both) and higher FEV1/FVC ratios than the sedentary group only (p<0.01). The resistance-trained group also showed higher FEV1 (p<0.01) and FEV1/FVC (p<0.01) than the sedentary group. For exercising pulmonary function, significant differences in our MANCOVA were found [F (12, 68) = 12.73, P = 0.001]. Univariate ANOVA's and Bonferroni post-hoc comparisons showed that the aerobically-trained group had higher dyspnea index than the resistance-trained and sedentary groups (p<0.01 and p<0.05, respectively), higher ventilatory efficiency (RR/VE max) than the resistance-trained and sedentary groups (p<0.05 and p<0.01, respectively), higher maximum minute ventilation (VE max) (p<0.01, for both), higher peak oxygen consumption (peak VO2) (p<0.01, for both) and lower dead space (VD/VT) (p<0.01, for both). The resistance-trained group also showed higher peak VO2 (p<0.01), lower VD/VT (p<0.01) and lower RR/VE max (p<0.01) than the sedentary group. Results suggest that aerobically-trained, and to a lesser extent, resistance-trained seropositives possessed superior resting and exercising pulmonary function compared to sedentary seropositive males.