Pulsed Detonation Engines (PDEs) have the potential to revolutionize fight by better utilizing the chemical energy content of reactive fuel/air mixtures over conventional combustion processes. Combustion by a super-sonic detonation wave results in a significant increase in pressure in addition to an increase in temperature. In order to harness this pressure increase and achieve a high power density, it is desirable to operate PDEs at high frequency. The process of detonation initiation impacts operating frequency by dictating the length of the chamber and contributing to the overall cycle time. Therefore a key challenge in the development of a practical PDEs is the requirement to rapidly initiate a detonation in hydrocarbon-air mixtures. This thesis evaluates the influence of spark energy and airflow velocity on this challenging initiation process. The influence of spark energy, number of sparks and airflow velocity on Deflagration-to-Detonation Transition (DDT) was studied during cyclic operation of a small-scale PDE at the General Electric Global Research Center. Experiments were conducted in a 50 mm square transitioning to cylindrical channel PDE with optical access operating with stoichiometric ethylene-air mixture. Total spark energy was varied from 250 mJ to 4 J and was distributed between one and four spark plugs located in the same axial location. Initial flame acceleration was imaged using high-speed shadowgraph and was characterized by the time to reach 20 cm from the spark plug. Measurements of detonation wave velocity and emergence time, the time it takes the detonation wave to exit the tube, was measured using dynamic pressure transducers and ionization probes. It was found that the flame front spread was faster at higher spark energies and with more spark locations. Initial flame acceleration was 16% faster for the 4-spark, 4 J case when compared to the baseline 1-spark, 1 J case. When looking at the effect of airflow on the influence of spark energy, it was found that airflow had a larger effect on emergence time at high energies, versus energies less than 1 J. Finally, for a selected case of 0.25 J spark energy and 4 sparks, the velocity of the fuel-air mixture during fill was found to have a varying influence on detonation initiation and emergence time.