Os fatores que possam promover e incrementar a osseointegração, ou prejudicar o processo biológico, aumentando o índice de falhas, têm sido cada vez mais investigados com o objetivo de ampliar indicações e as taxas de sobrevivência dos implantes dentais assim como controlar fatores adversos. O objetivo desta tese foi identificar, analisar e sintetizar as evidências científicas quanto a influência das estatinas, do envelhecimento e da experiência do cirurgião no processo osseointegração e na sobrevivência de implantes dentais. Este volume apresenta um compilado de três revisões sistemáticas orientadas pelas recomendações PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). O processo de revisão foi realizado por meio de uma busca sistemática em cinco bases de dados eletrônicas (PubMed, Scopus, Web of Science, Embase e Cochrane Library), além de busca manual nas referências bibliográficas dos estudos incluídos. A meta-análise, quando cabível, foi realizada com o auxílio do software Review Manager (RevMan, Versão 5.3). O grau de heterogeneidade entre os estudos foi verificado por meio do teste Q de Cochran e I2. O viés das publicações foi avaliado com o auxílio das escalas Newcasttle-Ottawa e Cochrane Collaboration\'s Tool. A síntese dos dados permitiu a publicação de três artigos científicos dispostos nesta tese. / Factors that may promote and enhance osseointegration, or impair the biological process, have been increasingly investigated in order to expand the indications and survival rates of dental implants and control the adverse factors. The aim of this thesis is to identify and summarize the scientific evidence of statins, ageing and surgeon related factors that can influence osseointegration and survival of dental implants. This volume presents a compilation of three systematic reviews structured by PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The review process was carried out through a systematic search in five electronic databases (PubMed, Scopus, Web of Science, Embase and Cochrane Library) and bibliographical references of the included studies. Meta-analyses, when appropriate, were performed using the software Review Manager (RevMan version 5.3). The degree of heterogeneity in the studies was verified by Q Cochran test and I2. The bias of the publications was assessed with the assistance of Newcastle-Ottawa Scale and Cochrane Collaboration Tool\'s. The synthesis of the data was included in three papers prepared for this thesis.

Networks have been widely used to represent and analyze a system of connected elements. Online social media networks, as a result of the expansion of the Internet and increased need of communication, have become an increasingly important part of people's lives. This thesis focuses on the statistical analysis of network data motivated by problems in online social media. It discusses problems arising from both explicit network data and implicit network data. Explicit network data are data where network structures are observable, implicit network data are those that do not have a network structure but occur under the influence of an underlying network. For the explicit network data analysis, we develop a novel method of recovering a fundamental characteristic -- network degree distributions -- under sampling. We formulate the problem of estimating degree distribution as an inverse problem. We show that this problem is ill-conditioned for many sampling methods in practice, and accordingly propose a constrained, penalized weighted least-squares approach to solve this problem. We demonstrate the ability of our method to accurately reconstruct the degree distributions from simulated network data and real world social network data. We also propose practical usage of the estimates relevant to marketing and advertising. For the implicit network data analysis, we look at review data from the popular review websites. Motivated by articles from the popular press and the research community which publicized that the average rating for top review sites is above 4 out of 5 stars, we study the phenomena of review rating trends and convergence using restaurant review data from TripAdvisor. We analyze the trend on different levels -- a rough analysis of the characteristics of the ratings, and a subtler statistical modeling with ordinal logistic regressions. Taking into account the implicit network underlying the review data, we suggest the upward trend observed in restaurant review ratings may be explained by social influence on an individual's perception of qualities. We use the intensity of review postings as an indicator of how popular a restaurant is and to test to what extent the increase in review intensity explains increases in average rating. After that, we consider a more nuanced approach to the joint modeling of ratings and review intensity which would allow for interaction between the two, rather than intensity serving only as an explanatory variable to ratings. Specifically, a state-space model is used to test the interaction between review intensity and review ratings.

Obtaining a building permit is an important step for any construction project. Whether it is for a new construction or a remodel job, the process involves a plan review performed by building officials. The purpose of this research was to explore ways in which Building Information Modeling (BIM) could be used to aid code officials during the plan review process. The objectives of the study were to determine if the level of detail in BIM was complete enough to allow a plan review to be perform accurately, to identify the extent to which architects are comfortable with using their models for the plan review, and to identify barriers to implementation. A case study was conducted where BIM was used to supplement the traditional 2D plans plan review process. Additionally, a survey was given to local architects to obtain their thoughts on using BIM in the plan review process. The research found that BIM has the potential of helping code officials visualize the project, extract information from objects, and allow them to have a better understanding of unique building features relationship to other building elements. Challenges of using BIM in the plan review process identified by architects included: the accuracy of the model, the level of detail modeled, legal implications, and ability of reviewers to use BIM.

yes / This systematic review of reviews aims to investigate how brief interventions (BIs) are defined, whether they increase physical activity, which factors influence their effectiveness, who they are effective for, and whether they are feasible and acceptable. We searched CINAHL, Cochrane database of systematic reviews, DARE, HTA database, EMBASE, MEDLINE, PsycINFO, Science Citation Index-Expanded and Social Sciences Citation Index, and Scottish Intercollegiate Guidelines Network from their inception until May 2015 to identify systematic reviews of the effectiveness of BIs aimed at promoting physical activity in adults, reporting a physical activity outcome and at least one BI that could be delivered in a primary care setting. A narrative synthesis was conducted. We identified three specific BI reviews and thirteen general reviews of physical activity interventions that met the inclusion criteria. The BI reviews reported varying definitions of BIs, only one of which specified a maximum duration of 30 min. BIs can increase self-reported physical activity in the short term, but there is insufficient evidence about their long-term impact, their impact on objectively measured physical activity, and about the factors that influence their effectiveness, feasibility and acceptability. Current definitions include BIs that are too long for primary care consultations. Practitioners, commissioners and policy makers should be aware of this when interpreting evidence about BIs, and future research should develop and evaluate very brief interventions (of 5 min or less) that could be delivered in a primary care consultation. / Citation sent on from Donna. Emailed Laura Lamming for final draft 16/03/2017 -sm

Review of Jones, R. L. & Wofford. B. E (2013). Woody Plants of Kentucky and Tennessee: The Complete Winter Guide to Their Identification and Use. Lexington, KY: The University Press of Kentucky. 224 pages. ISBN: 9780813142500

Review of Byerly, D. W. (2013). The Last Billion Years: A Geologic History of Tennessee. Knoxville: University of Tennessee Press. 212 pages. ISBN: 9781572339743

Review of Camp Redemption, by Raymond l. Atkins].

Review of Lambert, L. C., Jr. & Lambert, M. (2011). Up from These Hills: Memories of a Cherokee Boyhood. Lincoln: University of Nebraska Press. 197 pages. ISBN 978-0-8032-3536-6.

Book Review of Wood, A. L. (Ed.). (2011). The New Encyclopedia of Southern Culture. Volume 19: Violence. Chapel Hill: University of North Carolina Press. 368 pages. ISBN: 9780807872161

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