Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-01-27T19:01:45Z No. of bitstreams: 1 AndersonNicollyFernandesDaCosta_DISSERT.pdf: 1318772 bytes, checksum: 2e4252b773f8c3dce141ad64162615d9 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-02-02T21:38:50Z (GMT) No. of bitstreams: 1 AndersonNicollyFernandesDaCosta_DISSERT.pdf: 1318772 bytes, checksum: 2e4252b773f8c3dce141ad64162615d9 (MD5) / Made available in DSpace on 2016-02-02T21:38:50Z (GMT). No. of bitstreams: 1 AndersonNicollyFernandesDaCosta_DISSERT.pdf: 1318772 bytes, checksum: 2e4252b773f8c3dce141ad64162615d9 (MD5) Previous issue date: 2015-01-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / A mucosite peri-implantar ? uma inflama??o da mucosa ao redor do implante em resposta ao ac?mulo do biofilme. Existem diversos protocolos para o tratamento da mucosite peri-implantar, mas ainda n?o existem evid?ncias consistentes para escolha de um protocolo. Em virtude disso, esta pesquisa objetiva verificar a efic?cia longitudinal do uso da clorexidina a 0,12% como um adjuvante ? terapia full-mouth desinfection da mucosite peri-implantar. Trinta e oito pacientes previamente diagnosticados com mucosite peri-implantar foram distribu?dos aleatoriamente em dois grupos. Todos os pacientes receberam o tratamento n?o-cir?rgico associado (teste, n = 22) ou n?o (controle, n = 16) a clorexidina a 0,12% al?m de instru??o de higiene bucal individualizada. Os pacientes foram avaliados no baseline, 3, 6, 12 e 18 meses quanto aos ?ndices de placa vis?vel e sangramento gengival, profundidade de sondagem e sangramento ? sondagem. Os dados foram analisados estatisticamente pelos testes de Friedman, Wilcoxon, Mann-Whitney, Correla??o de Spearman e Qui-quadrado, utilizando um ? de 5%. A an?lise intragrupo mostrou que ambos os tratamentos propostos foram eficazes na redu??o dos ?ndices de placa vis?vel e sangramento gengival, profundidade de sondagem e sangramento ? sondagem (p<0,05). No entanto, nenhum dos grupos alcan?ou resultados superiores em rela??o ao outro. Conclui-se que a terapia mec?nica por si s? ? eficaz na redu??o dos par?metros cl?nicos analisados e que, como os grupos tornaram-se iguais pelo fato do efeito da clorexidina n?o mais existir, a terapia de suporte periimplantar fora eficiente em reduzir os ?ndices de placa vis?vel e sangramento gengival, profundidade de sondagem e sangramento ? sondagem ao final do estudo / The peri-implant mucositis is an inflammation of the mucosa around the implant in response to the accumulation of biofilm. There are many protocols for the treatment of peri-implant mucositis, but are not consistent evidence for selecting a protocol. As a result, this research has evaluated the longitudinal effectiveness of use of chlorhexidine 0.12% as an adjunct to full-mouth desinfection therapy peri-implant mucositis. Thirty-eight patients previously diagnosed with peri-implant mucositis were randomized into two groups. All patients received non-surgical treatment associated (test, n = 22) or not (control, n = 16) to 0.12% chlorhexidine plus individualized oral hygiene instruction. Patients were evaluated at baseline, 3, 6, 12 and 18 months as the visible plaque index, gingival bleeding, probing depth and bleeding on probing. Data were statistically analyzed by Friedman, Wilcoxon and Mann-Whitney test, Spearman correlation and chi-square test, using a ? 5%. The intra-group analysis showed that both the treatments were effective in reducing visible plaque indices, gingival bleeding, probing depths and bleeding on probing (p <0.05). However, none of the groups achieved superior results relative to each other. It was concluded that the mechanical therapy alone is effective in reducing the clinical parameters analyzed and, as groups become equal because the effect of chlorhexidine not exist, supportive therapy peri-implant was effective in reducing the visible plaque index, gingival bleeding, probing depth and bleeding on probing at the end of the study.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2018-04-02T15:39:52Z No. of bitstreams: 1 IsraelAlexandreDeAraujoSena_DISSERT.pdf: 1066452 bytes, checksum: 0db686fe8e7a09cfb316d9c4ce792350 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2018-04-06T16:43:08Z (GMT) No. of bitstreams: 1 IsraelAlexandreDeAraujoSena_DISSERT.pdf: 1066452 bytes, checksum: 0db686fe8e7a09cfb316d9c4ce792350 (MD5) / Made available in DSpace on 2018-04-06T16:43:08Z (GMT). No. of bitstreams: 1 IsraelAlexandreDeAraujoSena_DISSERT.pdf: 1066452 bytes, checksum: 0db686fe8e7a09cfb316d9c4ce792350 (MD5) Previous issue date: 2017-12-19 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A Cloro-alum?nio ftalocianina (AlClFc), como droga fotossensibilizadora, tem demonstrado resultados favor?veis em estudos cl?nicos e laboratoriais, no entanto ainda n?o h? ensaios cl?nicos que avaliem sua aplica??o na terapia fotodin?mica antimicrobiana (TFDA) em periodontite cr?nica (PC). Assim, o objetivo deste estudo foi avaliar o efeito da TFDA com AlClFc adjuvante ? raspagem e alisamento corono-radicular (RACR) nos par?metros cl?nicos periodontais de pacientes com PC. O estudo caracterizou-se por um ensaio cl?nico boca dividida, randomizado, duplo cego, longitudinal e prospectivo. Cinquenta e quatro s?tios periodontais foram randomicamente distribu?dos em dois grupos: 27 no grupo teste (RACR + TFDA) e 27 no controle (RACR). A RACR foi realizada em sess?o ?nica e os par?metros cl?nicos periodontais de ?ndice de placa vis?vel (IPV), ?ndice de sangramento ? sondagem (ISS), profundidade de sondagem (PS) e n?vel de inser??o cl?nica (NIC) foram avaliados na linha base (T0) e ap?s 3 meses (T3) da TFDA. Os dados foram submetidos ? an?lise estat?stica pelos testes n?o-param?tricos de Wilcoxon e Mann-Whitney, ao n?vel de signific?ncia de 5%. Observou-se redu??o do ISS em ambos os grupos de tratamento, com TFDA adjuvante (p = 0,003) e somente RACR (p = 0,001), entre T0 e T3. Na compara??o intergrupos n?o houve diferen?a estatisticamente significativa. Verificou-se redu??o da PS e ganho de inser??o cl?nica para ambos os grupos de tratamento (p<0,05) ap?s 3 meses da terapia. Na compara??o intergrupos n?o houve diferen?a estatisticamente significativa (p>0,05) em nenhum dos tempos analisados. A TFDA com AlClFc, adjuvante ? RACR, n?o proporcionou benef?cios adicionais na redu??o da profundidade de sondagem e ganho de inser??o cl?nica. / Chloro-aluminum phthalocyanine (AlClPc), as a photosensitizing drug, has shown favorable results in clinical and laboratory studies; however, there are no clinical trials evaluating its application in antimicrobial photodynamic therapy (PDTa) in chronic periodontitis (CP). Thus, the objective of this study was to evaluate the effect of adjuvant PDTa with AlClPc on scaling and root planing (SRP) in periodontal clinical parameters of patients with CP. The study was characterized as split-mouth randomized clinical trial, double-blind, longitudinal and prospective. Fifty-four periodontal sites were randomly distributed into two groups: 27 in the test group (SRP + PDTa) and 27 in the control group (SRP). The SRP was performed in a single session and clinical periodontal parameters of plaque index (PI), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were assessed at the baseline ( T0) and after 3 months (T3) of the PDTa. Data were submitted to statistical analysis by the non-parametric Wilcoxon and Mann-Whitney tests, at a significance level of 5%. There was a reduction in the BOP in both treatment groups, with adjuvant PDTa (p = 0.003) and only SRP (p = 0.001), between T0 and T3. In the inter-group comparison there was no statistically significant difference. PD reduction and clinical insertion gain were observed for both treatment groups (p <0.05) after 3 months of therapy. In the inter-group comparison there was no statistically significant difference (p> 0.05) in any of the times analyzed. PDTa with AlClPc, adjuvant to RACR, did not provide additional benefits in reducing depth of probing and gain of clinical insertion.