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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

The role of wear particles in prosthesis loosening /

Howie, Donald William. January 1987 (has links) (PDF)
Thesis (Ph. D.)--University of Adelaide, 1987. / Includes bibliographical references (leaves 196-251).

The interrelationship of epithelial rests of Malassez with orthodontic root resorption and repair in man /

Brice, Garth Loyola. January 1988 (has links) (PDF)
Thesis (M.D.S.)--University of Adelaide, Dept. of Dentistry, 1989? / "Addenda" [i.e. Errata] on fly-leaf. Includes bibliographical references (leaves 159-176).

Das Vorkommen von Wurzellosigkeit und ausgedehnten Resorptionen an bleibenden Zähnen und persistierenden Milchzähnen, Ursachen und Therapie

Christmann, Erich, January 1933 (has links)
Thesis (doctoral)--Munich, 1933. / Includes bibliographical references (p. [18]).

Eigenschaften ungefüllter und gefüllter Polylactide im Hinblick auf ihr Potenzial für resorbierbare Implantatwerkstoffe /

Bauer, Jochen. January 2003 (has links)
Thesis (doctoral)--Universiẗat, Erlangen, Nürnberg, 2003.

Das Vorkommen von Wurzellosigkeit und ausgedehnten Resorptionen an bleibenden Zähnen und persistierenden Milchzähnen, Ursachen und Therapie

Christmann, Erich, January 1933 (has links)
Thesis (doctoral)--Munich, 1933. / Includes bibliographical references (p. [18]).

The dento-alveolar complex /

Symons, Anne L. January 2004 (has links) (PDF)
Thesis (DDSc) - University of Queensland, 2003. / Includes bibliography.

Three dimensional dynamic hypoelastic remodeling in the proximal femur /

Negus, Charles Hugh. January 2005 (has links)
Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2005. / Vita. Appendix A: "C program listing." Includes bibliographical references (leaves 201-211).

Clast cell activity in a model of aseptic root resorption / Craig William Dreyer.

Dreyer, Craig William January 2002 (has links)
Includes bibliographical references (leaves 355-403) / 403 leaves : plates (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dental School, 2002

Studies into the mechanism of action of clodronate

Frith, Julie C. January 1998 (has links)
No description available.

Elucidating Differences in Osteoclast Activation Mechanisms: Looking for Targets to Prevent Pathological Bone Resorption

Trebec-Reynolds, Diana Patricia 01 September 2010 (has links)
Inflammatory bone diseases like rheumatoid arthritis and periodontal disease lead to increased bone loss in the inflamed areas. The multinucleated bone resorbing cells, the osteoclasts, present in these diseases are larger than normal, and these larger osteoclasts (10+ nuclei) resorb more bone and more often than smaller osteoclasts (2-5 nuclei). Thus, the focus of this thesis was to determine if there are differences in mechanisms of osteoclast activation between large and small osteoclasts. Experiments using authentic rabbit osteoclasts and RAW 264.7-derived osteoclasts revealed differences in the expression of a number of activating factors; with large osteoclasts expressing higher levels of activating receptors (RANK, IL-1RI, TNFR1 and integrins αv and β3), as well as enzymes involved in cellular resorption, while small osteoclasts expressed higher levels of an alleged fusion receptor and the inhibitory receptor, IL-1RII. Further studies revealed that large osteoclasts more readily responded to stimulation by IL-1 compared to small osteoclasts and at lower concentrations suggesting this is a result of their higher expression of activating receptors. Differences in responses to the IL-1 isoforms, IL-1α and IL-1β, were also seen in large osteoclasts: IL-1α generated more large osteoclasts over the course of differentiation, while IL-1β induced changes in cell morphology and in the induction of integrin β3 phosphorylation. These observations suggested that differences in osteoclast responses are induced by IL-1α and IL-1β and it led to the hypothesis that there are differences in signaling between large and small osteoclasts. To elucidate differences in signaling mechanisms a signaling pathway microarray was used which revealed higher expression of Vegfa in large compared to small osteoclasts. Osteoclast differentiation with RANKL increased Vegfa gene expression in a time-dependent manner and VEGF-A secretion was elevated in populations enriched for large osteoclasts. Furthermore, mechanistic studies with inhibitors of transcription factors involved in differentiation revealed that RANKL-mediated Vegfa expression in large osteoclasts was regulated by the NF-κB pathway via induction of Hif1α. These results support the hypothesis that signaling differences exist between large and small osteoclasts and implicates VEGF-A in osteoclast hyperactivity in inflammatory conditions.

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