A set of equations describing the motion of a naturally curved and twisted slender elastic rod is determined in this thesis. In particular, a study of the vibration of a helical spring is made, and the natural frequencies from the theory presented are compared with those from a simpler theory. Comparison of the two theories shows that the simpler theory is valid for most springs. The simpler theory is then used to show how the natural frequencies for a helical spring can be obtained when the spring is subjected to any boundary conditions. Finally, an analytical and experimental study of the vibration of a helical spring clamped at both ends is made in order to investigate the validity of the theory presented. / Thesis / Master of Engineering (MEngr)

This file is officially titled as a project. This is Part B in connection with another project by the same author, titled "Part A: Adjuster Rod Design in a CANDU Reactor and Flux Distributions Due to an Arbitrary Source of Neutrons."http://hdl.handle.net/11375/15387 / In this report, the effectiveness of a proposed Shutoff Rod System a CANDU Reactor was investigated. A full core simulation was done, to study the neutronic power transient following a change in coolant conditions. / Thesis / Master of Engineering (ME)

This thesis deals with the production of a continuous rod of non-uniform properties which is formed by wrapping fibers with a thin membrane. This rod is driven axially and cut into segments. Measurements of pressure, temperature, axial force, axial velocity, horizontal and vertical displacements were taken of the rod during normal operating conditions at various speeds. The time signal for these tests were converted to the frequency domain through the use of a Fast Fourier Transform (FFT). The data was then examined to determine the inputs into the rod from various components of the rod producing machine. The results of the experiments show that the machine has inputs in several location along the production line. It also shows that changing components of the machine based on their frequency response may be beneficial in minimizing the number of stoppages in the production of the rod. This investigation into the dynamics of rod production shows that there is a potential for significant gains in production by altering certain components of the production machines. This report also offers a future test procedure that should help to better explain the rod’s motion and thus may lead to more efficient production. / Master of Science

The thesis treats roll pass design in wire rod rolling of stainless steel for sequences and series built up by two-symmetrical grooves. It is focused on predicting rolling flexibility, also called working range, as well as product quality. For analysing the flexibility a computer program has been developed. The minimum and maximum roll gap and corresponding bar areas for series of grooves including "oval", "round", "false round", "square" and "diamond" shapes are calculated. Six pass designs used in Swedish mills are analysed. Full-scale rolling is compared with laboratory experiments for the square-oval and false round (round)-oval series. The false round-oval series offers the largest working range and that the flexibility is smaller for pass sequences designed for high reductions. The false round-oval series are also acknowledged as a series for high quality steels and are usually better than the square-oval series having a tendency for defect formation. The thesis also includes high-speed rolling of wire rod in blocks. Here interstand tensions are utilised in order to keep the process stable. For obtaining the required dimensional tolerances of the product they are kept as low as possible. However interstand tensions could be used in order to increase the working range and move the product range towards smaller wire cross sections. For analysing this possibility, a narrow spread technology is utilised. At present time a practical problem is referred to the fixed gearings in the common blocks, which require a certain and given level of interstand tensions and corresponding reductions. This problem can however be solved by means of new block design and modern process control technology. Roll stands can be separately driven and controlled at very high speeds. Thus the eight stand blocks can be subdivided into four plus four passes blocks with a cooling line between enabling also higher productivity without violating the product quality because defect formations caused by a too high rolling temperature. The true working range of a series for a specific steel grade is however not only dependent on the possible spectrum of wire dimensions that can be obtained but might also depend on its ability to decrease or eliminate defects such as surface cracks. Thus, the behaviour of artificial V-shaped cracks in the longitudinal direction has been investigated and compared for the square-oval and false round (round)-oval series mentioned above. In agreement with other research works it was established that efficient rolling conditions for reducing the cracks are obtained when the cracks open up at the same time as their depth is reduced. If the V-shaped crack is closed by contact between its oxidized side surfaces the rolling schedule is not optimal for getting a high quality product. A deeper understanding of the experimental results was obtained by means of an FE-analysis

<p>The thesis treats roll pass design in wire rod rolling of stainless steel for sequences and series built up by two-symmetrical grooves. It is focused on predicting rolling flexibility, also called working range, as well as product quality. For analysing the flexibility a computer program has been developed. The minimum and maximum roll gap and corresponding bar areas for series of grooves including "oval", "round", "false round", "square" and "diamond" shapes are calculated. Six pass designs used in Swedish mills are analysed. Full-scale rolling is compared with laboratory experiments for the square-oval and false round (round)-oval series. The false round-oval series offers the largest working range and that the flexibility is smaller for pass sequences designed for high reductions. The false round-oval series are also acknowledged as a series for high quality steels and are usually better than the square-oval series having a tendency for defect formation. The thesis also includes high-speed rolling of wire rod in blocks. Here interstand tensions are utilised in order to keep the process stable. For obtaining the required dimensional tolerances of the product they are kept as low as possible. However interstand tensions could be used in order to increase the working range and move the product range towards smaller wire cross sections. For analysing this possibility, a narrow spread technology is utilised. At present time a practical problem is referred to the fixed gearings in the common blocks, which require a certain and given level of interstand tensions and corresponding reductions. This problem can however be solved by means of new block design and modern process control technology. Roll stands can be separately driven and controlled at very high speeds. Thus the eight stand blocks can be subdivided into four plus four passes blocks with a cooling line between enabling also higher productivity without violating the product quality because defect formations caused by a too high rolling temperature. The true working range of a series for a specific steel grade is however not only dependent on the possible spectrum of wire dimensions that can be obtained but might also depend on its ability to decrease or eliminate defects such as surface cracks. Thus, the behaviour of artificial V-shaped cracks in the longitudinal direction has been investigated and compared for the square-oval and false round (round)-oval series mentioned above. In agreement with other research works it was established that efficient rolling conditions for reducing the cracks are obtained when the cracks open up at the same time as their depth is reduced. If the V-shaped crack is closed by contact between its oxidized side surfaces the rolling schedule is not optimal for getting a high quality product. A deeper understanding of the experimental results was obtained by means of an FE-analysis</p>

Thesis (Ph. D.)--University of Alabama at Birmingham, 2008. / Title from first page of PDF file (viewed Feb. 12, 2009). Includes bibliographical references (p. 136-146).

Univerzita Karlova v Praze Filozofická fakulta Ústav pro dějiny umění Dějiny výtvarného umění - Obecná teorie a dějiny umění a kultury Erika O k r u h l i c o v á Parlerovská architektúra na západnom Slovensku The Parlerian Architecture in the Western Slovakia Disertační práce vedoucí práce - Prof. PhDr. Jiří Kuthan, DrSc., Dr. h. c. 2015 ABSTRAKT Dizertačná práca sa venuje parlerovskej architektúre na západnom Slovensku. Parlerovská architektúra, súvisiaca s priamou činnosťou rodu Parler, trvala približne od poslednej tretiny 14. storočia do polovice 15. storočia. Stavitelia, ktorí pokračovali v odkaze rodu Parler, stavali približne do záveru 15. storočia. Uvedená architektúra zahŕňa cirkevné stavby (kostoly, kaplnky), hrady (v rámci ktorých boli stavané aj kaplnky) a radničnú kaplnku. Stavby priamo, resp. sprostredkovane súvisia so staviteľskou činnosťou rodu Parler, ktorého člen Peter Parler, pôsobiaci predovšetkým v Prahe, uviedol do architektúry nové riešenia, uplatňované počas viacerých generácií staviteľov, aj členmi iných staviteľských rodov. Priama činnosť členov rodu Parler s menami Henrich ml., Václav a Janco je v práci preskúmaná z hľadiska pravdepodobnosti a hypotéz ich pôsobenia na západnom Slovensku. V stredoveku bola aj svetská architektúra úzko spojená s božským poslaním s odkazmi na...

This thesis is interested in isolation and identification of probiotic bacteria in three different probiotic products using polymerase chain reaction (PCR). DNA in quality suitable for PCR was isolated from crude lysates using three different types of magnetic microparticles and phenol extraction. Identification genera and species of probiotic bacteria was proven using genus and species specific PCRs. Results were in accordance with data presented by manufacturers.

This thesis concentrates on the design of crank-type mechanism of engine with elongated expansion. The main attention is paid to examination of the progress of kinematic quantities and inertial forces in mechanism. Further on in the thesis, the analysis of piston-rod stress is carried out and is compared to the piston-rod of standard engine. In the last part of the thesis, there is an evaluation of advantages and disadvantages of the proposed mechanism solution.

Retinitis Pigmentosa (RP) is an incurable inherited retinal degeneration affecting approximately 1 in 4,000 individuals globally. The aim of this dissertation was to identify drugs that can help patients suffering from the disease. To accomplish this goal, the zebrafish was utilized as a model for RP to perform <i>in vivo</i> drug screening. The zebrafish RP model expresses a human rhodopsin transgene which contains a premature stop codon at position 344 (<i>Tg</i>(<i>rho:Hsa.RH1_Q344X</i>)). This zebrafish model exhibits significant rod photoreceptor degeneration beginning at 7 days post fertilization (dpf). To assess the visual consequence of this rod degeneration the zebrafish behavior visual motor response (VMR) was assayed under scotopic conditions. The Q344X RP model larvae displayed a deficit in this VMR in response to a scotopic light offset. This deficit in behavior was utilized to perform a drug screen to identify compounds that could ameliorate the deficient Q344X VMR. The ENZO SCREEN-WELL® REDOX library was chosen to be screened since oxidative stress may increase RP progression in a non-specific manner. From this library, a β-blocker, carvedilol, was identified as a compound that improved the Q344X VMR behavior. This drug was also able to increase rod number in the Q344X retina. Carvedilol was shown to be capable of working directly on rods by demonstrating that the drug can signal through the adrenergic pathway in the rod-like human Y79 cell line. Since carvedilol is an FDA-approved drug, this screening paradigm was utilized to screen the Selleckchem FDA-approved library to identify more drugs that can potentially be repurposed to treat RP like carvedilol. Additionally, this scotopic VMR assay was used to demonstrate that it can identify behavioral deficits in the P23H RP model zebrafish<i> (Tg</i>(<i>rho:Hsa.RH1_P23H</i>)). This dissertation work provides a potential FDA-approved drug for RP treatment and sets the foundation for future drug screening to identify more drugs to treat different forms of RP.