<p>A digital microfluidic biochip (DMFB) is a device that digitizes fluidic samples into tiny droplets and operates chemical processes on a single chip. Movement control of droplets can be realized by using electrowetting-on-dielectric (EWOD) technology. DMFBs have high configurability, high sensitivity, low cost and reduced human error as well as a promising future in the applications of point-of-care medical diagnostic, and DNA sequencing. As the demands of scalability, configurability and portability increase, a new DMFB architecture called Microelectrode Dot Array (MEDA) has been introduced recently to allow configurable electrodes shape and more precise control of droplets.</p> <p>The objective of this work is to investigate a routing algorithm which can not only handle the routing problem for traditional DMFBs, but also be able to route different sizes of droplets and incorporate diagonal movements for MEDA. The proposed droplet routing algorithm is based on 3D-A* search algorithm. The simulation results show that the proposed algorithm can reduce the maximum latest arrival time, average latest arrival time and total number of used cells. By enabling channel-based routing in MEDA, the equivalent total number of used cells can be significantly reduced. Compared to all existing algorithms, the proposed algorithm can achieve so far the least average latest arrival time.</p>

An ad-hoc network is a packet radio network in which individual mobile nodes perform routing functions. Typically, an ad-hoc networking concept allows users wanting to communicate with each other while forming a temporary network, without any form of centralized administration. Each node participating in the network performs both the host and router function, and willing to forward packets for other nodes. For this purpose a routing protocol is needed. A novel approach utilizes the uniqueness of such a network i. e. distance, location and speed of the nodes, introducing a Distance Routing Effect Algorithm for Mobility (DREAM). The protocol uses the <i>distance effect</i> and the <i>mobility rate</i> as a means to assure routing accuracy. When data needs to be exchanged between two nodes, the directional algorithm sends messages in the recorded direction of the destination node, guaranteeing the delivery by following the direction. The improved algorithm suggested within this thesis project includes an additional parameter, direction of travel, as a means of determining the location of a destination node. When data needs to be exchanged between two nodes, the directional algorithm sends messages in the recorded direction of the destination node, guaranteeing the delivery by following the direction. The end result is an enhancement to the delivery ratio, of the sent to the received packet. This also allows the reduction in the number of control packets that need to be distributed, reducing the overall control overhead of the Improved Dream protocol.

The design of modern integrated circuits is overwhelmingly complicated due to the enormous number of cells in a typical modern circuit. To deal with this difficulty, the design procedure is broken down into a set of disjoint tasks. Circuit layout is the task that refers to the physical realization of a circuit from its functional description. In circuit layout, a connection-list called netlist of cells and nets is given. Placement and routing are subtasks associated with circuit layout and involve determining the geometric locations of the cells within the placement area and connecting cells sharing common nets. In performing the placement and the routing of the cells, minimum placement area, minimum delay and other performance constraints need to be observed. In this work, we propose and investigate new approaches to placement and routing problems. Specifically, for the placement subtask, we propose new convex programming formulations to estimate wirelength and force cells to spread within the placement area. As opposed to previous approaches, our approach is partitioning free and requires no hard constraints to achieve cell spreading within the placement area. The result of the global optimization of the new convex models is a global placement which is further improved using a Tabu search based iterative technique. The effectiveness, robustness and superiority of the approach are demonstrated on a set of nine benchmark industrial circuits. With regard to the routing subtask, we propose a hybrid methodology that combines Tabu search and Stochastic Evolution as a search engine in a new channel router. We also propose a new scheme based on Utility Theory for selecting and assigning nets to tracks in the channel. In this scheme, problem-domain information expressed in the form of utility functions is used to guide the search engine to explore the search space effectively. The effectiveness and robustness of the approach is demonstrated on five industrial benchmarks.

Less-Than-Truckload (LTL) carriers generally serve geographical regions that are more localized than the inter-city routes served by truckload carriers. That localization can lead to urban freight transportation routes that overlap. If trucks are traveling with less than full loads there may exist opportunities for carriers to collaborate over such routes. That is, Carrier A will also deliver one or more shipments of Carrier B. This will improve vehicle asset utilization and reduce asset-repositioning costs, and may also lead to reduced congestion and pollution in cities. We refer to the above coordination as “collaborative routing”. In our framework for collaboration, we also propose that carriers exchange goods at logistics platforms located at the entry point to a city. This is referred to as “entry-point collaboration”. One difficulty in collaboration is the lack of facilities to allow transfer of goods between carriers. We highlight that the reduction in pollution and congestion under our proposed framework will give the city government an incentive to support these initiatives by providing facilities. Further, our analysis has shown that contrary to the poor benefits reported by previous work on vehicle routing with transshipment, strategic location of transshipment facilities in urban areas may solve this problem and lead to large cost savings from transfer of loads between carriers. We also present a novel integrated three-phase solution method. Our first phase uses either a modified tabu search, or a guided local search, to solve the vehicle routing problems with time windows that result from entry-point collaboration. The preceding methods use a constraint programming engine for feasibility checks. The second phase uses a quad-tree search to locate facilities. Quad-tree search methods are popular in computer graphics, and for grid generation in fluid simulation. These methods are known to be efficient in partitioning a two-dimensional space for storage and computation. We use this efficiency to search a two-dimensional region and locate possible transshipment facilities. In phase three, we employ an integrated greedy local search method to build collaborative routes, using three new transshipment-specific moves for neighborhood definition. We utilize an optimization module within local search to combine multiple moves at each iteration, thereby taking efficient advantage of information from neighborhood exploration. Extensive computational tests are done on random data sets which represent a city such as Toronto. Sensitivity analysis is performed on important parameters to characterize the situations when collaboration will be beneficial. Overall results show that our proposal for collaboration leads to 12% and 15% decrease in route distance and time, respectively. Average asset utilization is seen to increase by about 5% as well.

As the circuit size increases in modern electronics, the design process becomes more complicated. Even though the hardware design process is divided into multiple phases, many of the divided problems are still extremely time consuming to solve. One of these NP-hard problems is the routing problem. As electronics step into the deep submicron era, optimizing the routing becomes increasingly important. One of the methods to solve global routing is to formulate the problem as an integer programming (IP) problem. This formulation can then be relaxed into a linear programming problem and solved using interior point method. This thesis investigates two new approaches to optimize the speed of solving global routing using Karmarkar’s interior point method, as well as the effect of combining various optimizations with these new approaches. The first proposed approach is to utilize solution stability as the interior point loop converges, and attempt to remove solutions that have already stabilized. This approach reduces the problem size and allows subsequent interior point iterations to proceed faster. The second proposed approach is to solve the inner linear system (projection step) in interior point method in parallel. Experimental results show that for large routing problems, the performance of the solver is improved by the optimization approaches. The problem reduction stage allows for great speedup in the interior point iterations, without affecting the quality of the solution significantly. Furthermore, the timing required to solve inner linear system in the interior point method is improved by solving the problem in parallel. With these optimizations, solving the routing problem using the IP formation becomes increasingly more efficient. By solving an efficient parallel IP formation rather than a traditional sequential approach, more efficient optimal solutions which incorporate multiple conflicting objectives can be achieved.

In this paper, we propose a trust-based message propagation and evaluation framework to support the effective evaluation of information sent by peers and the immediate control of false information in a VANET. More specifically, our trust-based message propagation collects peers’ trust opinions about a message sent by a peer (message sender) during the propagation of the message. We improve on an existing cluster-based data routing mechanism by employing a secure and efficient identity-based aggregation scheme for the aggregation and propagation of the sender’s message and the trust opinions. These trust opinions weighted by the trustworthiness of the peers modeled using a combination of role-based and experience-based trust metrics are used by cluster leaders to compute a ma jority opinion about the sender’s message, in order to proactively detect false information. Malicious messages are dropped and controlled to a local minimum without further affecting other peers. Our trust-based message evaluation allows each peer to evaluate the trustworthiness of the message by also taking into account other peers’ trust opinions about the message and the peer-to-peer trust of these peers. The result of the evaluation derives an effective action decision for the peer. We evaluate our framework in simulations of real life traffic scenarios by employing real maps with vehicle entities following traffic rules and road limits. Some entities involved in the simulations are possibly malicious and may send false information to mislead others or spread spam messages to jam the network. Experimental results demonstrate that our framework significantly improves network scalability by reducing the utilization of wireless bandwidth caused by a large number of malicious messages. Our system is also demonstrated to be effective in mitigating against malicious messages and protecting peers from being affected. Thus, our framework is particularly valuable in the deployment of VANETs by achieving a high level of scalability and effectiveness.

This thesis presents a protocol for intervehicle communication for use in Vehicular Ad Hoc Networks (VANET). VANET is a natural extension of mobile ad hoc networks (MANET) in which the restrictions related to power and mobility are relaxed. The routing protocols used for MANETs are generally dependent on the state of the network. With changes in the network topology, routing messages are generated so that the states of the routers in the network are updated. In the case of VANETs, in which the level of node mobility is high, message-routing overhead has serious implications for the scalability and throughput of the routing protocol. This thesis introduces criteria that are recommended for use when protocols are designed for VANET applications and presents the Selected Node Geographic Forwarding (SNGF) protocol. The SNGF protocol implements controlled flooding in an efficient manner in order to reduce unnecessary communication overhead. The protocol has a destination discovery mechanism that allows it to initiate correspondence between nodes without reliance on static location services. The protocol avoids formation of clusters by using the concept of selective forwarding, thus providing the advantages of cluster based approaches without actually forming one itself. It effectively deals with blind flooding by introducing a comprehensive retransmission time delay in the nodes. This retransmission delay favors the nodes in the direction of the destination and prevents other nodes from retransmitting the same message. The SNGF protocol does not use routing tables, which require frequent updates in mobile networks, instead it relies on directing the messages to geographic locations which are forwarded by any available intermediary nodes. The protocol also provides techniques for handling network fragmentation which can be a frequent problem in vehicular networks. It is capable of delayed message transmission and multiple route discovery in the case of the non-availability of the shortest path to the destination. To evaluate the performance of the SNGF protocol, an extensive study of mobile networks was conducted using the NS2 simulator. The simulation results demonstrate the reachability of the protocol, its scalability advantages and its total independence from location services. The SNGF protocol allows each participating node to operate independently of other nodes in the network. Nodes in the network are able to communicate with other nodes without ever becoming dependent on intermediary nodes. This feature opens new possibility for individual node based application development in ad hoc networks. The traffic profiling is described as it would be observed by an independent node participating in VANET using the SNGF protocol. The node communicates with other nodes and collects relevant data through the discourse capability of SNGF. The data collected by the node is viewed as a snapshot in time of the traffic conditions down the road based upon which future traffic condition is predicted. Traffic profiling is investigated for different levels of VANET deployment. The simulation results show that the proposed method of traffic profiling in a VANET environment using the SNGF protocol is viable for even lower levels of deployment.

Delay-tolerant networking (DTN) has recently received considerable attention from the research community. This type of networks is characterized by frequent disconnections due to propagation phenomena, node mobility, and power outages. Thus, the complete path between the source and the destination may never have existed. This context requires the design of new communication paradigms and techniques that will make communication possible in these environments. To achieve message delivery, researchers have proposed the use of store-carry-and-forward protocols, whereby a node may store the message and carry it until an appropriate forwarding opportunity arises. Many flooding-routing schemes have been proposed for DTNs in order to increase the probability of message delivery. However, these schemes suffer from excessive energy consumption, severe contention that significantly degrades their performance, especially if we account for the fact that each node could be a hand-held and battery-powered device with stringent buffer size limitation. With such buffer limitations at the DTN nodes, message drop/loss could happen due to buffer overflow. In order to address the problem and improve the performance of DTNs, this thesis focuses on two main design objectives; first, the design and evaluation of new multi-copy routing schemes; second, the design and evaluation of new scheduling and dropping policies to reduce message drop/loss due to buffer overflow. To fulfill the first objective, a protocol called Self Adaptive Routing Protocol (SARP) is introduced. It is a multi-copy scheme designed to suit resource-sufficient DTNs. Based on SARP, two multi-copy routing schemes are further developed to suit resource-limited DTNs, in which compensating the traffic demand become a challenge: i) the Self Adaptive Utility-based Routing Protocol (SAURP), ii) and the Adaptive Reinforcement based Routing Protocol (ARBRP). The introduced protocols form a new framework of DTNs aiming to significantly reduce the resource requirements of flooding-based routing schemes. Each introduced scheme has its own way of exploring the possibility of taking mobile nodes as message carriers in order to increase the delivery ratio of the messages. In SAURP, the best carrier for a message characterized by jointly considering the inter-contact time that is obtained using a novel contact model and the network status, such as including wireless link condition and nodal buffer availability. In ARBRP, the routing problem is solved by manipulating a collaborative reinforcement learning technique, where a group of nodes can cooperate with each other to make a forwarding decision for the stored messages based on a cost function at each contact with another node. ARBRP is characterized by not only considering the contact time statistics, but also looks into the feedback on user behavior and network conditions, such as congestion and buffer occupancy sampled during each previous contact with any other node. The thesis argues and proves that the nodal movement and the predicted collocation with the message recipient can serve as meaningful information to achieve an intelligent message forwarding decision at each node. Therefore, the introduced protocols can achieve high efficiency via an adaptive and intelligent routing mechanism according to network conditions. To fulfill the second objective, we further enhanced the performance of DTN routing by introducing message scheduling and dropping policies such that the delivery ratio is increased and/or the delivery delay is reduced. This thesis investigates new buffer management and scheduling policies to improve the performance of flooding and utility-based forwarding routing in DTNs, such that the forwarding/dropping decision can be made at a node during each contact for either optimal message delivery ratio or message delivery delay. To examine their effectiveness, the introduced protocols and the buffer management and scheduling policies have been implemented and compared to a number of existing counterpart approaches. A near-realistic mobility model is used for testing. A number of scenarios are used to evaluate the performance of the introduced techniques in terms of delivery delay, ratio, and the number of transmissions performed.

This thesis proposes a potential solution for future ubiquitous broadband wireless access networks, called a cellular wireless mesh network (CMESH), and investigates a number of its performance issues. A CMESH is organized in multi-radio, multi-channel, multi-rate and multi-hop radio cells. It can operate on abundant high radio frequencies, such as 5-50 GHz, and thus may satisfy the bandwidth requirements of future ubiquitous wireless applications.<p> Each CMESH cell has a single Internet-connected gateway and serves up to hundreds of mesh nodes within its coverage area. This thesis studies performance issues in a CMESH, focusing on cell capacity, expressed in terms of the max-min throughput. In addition to introducing the concept of a CMESH, this thesis makes the following contributions.<p> The first contribution is a new method for analyzing theoretical cell capacity. This new method is based on a new concept called Channel Transport Capacity (CTC), and derives new analytic expressions for capacity bounds for carrier-sense-based CMESH cells.<p> The second contribution is a new algorithm called the Maximum Channel Collision Time (MCCT) algorithm and an expression for the nominal capacity of CMESH cells. This thesis proves that the nominal cell capacity is achievable and is the exact cell capacity for small cells within the abstract models.<p> Finally, based on the MCCT algorithm, this thesis proposes a series of greedy algorithms for channel assignment and routing in CMESH cells. Simulation results show that these greedy algorithms can significantly improve the capacity of CMESH cells, compared with algorithms proposed by other researchers.

We analyze the problem of distributing units of a product, by a capacitated vehicle, from one storage location (depot) to multiple retailers. The demand processes at the retailers are stochastic and time-dependent. Based on current inventory information, the decision maker decides how many units of the product to deposit at the current retailer, or pick up at the depot, and which location to visit next. We refer to this problem as the stochastic vendor managed inventory (SVMI) problem. In the Markov decision process model of the SVMI problem, we show how a retailer continues to be the vehicle's optimal destination as inventory levels of the retailers vary. Furthermore, an optimal inventory action is shown to have monotone relations with the inventory levels. The multi-period SVMI problem and the infinite horizon (periodic) SVMI problem are analyzed. Additionally, we develop three suboptimal solution procedures, complete a numerical study, and present a case study, which involves a distribution problem at the Coca-Cola Enterprises, Inc. We consider four variations of the SVMI problem, which differ in the available state information and/or the vehicle routing procedure. Analytically, we compare the optimal expected total rewards for the SVMI problem and its variations. Our computational experience suggests a complementary relationship between the quality of state information and the size of the set of retailers that the vehicle can visit.