The enhanced Polar Outflow Probe (ePOP) satellite is to be launched in 2007. One of the 8 instruments it will carry is a Radio Receiver Instrument (RRI) which is a passive radio receiver. The RRI will detect HF (High Frequency band 3 to 30 MHz) radio waves from ground transmitters, one of which is the Saskatoon SuperDARN radar. The modification of an HF radar wave as it propagates through the ionosphere to the satellite is the dominant scientific interest of this thesis. The modification of a radar wave as it propagates through the ionosphere can be used to characterize the ionosphere and reveal a better understanding of magnetoionic radar wave propagation. A ray tracing program has been written to determine characteristics of the wave, including the wave path and the full polarization state, at the satellite receiver. </p> As a confirmation of the ray tracing program abilities, data from a similar transionospheric experiment in 1978, the ISIS II satellite mission, has been analyzed and compared with simulated results. The ISIS II transionospheric experiment received radar signals from a transmitter (9.303 MHz) located in Ottawa, Canada. These signals were analyzed and it was noted that the signal periodically faded in and out both due to differential Faraday rotation effects (due to propagation through an ionized medium and reception on a single dipole antenna) and due to satellite spin rotation at rates up to 13 Hz. Also observed was a splitting of the received signal into Ordinary (O-mode) and Extraordinary (X-mode) components causing a delay between the arrival of the modes at ISIS II of up to 0.8 ms. Simulations have been carried out to model the radar wave propagation from the ground transmitter through the ionized medium of the ionosphere to the spacecraft. The modelled signal shows very similar trends to the observed signal. A linear regression analysis comparing observed to simulated fade rates gave values of slope equal to 1.07 and regression coefficient equal to 0.934. The regression analysis of mode delay gave values of slope equal to 1.14 and regression coefficient equal to 0.930. </p>Ray path modelling has also been simulated for the RRI experiment on ePOP. These simulations have been carried out for various ionospheric and satellite pass configurations. The expected fade rates, mode delays, and latitudinal range of received signal was determined from the simulated data in each case. The dependence of these characteristics on the various pass configurations are presented and discussed.

Satellite radio has attained great popularity because of its wide range of geographical coverage and high signal quality as compared to the terrestrial broadcasts. Most Satellite Digital Radio (SDR) based systems favor multi-carrier transmission schemes, especially, orthogonal frequency division multiplexing (OFDM) transmission because of high data transfer rate and spectral efficiency. It is a challenging task to find a suitable platform that supports fast data rates and superior processing capabilities required for the development and deployment of the new SDR standards. Field programmable gate array (FPGA) devices have the potential to become suitable development platform for such standards. Another challenging factor in SDR systems is the distortion of variable envelope signals used in OFDM transmission by the nonlinear RF power amplifiers (PA) used in the base station transmitters. An attractive option is to use a linearizer that would compensate for the nonlinear effects of the PA. In this research, an OFDM transmitter, according to European Telecommunications Standard Institute (ETSI) SDR Technical Specifications 2007-2008, was designed and implemented on a low-cost Xilinx FPGA platform. A weakly nonlinear PA, operating in the L-band SDR frequency (1.450-1.490GHz), was used for signal transmission. An FPGA-based, low-cost, adaptive linearizer was designed and implemented based on the digital predistortion (DPD) reference design from Xilinx, to correct the distortion effects of the PA on the transmitted signal.

The common neurotrophin receptor, p75NTR, has been implicated in diverse responses of sensory neurons including a role in nociception following nerve injury, suggesting that it may serve a similar role in intact sensory neurons and their satellite glial cells (SGCs). To examine the impact of suppressing neuronal p75NTR expression on known molecular modulators/regulators of the nociceptive state namely, the sodium channels NaV1.8 and NaV1.9, the nerve growth factor receptor TrkA, the potassium channel Kir4.1, glial fibrillary acidic protein (GFAP), SGC p75NTR, connexin 43, we intrathecally infused p75NTR anti-sense oligonucleotides (AS OGN), previously shown by Obata et al. (2006) to effectively suppress p75NTR expression in intact neurons. Male, Wistar rats were divided into three groups, receiving either no treatment (non-infused), seven day intrathecal infusion of p75NTR AS OGN or sense control (SC OGN) via an osmotic pump. Serial L4 and L5 DRG sections were processed for immunohistochemistry to detect alterations in NaV1.8, NaV1.9, TrkA, Kir4.1, p75NTR, GFAP and connexin-43 protein expression. Sciatic nerve sections were also processed for immunohistochemistry to detect NaV1.8, NaV1.9, TrkA and GFAP protein expression. Infusion of p75NTR AS OGNs resulted in a significant decrease in neuronal p75NTR expression, however no significant change was observed in neuronal NaV1.8, NaV1.9 or TrkA expression relative to SC OGN treated or non-infused controls. On the contrary, SGC expression of phenotypic markers normally associated with the reactive state that is induced in these cells in response to peripheral nerve axotomy was dramatically altered. More specifically, in response to p75NTR AS OGN infusion, there was a significant increase in SGC protein expression of the cytoskeletal protein GFAP and p75NTR, along with a significant decrease in expression of the inward rectifying potassium channel Kir4.1. Preliminary data also revealed this induced reactive state in SGCs to be associated with an increase in the number of SGCs surrounding individual neurons as well as increased SGC expression of the gap junction protein, connexin 43. In conclusion, reductions in neuronal p75NTR expression and potentially reduced neurotrophin signaling lead to alterations in neuron/glial or axon/glial communication that results in induction of a reactive phenotype in the associated SGCs. With our ever increasing understanding of the role of SGCs modulating pain states, elucidation of the pathways leading to adoption of pathological phenotypes can help in the identification of novel therapeutic targets.

The enhanced Polar Outflow Probe (ePOP) satellite is to be launched in 2007. One of the 8 instruments it will carry is a Radio Receiver Instrument (RRI) which is a passive radio receiver. The RRI will detect HF (High Frequency band 3 to 30 MHz) radio waves from ground transmitters, one of which is the Saskatoon SuperDARN radar. The modification of an HF radar wave as it propagates through the ionosphere to the satellite is the dominant scientific interest of this thesis. The modification of a radar wave as it propagates through the ionosphere can be used to characterize the ionosphere and reveal a better understanding of magnetoionic radar wave propagation. A ray tracing program has been written to determine characteristics of the wave, including the wave path and the full polarization state, at the satellite receiver. </p> As a confirmation of the ray tracing program abilities, data from a similar transionospheric experiment in 1978, the ISIS II satellite mission, has been analyzed and compared with simulated results. The ISIS II transionospheric experiment received radar signals from a transmitter (9.303 MHz) located in Ottawa, Canada. These signals were analyzed and it was noted that the signal periodically faded in and out both due to differential Faraday rotation effects (due to propagation through an ionized medium and reception on a single dipole antenna) and due to satellite spin rotation at rates up to 13 Hz. Also observed was a splitting of the received signal into Ordinary (O-mode) and Extraordinary (X-mode) components causing a delay between the arrival of the modes at ISIS II of up to 0.8 ms. Simulations have been carried out to model the radar wave propagation from the ground transmitter through the ionized medium of the ionosphere to the spacecraft. The modelled signal shows very similar trends to the observed signal. A linear regression analysis comparing observed to simulated fade rates gave values of slope equal to 1.07 and regression coefficient equal to 0.934. The regression analysis of mode delay gave values of slope equal to 1.14 and regression coefficient equal to 0.930. </p>Ray path modelling has also been simulated for the RRI experiment on ePOP. These simulations have been carried out for various ionospheric and satellite pass configurations. The expected fade rates, mode delays, and latitudinal range of received signal was determined from the simulated data in each case. The dependence of these characteristics on the various pass configurations are presented and discussed.

Satellite radio has attained great popularity because of its wide range of geographical coverage and high signal quality as compared to the terrestrial broadcasts. Most Satellite Digital Radio (SDR) based systems favor multi-carrier transmission schemes, especially, orthogonal frequency division multiplexing (OFDM) transmission because of high data transfer rate and spectral efficiency. It is a challenging task to find a suitable platform that supports fast data rates and superior processing capabilities required for the development and deployment of the new SDR standards. Field programmable gate array (FPGA) devices have the potential to become suitable development platform for such standards. Another challenging factor in SDR systems is the distortion of variable envelope signals used in OFDM transmission by the nonlinear RF power amplifiers (PA) used in the base station transmitters. An attractive option is to use a linearizer that would compensate for the nonlinear effects of the PA. In this research, an OFDM transmitter, according to European Telecommunications Standard Institute (ETSI) SDR Technical Specifications 2007-2008, was designed and implemented on a low-cost Xilinx FPGA platform. A weakly nonlinear PA, operating in the L-band SDR frequency (1.450-1.490GHz), was used for signal transmission. An FPGA-based, low-cost, adaptive linearizer was designed and implemented based on the digital predistortion (DPD) reference design from Xilinx, to correct the distortion effects of the PA on the transmitted signal.

The proliferation of nuclear weapons is a great threat to world peace and stability. The question of strengthening the nonproliferation regime has been open for a long period of time. In 1997 the International Atomic Energy Agency (IAEA) Board of Governors (BOG) adopted the Additional Safeguards Protocol. The purpose of the protocol is to enhance the IAEA’s ability to detect undeclared production of fissile materials in member states. However, the IAEA does not always have sufficient human and financial resources to accomplish this task. Developed here is a concept for making use of human and technical resources available in academia that could be used to enhance the IAEA’s mission. The objective of this research was to study the feasibility of an academic community using commercially or publicly available sources of information and products for the purpose of detecting covert facilities and activities intended for the unlawful acquisition of fissile materials or production of nuclear weapons. In this study, the availability and use of commercial satellite imagery systems, commercial computer codes for satellite imagery analysis, Comprehensive Test Ban Treaty (CTBT)verification International Monitoring System (IMS), publicly available information sources such as watchdog groups and press reports, and Customs Services information were explored. A system for integrating these data sources to form conclusions was also developed. The results proved that publicly and commercially available sources of information and data analysis can be a powerful tool in tracking violations in the international nuclear nonproliferation regime and a framework for implementing these tools in academic community was developed. As a result of this study a formation of an International Nonproliferation Monitoring Academic Community (INMAC) is proposed. This would be an independent organization consisting of academics (faculty, staff and students) from both nuclear weapon states (NWS) and non-nuclear weapon states (NNWS). This community analyzes all types of unclassified publicly and commercially available information to aid in detection of violations of the non-proliferation regime. INMAC shares all of this information with the IAEA and the public. Since INMAC is composed solely by members of the academic community, this organization would not demonstrate any biases in its investigations or reporting.

In this thesis, the positioning accuracy of the techniques in Taiwan¡¦s environment can be estimated by using the existing positioning algorithms. The satellite interferer location techniques for geostationary satellites can produce an error ellipse by measuring time difference of arrival (TDOA) and frequency difference of arrival (FDOA) between two signals which pass through the different uplink and downlink path of two satellites. In order to reduce the positioning error of the TDOA/FDOA technique, we proposed a method that using a helicopter to achieve the multibeam antenna (MBA) positioning. Using angle measurement, the positioning is carried out by fitting the measured power ratio of the interference signals received by the multibeam antenna to the gain ratio of the beams as a function of the incoming angle. This hybrid positioning technique was shown to reduce the positioning error and search area of the error ellipse.

Space vehicle is a kind of tool and weapon for transporting materials and personnel, conveying energy and execution work in space. The war of 21st century is a Hi-Tech war to fight for the power over space control and information transmission. Space power means the control of information transmission, and therefore the victory of this war and quality of space vehicle is the key factor in determining Whether one has the power space in. China was developed space vehicle technology since 1956 After great efforts for half a century, it has already established certain foundation. China like U.S.A and Russia, has invested huge funds and manpower in developing space science and technology. China hopes to improve military strength, drive the development of relevant industries and economy, and increase national competitiveness and overall strength through the development in space vehicle science and technology, and further conquer this expects to new high land of space. This paper aims at studying the development, capabilities, restrictions, and breakthroughs the space vehicle technology of China in terms of China¡¦s position on the control over space and its strategic intention in developing space vehicles. This paper reveals the direction of space vehicle development in China and suggests measures for maintaining Taiwan security. It will help to provide a relevant background for the future study of space vehicle development in China.

Thesis (Ph. D.)--University of Texas at Austin, 2000. / Vita. Includes bibliographical references (leaves 334-349). Available also in a digital version from Dissertation Abstracts.

Skeletal muscle regeneration involves a tightly regulated coordination of cellular and signaling events to remodel and repair the site of injury. When this coordination is perturbed, the regenerative process is impaired. The expression of insulin-like growth factor-I (IGF-I) is robust in the typical muscle regenerative program, promoting cell survival and increasing myoblast activity. In this project, we found that severely depressed IGF-I expression and intracellular signaling in aged skeletal muscle coincided with impaired regeneration from ischemia/reperfusion (I/R). To hasten muscle regeneration, we developed the PEGylated fibrin gel (PEG-Fib) system as a means to intramuscularly deliver IGF-I in a controlled manner to injured muscle. This strategy resulted in greatly improved muscle function and histological assessment following 14 days of reperfusion, which are likely mediated by improved myofiber survival. Recent evidence suggests macrophages (MPs) are responsible for the upregulation of IGF-I following injury, therefore we developed a rapid, reproducible, and cost-effective model of investigating MP profiles in injured muscle via flow cytometry. Using information gathered from this model, we found that increasing the number of a non-inflammatory MP population improves the recovery of muscle from I/R. These data demonstrate that immunomodulatory therapies have the potential to greatly improve the recovery of skeletal muscle from injury. / text