Detta arbete, som utgår ifrån observationen att många spel inom survival horror-genren använder sig av en realistisk grafisk stil på sina texturer, undersöker om det är möjligt att förmedla samma läskiga känsla genom användandet av en stiliserad, eller tecknad, grafisk stil. Tre 3D-modeller föreställande monster, modellerade med inspiration från survival horror-spel, texturerades på ett sätt som motsvarade en realistisk grafisk stil, samt ett som motsvarade en stiliserad grafisk stil. Dessa låg sedan som grund för en enkätundersökning där respondenterna fick välja vilken version av monstren som var läskigast.

Objetivos. Determinar la influencia de los marcadores: antígeno Ki67 y del gen p53 como factores pronóstico independiente en la sobrevida de los pacientes con Glioblastoma Multiforme. Materiales y métodos. Se revisó un total de 150 casos de pacientes con diagnóstico preliminar de Glioblastoma Multiforme (GBM) atendidos en el Instituto Nacional de Enfermedades Neoplásicas, entre los años 2008 y 2013 y se seleccionaron 60 casos que cumplían con los criterios de inclusión requeridos, información clínico patológica y seguimiento adecuado. Resultados. La media de edad es de 51 años (8-73 años), conformado por 34 hombres (56.7%) y 26 mujeres (43.3%). La mediana de sobrevida global (SG) es menor en el grupo de pacientes que sobreexpresaron el antígeno Ki67 (>= 20%), frente a los pacientes que tuvieron niveles de expresión moderada del antígeno (>= 10%). (26.5 vs 40 meses). Asimismo, se evidencia que la SG es mayor en los pacientes que expresan positivamente el gen p53 (>20%), frente a los pacientes que no llegaron a expresarlo. (40 vs 30 meses). Conclusiones. Tanto la expresión del antígeno ki67 como la expresión del gen p53 se pueden determinar como factores pronóstico de la sobrevida de pacientes que hayan sido diagnosticados con GBM con el fin de mejorar la calidad de vida de estos pacientes dándoles la posibilidad de recibir un tratamiento más específico acorde a los valores de estos marcadores inmunohistoquímicos.Objectives.To evaluate the influence of markers: Ki67 antigen and p53 gene as independent prognostic factors in the survival of patients with Glioblastom Multiform. Materials and methods. A total of 150 cases of patients with a preliminary diagnosis of Glioblastom Multiform (GBM) treated at the National Institute of Neoplastic Diseases between 2008 and 2013 were reviewed and 60 cases were selected that satisfy the inclusion criteria required, clinical pathological information and adequate follow-up information. Results. The mean age is 51 years (8-73 years), made up of 34 men (56.7%) and 26 women (43.3%). The median overall survival (OS) was lower in the group of patients who overexpressed the Ki67 antigen (> = 20%), compared to the patients who had moderate levels of antigen expression (> = 10%). (26.5 vs. 40 months). As well evidenced that the OS is higher in patients who positively express the p53 gene (> 20%), compared to patients who did not express it. (40 vs. 30 months. Conclusion. Both, the expression of the ki67 antigen and the expression of the p53 gene could be determined as prognostic factors for the survival of patients who have been diagnosed with GBM in order to improve the quality of life of these patients giving them the possibility of receiving a more specific treatment according to the values of these immunohistochemically markers.

No description available.

Gays and lesbians have long struggled for their rights as citizens, yet only recently has their struggle been truly politicized in a way that fosters mobilization. When and why social movements coalesce despite the many obstacles to collective action are fundamental questions in comparative politics. While examining social movements is worthwhile, it is important to examine not only when and why a social movement forms, but also when and why a social movement is successful. This dissertation tackles the latter of these objectives, focusing on when and why social movements have success in terms of their duration from the time of their formation until their desired policy output is produced.

I explore nature in order to understand something that is becoming increasingly unfamiliar. I wonder about accelerated human transactions with nature: the control of animals, land, and resources for pleasure, consumption or survival; and how these actions manifest themselves visually in the modern world. Through images, I create new ideas about my surroundings. My questions about nature are documented through my work employing subtlety to narrate stories of contemporary environments.

Magister Public Health - MPH / Background: Malnutrition is a complex condition profoundly impacting child mortality and morbidity, especially in sub-Saharan Africa. Severe acute malnutrition is of growing concern locally where unacceptable mortality rates persist, despite reasonable standards of clinical care. Aim: To determine factors associated with morbidity and mortality in children under-five years admitted with severe acute malnutrition to a regional paediatric hospital in KwaZulu-Natal. Methodology: This was a quantitative study. A retrospective observational study design was used. Medical records of all children with severe acute malnutrition, under the age of five years, admitted between April 2015 and December 2016 to the regional paediatric hospital in KwaZulu-Natal were included. Data was obtained from medical records and admission books. A trained research assistant was used to extract and record data with a piloted data extraction tool. Data was entered and cleaned using Microsoft Excel and analysed using SPSS (v 20) and STATA (v 14). Descriptive summary statistics were used to describe the characteristics of the study population and bivariate analysis using t-tests and Chi-square tests to determine significance. Kaplan Meier and Multivariate Cox regression was used to assess the association of variables with morbidity and mortality. Results: Of the 276 eligible case records included in the study, 54% were male and 90% of all cases were younger than 2 years. Even though associations did not reach significance, teenage pregnancy and unemployment was high amongst the caregivers of the study population. Most of the malnourished children admitted (74%) presented with multiple comorbidities. Diarrhoea (43%), HIV- infection (30%) and respiratory tract infections (30%) were the top three comorbidities found, followed by tuberculosis (27%). The overall mortality rate was 8.7%. Survival probability was significantly reduced in children with pneumonia and those who presented with hypoglycaemia, dehydration, dermatosis, severe pallor, altered consciousness or shock on admission (p < 0.05). There was a significantly increased risk of death in males (HR = 0.174, 95%CI = 0.05 - 0.665), and in those who presented with dehydration (HR = 4.1, 95%CI = 1.25 - 13.59), evidence of lethargy or coma (HR = 4.2, 95%CI = 1.04 - 17.12) or multiple clinical signs (HR = 4.4, 95% CI =2.56 - 7.59) on admission (p < 0.05). The comorbidities HIV-infection (HR = 9.9, 95%CI = 1.39 - 70.68) and pneumonia (HR = 3.4, 95%CI = 1.56 - 7.43) showed a significantly increased mortality risk (p < 0.05). Conclusion: This study supports the body of evidence that despite reasonable standards of hospital care, it is difficult to obtain the target for severe acute malnutrition mortality (< 5%), likely due to the presence of contextually specific factors. Local interventions at hospital, primary health care and community level is needed, as well as further research to facilitate comprehensive policy-making.

Globally, child mortality is a great concern, especially in resource-limited settings. The Millennium Development Goal (MDG) 4 was set with an aim to reduce under-5 child mortality by two-thirds between 1990 and 2015. This study examines mortality trends in infants, 1-4 and above 5-year-old children in rural KwaZulu-Natal, South Africa, the causes of death as well as the association of maternal HIV status and Antiretroviral Treatment (ART) usage to child mortality. We use a longitudinal birth cohort study design of children born between 1st January 2004 and 31st December 2010, in the Africa Centre Demographic Surveillance Area (DSA) in rural KwaZulu-Natal, South Africa. Children had to have been resident in the DSA at the time of birth. A total of 12,413 children born in the study period were eligible for this study. The main outcome measure was mortality either in infancy, the 1-4 year period or at 5 and above years of age, while assessing its association with maternal HIV and Antiretroviral Treatment uptake (ART) status on a time-varying basis. A total of 619 children died during the study period and mortality was observed to be highest in the infant group with 67% of the children dying in infancy. Fifteen percent of mothers were HIV positive at the time of birth of the child, about 59% were HIV negative while the HIV status of the rest was unknown. There was a three-fold increase in mortality observed for both infants and 1-4 year olds, who had mothers who were HIV infected compared to children whose mothers were HIV negative (p<0.05). Children whose mothers were on Antiretroviral Treatment (ART) however had a reduced mortality compared to those whose mothers were not on treatment. Infants and 1-4year olds whose mothers HIV status was not reported had a two-fold increase in mortality. Low maternal education, single motherhood, multiple births and parity of four or more children were also associated with increased child mortality. We concluded that although mortality varied by the age of the child, children born to mothers who were HIV positive had higher mortality rates than children born to HIV negative mothers but being on Anti Retroviral Treatment (ART) reduced children mortality. Interventions targeting HIV positive pregnant women and mothers should be carried out in the study area, with specific emphasis on reducing child mortality associated with maternal HIV status.

Thesis advisor: Bonnie Jefferson / “Any one of the prisoners would have been willing to die for his country” (Chesley 68). This quote summarizes the unbreakable will of heroic American Prisoners of War (POWs). This paper explores the personal narratives of four POWs who were held captive during World War II and four who were held during the Vietnam War and seeks to determine how their discourse affects American ideologies of war. By examining these narratives through narrative criticism and Kenneth Burke’s Rhetoric of Rebirth, this analysis shows how POWs reveal the sociopolitical environments of the countries in which they are held by structuring their experiences under a common framework. While the four narratives concerning World War II shed light on the differences in captivity between different countries in the Axis Powers, the narratives from the Vietnam War rationalize American involvement in the conflict. Even though the Vietnam War was one of the most misunderstood and unpopular events in American history, this paper shows how personal POW accounts can justify and garner support for American intervention into foreign affairs. These survival narratives reveal a depth of human strength in the face of horrible circumstances that becomes an inspiration for audiences of this discourse. / Thesis (BA) — Boston College, 2010. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: College Honors Program. / Discipline: Communication.

The thesis examines different international figures of dissident female protectors, who resist, challenge, disrupt and/or reinforce the multiple ‘logics of protection' of/in International Security. Locating the existing approaches to, and explorations of, the notion of ‘logic of masculinist protection' in feminist security studies, the thesis seeks to expand and pluralise this work by arguing that logics of protection are, in fact, plural and intersecting. It investigates how such logics rely on multiple power relations of not only gender, but also race, sexuality, (settler) coloniality, and so forth. From this point of departure, the thesis identifies and examines different practices and sites of resistance to such plural and intersecting logics. It focuses on the acts of iconic female protectors operating within and beyond official institutions of protection. Mobilising Foucault's work on parrhesia, understood as a practice that involves speaking fearless truth to power, the thesis thus analyses the ways in which different female protectors become parrhesiastes, in their acts of ‘snapping' in reaction to logics of protection, by speaking risky truths to their constitutive power. The thesis examines the cases of Malalai Joya, Chelsea Manning, the Gulabi Gang, and Idle No More as parrhesiastic ‘snaps' that problematise, disrupt, and/or reinforce logics of protection of/in International Security. Finally, the thesis concludes by reflecting on what such analysis means for our understanding of parrhesia as a political and ethical practice today in the context of international security, delineating its implications for feminist security studies and IR more generally.

This study was undertaken in an attempt to determine some of the factors which may influence the survival of Utah game farm-reared pheasants following their release into the wild. The survival of these birds is below the desired level after they are released, as is indicated by the low percentage taken by the sportsmen during the hunting season. In recent years the return from released game farm-reared pheasants is about 7 to 8 percent. Consequently, if survival rate of these birds could be increased, more birds would be available to supplement the wild stock. Also, an increase in the pheasant population throughout the state would make more birds available to sportsmen during the hunting season.