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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Automatic mass segmentation in mammographic images

Oliver i Malagelada, Arnau 11 July 2007 (has links)
Aquesta tesi està emmarcada dins la detecció precoç de masses, un dels símptomes més clars del càncer de mama, en imatges mamogràfiques. Primerament, s'ha fet un anàlisi extensiu dels diferents mètodes de la literatura, concloent que aquests mètodes són dependents de diferent paràmetres: el tamany i la forma de la massa i la densitat de la mama. Així, l'objectiu de la tesi és analitzar, dissenyar i implementar un mètode de detecció robust i independent d'aquests tres paràmetres. Per a tal fi, s'ha construït un patró deformable de la massa a partir de l'anàlisi de masses reals i, a continuació, aquest model és buscat en les imatges seguint un esquema probabilístic, obtenint una sèrie de regions sospitoses. Fent servir l'anàlisi 2DPCA, s'ha construït un algorisme capaç de discernir aquestes regions són realment una massa o no. La densitat de la mama és un paràmetre que s'introdueix de forma natural dins l'algorisme. / This thesis deals with the detection of masses in mammographic images. As a first step, Regions of Interests (ROIs) are detected in the image using templates containing a probabilistic contour shape obtained from training over an annotated set of masses. Firstly, PCA is performed over the training set, and subsequently the template is formed as an average of the gradient of eigenmasses weighted by the top eigenvalues. The template can be deformed according to each eigenmass coefficient. The matching is formulated in a Bayesian framework, where the prior penalizes the deformation, and the likelihood requires template boundaries to agree with image edges. In the second stage, the detected ROIs are classified into being false positives or true positives using 2DPCA, where the new training set now contains ROIs with masses and ROIs with normal tissue. Mass density is incorporated into the whole process by initially classifying the two training sets according to breast density. Methods for breast density estimation are also analyzed and proposed. The results are obtained using different databases and both FROC and ROC analysis demonstrate a better performance of the approach relative to competing methods.

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