Made available in DSpace on 2014-06-11T19:28:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-05-14Bitstream added on 2014-06-13T20:36:46Z : No. of bitstreams: 1 zanetti_mc_me_rcla.pdf: 772213 bytes, checksum: 7896b5d7cf2e3d207bcbbc502ba1f503 (MD5) / Atualmente, nossa sociedade vem sofrendo uma transformação sem precedentes, no qual, a população, de uma maneira geral, tem se deparado com inúmeros distúrbios, sejam eles, de ordem: social, psicológica e biológica. Esses distúrbios têm refletido em uma menor qualidade de vida e saúde de nossa população, bem como, aumento nos níveis de estresse, diminuição na qualidade de sono, entre outros. Por outro lado, o exercício físico, e a Educação Física escolar vem sendo apontados como importantes agentes promotores de saúde. Pensando nisso, procuramos investigar a influência destas atividades, sobre a estrutura do sono de 58 alunas do sexo feminino, com idades entre 11 e 12 anos (l11.47), da cidade de Limeira SP. Para a coleta dos dados foram aplicados três questionários, no qual, o questionário 1, foi composto por perguntas relativas: à estrutura de sono; problemas de saúde; uso de medicamentos; relacionamento familiar e com amigos; hábitos pessoais; entre outros; o questionário 2 (PAQ-C), foi utilizado para medir o nível de atividade física regular e classificar as adolescentes em ativas e sedentárias; o questionário 3, foi estruturado e utilizado para verificar a percepção subjetiva de qualidade de sono. Posteriormente, aplicamos o teste Qui-quadrado para verificar se havia diferença entre as respostas apresentadas pelas alunas ativas e sedentárias para as questões referentes ao questionário 1, e a questão relativa à percepção subjetiva de qualidade de sono (questionário 3). Adicionalmente, empregamos a análise residual nas questões, onde foi encontrada diferença significativa. Este teste foi utilizado para verificar o comportamento das variáveis e categorias, bem como, determinar as variáveis que mais contribuíram para a diferença encontrada. O teste t para amostras independentes foi aplicado para verificar se havia diferença... / Currently, our society has been suffering a transformation without precedents, in which, the population, in a general way, if has come across with innumerable disorders, is they, social, psychological and biological order. These disorders have reflected in a lesser life quality and health of our population, increase in the levels of stress, reduction in the sleep quality, among others. On the other hand, the physical exercise, and the Physical Education in school have been pointed as important promotional agents of health. Thinking about this, we decided to investigate the influence of these activities, on the structure of the sleep of 58 girls, with ages between 11 and 12 years (l11.47), of the city of Limeira - SP. For the collection of the data three questionnaires had been applied, in which, questionnaire 1, were composed for questions about: sleep structure; health problems; medicine use; relationship in the family and with friends; personal habits; among others; questionnaire 2 (PAQ-C), was used to measure the level of regular physical activity and to classify the adolescents in sedentary or active; questionnaire 3, was structuralized and used to verify the subjective perception of the sleep quality. After, we apply the Qui-square test to verify if it had difference between the answers presented for the active and sedentary girls for the referring questions to questionnaire 1, and the relative question to the subjective perception of the sleep quality (questionnaire 3). Additionally, we use the residual analysis in the questions, where difference was found significant. This test was used to verify the behavior of the variable and categories, and to determine the variable that had more contributed for the joined difference. Test t for independent samples was applied to verify if it had difference between the schedule to sleep and to wake up, and the daily averages... (Complete abstract click electronic access below)

Orientador: Afonso Antonio Machado / Banca: Gisele Maria Schwartz / Banca: Fabiana Spina Martinelli / Resumo: Atualmente, nossa sociedade vem sofrendo uma transformação sem precedentes, no qual, a população, de uma maneira geral, tem se deparado com inúmeros distúrbios, sejam eles, de ordem: social, psicológica e biológica. Esses distúrbios têm refletido em uma menor qualidade de vida e saúde de nossa população, bem como, aumento nos níveis de estresse, diminuição na qualidade de sono, entre outros. Por outro lado, o exercício físico, e a Educação Física escolar vem sendo apontados como importantes agentes promotores de saúde. Pensando nisso, procuramos investigar a influência destas atividades, sobre a estrutura do sono de 58 alunas do sexo feminino, com idades entre 11 e 12 anos (l11.47), da cidade de Limeira – SP. Para a coleta dos dados foram aplicados três questionários, no qual, o questionário 1, foi composto por perguntas relativas: à estrutura de sono; problemas de saúde; uso de medicamentos; relacionamento familiar e com amigos; hábitos pessoais; entre outros; o questionário 2 (PAQ-C), foi utilizado para medir o nível de atividade física regular e classificar as adolescentes em ativas e sedentárias; o questionário 3, foi estruturado e utilizado para verificar a percepção subjetiva de qualidade de sono. Posteriormente, aplicamos o teste Qui-quadrado para verificar se havia diferença entre as respostas apresentadas pelas alunas ativas e sedentárias para as questões referentes ao questionário 1, e a questão relativa à percepção subjetiva de qualidade de sono (questionário 3). Adicionalmente, empregamos a análise residual nas questões, onde foi encontrada diferença significativa. Este teste foi utilizado para verificar o comportamento das variáveis e categorias, bem como, determinar as variáveis que mais contribuíram para a diferença encontrada. O teste t para amostras independentes foi aplicado para verificar se havia diferença... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Currently, our society has been suffering a transformation without precedents, in which, the population, in a general way, if has come across with innumerable disorders, is they, social, psychological and biological order. These disorders have reflected in a lesser life quality and health of our population, increase in the levels of stress, reduction in the sleep quality, among others. On the other hand, the physical exercise, and the Physical Education in school have been pointed as important promotional agents of health. Thinking about this, we decided to investigate the influence of these activities, on the structure of the sleep of 58 girls, with ages between 11 and 12 years (l11.47), of the city of Limeira - SP. For the collection of the data three questionnaires had been applied, in which, questionnaire 1, were composed for questions about: sleep structure; health problems; medicine use; relationship in the family and with friends; personal habits; among others; questionnaire 2 (PAQ-C), was used to measure the level of regular physical activity and to classify the adolescents in sedentary or active; questionnaire 3, was structuralized and used to verify the subjective perception of the sleep quality. After, we apply the Qui-square test to verify if it had difference between the answers presented for the active and sedentary girls for the referring questions to questionnaire 1, and the relative question to the subjective perception of the sleep quality (questionnaire 3). Additionally, we use the residual analysis in the questions, where difference was found significant. This test was used to verify the behavior of the variable and categories, and to determine the variable that had more contributed for the joined difference. Test t for independent samples was applied to verify if it had difference between the schedule to sleep and to wake up, and the daily averages... (Complete abstract click electronic access below) / Mestre

The serotonergic and cholinergic systems are jointly involved in regulating sleep but this balance is theorized to be disturbed in depressed individuals (Janowsky 1972, Jouvet 1972). One potential cause of disturbed neurotransmission is genetic predisposition. The G(-1019) allele of the 5-HT1A receptor predicts an increased risk for depression compared to the wild-type C(-1019) allele. The goal of this study was to use pharmacological probes in normal controls to model the serotonergic/cholinergic imbalance of depression and its associated abnormalities in sleep structure while controlling for 5-HT1A receptor genotype. Seventeen healthy female participants homozygous for either C (n=11) or G (n=6) alleles, age 18-27 years were tested on four non-consecutive nights. Participants were given galantamine (an anti-acetylcholinesterase), buspirone (a serotonergic agonist), both drugs together, or placebos before sleeping. Buspirone suppressed tonic REM: there was a significant increase in REM latency (p<0.001). Galantamine increased tonic REM sleep, leading to more time spent in stage REM (p<0.001) and shorter REM latency (p<0.01). Galantamine and buspirone given together tended to negate the effects of each other on REM sleep measures but disrupted sleep more than either drug alone, showing lower SE and N3% and increased awakenings, Wake% and N1% (p<0.019). There was no main effect of genotype nor was there a significant multivariate interaction between genotype and drug condition. These findings are partially consistent with the literature about sleep in depression, notably short REM latency, higher percentage of total sleep time spent in REM, and increased sleep fragmentation. The C/G mutation in the 5-HT1A receptor does not appear to cause noticeable differences in the sleep patterns of healthy young females.