京都大学 / 新制・課程博士 / 博士(教育学) / 甲第24988号 / 教博第297号 / 新制||教||221(附属図書館) / 京都大学大学院教育学研究科教育学環専攻 / (主査)教授 齊藤 智, 教授 MANALO Emmanuel, 准教授 高橋 雄介 / 学位規則第4条第1項該当 / Doctor of Philosophy (Education) / Kyoto University / DGAM

Insecticidal proteins from Bacillus thuringiensis (Bt) are used widely in sprays and transgenic plants to control insect pests. Although much research has elucidated the effects of Bt toxins on larvae, relatively little is known about their effects on adults. Here, we evaluated the effects of exposing adults to Bt toxin Cry1Ac on the life span and reproduction of two strains of pink bollworm (Pectinophora gossypiella (Saunders)). In larval diet bioassays, the concentration of Cry1Ac killing 50% of larvae (LC50) was 640 times higher for the laboratory-selected resistant strain (AZP-R) than the susceptible strain (APHIS-S). In experiments with adults, the highest concentrations of Cry1Ac tested (160 and 640 mu g Cry1Ac per ml of 5% honey water) reduced life span for both strains. Treatments with 10, 40, and 160 mg Cry1Ac per ml reduced the duration of the oviposition period as well as the number of eggs laid by both strains, but did not affect the percentage of pairs producing eggs, the duration of the preoviposition period, or the percentage of eggs hatching for either strain. Adult life span did not differ between strains at low to moderate concentrations of Cry1Ac, but it was significantly greater for the resistant strain than the susceptible strain at the two highest concentrations of Cry1Ac tested. The reduced susceptibility to high concentrations of Cry1Ac in adults of the AZP-R strain relative to the APHIS-S strain provides the first evidence of expression of resistance to a Bt toxin in adult Lepidoptera.

'Transient impressions' explores breaking and changing qualities in textiles. Sustainability and people’s relationship to textiles are discussed through decomposing and changing processes in textile material and through different life-spans of materials. The project proposes a way of working with textile material, where expressions are designed to change over different periods of time. / Program: Konstnärligt masterprogram i mode- oh textildesign

Cognitive research with human non-smokers has demonstrated that nicotine generally enhances performance on tasks of attention but, working memory does not appear to be affected. In contrast, nicotine has been shown to produce robust enhancements of working memory in non-human animals. To address this disparity, the present study investigated the effects of nicotine (2mg, 4mg nicotine gum, and placebo) on the performance of 30 non-smokers (15 male) completing a working memory task developed for rodents (the odor span task, OST). Nicotine has been reported to enhance OST performance in rodents and the present study sought to determine whether the effect is generalizable to human performance. In addition to completing the OST, participants completed a cognitive battery of clinical and experimental tasks assessing working memory and attention. This allowed for a direct comparison of OST performance to other commonly used measures of human cognition. Findings showed that nicotine was associated with dose dependent enhancements in sustained attention, as evidenced by increased hit accuracy on the rapid visual information processing (RVIP) task. However, nicotine failed to produce main effects on OST performance or on alternative measures of working memory (digit span, spatial span, letter-number sequencing, 2-back) or attention (digits forward, 0-back). Interestingly, enhancement of RVIP performance occurred concomitant to significant reductions in self-reported attention/concentration. Human OST performance was significantly related to N-back performance and, as in rodents, OST accuracy declined with increasing memory load. Given the similarity of human and rodent OST performance and the strong association observed between OST and visual 0-back accuracy, the OST may be particular useful for preclinical studies of conditions characterized by inattention.

In this work we deal with the nonlinear o.d.e u"+ku = εu³ which represents a spring-mass system with no damping but perturbed by external force εu³. We want to know how the spring constant k and the perturbed term act on the equation. So we study this equation by the way: (I) u" + ku = 0 (II)u" = u³ (III) u" + ku = εu³ During the period of calculating, we find that k, ε and energy constant E(0) play important roles in the properties of the solutions of the equation. Finally we give the relation about them.

<p>In phylogenetic analysis one study the relationship between different species. By comparing DNA from two different species it is possible to get a numerical value representing the difference between the species. For a set of species, all pair-wise comparisons result in a dissimilarity matrix <em>d</em>.</p><p>In this thesis I present a few methods for constructing a phylogenetic tree from <em>d</em>. The common denominator for these methods is that they do not generate a tree, but instead give a connected graph. The resulting graph will be a tree, in areas where the data perfectly matches a tree. When <em>d</em> does not perfectly match a tree, the resulting graph will instead show the different possible topologies, and how strong support they have from the data.</p><p>Finally I have tested the methods both on real measured data and constructed test cases.</p>

In phylogenetic analysis one study the relationship between different species. By comparing DNA from two different species it is possible to get a numerical value representing the difference between the species. For a set of species, all pair-wise comparisons result in a dissimilarity matrix d. In this thesis I present a few methods for constructing a phylogenetic tree from d. The common denominator for these methods is that they do not generate a tree, but instead give a connected graph. The resulting graph will be a tree, in areas where the data perfectly matches a tree. When d does not perfectly match a tree, the resulting graph will instead show the different possible topologies, and how strong support they have from the data. Finally I have tested the methods both on real measured data and constructed test cases.

Modern gas turbine engines require higher turbine-entry gas temperature to improve their thermal efficiency and thereby their performance. A major accompanying concern is the heat-up of the turbine components which are already subject to high thermal and mechanical stresses. This heat-up can be reduced by: (i) applying thermal barrier coating (TBC) on the surface, and (ii) providing coolant to the surface by injecting secondary air discharged from the compressor. However, as the bleeding off of compressor discharge air exacts a penalty on engine performance, the cooling functions must be accomplished with the smallest possible secondary air injection. This necessitates a detailed and systematic study of the various flow and geometrical parameters that may have a bearing on the cooling pattern. In the present study, experiments were performed in three regions of a non-rotating gas turbine blade cascade: blade platform, blade span, and blade tip. The blade platform and blade span studies were carried out on a high pressure turbine rotor blade cascade in medium flow conditions. Film-cooling effectiveness or degree of cooling was assessed in terms of cooling hole geometry, blowing ratio, freestream turbulence, coolant-to-mainstream density ratio, purge flow rate, upstream vortex for blade platform cooling and blowing ratio, and upstream vortex for blade span cooling. The blade tip study was performed in a blow-down flow loop in a transonic flow environment. The degree of cooling was assessed in terms of blowing ratio and tip clearance. Limited heat transfer coefficient measurements were also carried out. Mainstream pressure loss was also measured for blade platform and blade tip film-cooling with the help of pitot-static probes. The pressure sensitive paint (PSP) and temperature sensitive paint (TSP) techniques were used for measuring film-cooling effectiveness whereas for heat transfer coefficient measurement, temperature sensitive paint (TSP) technique was employed. Results indicated that the blade platform cooling requires a combination of upstream purge flow and downstream discrete film-cooling holes to cool the entire platform. The shaped cooling holes provided wider film coverage and higher film-cooling effectiveness than the cylindrical holes while also creating lesser mainstream pressure losses. Higher coolant-to-mainstream density ratio resulted in higher effectiveness levels from the cooling holes. On the blade span, at any given blowing ratio, the suction side showed better coolant coverage than the pressure side even though the former had two fewer rows of holes. Film-cooling effectiveness increased with blowing ratio on both sides of the blade. Whereas the pressure side effectiveness continued to increase with blowing ratio, the increase in suction side effectiveness slowed down at higher blowing ratios (M=0.9 and 1.2). Upstream wake had a detrimental effect on film coverage. 0% and 25% wake phase positions significantly decreased film-cooling effectiveness magnitude. Comparison between the compound shaped hole and the compound cylindrical hole design showed higher effectiveness values for shaped holes on the suction side. The cylindrical holes performed marginally better in the curved portion of the pressure side. Finally, the concept tip proved to be better than the baseline tip in terms of reducing mainstream flow leakage and mainstream pressure loss. The film-cooling effectiveness on the concept blade increased with increasing blowing ratio and tip gap. However, the film-coverage on the leading tip portion was almost negligible.

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¡@¡@This study aims to investigate the theories and empirical performance of the futures and options margin systems currently used in the domestic and international exchange houses. The current system used in Taiwan Futures Exchange (TAIFEX) is strategy-based rather than portfolio-based or and contract risk-based. It is no longer compliant with the development of the futures market. Therefore, it is suggested that TAIFEX should employ international experiences to adopt a portfolio-based and VaR-based margin system so as to meet the need of the local trading feature that portfolios contain both stock futures and stock options. ¡@¡@This study integrates scenario simulation and the diagonal model to propose a new model, called Beta-Simulation, to calculate the margins for portfolios containing stock options, index futures, and stocks. The proposed model can not only simplify the inter-commodity spread in SPAN but also theoretically improve the drawback of TIMS of using a simple credit offset multiplier. In the empirical test, back testing is performed on the margins calculated by Beta-Simulation with historic data of portfolios with stock options, and other common margin systems are also included in the test for comparison. ¡@¡@The empirical results reveal that only SPAN and Beta-Simulation can save approximately 12%~42% margin requirements for portfolios containing stock options, but under the same protection degree, Beta-Simulation requires significantly lower margins and a simpler calculation process than SPAN. Therefore, the proposed model is a better model of calculating margins and VaR for portfolios containing stock options.