Thesis (M.S.)--University of Michigan, 1963.

Thesis (M.S.)--Ohio State University, 2006. / Includes bibliographical references (leaves 99-109). Available online via OhioLINK's ETD Center

Thesis (Ph. D.)--University of Washington, 2006. / Vita. Includes bibliographical references (leaves 82-88).

Thesis (PhD) - Environment and Biotechnology Centre, Faculty of Life and Social Sciences, Swinburne University of Technology, 2009. / Submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy, Environment and Biotechnology Centre, Faculty of Life and Social Sciences, Swinburne University of Technology, 2009. Typescript. Bibliography: p. 223-240.

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This study is to investigate that the polishing behavior will be independent of or dependent on the direction of particle motion by the anisotropic polishing phenomenon of hydrodynamic polishing process under the semi-contact lubricating condition. There are two types of experiments to be examined to get to the objectives. First, taking polishing on the work surface which possesses the isotropic surface roughness, to discuss the variation of the smoothing efficiency of the surface irregularities in the five different directions on the work surface. Second, taking three kinds of polishing, ¡§longitudinal, transverse, and oblique roughness polishing¡¨, on the work surface which possesses the anisotropic surface roughness. Then to discuss the variation of the smoothing efficiency of the surface irregularities on the work surface. Both the results of two types experiments should be take to distinguish the difference between one smoothing efficiency and the others from using the hypothesis testing. All hypothesis tests about the experiment results of the work piece which possesses the isotropic surface roughness are accepting . But, most hypothesis tests about the experiment results of the work piece which possesses the anisotropic surface roughness are rejecting . The theory analysis about the smoothing efficiency is discussing. The discussion about the smoothing efficiency can explain the phenomenon due to taking polishing on the work surface which possesses the anisotropic surface roughness. The reason why the phenomenon happened is possible the effects of different lubrication condition. Last, from the lubrication theory, the effects of different lubrication condition due to different surface texture can be employed to verify the explanation about the phenomenon is suitable. The conclusion from the experiment results and the theory analysis is: the polishing behavior is possible independent of the direction of particle motion by the anisotropic polishing phenomenon of hydro- dynamic polishing process under the semi-contact lubricating condition.

The ultimate value of surface roughness and its characteristic for the polishing process was investigated in this thesis. To find out the nature of ultimate surface roughness by means of the hydrodynamic polishing process and can be used for all polishing method. A preliminary mathematical model that was proposed to explain the ultimate surface roughness proceedings and a series of experiments was planed to verify suitable of this model. Starting with the rule for ultimate surface roughness happened. The assumption that abrasive particle at roughness peak and valley machining capability differ less than one atom, the ultimate surface roughness be attained. We can propose the mathematical model of ultimate surface roughness based on this rule and the previous study of hydrodynamic polishing process. Following by useing the computer simulation to help us exploring ultimate surface roughness characteristic and testing experiments fit for the forecasting. Finally, we explain reasons that cause the experiment results not agree with the model anticipation and propose better lubrication condition to polish the optimum surface.

This university Bachelor's Thesis was performed to explore the influence of surface roughness on the thermography measurement. Thermography is a non-destructive testing method which can be used to detect cracks. However, it is hard to define how the surface roughness influences the emissivity and the result of a thermography measurement, as well as how the angle of the excitation source influences the result. Therefore, this work aims to define how the heating angle and surface roughness influence the thermography measurement, define the relationship between surface roughness and emissivity for the same crack, and define the influence of the angles which composed of the heating source, the direction of crack and the direction of surface roughness on thermography measurement. In this report, the theories of radiation and Signal-to-noise ratio (SNR) were explained, clearly. Also, two kinds of experiments were set up. One is focus on how the heating angle influence the thermography measurement, the other is focus on how the angle of the heating source, in relation to the crack direction and the direction of surface roughness, influence the SNR value. The conclusions of these experiments are that the heating of a crack increases as the angle decreases (from wide side to narrow side) and the angle ofincreases (from horizontal to vertical). Moreover, the SNR value decreases as the surface roughness increases. For the same surface roughness, the SNR value increases with increased crack angle (0°, 45° or 90°) and with decreased sample position angle (horizontal, 45°or vertical). What is more, the higher surface roughness, the larger the influence of the crack angle and the sample position angle. Finally, when the surface is polish, the crack angle and the sample position angle does not have any influence.

Physical stress such as the surface roughness of the implants may activate the NFkB signalling pathway in macrophages. This activation is intimately related to the mechanism(s) by which the macrophage interacts with the surface through serum proteins and/or the formation of membrane rafts. This thesis examines the role of surface topography on activation of the NFkB signalling pathway in macrophages. We examined the effect of implant surface topography on activating the NFkB signalling pathway in the RAW 264.7 macrophage cell line. We also examined the effect surface roughness had on the adhesion of the macrophages using the different media. To finish, we observed the effect the different media and the surface roughness had on the morphology of the macrophages by Scanning Electron Microscopy. Activation of the NFkB pathway was surface topography dependent. The Smooth surface showed the highest level of activation followed by the Etched then the SLA. Addition of suboptimal concentrations of LPS mildly enhanced the response by signalling through the Toll receptor. Activation of NFKB occurred in the absence of fetal calf sera, although to a lesser extent. All three surfaces had very few cells with nuclear translocation at the 5 minutes time point with no significant statistical differences between the surfaces. After 30 minutes, translocation reached comparable levels to those surfaces tested with complete medium. Disruption of the lipid rafts affected the triggering and signalling of the NFkB pathway. This inhibitory effect was concentration and time dependent. Smooth surfaces bound more macrophages in the 30 minutes assay. Fetal calf serum appeared to be very critical for adhesion and spreading of the macrophages on the various surfaces examined. Removal of cholesterol did not affect adhesion or spreading on their respective surfaces. We have clearly demonstrated that the lipid rafts along with surface topography play a role in the activation on NFKB. This in-vitro study has demonstrated that surface topography modulated activation of the NFKB signalling pathway in a time-dependent manner. However, at present, it is unclear through which receptor(s) / surface structure the signal pathway is initiated.

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