Thesis (Doctoral)--Ludwig-Maxilians-Universität zu München, 1935.

Thesis (M. Sc.)--University of Manitoba, 1994. / Includes bibliographical references.

Thesis (doctoral)--Goteborgs Universitet, 1974. / Includes bibliographical references (p. 36-40).

Diss. Naturwiss. ETH Zürich, Nr. 6945, 0000. Ref.: Leisinger, T. ; Korref.: Guggenheim, B.

Thesis (doctoral)--Goteborgs Universitet, 1974. / Includes bibliographical references (p. 36-40).

Thesis (doctoral)--Münster in Westfalen, 1933.

Thesis (M.S.) -- Virginia Commonwealth University, 2003. / Title from title-page of electronic thesis. Prepared for: Dept. of Endodontics. Bibliography: p. 16-18.

Orientador: Lourdes Aparecida Martins dos Santos Pinto / Banca: Fernanda Lopez Rossell / Banca: Maria Cristina Borsatto / Resumo: Os objetivos deste estudo foram: observar a evolução clínica dos pacientes com HMI, para estabelecer a relação entre a sua severidade com fatores socioeconômicos, índice CPO-D e a presença de DDE, avaliar a evolução clínica do dente afetado por HMI, para estabelecer a relação com a presença de cárie, necessidade de tratamento e a ocorrência de perdas estruturais. Foram acompanhados 49 pacientes com HMI com idade entre 6 e 9 anos, totalizando 588 molares e incisivos com e sem alterações, que receberam tratamento preventivo e proteção com CIV quando indicados. As coletas de dados foram realizadas ao longo de 1 ano, com intervalos de 6 meses por meio de exame clínico, moldagem e fotografias. Um questionário semi-estruturado foi respondido pelas mães a fim de identificar a renda familiar, a escolaridade dos responsáveis e a fonte de água consumida. A análise descritiva, o teste Exato de Fisher, Qui-quadrado, McNemar e análise de sobrevida pelo método Kaplan-Meier foram usados para demonstrar os resultados encontrados. Houve uma associação significante entre o agravamento da HMI e o aumento do CPO-D. O nível sócio-econômico do paciente e a presença de DDE na dentição decídua não foram fatores relacionados à severidade. As fraturas pós-eruptivas ocorreram em 7 dos dentes afetados por manchas de HMI. Das restaurações acompanhadas, 16 apresentaram fratura, ocorridas todas nos primeiros molares permanentes. A presença de HMI apresentou estreita relação com a necessidade de tratamento e com o índice CPO-D. Com a grande possibilidade da estrutura afetada por HMI se manter hígida, 95% para manchas e 77% para restaurações atípicas, não se justifica a remoção, por completo ou prematuramente, da área afetada / Abstract: The goals of this study were to evaluate the clinic prognostic of patients with molar-incisor-hypomineralization (MIH), to establish the relation between its severity with socioeconomic background factors, DMTF index and the presence of dental enamel defects (DED), evaluate the clinical progress of the tooth affected by that injury, to establish the relation with the presence of dental decay, treatment needs and the occurrence of structural lost. The sample was constituted by 49 patients with HMI aging from 6 to 9 years old. This sample presented 588 molars and incisors teeth with and without abnormalities, which received preventive treatment and protection with conventional glass ionomer cement (GIC) when indicated. The data were collected along of one year with one period of 6 month of interval to clinical exam, impressions and intrabucal photographs. A semi-structured questionnaire was answered by the main guardians aimed to identify the family income, level of schooling and the source of water intake. The descriptive analysis, Fisher Exact test, Quis-square, McNemar and the Kaplan-Meier method (survive analysis) were performed. As results, there was a significant association between the MIH progression with the increase of DMTF index. The patient socioeconomic status and the presence of DED in the primary dentition were not the main factors related to severity. There were 7 post eruptive fractures in the group with MIH spots. Of all restored teeth, 16 first permanent molars presented fractures. The presence of MIH showed a close relation with the need of treatment and with the DMTF index. The results showed a high index of success of this treatment in maintain the sound structure of the teeth affected by HMI with 95% related to spots and 77% to atypical restorations procedures. Thus, remove the affected structure completely or prematurely is not a justified clinical decision / Mestre

Abstract The effects of dietary sucrose and systemic glucocorticoid treatment on the response of the pulpodentinal complex to dental caries were examined in an experimental rat model. The possible role of dentinal caries on dentin formation was also examined. After 5-6 weeks of a dietary and/or medication period, the areas of dentin formation and dentinal caries were quantified in the molars of growing animals. Also the number and severity of caries lesions were estimated. The 43% sucrose diet significantly reduced dentin formation and increased dentinal caries progression. Although glucocorticoid medication alone reduced dentin formation, without dietary sucrose it did not have an effect on caries. In combination of these two, glucocorticoids further increased the progression of dentinal caries, however without significant increase in the number of caries lesions. The cariogenic bacterial inoculation of rats fed a sucrose or control diet increased the progression of dentinal caries. The relationship between cariogenic bacteria and caries was not strong, but there was a stronger relationship between the total amount of dietary sucrose and dentinal caries. In addition to the overall reduction of dentin formation there was no difference in the amount of dentin formed between intact and carious fissures in the sucrose diet group. On the contrary, rats receiving the control diet positively responded to the dentinal caries by increasing dentin formation to prevent pulpal exposure. Whereas the high sucrose diet impaired both the deposition and mineralization of the dentin matrix, glucocorticoids affected matrix formation only. These results indicate that the functional alterations in the pulpo-dentinal complex might contribute to dentinal caries progression in a cariogenic environment, irrespective of the causative mechanism.

At an annual cost of over three billion dollars, surgical extraction of third molars is by far the most performed surgical procedure in the United States; however, there is and has been much controversy in the literature over the last several decades about the practicality of this procedure. Presently, professionals are divided on the issue of whether or not surgical extraction is necessary for asymptomatic disease free third molars. This comprehensive literature review was performed to investigate the current evidence concerning the prophylactic removal of third molars. It was discovered that many several journals, particularly those pertaining to oral and maxillofacial surgery has been hugely instrumental in marketing this procedure to the public through research articles. Close analysis of the literature revealed a significant level of inconsistency relating to study design, sample size, and methodology. In conclusion, for the typical prophylactic third molar extraction, the risk of complications are often underestimated while the potential gains in quality of life may be exaggerated which will impede the decision making process for the clinician and patient. For an elected surgery that is performed at such a grand scale, there are too many variables still unclear in the literature, many of which present as a public health hazard. There are also many other factors, both physically and ethically, that need to be considered before a responsible decision can be made. It was also found that the imaging technology currently being used as the standard of care for the diagnosis and treatment planning of third molars does not give a clear enough picture to ensure a complication-free surgery. Furthermore, there are other non-invasive options for the management of asymptomatic third molars that are not being applied enough, which do not require sacrificing the third molars. Complications resulting from third molar surgery are one of the most common reasons responsible for lawsuits facing dentists today and can also result in a lifetime of pain and disability for the patient. Taken together, the high cost of surgery along with the risk of complications following an otherwise disease-free third molar doesn't seem to be representative of responsible dentistry. More conservative approaches along with a general shift towards evidence-based dentistry may be the answer for the proper management of third molars. Discouraging the practice of prophylactic removal of third molars could result in billions of dollars in saving, elimination of millions of days of discomfort, and prevention of permanent injury to tens of thousands of people.