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Assessing the perceived impact of computer-assisted instruction on physical therapy educationErickson, Mia L. January 1900 (has links)
Thesis (Ed. D.)--West Virginia University, 2002. / Title from document title page. Document formatted into pages; contains xi, 178 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 151-160).
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Effects of feedback on recovery of pointing movements in two training environments in stroke : a pilot studySubramanian, Sandeep. January 2007 (has links)
Virtual reality environments (VEs) are new tools to improve functional recovery in stroke survivors. Elements essential to maximize motor learning, can be optimized in VEs. Study objectives were: (a) to determine whether training in VE with enhanced feedback about movement patterns, leads to greater gains in arm movement quality, motor performance and decreased compensation compared to training in a similarly designed Physical environment (PE); (b) to estimate whether impairments in cognitive functioning affected the changes observed after training. Twelve stroke survivors practiced 72 pointing movements in VE or PE for 10 sessions with enhanced feedback. Kinematic analysis of pointing task, evaluations of arm impairment and function were carried out pre-post training. After training, VE group had increased shoulder flexion (p<0.05), increased shoulder horizontal adduction and decreased compensation, compared to PE group. Use of feedback correlated with fewer deficits in cognitive functioning. Training in VEs may lead to greater gains in movement quality.
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Effects of feedback on recovery of pointing movements in two training environments in stroke : a pilot studySubramanian, Sandeep. January 2007 (has links)
No description available.
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Aplicabilidade do Software Auxiliar na Reabilitação de Distúrbios Auditivos (SARDA) em crianças com deficiência auditiva / Applicability of SARDA (Hearing Disorders Rehabilitation Auxiliary Software) in children with hearing impairmentSilva, Mariane Perin da 15 July 2011 (has links)
A utilização do computador na terapia fonoaudiológica faz parte do processo terapêutico, possibilitando o treinamento das habilidades auditivas por meio de softwares. Para tanto, esta pesquisa teve como objetivo verificar a aplicabilidade do Software Auxiliar na Reabilitação de Distúrbios Auditivos (SARDA) em crianças com deficiência auditiva. A amostra foi formada por 17 crianças com deficiência auditiva, sendo 10 usuárias de Implante Coclear (IC) e sete usuárias de Aparelho de Amplificação Sonora Individual (AASI). O estudo foi realizado em três etapas: 1) avaliação da percepção da fala no silêncio e no ruído; 2) 30 minutos de estimulação com o SARDA, duas vezes por semana, durante o tempo necessário para a criança finalizar as estratégias; 3) reavaliação dos quesitos testados na primeira etapa. O teste de percepção da fala utilizado foi o Hearing in Noise Test (HINT). Para a análise estatística dos dados foram utilizados os testes t de Student para dados pareados e independentes e o teste de Correlação de Pearson. As crianças usuárias de IC necessitaram em média 12,2 dias para a finalizarem os jogos e as crianças usuárias de AASI em média 10,14 dias. Os dois grupos apresentaram diferença estatisticamente significante entre as avaliações pré e pós no silêncio e no ruído. A média do Limiar de Reconhecimento de Sentenças (LRS) do grupo de usuários de IC foi de 62,5 dB na avaliação pré e 55,28 dB na avaliação pós e a média da relação Sinal/Ruído (S/R) foi de 5,19 dB na avaliação pré e 1,34 dB na avaliação pós. A média do LRS do grupo de usuários de AASI foi de 61,8 dB na avaliação pré e 55,27 dB na avaliação pós e a relação S/R foi de 5,89 dB na avaliação pré e 2,43 dB na avaliação pós. Na análise do desempenho das crianças nas estratégias, notou-se uma gradativa diminuição no tempo dispensado para a conclusão das etapas. As crianças mais novas necessitaram de mais tempo para a conclusão do treinamento ou não conseguiram finalizar as estratégias; contudo, não houve correlação estatística entre a idade e o desempenho nas estratégias. Pode-se concluir que o treinamento auditivo com o SARDA foi eficaz, pois os resultados indicaram uma melhora da habilidade de percepção da fala no silêncio e no ruído das crianças com deficiência auditiva. / The use of computers in audio and speech therapy is part of the therapeutic process, enabling the training of auditory skills through software. Thus, this study aimed at verifying the applicability of SARDA (Hearing Disorders Rehabilitation Auxiliary Software) in children with hearing impairment. The sample comprised 17 children with hearing impairment, being 10 users of a Cochlear Implant (CI) and seven users of a Hearing Aid (HA). The study was carried out in three phases: 1) speech perception assessment in silence and noise; 2) 30 minutes of SARDA stimulation, twice a week, during the necessary time for the child to finish the strategies; 3) reassessment of the requirements tested in the first phase, being the Hearing in Noise Test (HINT), the speech perception test utilized. Student´s t test, for paired and independent data, and Pearson´s Correlation test, were used in the statistical analysis. The children fitted with a CI needed, in average, 12.2 days to finish the games, and those using a HA, 10.14 days. The two groups presented a statistically significant difference between pre and post-assessments in silence and noise. The mean of Sentence Recognition Threshold (SRT) for the group of CI users was 62.5 dB in the pre-assessment and 55.28 dB in the post-assessment; the mean for signal to noise (S/N) ratio was 5.19 dB in the pre and 1.34 dB in the post-assessment. The mean SRT for the group of HA users was 61.8 dB in the pre and 55.27 dB in the post-assessment and the S/N ratio was 5.89 dB in the pre and 2.43 dB in the post-assessment. The analysis of how the children performed in the strategies, showed a gradual decrease in the time spent to complete the phases. Younger children needed more time to finish the training or were unable to complete the strategies; nevertheless, no statistical correlation between age and the performance in the strategies was seen. It can be concluded that the auditory training with SARDA was effective, for the results showed an improvement in the speech perception skills, in silence and in noise, for the children with hearing impairment.
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Aplicabilidade do Software Auxiliar na Reabilitação de Distúrbios Auditivos (SARDA) em crianças com deficiência auditiva / Applicability of SARDA (Hearing Disorders Rehabilitation Auxiliary Software) in children with hearing impairmentMariane Perin da Silva 15 July 2011 (has links)
A utilização do computador na terapia fonoaudiológica faz parte do processo terapêutico, possibilitando o treinamento das habilidades auditivas por meio de softwares. Para tanto, esta pesquisa teve como objetivo verificar a aplicabilidade do Software Auxiliar na Reabilitação de Distúrbios Auditivos (SARDA) em crianças com deficiência auditiva. A amostra foi formada por 17 crianças com deficiência auditiva, sendo 10 usuárias de Implante Coclear (IC) e sete usuárias de Aparelho de Amplificação Sonora Individual (AASI). O estudo foi realizado em três etapas: 1) avaliação da percepção da fala no silêncio e no ruído; 2) 30 minutos de estimulação com o SARDA, duas vezes por semana, durante o tempo necessário para a criança finalizar as estratégias; 3) reavaliação dos quesitos testados na primeira etapa. O teste de percepção da fala utilizado foi o Hearing in Noise Test (HINT). Para a análise estatística dos dados foram utilizados os testes t de Student para dados pareados e independentes e o teste de Correlação de Pearson. As crianças usuárias de IC necessitaram em média 12,2 dias para a finalizarem os jogos e as crianças usuárias de AASI em média 10,14 dias. Os dois grupos apresentaram diferença estatisticamente significante entre as avaliações pré e pós no silêncio e no ruído. A média do Limiar de Reconhecimento de Sentenças (LRS) do grupo de usuários de IC foi de 62,5 dB na avaliação pré e 55,28 dB na avaliação pós e a média da relação Sinal/Ruído (S/R) foi de 5,19 dB na avaliação pré e 1,34 dB na avaliação pós. A média do LRS do grupo de usuários de AASI foi de 61,8 dB na avaliação pré e 55,27 dB na avaliação pós e a relação S/R foi de 5,89 dB na avaliação pré e 2,43 dB na avaliação pós. Na análise do desempenho das crianças nas estratégias, notou-se uma gradativa diminuição no tempo dispensado para a conclusão das etapas. As crianças mais novas necessitaram de mais tempo para a conclusão do treinamento ou não conseguiram finalizar as estratégias; contudo, não houve correlação estatística entre a idade e o desempenho nas estratégias. Pode-se concluir que o treinamento auditivo com o SARDA foi eficaz, pois os resultados indicaram uma melhora da habilidade de percepção da fala no silêncio e no ruído das crianças com deficiência auditiva. / The use of computers in audio and speech therapy is part of the therapeutic process, enabling the training of auditory skills through software. Thus, this study aimed at verifying the applicability of SARDA (Hearing Disorders Rehabilitation Auxiliary Software) in children with hearing impairment. The sample comprised 17 children with hearing impairment, being 10 users of a Cochlear Implant (CI) and seven users of a Hearing Aid (HA). The study was carried out in three phases: 1) speech perception assessment in silence and noise; 2) 30 minutes of SARDA stimulation, twice a week, during the necessary time for the child to finish the strategies; 3) reassessment of the requirements tested in the first phase, being the Hearing in Noise Test (HINT), the speech perception test utilized. Student´s t test, for paired and independent data, and Pearson´s Correlation test, were used in the statistical analysis. The children fitted with a CI needed, in average, 12.2 days to finish the games, and those using a HA, 10.14 days. The two groups presented a statistically significant difference between pre and post-assessments in silence and noise. The mean of Sentence Recognition Threshold (SRT) for the group of CI users was 62.5 dB in the pre-assessment and 55.28 dB in the post-assessment; the mean for signal to noise (S/N) ratio was 5.19 dB in the pre and 1.34 dB in the post-assessment. The mean SRT for the group of HA users was 61.8 dB in the pre and 55.27 dB in the post-assessment and the S/N ratio was 5.89 dB in the pre and 2.43 dB in the post-assessment. The analysis of how the children performed in the strategies, showed a gradual decrease in the time spent to complete the phases. Younger children needed more time to finish the training or were unable to complete the strategies; nevertheless, no statistical correlation between age and the performance in the strategies was seen. It can be concluded that the auditory training with SARDA was effective, for the results showed an improvement in the speech perception skills, in silence and in noise, for the children with hearing impairment.
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A cone-beam computerized tomography evaluation of anterior root resorption comparing SureSmile® and conventional edgewise treatmentsPatel, Neepa. January 2009 (has links) (PDF)
Thesis--University of Oklahoma. / Bibliography: leaves 120-128.
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Knowledge-based IMRT treatment planning for prostate cancer.Chanyavanich, V, Das, SK, Lee, WR, Lo, JY 05 1900 (has links)
PURPOSE: To demonstrate the feasibility of using a knowledge base of prior treatment plans to generate new prostate intensity modulated radiation therapy (IMRT) plans. Each new case would be matched against others in the knowledge base. Once the best match is identified, that clinically approved plan is used to generate the new plan. METHODS: A database of 100 prostate IMRT treatment plans was assembled into an information-theoretic system. An algorithm based on mutual information was implemented to identify similar patient cases by matching 2D beam's eye view projections of contours. Ten randomly selected query cases were each matched with the most similar case from the database of prior clinically approved plans. Treatment parameters from the matched case were used to develop new treatment plans. A comparison of the differences in the dose-volume histograms between the new and the original treatment plans were analyzed. RESULTS: On average, the new knowledge-based plan is capable of achieving very comparable planning target volume coverage as the original plan, to within 2% as evaluated for D98, D95, and D1. Similarly, the dose to the rectum and dose to the bladder are also comparable to the original plan. For the rectum, the mean and standard deviation of the dose percentage differences for D20, D30, and D50 are 1.8% +/- 8.5%, -2.5% +/- 13.9%, and -13.9% +/- 23.6%, respectively. For the bladder, the mean and standard deviation of the dose percentage differences for D20, D30, and D50 are -5.9% +/- 10.8%, -12.2% +/- 14.6%, and -24.9% +/- 21.2%, respectively. A negative percentage difference indicates that the new plan has greater dose sparing as compared to the original plan. CONCLUSIONS: The authors demonstrate a knowledge-based approach of using prior clinically approved treatment plans to generate clinically acceptable treatment plans of high quality. This semiautomated approach has the potential to improve the efficiency of the treatment planning process while ensuring that high quality plans are developed. / Dissertation
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Redução automática versus manual da pressão de suporte no desmame de pacientes em pós-operatório: estudo controlado e randomizado / Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomized controlled trialTaniguchi, Corinne 29 September 2008 (has links)
INTRODUÇÃO: A redução automática da pressão de suporte (PS) baseada na freqüência respiratória, ou MRV (mandatory rate ventilation) é um modo ventilatório disponível no ventilador Taema-Horus. A hipótese do estudo é que o MRV utilizado no desmame é tão efetivo quanto o desmame manual em pacientes em pós-operatório na unidade de terapia intensiva (UTI). MÉTODOS: Ao chegar à UTI, após a cirurgia, os pacientes eram randomizados em dois grupos: desmame manual ou automático. O desmame manual consistiu na redução manual da PS a cada 30 minutos mantendo a relação freqüência respiratória sobre volume corrente menor do que 80, até a PS de 5-7 cmH2O. O desmame automático baseou-se na freqüência respiratória alvo de 15 respirações por minuto (o ventilador diminui automaticamente, a PS em 1 cmH2O a cada 4 ciclos respiratórios, se o paciente mantiver a freqüência respiratória abaixo deste valor). O objetivo primário do estudo foi comparar a duração do processo de desmame. Secundariamente verificamos o nível de PS, freqüência respiratória, volume corrente, índice de freqüência respiratória sobre volume corrente, pressão positiva expiratória final, fração inspirada de oxigênio e saturação de oxigênio requeridos durante o processo de desmame. Verificamos também necessidade de reintubação e necessidade de ventilação não invasiva nas primeiras 48 horas após a extubação. RESULTADOS: Não houve diferença estatística significativa entre os 53 pacientes selecionados em cada grupo quanto ao sexo (p=0541), idade (p=0,585) e tipo de cirurgia (p=0,172). Dezenove pacientes foram excluídos durante o protocolo (quatro no grupo manual e quinze no grupo automático, p<0,05). Nove pacientes do grupo automático foram excluídos do protocolo por não se adaptarem ao modo de desmame automático. Oitenta e sete pacientes concluíram o estudo, quarenta e nove pacientes foram desmamados manualmente e trinta e oito automaticamente. A duração do processo de desmame foi de 205,41±181,27 minutos (de 30 a 840 minutos) no grupo manual, e 157,33±129,98 minutos (de 30 a 545 minutos) no grupo automático. Não houve diferença estatística significante quanto ao tempo de desmame entre os dois grupos. O nível de PS foi maior (p<0,001) e freqüência respiratória foi menor (p=0,0098) no modo MRV comparado ao modo manual, durante o processo de desmame. Não houve necessidade de reintubação em nenhum dos grupos. Houve necessidade de ventilação não invasiva em dois pacientes do grupo manual (p=0,505), ambos sofreram cirurgia cardíaca. CONCLUSÃO: A redução automática da PS foi efetiva e pode ser utilizada no desmame de pacientes no pós-operatório na unidade de terapia intensiva, se o paciente se adaptar ao algoritmo do MRV / Introduction: Automatic pressure support reduction based on a target respiratory frequency or MRV is available in the TAEMA-HORUS ventilator for the weaning process in the ICU setting. We hypothesized that MRV is as effective as manual weaning in post-operative ICU patients. Methods: There were 106 patients selected, in the post-operative period in a prospective, randomized, controlled protocol. When the patients arrived in the ICU after surgery, they were randomly assigned to traditional weaning, consisted of the manual reduction of pressure support every thirty minutes, keeping the RR/TV(L) < 80 till 5-7 cmH20 of PSV. Alternatively, they were assigned to automatic weaning, referring to MRV set with a respiratory frequency target of 15 breaths per minute (the ventilator automatically decreased the PSV level by 1 cmH20 every 4 respiratory cycles, if the patients RR was less than 15 per minute). The primary endpoint of the study was the duration of the weaning process. Secondary endpoints were levels of pressure support, respiratory rate, tidal volume (mL), RR/VT (L), PEEP levels FiO2 and SpO2 required during the weaning process, the need for reintubation and the need for non-invasive ventilation in the 48 hours after extubation. Results: There were no statistically significant differences between the 53 patients selected for each group regarding gender (p=0.541), age (p=0.585) and type of surgery (p=0.172). Nineteen patients were excluded during the trial (4 in the PSV group and 15 in the MRV group, p<0.05). Eighty-seven patients concluded the study, forty-nine patients were weaned manually and thirtyeight automatically. The weaning duration process was 205.41 ± 181.27 minutes (30 to 840 minutes) for the manual group and 157. 33± 129.98 minutes (30 to 545 minutes) for MRV group (p=0.167). PSV levels were significantly higher and RR was lower in MRV compared to that of the PSV manual reduction (p<0.05). Reintubation was not required in either group. NIV was necessary for two patients, in the manual group after cardiac surgery (p=0.505). Conclusion: The automatic reduction of pressure support was effective and can be useful for weaning patients in the post-operative period in the ICU, if the patient is receptive to the MRV algorithm
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Applications of evolutionary algorithms on biomedical systems.January 2007 (has links)
Tse, Sui Man. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2007. / Includes bibliographical references (leaves 95-104). / Abstracts in English and Chinese. / Abstract --- p.i / Acknowledgement --- p.v / Chapter 1 --- Introduction --- p.1 / Chapter 1.1 --- Motivation --- p.1 / Chapter 1.1.1 --- Basic Concepts and Definitions --- p.2 / Chapter 1.2 --- Evolutionary Algorithms --- p.5 / Chapter 1.2.1 --- Chromosome Encoding --- p.6 / Chapter 1.2.2 --- Selection --- p.7 / Chapter 1.2.3 --- Crossover --- p.9 / Chapter 1.2.4 --- Mutation --- p.10 / Chapter 1.2.5 --- Elitism --- p.11 / Chapter 1.2.6 --- Niching --- p.11 / Chapter 1.2.7 --- Population Manipulation --- p.13 / Chapter 1.2.8 --- Building Blocks --- p.13 / Chapter 1.2.9 --- Termination Conditions --- p.14 / Chapter 1.2.10 --- Co-evolution --- p.14 / Chapter 1.3 --- Local Search --- p.15 / Chapter 1.4 --- Memetic Algorithms --- p.16 / Chapter 1.5 --- Objective --- p.17 / Chapter 1.6 --- Summary --- p.17 / Chapter 2 --- Background --- p.18 / Chapter 2.1 --- Multiple Drugs Tumor Chemotherapy --- p.18 / Chapter 2.2 --- Bioinformatics --- p.22 / Chapter 2.2.1 --- Basics of Bioinformatics --- p.24 / Chapter 2.2.2 --- Applications on Biomedical Systems --- p.26 / Chapter 3 --- A New Drug Administration Dynamic Model --- p.29 / Chapter 3.1 --- Three Drugs Mathematical Model --- p.31 / Chapter 3.1.1 --- Rate of Change of Different Subpopulations --- p.32 / Chapter 3.1.2 --- Rate of Change of Different Drug Concen- trations --- p.35 / Chapter 3.1.3 --- Toxicity Effects --- p.35 / Chapter 3.1.4 --- Summary --- p.36 / Chapter 4 --- Memetic Algorithm - Iterative Dynamic Program- ming (MA-IDP) --- p.38 / Chapter 4.1 --- Problem Formulation: Optimal Control Problem (OCP) for Mutlidrug Optimization --- p.38 / Chapter 4.2 --- Proposed Memetic Optimization Algorithm --- p.40 / Chapter 4.2.1 --- Iterative Dynamic Programming (IDP) . . --- p.40 / Chapter 4.2.2 --- Adaptive Elitist-population-based Genetic Algorithm (AEGA) --- p.44 / Chapter 4.2.3 --- Memetic Algorithm 一 Iterative Dynamic Programming (MA-IDP) --- p.50 / Chapter 4.3 --- Summary --- p.56 / Chapter 5 --- MA-IDP: Experiments and Results --- p.57 / Chapter 5.1 --- Experiment Settings --- p.57 / Chapter 5.2 --- Optimization Results --- p.61 / Chapter 5.3 --- Extension to Other Mutlidrug Scheduling Model . --- p.62 / Chapter 5.4 --- Summary --- p.65 / Chapter 6 --- DNA Sequencing by Hybridization (SBH) --- p.66 / Chapter 6.1 --- Problem Formulation: Reconstructing a DNA Sequence from Hybridization Data --- p.70 / Chapter 6.2 --- Proposed Memetic Optimization Algorithm --- p.71 / Chapter 6.2.1 --- Chromosome Encoding --- p.71 / Chapter 6.2.2 --- Fitness Function --- p.73 / Chapter 6.2.3 --- Crossover --- p.74 / Chapter 6.2.4 --- Hill Climbing Local Search for Sequencing by Hybridization --- p.76 / Chapter 6.2.5 --- Elitism and Diversity --- p.79 / Chapter 6.2.6 --- Outline of Algorithm: MA-HC-SBH --- p.81 / Chapter 6.3 --- Summary --- p.82 / Chapter 7 --- DNA Sequencing by Hybridization (SBH): Experiments and Results --- p.83 / Chapter 7.1 --- Experiment Settings --- p.83 / Chapter 7.2 --- Experiment Results --- p.85 / Chapter 7.3 --- Summary --- p.89 / Chapter 8 --- Conclusion --- p.90 / Chapter 8.1 --- Multiple Drugs Cancer Chemotherapy Schedule Optimization --- p.90 / Chapter 8.2 --- Use of the MA-IDP --- p.91 / Chapter 8.3 --- DNA Sequencing by Hybridization (SBH) --- p.92 / Chapter 8.4 --- Use of the MA-HC-SBH --- p.92 / Chapter 8.5 --- Future Work --- p.93 / Chapter 8.6 --- Item Learned --- p.93 / Chapter 8.7 --- Papers Published --- p.94 / Bibliography --- p.95
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Redução automática versus manual da pressão de suporte no desmame de pacientes em pós-operatório: estudo controlado e randomizado / Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomized controlled trialCorinne Taniguchi 29 September 2008 (has links)
INTRODUÇÃO: A redução automática da pressão de suporte (PS) baseada na freqüência respiratória, ou MRV (mandatory rate ventilation) é um modo ventilatório disponível no ventilador Taema-Horus. A hipótese do estudo é que o MRV utilizado no desmame é tão efetivo quanto o desmame manual em pacientes em pós-operatório na unidade de terapia intensiva (UTI). MÉTODOS: Ao chegar à UTI, após a cirurgia, os pacientes eram randomizados em dois grupos: desmame manual ou automático. O desmame manual consistiu na redução manual da PS a cada 30 minutos mantendo a relação freqüência respiratória sobre volume corrente menor do que 80, até a PS de 5-7 cmH2O. O desmame automático baseou-se na freqüência respiratória alvo de 15 respirações por minuto (o ventilador diminui automaticamente, a PS em 1 cmH2O a cada 4 ciclos respiratórios, se o paciente mantiver a freqüência respiratória abaixo deste valor). O objetivo primário do estudo foi comparar a duração do processo de desmame. Secundariamente verificamos o nível de PS, freqüência respiratória, volume corrente, índice de freqüência respiratória sobre volume corrente, pressão positiva expiratória final, fração inspirada de oxigênio e saturação de oxigênio requeridos durante o processo de desmame. Verificamos também necessidade de reintubação e necessidade de ventilação não invasiva nas primeiras 48 horas após a extubação. RESULTADOS: Não houve diferença estatística significativa entre os 53 pacientes selecionados em cada grupo quanto ao sexo (p=0541), idade (p=0,585) e tipo de cirurgia (p=0,172). Dezenove pacientes foram excluídos durante o protocolo (quatro no grupo manual e quinze no grupo automático, p<0,05). Nove pacientes do grupo automático foram excluídos do protocolo por não se adaptarem ao modo de desmame automático. Oitenta e sete pacientes concluíram o estudo, quarenta e nove pacientes foram desmamados manualmente e trinta e oito automaticamente. A duração do processo de desmame foi de 205,41±181,27 minutos (de 30 a 840 minutos) no grupo manual, e 157,33±129,98 minutos (de 30 a 545 minutos) no grupo automático. Não houve diferença estatística significante quanto ao tempo de desmame entre os dois grupos. O nível de PS foi maior (p<0,001) e freqüência respiratória foi menor (p=0,0098) no modo MRV comparado ao modo manual, durante o processo de desmame. Não houve necessidade de reintubação em nenhum dos grupos. Houve necessidade de ventilação não invasiva em dois pacientes do grupo manual (p=0,505), ambos sofreram cirurgia cardíaca. CONCLUSÃO: A redução automática da PS foi efetiva e pode ser utilizada no desmame de pacientes no pós-operatório na unidade de terapia intensiva, se o paciente se adaptar ao algoritmo do MRV / Introduction: Automatic pressure support reduction based on a target respiratory frequency or MRV is available in the TAEMA-HORUS ventilator for the weaning process in the ICU setting. We hypothesized that MRV is as effective as manual weaning in post-operative ICU patients. Methods: There were 106 patients selected, in the post-operative period in a prospective, randomized, controlled protocol. When the patients arrived in the ICU after surgery, they were randomly assigned to traditional weaning, consisted of the manual reduction of pressure support every thirty minutes, keeping the RR/TV(L) < 80 till 5-7 cmH20 of PSV. Alternatively, they were assigned to automatic weaning, referring to MRV set with a respiratory frequency target of 15 breaths per minute (the ventilator automatically decreased the PSV level by 1 cmH20 every 4 respiratory cycles, if the patients RR was less than 15 per minute). The primary endpoint of the study was the duration of the weaning process. Secondary endpoints were levels of pressure support, respiratory rate, tidal volume (mL), RR/VT (L), PEEP levels FiO2 and SpO2 required during the weaning process, the need for reintubation and the need for non-invasive ventilation in the 48 hours after extubation. Results: There were no statistically significant differences between the 53 patients selected for each group regarding gender (p=0.541), age (p=0.585) and type of surgery (p=0.172). Nineteen patients were excluded during the trial (4 in the PSV group and 15 in the MRV group, p<0.05). Eighty-seven patients concluded the study, forty-nine patients were weaned manually and thirtyeight automatically. The weaning duration process was 205.41 ± 181.27 minutes (30 to 840 minutes) for the manual group and 157. 33± 129.98 minutes (30 to 545 minutes) for MRV group (p=0.167). PSV levels were significantly higher and RR was lower in MRV compared to that of the PSV manual reduction (p<0.05). Reintubation was not required in either group. NIV was necessary for two patients, in the manual group after cardiac surgery (p=0.505). Conclusion: The automatic reduction of pressure support was effective and can be useful for weaning patients in the post-operative period in the ICU, if the patient is receptive to the MRV algorithm
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