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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
31

Estudo comparativo entre o controle robótico e humano da ótica na cirurgia videoassistida para simpatectomia torácica / A comparative study between robotic and human-assisted control of the optics in video-assisted thoracic sympathectomy

Joaquim Fernando Martins Rua 27 November 2007 (has links)
INTRODUÇÃO: Com o avanço da tecnologia, alguns equipamentos vêm sendo incorporados ao ato operatório, dentre eles os robôs, que apesar da notoriedade ainda são considerados controversos. MÉTODO: Trabalho clínico aleatorizado, duplo cego, avaliando a segurança e a eficiência, na cirurgia torácica videoassistida, para o tratamento da hiperidrose palmar/axilar, comparando o grupo \"Hu\" (auxiliar humano) e o grupo \"Ro\" (auxiliar robô), na manipulação da ótica. Foram analisados 38 casos, 19 casos em cada grupo, \"Hu\" e \"Ro\". Todos os procedimentos foram realizados sob anestesia geral, com secção do nervo simpático ao nível T3, T4 e G3. Os procedimentos foram filmados e gravados, sendo que dois observadores independentes avaliaram: número de movimentos inadvertidos, toques em estruturas da cavidade torácica e número de vezes em que a ótica foi retirada para limpeza. Foram avaliados, ainda, os seguintes parâmetros: 1. quanto à segurança - intercorrências cirúrgicas, dor torácica e aspecto da cicatriz; 2. quanto à eficácia - tempos total, cirúrgico e de utilização de ótica, presença de anidrose palmar/axilar, permanência hospitalar, hiperidrose vicariante e satisfação com o resultado do procedimento. RESULTADOS: Os resultados obtidos comparando o grupo \"Hu\" e \"Ro\", quanto à segurança, mostram que não houve diferença estatisticamente significativa nos seguintes parâmetros: intercorrências cirúrgicas, movimentos inadvertidos, dor torácica e aspecto da cicatriz entre os dois grupos. Porém, o número de toques em estruturas na cavidade torácica foi menor no grupo \"Ro\" (p<0,001). Quanto à eficácia, não ocorreu diferença estatisticamente significativa entre os dois grupos nos seguintes parâmetros: número de vezes em que a ótica foi retirada para limpeza, presença de anidrose palmar/axilar, permanência hospitalar, hiperidrose vicariante e grau de satisfação com o resultado do procedimento. Porém, o grupo \"Hu\" apresentou menor tempos total, de cirurgia e de utilização da ótica (p<0,001), quando comparado ao grupo \"Ro\". CONCLUSÕES: Podemos concluir que o auxílio da robótica no manuseio da ótica, na cirurgia videoassistida para realização de simpatectomia torácica para tratamento da hiperidrose, é seguro e eficiente, quando comparado ao auxílio humano. / INTRODUCTION: With the advance of technology, some pieces of equipment have been incorporated into the surgical act, among which robots, that, in spite of their notoriety, are still considered controversial. METHOD: A randomized double blind clinical study to evaluate the safety and efficiency in video-assisted thoracic surgery for the treatment of palmar/axillary hyperhidrosis, comparing the \"Hu\" (human-assisted) group and the \"Ro\" (robot-assisted) group, in the manipulation of the optics. Thirty-eight cases were analyzed, 19 cases in each group, \"Hu\" and \"Ro\". All the procedures were conducted under general anesthesia, with the ablation of the sympathetic nerve at T3, T4 and G3 levels. The procedures were recorded, in that two independent observers assessed: the number of involuntary movements, contact with structures of the thoracic cavity, and the number of times in which the optics was removed to be cleaned. The following parameters were also assessed: 1. on safety - surgical events, thoracic pain and scar appearance; 2. on efficiency - total times, surgical and optics use, presence of palmar/axillary anhydrosis, hospital stay, vicarious hyperhidrosis and satisfaction with the result of the procedure. RESULTS: The results obtained by comparing the \"Hu\" and \"Ro\" groups on safety show there was no significant statistical difference in the following parameters: surgical events, involuntary movements, thoracic pain and scar appearance between the two groups. However, the number of contacts with structures in the thoracic cavity was less in the \"Ro\" group (p<0.001). On efficiency, there was no significant statistical difference between the two groups in the following parameters: number of times in which the optics was removed to be cleaned, presence of palmar/axillary anhydrosis, hospital stay, vicarious hyperhidrosis, and the level of satisfaction with the result of the procedure. However, the \"Hu\" group presented less total time of surgery and of optics use (p<0.001), when compared to the \"Ro\" group. CONCLUSIONS: We can conclude that the robot-assisted procedure in handling the optics in video-assisted thoracic sympathectomy for the treatment of hyperhidrosis is safe and efficient when compared to the human-assisted procedure.
32

Thorakoskopische Untersuchungen am stehenden Rind

Dorn, Katja 10 December 2013 (has links)
Zielsetzung: In dieser Studie wurde an 15 gesunden Rindern die Methode der Thorakoskopie erprobt mit dem Ziel, eine Grundlage für den weiteren Einsatz dieses Verfahrens am bovinen Thorax zu schaffen. Im Mittelpunkt standen die Entwicklung einer geeigneten Untersuchungstechnik und die Beschreibung der endoskopisch dargestellten, im Pleuraspalt gelegenen Organe sowie möglicher pathologischer Befunde. Weiterhin galt es Komplikationen zu ermitteln und anhand der Erfahrungen aus diesem Versuch Indikationen für den Einsatz dieses minimal-invasiven Verfahrens beim Rind zu formulieren. Methodik: Alle Tiere wurden einer links- und rechtsseitigen Thorakoskopie jeweils mit und ohne intrapleurale Insufflation von Kohlenstoffdioxid über einen interkostalen Zugang unterzogen. Im Rahmen des Versuches fanden folglich vier Thorakoskopien je Rind und insgesamt 60 Thorakoskopien mit einer Wartezeit von 24 Stunden zwischen den einzelnen Untersuchungen statt. Die Untersuchungen erfolgten am im Zwangsstand fixierten, lokal anästhesierten Tier. Der endoskopische Zugang lag stets auf Höhe des Tuber coxae und variierte vom 8. bis zum 10. Interkostalraum. Nach interkostaler Schnittinzision wurde eine Zitzenkanüle bis in den Pleuraspalt vorgeschoben. Der spontane Einstrom von Raumluft in das Cavum pleurae führte zum Teilkollaps des ipsilateralen Lungenflügels. Die Kanüle wurde durch eine Trokar-Hülsen-Einheit ersetzt und die Hülse stellte nach Entfernung des Trokars den Zugang für die Optik. Je Hemithorax wurde die Untersuchungszeit auf 20 Minuten festgelegt. Sie begann im kranialen Pleuraspalt, wurde über (dorso)-kranial, (dorso)-medial, (dorso)-kaudal, ventrokaudal und ventral fortgeführt und endete mit ventrokranial ausgerichteter Optik. Ergebnisse: Die meisten im Cavum pleurae gelegenen Organe konnten ohne die Insufflation von CO2 ausreichend adspiziert werden. Während der links- und rechtsseitigen Thorakoskopien gelang die Adspektion großer Bereiche der Pleura costalis mit den Mm. intercostales interni sowie den Aa. et Vv. intercostales dorsales, Anteile der Lungenflügel und des Ligamentum pulmonale, der Aorta thoracica, des thorakalen Ösophagus, des M. longus colli, von Lymphknoten des Lc. thoracicum dorsale sowie der Lnn. mediastinales caudales, der Pars thoracica des Truncus sympathicus und des Truncus vagalis dorsalis des N. vagus. Des Weiteren konnten der M. psoas major, Anteile des Diaphragmas und der V. phrenica cranialis, der Hiatus aorticus, der Arcus lumbocostalis sowie unregelmäßig die A. et V. bronchoesophagea adspiziert werden. Die Untersuchung des rechten kranialen Pleuraspaltes war mit Einschränkungen behaftet und spiegelte sich in einer reduzierten Darstellung der sympathische Nervenfasern aus dem Ggl. cervicothoracicum, des Truncus costocervicalis dextra sowie der V. costocervicalis dextra wider. Linksseitig war die Betrachtung dieser Organe bzw. der korrespondierenden linksseitig angelegten Organe regelmäßig möglich. Weiterhin gelang während der linksseitigen Untersuchung die Adspektion des Ln. tracheobronchalis sinister, des Truncus brachiocephalicus sowie der V. azygos sinistra. Rechtsseitig konnte die V. azygos dextra stets adspiziert werden. Die Darstellung des Ductus thoracicus erfolgte nur bei einem der untersuchten Rinder infolge einer pathologischen Kompression. Während der Untersuchungen unter passivem Lungenkollaps war das Perikard nur bei einer rechtsseitigen Thorakoskopie zu sehen. Die Zweituntersuchungen des ipsilateralen Pleuraspaltes fanden während der Insufflation von CO2 bis zu einem Überdruck von 5 mm Hg statt. Dies sollte einen stärkeren Lungenkollaps bewirken und damit die Sicht auf intrapleural gelegene Organe verbessern. Während der Insufflation waren beidseits größere Anteile der Rippen und des Zwerchfells sowie das Perikard linksseitig bei drei Rindern und rechtsseitig bei einem Rind darstellbar. Postoperative Röntgenaufnahmen dienten dem Ausschluss des Vorhandenseins eines ipsi- oder kontralateralen Pneumothorax. Schlussfolgerung: Die Studie zeigt, dass Thorakoskopien an stehenden, gesunden Rindern sicher und komplikationsarm durchzuführen sind. Die beschriebene, minimal-invasive Technik stellt eine wertvolle, zusätzliche Methode zur tierschonenden Abklärung intrathorakaler Erkrankungen beim Rind dar. Der diagnostische, palliative oder therapeutische Nutzen muss in weiterführenden Untersuchungen ermittelt werden. / Objective: A study on 15 healthy cows was conducted to prove the thoracoscopic technique with the aim to establish a basis for further application of this procedure on cattle. Focus was on developing an adequate examination technique, displaying and describing of physical as well as pathological findings on intrathoracic organs examined endoscopically. Furthermore perioperative complications and indications of this minimally invasive method on cattle should be presented. Methods: The animals underwent a left and right side thoracoscopy under passive lung collapse and under insufflation of CO2. Therefore four thoracoscopies at each cow and a total of 60 thoracoscopies were performed with a waiting time of 24 hours between each examination. The cows were restrained in a stock and locally anesthetized. The endoscopic portal was lined up horizontally with the level of the ventral margin of the coxal tuber, at the point where the local anaesthetic had been injected and varied between the eighth and the tenth intercostal space. After a vertical stab incision through the skin and subcutaneous tissues a blunt stainless teat cannula was introduced into the pleural space. At this point air streamed spontaneously into the pleural space following by an ipsilateral lung collapse. The teat cannula was then removed and replaced by a sharp guarded trocar. After that the trocar was removed and the endoscope was passed through the remaining cannula. The time assessment for examination of each thorax was 20 minutes, started in the cranial pleural space, was continued in the (dorso)-cranial, (dorso)-medial, (dorso)-caudal, ventrocaudal und ventral direction and ended with ventrocranially aligned optic. Results: Most of the intrathoracic organs were seen without additional CO2 insufflation. During left and right side thoracoscopies large parts of the costal pleura, the internal intercostal muscles, the dorsal intercostal veins and arteries, parts of the lungs and the pulmonary ligament, the thoracic aorta, the thoracic part of the esophagus and the longus colli muscle, caudal mediastinal lymph nodes and lymph nodes associated with the dorsal thoracic lymph center, the thoracic part of the sympathic trunk and the dorsal vagus nerve were seen. Furthermore the psoas major muscle, parts of the diaphragm and the cranial phrenic vein, the aortic hiatus, the lumbocostal arch and intermittently the broncho-esophageal artery and vein could be identified. There were some constraints during right side thoracoscopy of the cranial pleural space which caused a limited view at the sympathic nerve fibres associated with the cervicothoracic ganglion, the right costocervical trunk and the right costocervical vein. At the left side these organs, the corresponding left side organs respectively, were constantly seen. Moreover during the exam at the left pleural space the left tracheobronchial lymph node, the brachiocephalic trunk and the left azygos could be well identified. During right side thoracoscopy the right azygos vein was always visible. In one case the presentation of the thoracic duct succeeded as a result of its pathological compression. During examination under passive lung collapse the pericard was visualized in one cow during right side thoracoscopy. The second thoracoscopies of the ipsilateral pleural space were conducted during insufflation of CO2 with a pressure of 5 mm Hg. A stronger lung collapse should result during insufflation with an enhanced view of the organs located intrapleurally. During insufflation at both sides larger parts of the ribs and diaphragm as well as the pericard on the left side at three cattle and on the right side at one cattle could be seen. Postoperative radiographies ensured the absence of an ipsi- or contralateral pneumothorax. Conclusion: This study shows that thoracoscopies on standing healthy cattle could be safely performed without major perioperative complications or side effects. The described minimally invasive procedure is a valuable, gentle and additional method to diagnose intrathoracic diseases in cattle. The use of thoracoscopy as diagnostic tool, for curative and palliative therapy should be identified in further studies.
33

Bilateralna torakoskopska simpatektomija kod osoba sa primarnom fokalnom hiperhidrozom / Bilateral thoracoscopic sympathectomy in patients with primary focal hyperhidrosis

Kuhajda Ivan 26 February 2016 (has links)
<p>Uvod: Primarna fokalna hiperhidroza (PFH) je poremećaj nepoznate etiologije koji se karakteri&scaron;e prekomernim znojenjem na predilekcionim mestima. Podjednako se javlja kod osoba mu&scaron;kog i ženskog pola tokom dvadesetih i početkom tridesetih godina života, pri čemu se smatra da je učestalos PFH oko 2,8% u ukupnoj populaciji. Nastaje kao posledica hiperaktivnosti simaptičkog nervnog sistema ka znojnim žlezdama. Karakteristično je za PFH da se ne javlja noću, &scaron;to sugeri&scaron;e da emocionalni stimulus igra bitnu ulogu u nastanku ovog poremećaja. Bilateralna torakoskopska simpatektomija (BTS) je minimalno invazivna hirur&scaron;ka procedura koja se danas primenjuje u trajnom lečenju PFH, sa niskom stopom komplikacija i omogućava lečenje kao jednodnevne hirur&scaron;ke procedure. Ciljevi ovog istraživanja su bili: a) da se ispita ukupna efikasnost BTS na trajno smanjenje PFH predilekcionih delova tela - dlanova, pazu&scaron;nih jama, lica i stopala; b) da se ispita efiksanost BTS kod osoba sa PFH u odnosu na različite nivoe transekcije simpatičkog lanca; c) da se ispita uticaj BTS na plućnu i srčanu funkciju kod operisanih osoba sa PFH; d) da se ispita pojava, trajanje i intenzitet kompenzatornog znojenja nakon BTS kod operisanih osoba sa PFH; e) da se ispita pojava, trajanje, lokalizacija i tretman postoperativnog bola nakon BTS kod osoba sa PFH; f) da se utvrde postoperativne komplikacije BTS kod osoba sa PFH; i g) da se ispita uticaj BTS na kvalitet života kod operisanih osoba sa PFH. Radna hipoteza istraživanja je bila da hirur&scaron;ka procedura - minimlano invazivna BTS ima značajan efekat na prekomerno znojenje na predilekcionim mestima kod osoba sa PFH, da je praćena sa minimalnim morbiditetom, bez kliničkog uticaja na plućnu i srčanu funkciju i da značajno pobolj&scaron;ava kvalitet života operisanih osoba. Materijal i metod: Urađena je prospektivna klinička studija koja je uključila 435 osoba sa PFH, koji su operisani bilateralnom torakoskopskom simpatektomijom, na Klinici za grudnu hirurgiju, Instituta za plućne bolesti Vojvodine u Sremskoj Kamenici između 2010 i 2014 godine. Kriterijumi za uključivanje u studiju bili su: a) da su osobe sa utvrđenom i procenjenom PFH pristale da učestvuju u istraživanju ispunjavajući preoperativno i postoperativno upitnike o efektima BTS i kvalitetu života nakon operacije; b) da nisu imali prethodne grudno hirur&scaron;ke intervencije, frakture rebara, masivne pneumonije ili empijem pleure; c) da nisu imali te&scaron;ki poremećaj plućne ili srčane funkcije; d) da ne boluju od sekundarne hiperhidroze. Primarna fokalna hiperhidroza je bila ustanovljena i procenjena anamnestičkim podacima, kliničkom slikom i pregledom koji je bio fokusiran na kvalitativno ispitivanje. Bilateralna torakoskopska simpatektomija izvođena je u op&scaron;toj anesteziji, a transekcija simpatičkog lanca je rađena pomoću ultrazvučno aktiviranog skalpela. Osobe sa izvedenom BTS zbog PFH bile su klasifikovane u tri grupe, u zavisnosti od nivoa transekcije simpatičkog lanca: a) transekcija na nivou drugog do četvrtog torakalnog gangliona (T2-T4); b) transekcija na nivou trećeg do četvrtog torakalnog gangliona (T3-T4); i c) transekcija na nivou drugog do trećeg torakalnog gangliona (T2-T3). Za procenu kompenzatornog znojenja i kvaliteta života kori&scaron;ćene je: Hyperhidrosis Disease Severity Scale (HDSS) za intenzitet kompenzatornog znojenja i kvaliteta života nakon BTS. Rezultati: Od 435 osoba sa PFH kod kojih je urađena BTS, bilo je 142 (32,64%) osobe mu&scaron;kog pola i 293 (67,36%) osoba ženskog pola, prosečne starosti od 29,68&plusmn;7,6 godina. Pozitivan nasledni faktor navelo je 167 osoba (38,62%). Najče&scaron;ća lokalizacija prekomernog znojenja kod osoba u ovom istraživanju je bila kombinacija dlanova, pazu&scaron;nih jama i tabana, koju je imalo 167 osoba (38,39%). Pre operacije, preko 60% ispitivanih osoba je navelo da im je kvalitet života lo&scaron; ili izuzetno lo&scaron;. Kod svih operisanih osoba u ovom istraživanju, operacija je izvedena uspe&scaron;no obostrano. Nije bilo smrtnih ishoda. Od intraoperativnih komplikacija zabeležena je jedna konverzija (0,23%) u minitorakotomiju zbog krvavljenja iz interkostalne vene. Neposredni postoperativni uspeh BTS kod operisanih osoba zbog PFH, a na osnovu prve kontrole posle nedelju dana bio je zabeležen kod svih (99,54%), osim kod dve osobe (0,46%) koje su imale postoperativne komplikacije: pareza n. ulnarisa i Hornerov sindrom kod jedne osobe i Horner sindrom kod druge osobe. Postoperativni morbiditet nakon BTS bio je zabeležen kod 32 osobe (7,35%). Izrazito pobolj&scaron;anje, odnosno značajno smanjenje znojenja kod osoba sa PFH zabeleženo je kod 428 operisanih (98,39%). Osobe sa transekcijom simpatičkog lanca na nivou gangliona T3-T4 imali su najbolji rezultat sa pobolj&scaron;anjem kvaliteta života u 85,03% operisanih. Kompenzatorno znojenje se nakon BTS javilo kod 316 (72,64%) operisanih osoba, a samo 2,53% je navelo da je postoperativno kompenzatorno znojenje izuzetno jakog intenziteta. Postoperativni bol bio je prisutan kod 79,77% operisanih osoba, sa prosečnim trajanjem do dve nedelje. Analgetike je postoperativno koristilo 24,21% anketiranih osoba. Od 287 operisanih osoba u ovom istraživanju, koji su pre operacije naveli da su imali i prekomerno znojenje tabana, nakon 6 meseci 185 osoba (64,46%) je navelo da se prekomerno znojenje tabana smanjilo. Iako postoji statistička značajnost u promeni vitalnog kapaciteta u smislu njegovog povećanja &scaron;est meseci nakon BTS (sa 4,49&plusmn;1,15 L na 4,54&plusmn;1,11 L), ta promena nije bila klinički relevantna. Promene u krvnom pritisku i srčanom pulsu, iako zabeležene, takođe nisu imale klinički značaj. Kvalitet života, pre BTS ocenjen kao lo&scaron; (i izuzetno lo&scaron;) bio je prisutan kod 265 osoba (60, 92%), a 6 meseci posle operacije ocenjen je kao odličan i dobar kod 428 osoba (98,39%). Zaključak: BTS kao minimalno invazivna hirur&scaron;ka procedura kod osoba sa PFH ima minimalni morbiditet, a visoku uspe&scaron;nost u smanjenju prekomernog znojenja na predilekcionim mestima, sa pobolj&scaron;anjem kvaliteta života kod 98,39% operisanih, sa minimalnim promenama plućne i srčane funkcije koje nisu klinički relevantne.</p> / <p>Primary focal hyperhidrosis (PFH) is a disorder of an unknown etiology, characterized by excessive sweating of predilective parts of the body. It affects men and women equally, with a peak incidence in the later second and early third decades of life, with incidence of up to 2,8% of the world population. It is caused by hyperactivity of the sympathetic nervous system to the sweat glands. It has been shown that PFH does not occur during the sleeping times, which suggests that emotional stimuli play an important role in this disorder. Bilateral thoracoscopic sympathectomy (BTS) is minimal invasive surgical procedure, which has evolved into an effective and permanent treatment for severe PFH, with low rate of morbidity and it can be performed as the one day surgical procedure. The aims of this investigation were: a) to examine the overall efficiency of BTS on permanent reduction of PFH of predilective parts of the body-palms, armpits, faces and soles; b) to examine the efficiency of BTS with different levels of transection among the persons with the PFH; c) to examine the influence of BTS on cardio-pulmonary function tests in persons with PFH after the operation; d) to examine the incidence, duration and intensity of compensatory sweating after BTS among persons with PFH; e) to examine the incidence, duration, localization and treatment of postoperative pain after BTS among persons with PFH; f) to determine postoperative complications of BTS among persons with PFH; g) to examine the influence of BTS on quality of life among persons with PFH. The working hypothesis of this investigation is that surgical procedure &ndash; minimal invasive BTS has the permanent effect on excessive sweating of predilective parts of the body among persons with PFH, followed by minimal morbidity, without clinical influence on cardio-pulmonary function and significantly improves the quality of life among persons with PFH. This was a prospective clinical study which included 435 patients with PFH, who have been operated with BTS, at the Clinic for Thoracic surgery, the Institute for pulmonary diseases of Vojvodina, Sremska Kamenica, between 2010 and 2014. The including criteria for the investigation were: a) persons with confirmed and estimated PFH accepted to participate in this investigation, fulfilling pre and postoperatively questionnaire about BTS effects and quality of life after the operation; b) absence of previous thoracic surgical procedures, rib fractures, massive pneumonias or pleural empyema; c) satisfactory cardio-respiratory function; d) absence of secondary hyperhidrosis. Primary focal hyperhidrosis was confirmed and estimated by anamnesis, clinical examination focused on qualitatively examination. Bilateral thoracoscopic sympathectomy was performed with general anesthesia, using harmonic scalpel for transection of sympathetic chain. Persons with PFH who underwent the BTS were classified into three groups, depending the level of transaction of sympathetic chain: a) transection at the level from the second to the forth thoracic sympathetic ganglion (T2-T4); b) transection at the level from the third to the forth thoracic sympathetic ganglion (T3-T4); c) transection at the level from the second to the third thoracic sympathetic ganglion (T2-T3). For the assessment of postoperative pain, compensatory sweating and quality of life next scales have been used: standardized numeric pain rating scale and Hyperhidrosis Disease Severity Scale (HDSS) for intensity of compensatory sweating and quality of life. Among 435 persons with PFH who underwent the BTS in this investigation, 142 (32,64%) were male and 293 (67,36%) female persons, with mean age of 29,68&plusmn;7,6. There was no mortality or serious intraoperative complications that required operative conversio from minimal invasive surgical procedure to thoracotomy. Among 435 persons with PFH who underwent the BTS in this investigation, 142 (32,64%) were male and 293 (67,36%) female persons, with mean age of 29,68&plusmn;7,6. Positive genetic factor has been found in 167 persons (38,62%). The most common localisation of excessive sweating in this investigation was the combination of palms, armpits and soles in 167 persons (38,39%). Before the operation, over 60% of persons estimated their quallity of life as bad or very bad. The operation was successfully performed in all patients bilaterally. There was no mortality in this investigation. There was one intraoperative complication, bleeding from intercostal vein, requiring conversion to minithoracotomy. Immediatelly postoperative success after BTS seven days after the operation was achieved in all persons accepted in two persons (0,46%) due to the postoperative complications: nervous ulnaris paresis and Horner syndrome in one person and Horener syndome in the other person. Postoperative morbidity after the BTS was recoreded in 32 persons (7,35%). Marked improvement, as significant reduction of sweating in persons with PFH was achieved in 428 operated persons (98,39%). Transection of sympathetic chain on level T3-T4 achieved improvement of quality of life in 85,03% operated persons with PFH. Compensatory sweating after the BTS has occurred in 316 (72,64%) operated persons, but only 2,53% operated persons declared compensatory sweating as severe. Postoperative pain was presented in 79,77% operated persons, with average duration of two weeks. Analgetics used only 24,21% of operated persons. There were 287 operated persons in this investigation, who claimed to have plantar hyperhidrosis before the operation and six months after the operation 185 persons (64,46%) claimed to have a reduction of plantar sweating. Although there was a clinical significance in changes of vital capacity after the BTS (from 4,49&plusmn;1,15 L to 4,54&plusmn;1,11 L), ther was no clinical significance. Changes in blood pressure and heart rate, although recoreded, had no clinical significance. Quality of life, before the BTS was recorded as bad or very bad in 265 persons (60,92%), and six months after the operation as excellent or good in 428 persons (98,39%) persons. Conclusion: In patients with PFH, BTS as minimal invasive surgical procedure, has a minimal morbidity and high success in treatment of excessive sweating, with improvemnet of quality of life in 98,39% operated person, with changes in cardio-pulmonary functions that are not clinical relevant.</p>

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