The purpose of this study was to determine the validity of the Ebbeling one-stage submaximal treadmill protocol to estimate maximal oxygen uptake in overweight males and females. Forty-five male and females (36.5±10.9 years; 170.2±9.9 cm; 77.9±9.0 kg) were categorized into overweight groups using a BMI of 25-29.9 kg/m2. The subjects performed a submaximal protocol that consisted of one 4-minute stage with individualized speeds of 2.0-4.5 mph at 5% grade and subsequently performed a maximal exercise test. There were significant relationships between observed and estimated VO2max for males (r=.796), females (r=.426), and gender combined (r=.844). There was an underestimation in the estimation of VO2max in the present study when comparing males (10%), females (26%) and gender combined (17%) subjects. The results indicated that a body mass index between the values of 25-29.9 kg/m2 did create a difference in estimating VO2max in the present study when comparing that to Ebbeling et al. (1991).Ball State UniversityMuncie, IN 47306 / School of Physical Education

Thesis (M.S.)--James Madison University, 2009. / Includes bibliographical references.

This study examined whether a high-intensity interval (IT) or a continuous steady-state (CT) exercise training program had the greatest effect on fat oxidation rates and fat mass loss in a population of untrained overweight and obese females. Thirteen female subjects (VO2peak 30.6 ± 1.29 ml.kg.min-1, BMI 29 ± 0.79, fat mass [FM] 33.3 ± 2.09 kg) were randomly assigned to either a CT (exercise at the relative intensity that elicits the maximal fat oxidation rate [FATmax] ) or an IT (intervals alternating 5 minutes at 40% and 85% VO2peak) training group that exercised approximately 1 hour, 3 days.week-1 for 10 weeks. Body composition assessments, peak oxygen uptake (VO2peak), FATmax and plasma free fatty acid (FFA) concentrations were examined pre- and post-training using dual-energy X-ray absorptiometry (DEXA), ParvoMedics gas analysis system and FFA half micro tests (Roche Diagnostics). No significant differences were found post-training in body weight (kg), body fat (%), fat-free mass, or fat mass (P>0.05). The relative exercise intensity that elicited FATmax was significantly increased from 35.3 ± 2.55% to 44.7 ± 3.56% in the IT group post-training (P <0.05). The maximal fat oxidation rate was determined at a higher relative exercise intensity after 10 weeks of a IT program compared with a CT program, which resulted in longer durations of fat oxidation during submaximal exercise bouts. These data suggest that an IT program induces a greater increase in the relative exercise intensity that elicits maximal fat oxidation after 10 weeks of training compared to a CT program in this population. Although body composition and FATmax were not altered, it is possible that through training induced metabolic adaptations from the IT program, intramuscular triacylglyceride (IMTG) contributions to fat oxidation at a given steady-state work rate could be increased post-training.

The heart rate achieved with maximal upper limb exercise is quoted as being on average thirteen beats per minute lower than when performing maximal leg exercise. Many canoeists use heart rate monitors during training and seek advice on setting their heart rate training zones. Existing guidelines are based on lower limb-derived heart rates, which may not be appropriate. As canoeists use predominantly their upper limbs during canoeing, it was hypothesized that as their upper limbs are trained, they may achieve heart rates and oxygen consumption similar to those achieved with lower limb exercise. The purpose of this investigation was to compare the relationship between heart rate and oxygen consumption when exercising on either a kayak ergometer or treadmill. Fifteen volunteer canoeists, who compete regularly, were recruited by convenience, purposive sampling and randomly allocated to a V02max test using open circuit spirometry, on either a kayak ergometer or treadmill. They returned within 5 to 7 days for a V02max test on the other apparatus. Their heart rates were also measured during these activities. The heart rate oxygen consumption relationship for upper and lower limb exercise was then analysed. Maximum heart rate was on average only 6 beats per minute lower with upper limb exercise, with some subjects achieving the same or very similar HRmax; the median difference in heart rate maximum was only 4 beats per minute. Although the response of heart rate and oxygen consumption to kayaking and running was similar at any given workload, the heart rate on the kayak was about 8 beats per minute higher at any submaximal workload. V02max. on the kayak was lower than on the treadmill. At any metabolic equivalent, the tidal volume was lower on the kayak and there was a lower respiratory rate on the treadmill. At any tidal volume, the metabolic equivalent was lower on the kayak ergometer. The minute volume on the kayak was higher than on the treadmill, for all but the highest intensities of exercise. Using the leg heart rate max to determine the training zones, a slightly higher (negligible) percentage of arm V0max is achieved at any given percentage heart rate. Kayakers who train regularly, appear to be able to attain similar maximum heart rates with upper and lower limb exercise, but a lower V02max when exercising with their arms. The heart rate oxygen consumption response is the same for upper and lower body exercise; and a reduced HRmax and increased heart rate at any sub maximal workload do not appear to apply to canoeists. It is therefore concluded that heart rate training zones based on leg HRmax are suitable for kayak training. This study has helped distinguish the difference between the heart rates of the upper and lower limbs at any given oxygen consumption in canoeists. The benefits of performing this study have also been to provide better advice to canoeists on how to train using heart rate monitors. / Thesis (M.Med.Sc.)-University of Natal, Durban, 2003.

Ground contact results in the generation of a heel-strike transient that propagates through the musculoskeletal system. The inability to attenuate the heel-strike-induced shock wave is a possible factor in the development of various gait pathologies and overuse-type injuries, such as knee osteoarthrosis, stress fractures, and low back pain. It is hypothesized that prolonged running will result in increased shock transmission at the tibia and sacroiliac joint during conditions of controlled velocity/stride mechanics. Subjects performed an extended running trial for 25-minutes at 75% HRReserve. EMG data of the vastus medialis, vastus lateralis, and tibialis anterior and accelerometer data from the tibial tuberosity and sacrum were recorded at one-minute intervals. Accelerometer data at the tibial tuberosity did show a significant increase during the run protocol. Linear regression of EMG frequency and tibial shock also demonstrated a significant relationship. An extended running protocol will lead to increases in tibia shock acceleration independent of stride mechanics. / School of Physical Education

Thesis (M.S.)--Michigan State University. Small Animal Clinical Sciences, 2008. / Title from PDF t.p. (viewed on July 27, 2009) Includes bibliographical references. Also issued in print.

Thesis (M.S.)--University of Wisconsin--La Crosse, 2002. / Includes bibliographical references.

Thesis (M.S.)--South Dakota State University, 2005. / Includes bibliographical references (leaves 68-72). Also available online (PDF file) by a subscription to the set or by purchasing the individual file.

Thesis (M.S.)--South Dakota State University, 2005. / Includes bibliographical references (leaves 68-72).

Ao longo dos últimos anos observou-se um aumento no número de idosos no mundo, com isso faz-se necessário buscar terapias que amenizem os danos relacionados e também elucidar os mecanismos envolvidos neste processo. O exercício físico tem sido sugerido como uma ferramenta importante, não farmacológica, para atenuar os déficits relacionados à idade. Ainda, estudos recentes sugerem uma relação entre o processo de envelhecimento cerebral e o desequilíbrio de mecanismos epigenéticos, contudo, estes dados ainda não são conclusivos. Sabe-se que o grau de neuroplasticidade varia com a idade e que as estruturas encefálicas podem responder diferentemente à exposição ao exercício. Estudos demonstram que o córtex pré-frontal está envolvido em funções de alta ordem como atenção, tomada de decisão e memória de trabalho. Portanto, o objetivo deste trabalho foi avaliar os efeitos de diferentes protocolos de exercício físico (sessão única e exercício diário moderado) sobre a modulação de marcadores epigenéticos em córtex pré-frontal de ratos Wistar de 3 e 21 meses de idade. Os animais foram submetidos ao protocolo de sessão única (20 minutos) ou o exercício diário moderado (20 minutos durante 14 dias), 1 hora após a última sessão foram eutanasiados. O córtex pré-frontal foi dissecado e a acetilação da H4, o conteúdo da DNA metiltransferase (DNMT1 e DNMT3b), assim como a atividade da histona metiltransferase H3K27 foram analisadas. Os resultados serão apresentados na versão completa desta dissertação. / Over the past few years the number of elderly people has increased in the world, therefore it is necessary to search therapies that ameliorate age-related deficits as well as elucidate the mechanisms involved in this process. Physical exercise has been suggested as an important non-pharmacological approach to alleviate the age-related decline. Furthermore, recent studies have suggested a relationship between the process of brain aging and imbalance of epigenetic mechanisms, however, these data are not conclusive. It is well described that prefrontal cortex is involved in higher functions like attention, decision making and working memory. Then, the aim of this study was to investigate the effects of two exercise protocols (single session and daily moderate exercise) on the modulation of epigenetic markers in the prefrontal cortex from Wistar rats of 3- and 21- months-old. Animals were submitted to single session protocol (20 minutes) or the daily moderate exercise (20 minutes for 14 days), and 1hour after the last exercise session animals were euthanized. Prefrontal cortex was dissected out and acetylation of H4, the content of DNA methyl transferase (DNMT1 and DNMT3B), as well as histone methyltransferase H3K27 activity were analyzed. Results will be presented in the full version.