Diss. (sammanfattning) Linköping : Linköpings universitet, 2008. / Härtill 5 uppsatser.

El objetivo del estudio fue determinar la prevalencia y evaluar el valor de la detección de Vaginosis Bacteriana entre las 22 - 24 semanas en la predicción de parto pretérmino espontáneo en gestaciones únicas. Se realizó un estudio observacional analítico de tipo cohorte en el Instituto Especializado Materno Perinatal durante enero a diciembre del 2002. Un total de 1218 gestantes cumplieron los criterios de inclusión (perdiéndose 18 al seguimiento); a quienes se tomó una muestra de secreción vaginal para tinción Gram interpretándose los resultados para Vaginosis Bacteriana según los criterios de Nugent. La incidencia de parto pretérmino fue 11,8% y la prevalencia de Vaginosis Bacteriana 37,2%. De las 1200 muestras, 475 tuvieron flora normal (39,6%), 279 flora intermedia (23,2%) y 446 (37,2%) Vaginosis Bacteriana. El antecedente de parto pretérmino, multiparidad y riesgo social alto se asociaron con parto pretérmino espontáneo. No hubo diferencia significativa entre Vaginosis Bacteriana y parto pretérmino < 37 semanas de gestación; observándose en los casos con flora normal, intermedia y Vaginosis Bacteriana, 40 (28,3%), 49 (34,8 %) y 52 (36,9%) partos pretérminos; respectivamente. El parto muy pretérmino (< 33 semanas) se asoció significativamente con el grado de la flora, presentándose 17 (12,1%), 27 (19,1%) y 52 (36,9%) partos muy pretérminos, en los casos con flora normal, intermedia y Vaginosis Bacteriana; respectivamente. Para parto pretérmino espontáneo la Vaginosis Bacteriana tuvo una sensibilidad de 12,8%, una especificidad de 95,3% un valor predictivo positivo de 35,3% y un valor predictivo negativo de 84,3%. Concluimos que la Vaginosis Bacteriana no es predictor de parto pretérmino espontáneo y no recomendamos su uso en la práctica clínica. Palabras Claves: Vaginosis Bacteriana, parto pretérmino espontáneo, predicción.

Determina los factores personales asociados a infecciones vaginales en gestantes que realizan su atención prenatal en el Centro Materno Infantil Ollantay de San Juan de Miraflores durante junio y julio del 2016. Es un estudio de tipo observacional, descriptivo, prospectivo y de corte transversal, en el cual participan 39 gestantes con diagnóstico de infección vaginal que realizaron su atención prenatal en el Centro Materno Infantil Ollantay de San Juan de Miraflores durante junio y julio del 2016. Utiliza un cuestionario estructurado en cuatro partes para reconocer las características personales de las gestantes con infecciones vaginales. Cada parte está conformada por preguntas de acuerdo a las dimensiones tomadas en cuenta: características sociodemográficas, antecedentes gineco-obstétricos, hábitos de higiene genital y conductas sexuales. Encuentra que los tipos de infecciones vaginales de las gestantes son: 51.3% presenta Candidiasis vaginal, el 38.5% presenta vaginosis bacteriana y el 10.2% presenta tricomoniasis. Concluye que los factores personales que están asociados a infecciones vaginales en gestantes son: inicio de vida sexual antes de los 19 años (89.7%), antecedentes de flujo vaginal con olor (74,4%) y acompañado de prurito vulvar (51.3%), no se lavan las manos con agua y jabón antes de orinar y defecar (71.8%), mantiene relaciones sexuales durante la gestación (89.7%) y sin preservativo (97.4%).

Thesis advisor: Caroline Bicks / In the last ten years, Eve Ensler’s The Vagina Monologues has morphed from a successful off-Broadway production into an activist movement that fosters fundraising productions of the play by community and campus groups in almost every country. In this thesis, I examine how the ‘body stories’ told by actual women made it to community stages all over the world through a series of translations: first, how Ensler poetically/theatrically interprets their stories; second, how the monologic form (and the current multiple-actor form) of the play affects the meaning of those stories; third, projecting how the audience reacts to those stories; and last, suggesting possibilities for broadening the audience’s experience into community discussion and social change. / Thesis (BA) — Boston College, 2010. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: English Honors Program. / Discipline: College Honors Program. / Discipline: English.

El objetivo del estudio fue determinar la prevalencia y evaluar el valor de la detección de Vaginosis Bacteriana entre las 22 - 24 semanas en la predicción de parto pretérmino espontáneo en gestaciones únicas. Se realizó un estudio observacional analítico de tipo cohorte en el Instituto Especializado Materno Perinatal durante enero a diciembre del 2002. Un total de 1218 gestantes cumplieron los criterios de inclusión (perdiéndose 18 al seguimiento); a quienes se tomó una muestra de secreción vaginal para tinción Gram interpretándose los resultados para Vaginosis Bacteriana según los criterios de Nugent. La incidencia de parto pretérmino fue 11,8% y la prevalencia de Vaginosis Bacteriana 37,2%. De las 1200 muestras, 475 tuvieron flora normal (39,6%), 279 flora intermedia (23,2%) y 446 (37,2%) Vaginosis Bacteriana. El antecedente de parto pretérmino, multiparidad y riesgo social alto se asociaron con parto pretérmino espontáneo. No hubo diferencia significativa entre Vaginosis Bacteriana y parto pretérmino < 37 semanas de gestación; observándose en los casos con flora normal, intermedia y Vaginosis Bacteriana, 40 (28,3%), 49 (34,8 %) y 52 (36,9%) partos pretérminos; respectivamente. El parto muy pretérmino (< 33 semanas) se asoció significativamente con el grado de la flora, presentándose 17 (12,1%), 27 (19,1%) y 52 (36,9%) partos muy pretérminos, en los casos con flora normal, intermedia y Vaginosis Bacteriana; respectivamente. Para parto pretérmino espontáneo la Vaginosis Bacteriana tuvo una sensibilidad de 12,8%, una especificidad de 95,3% un valor predictivo positivo de 35,3% y un valor predictivo negativo de 84,3%. Concluimos que la Vaginosis Bacteriana no es predictor de parto pretérmino espontáneo y no recomendamos su uso en la práctica clínica. Palabras Claves: Vaginosis Bacteriana, parto pretérmino espontáneo, predicción.

The vagina is one organ of the body which has not been studied exhaustively. Moreover, most of the studies found in the contemporary literature have been performed on women affected by a variety of genital diseases. In the present study the vaginal epithelium was examined with a histological method, morphometry, whereby cyclical changes related to hormonal variation during the menstrual cycle were demonstrated. Determination of the quantity of estrogen receptors in the vaginal epithelium on two occasions during the menstrual cycle revealed a significantly greater number in the follicular than in the luteal phase. The results of these studies indicate the presence of a menstrual variation in the vaginal epithelium comparable to that in the endometrium. Phenoxymethylpenicillin (pcV) was used as a marker substance to study the dynamics of the transport mechanisms into the vagina. PcV was found to accumulate in the vaginal fluid and high concentrations persisted for a long period of time. In hysterectomized women, the appearance of pcV in the vaginal fluid followed the same pattern. Consequently, the substance is transported through the vaginal wall and need not enter with the secretions from the internal genitalia. The greatest concentration of pcV was in the distal portion of the vagina, possibly due to the specific internal circulation of fluid within the vagina. Bacterial vaginosis as an example of an ‘ecological disease’ has been studied with regard to the formation of endotoxin, a constituent of the cell wall of Gram- negative bacteria. Large amounts of endotoxin were found and the clinical implication of this finding has been pointed out. Furthermore, the influence of pcV on the vaginal microbial flora of healthy women has been investigated. A change from a situation with predominance of lactobacilli to the appearance of Gram-negative rods was observed. In one of the women the lactobacilli disappeared completely and were replaced by E. coliand high levels of endotoxin in the vaginal fluid were found. This study demonstrates the complexity of the ecological balance of the vaginal microbial flora and illustrates the difficulty of defining a ‘normal’ vaginal condition. Is there any unquestionable state of ‘normality’ even in a healthy woman free from symptoms of genital disease? / <p>S. 1-22: sammanfattning, s. 25-64: 6 uppsatser</p> / digitalisering@umu

Thesis (Ph.D. Biotechnology)--University of Waikato, 2006. / Title from PDF cover (viewed April 8, 2008) Includes bibliographical references (p. 222-234)

Thesis (Ph. D.)--Vrije Universiteit te Amsterdam, 1996.

Thesis (Ph. D.)--Vrije Universiteit te Amsterdam, 1996.

Made available in DSpace on 2014-06-11T19:26:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-12-07Bitstream added on 2014-06-13T20:54:35Z : No. of bitstreams: 1 delmanto_a_me_botfm_prot.pdf: 1594635 bytes, checksum: 59b8850497a3a71e0f5ae2ec36c4ccb0 (MD5) / Fundação para o Desenvolvimento Médico e Hospitalar (Famesp) / Analisar o efeito do raloxifeno sobre o epitélio vaginal de mulheres pós-menopausa. Métodos: Estudaram-se prospectivamente entre novembro de 2004 a fevereiro de 2006, 80 mulheres na pós-menopausa. Quarenta pacientes receberam 6Omg/dia de raloxifeno (GR) e 40 mulheres compuseram o grupo não tratado (grupo controle, GC), pareado por idade e tempo de menopausa. O grupo tratado foi composto por pacientes com osteoporose de coluna lombar e/ou colo do fêmur. Foram excluídos aquelas com sinais e/ou sintomas de infecção do trato genital inferior e usuárias de terapia hormonal (TH) até seis meses prévios ao estudo. Os esfregaços vaginais foram coletados em dois momentos: inicial (MO) e após seis meses de seguimento (Ml). Para avaliação do epitélio vaginal foi utilizado o valor de maturação, com a contagem de células superficias, intermediárias e parabasais. Os esfregaços foram analisados por único citopatologista, sem conhecimento dos dados das pacientes. Para análise estatística empregou- se o teste t de Student, teste Wilcoxon Mann-Witney e o teste Qui-Quadrado. Resultados: Na comparação estatística inicial os grupos foram homogêneos. Comparando os momentos inicial e final, não foram observadas diferenças estatisticamente sígnífícativas nos valores medianos de maturação do epitélio vaginal e na porcentagem de células superficiais, intermediárias e parabasais entre os grupos. Não foi constatada correlação linear significativa entre o valor de maturação e a idade, o tempo de menopausa, o uso ou não de TH prévia, tabagismo e o índice de massa corpórea, em ambos os grupos. Conclusão: O tratamento com raloxifeno por seis meses não alterou o valor de maturação do epitélio vaginal em mulheres na pós-menopausa. / To analyze the effect of raloxifene on the vaginal epithelium of postmenopausal women. Methods: Eighty postmenopausal women were studied prospectively between November of 2004 and February of 2006. Forty patients received 6omglday of raloxifene (GR), and 40 women comprised the non-treated group (control group, CG), paired by age and time of menopause. The treated group was composed of patients with osteoporosis of the lumbar column and / or femur. Those with signs and / or symptoms of infection of the inferior genital tract and users of hormonal therapies (HT) up to six months prior to the study were excluded. Vaginal smears were collected at two moments: initial (MO) and after six months of follow-up (Ml). To evaluate the vaginal epithelium, the maturation value was determined, along with counts of superficial, intermediate and parabasal cells. Smears were analyzed by only one cytopathologist, without knowledge of patient data. For statistical analysis Student's t test, Wilcoxon Mann Witney test and Chi-Squared test were employed. Results: In the initial statistical comparison the groups were homogeneous. Comparing the initial and final moments, no statistically significant differences were observed in median values of vaginal epithelial maturation or in percentage of superficial, intermediate and parabasal cells between the groups. There was no significant linear correlation between value of vaginal epithelial maturation and age, time of menopause, use or not of previous HT, smoking or body mass index, in both groups. Conclusion: Treatment with raloxifene for six months did not alter the maturation value of vaginal epithelium in postmenopausal women.