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One important topic in medical image analysis is segmenting wall structures from different cardiac medical imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI). This task is typically done by radiologists either manually or semi-automatically, which is a very time-consuming process. To reduce the laborious human efforts, automatic methods have become popular in this research. In this thesis, features insensitive to data variations are explored to segment the ventricles from CT images and extract the left atrium from MR images. As applications, the segmentation results are used to facilitate cardiac disease analysis. Specifically, 1. An automatic method is proposed to extract the ventricles from CT images by integrating surface decomposition with contour evolution techniques. In particular, the ventricles are first identified on a surface extracted from patient-specific image data. Then, the contour evolution is employed to refine the identified ventricles. The proposed method is robust to variations of ventricle shapes, volume coverages, and image quality. 2. A variational region-growing method is proposed to segment the left atrium from MR images. Because of the localized property of this formulation, the proposed method is insensitive to data variabilities that are hard to handle by globalized methods. 3. In applications, a geometrical computational framework is proposed to estimate the myocardial mass at risk caused by stenoses. In addition, the segmentation of the left atrium is used to identify scars for MR images of post-ablation.

This thesis chronicles my experiences with developing a panelized wall system for use by Habitat for Humanity and with testing that system in the design and construction of a house. Presented as a series of narratives, it follows the progress of the project from August 2003 to December 2005. Described is my motivation to test my theories through design and construction, the applicability of prefabrication to Habitat for Humanity’s use of unskilled volunteer labour, the incorporation of panelization into the design of a house for the Waterloo Region affiliate of Habitat for Humanity, the prefabrication of preclad wood framed wall panels for this house by students at the University of Waterloo School of Architecture, the erection of these wall panels on-site, and the completion of the house to a weathertight state. The thesis concludes with discussions of the understanding I gained through my experiences, the necessity for further development and testing of the panelized wall system, and the future use of prefabrication by Habitat for Humanity.

Turbulent gas-solid flows are readily encountered in many industrial and environmental processes. The development of a generic modeling technique for gas-solid turbulent flows remains a significant challenge in the field of mechanical engineering. Eulerian models are typically used to model large systems of particles. In this dissertation, a numerical analysis was carried out to assess a current state-of-the-art Eulerian two-fluid model for fully-developed turbulent gas-solid upward flow in a vertical pipe. The two-fluid formulation of Bolio et al. (1995) was adopted for the current study and the drag force was considered as the dominant interfacial force between the solids and fluid phase. In the first part of the thesis, a two-equation low Reynolds number k-ε model was used to predict the fluctuating velocities of the gas-phase which uses an eddy viscosity model. The stresses developed in the solids-phase were modeled using kinetic theory and the concept of granular temperature was used for the prediction of the solids velocity fluctuation. The fluctuating drag, i.e., turbulence modulation term in the transport equation of the turbulence kinetic energy and granular temperature was used to capture the effect of the presence of the dispersed solid particles on the gas-phase turbulence. The current study documents the performance of two popular turbulence modulation models of Crowe (2000) and Rao et al. (2011). Both models were capable of predicting the mean velocities of both the phases which were generally in good agreement with the experimental data. However, the phenomena that small particles cause turbulence suppression and large particles cause turbulence enhancement was better captured by the model of Rao et al. (2011); conversely, the model of Crowe (2000) produced turbulence enhancement in all cases. Rao et al. (2011) used a modified wake model originally proposed by Lun (2000) which is activated when the particle Reynolds number reaches 150. This enables the overall model to produce turbulence suppression and augmentation that follows the experimental trend. The granular temperature predictions of both models show good agreement with the limited experimental data of Jones (2001). The model of Rao et al. (2011) was also able to capture the effect of gas-phase turbulence on the solids velocity fluctuation for three-way coupled systems. However, the prediction of the solids volume fraction which depends on the value of the granular temperature shows noticeable deviations with the experimental data of Sheen et al. (1993) in the near-wall region. Both turbulence modulation models predict a flat profile for the solids volume fraction whereas the measurements of Sheen et al. (1993) show a significant decrease near the wall and even a particle-free region for flows with large particles. The two-fluid model typically uses a low Reynolds number k-ε model to capture the near-wall behavior of a turbulent gas-solid flow. An alternative near-wall turbulence model, i.e., the two-layer model of Durbin et al. (2001) was also implemented and its performance was assessed. The two-layer model is especially attractive because of its ability to include the effect of surface roughness. The current study compares the predictions of the two-layer model for both clear gas and gas-solid flows to the results of a conventional low Reynolds number model. The effects of surface roughness on the turbulence kinetic energy and granular temperature were also documented for gas-particle flows in both smooth and rough pipes.

MRI is a well known and widely spread technique to characterize cardiac pathologies due to its high spatial resolution, its accessibility and its adjustable contrast among soft tissues. In attempt to close the gap between blood flow, myocardial movement and the cardiac fucntion, researching in the MRI field addresses the quantification of some of the most relevant blood and myocardial parameters. During this proyect a new tool that allows reading, postprocessing, quantifying and visualizing 2D motion sense MR data has been developed. In order to analyze intracardiac blood flow and wall motion, the new tool quantifies velocity, turbulent kinetic energy, pressure and strain. In the results section the final tool is presented, describing the visualization modes, which represent the quantified parameters both individually and combined; and detailing auxiliary tool features as masking, thresholding, zooming, and cursors. Finally, thecnical aspects as the convenience of two dimensional examinations to create compact tools, and the challenges of masking as part of the relative pressure calculation, among others, are discussed; ending up with the proposal of some future developments.

Vår uppsats kommer beröra Zombies på film och fokusera på filmen Land of the Dead. Många människor upplever zombies som inget mer än monster, en fara för karaktärerna att klara sig undan. Vi vill uppmärksamma att all populärkultur i varierande utsträckning gestaltar verklighet, och analysera hur Zombies används för att gestalta aspekter av vårt samhälle.

This thesis chronicles my experiences with developing a panelized wall system for use by Habitat for Humanity and with testing that system in the design and construction of a house. Presented as a series of narratives, it follows the progress of the project from August 2003 to December 2005. Described is my motivation to test my theories through design and construction, the applicability of prefabrication to Habitat for Humanity’s use of unskilled volunteer labour, the incorporation of panelization into the design of a house for the Waterloo Region affiliate of Habitat for Humanity, the prefabrication of preclad wood framed wall panels for this house by students at the University of Waterloo School of Architecture, the erection of these wall panels on-site, and the completion of the house to a weathertight state. The thesis concludes with discussions of the understanding I gained through my experiences, the necessity for further development and testing of the panelized wall system, and the future use of prefabrication by Habitat for Humanity.

Wood is a highly versatile renewable material (with carbon sequestering properties), that is light in weight, has good strength properties in both tension and compression while providing good rigidity and toughness, and good insulating properties (relative to typical structural materials). Engineered wood products combine the benefits of wood with engineering knowledge to create optimized structural elements. Cross-laminated timber (CLT), as one such engineered wood product, is an emerging engineering material which provides great opportunities for the building industry. While building with wood has many benefits, there are also some concerns, particularly decay. Should wood be exposed to elevated amounts of moisture, rots and moulds may damage the product or even risk the health of the occupants. As CLT panels are a relatively new engineered wood product, the moisture characteristics have yet to be properly assessed. Consequently, the amount of decay risk for CLT in building applications is unknown, and recommended protective actions during design construction and operation have yet to be determined. The goal of this research was to determine the moisture durability of CLT panels in wall assemblies and address concerns related to built-in construction moisture. The approach used to address the problem was to first determine select moisture properties of CLT panels through experimental approaches, and then use the results to calibrate a hygrothermal model to quantify the risks of wall assemblies. The wall assemblies were simulated in six different cities across Canada, representing a range of climates: Vancouver, B.C., Edmonton, A.B., Winnipeg, M.B., Ottawa, O.N., Québec City, Q.C., and St. John, New-Brunswick. The risks associated with moisture exposure during construction are also considered in the simulations. The experimental phase of the research was limited to moisture uptake tests. These tests were utilized to determine the liquid water absorption coefficient for four different types of full scale panels (2’x2’) and 12 clear wood samples. The panels were either made of 5-ply of Western-SPF, Eastern-SPF, Hemlock-Fir, or 3-ply of a generic softwood provided by a European CLT manufacturer; the clear samples were all cut from the same nominal 2x6 SPF-grade lumber. The panels were installed in a drying rack and gravimetrically tracked to assess the drying rates of the panels. Finite resources precluded more thorough material testing, but a parametric study was conducted to determine the relative impact of the missing material data on the final simulation results. In the hygrothermal simulations, four main wall assembly types were considered- those with either exterior or interior insulation, and those using either vapour permeable or impermeable air-water barriers. Various types of insulation and vapour control were also modelled. The simulations were run for a variety of interior relative humidities. The metric for comparison between the simulations was the water content of a 4mm thin layer on the extreme lamina of a CLT panel system. The results of the simulation suggest that vapour impermeable membranes, when install on dry CLT panels (less than 14% M.C.) do not pose moisture risks in any of the climates considered. However, when high levels of construction moisture is considered, only vapour permeable membranes controlled moisture risks by allowing the CLT panel to dry both to the interior and to the exterior.

This thesis describes an investigation of the velocity field in a fluid around a solid sphere undergoing transient motion parallel to, and midway between, two plane walls. Particle Image Velocimetry (PIV) was used to measure the velocity at many discrete locations in a plane that was perpendicular to the walls and included the centre of the sphere. The transient motion was achieved by releasing the sphere from rest and allowing it to accelerate to terminal velocity. <p>To avoid complex wake structures, the terminal Reynolds number was kept below 200. Using solutions of glycerol and water, two different fluids were tested. The first fluid was 100%wt glycerol, giving a terminal Reynolds number of 0.6 which represents creeping flow. The second solution was 80%wt glycerol yielding a terminal Reynolds number of 72. For each of these fluids, three wall spacings were examined giving wall spacing to sphere diameter ratios of h/d = 1.2, 1.5 and 6.0. Velocity field measurements were obtained at five locations along the transient in each case. Using Y to denote the distance the sphere has fallen from rest, velocity fields were obtained at Y/d = 0.105, 0.262, 0.524, 1.05, and 3.15. <p>It was observed that the proximity of the walls tends to retard the motion of the sphere. A simple empirical correlation was fit to the observed sphere velocities in each case. A wall correction factor was used on the quasi-steady drag term in order to make the predicted unbounded terminal velocity match the observed terminal velocity when the walls had an effect. While it has been previously established that the velocity of a sphere is retarded by the proximity of walls, the current research examined the link between the motion of the sphere and the dynamics of the fluid that surrounds it. By examining the velocity profile between the surface of the sphere at the equator and the wall, it was noticed that the shear stresses acting on the sphere increase throughout the transient, and also increase as the wall spacing decreases. This is due to the walls blocking the diffusion of vorticity away from the sphere as it accelerates leading to higher shear stresses. <p>In an unbounded fluid, the falling sphere will drag fluid along with it, and further from the sphere, fluid will move upward to compensate. It was found that there is a critical wall spacing that will completely prevent this recirculation in the gap between the sphere and the wall. In the 80%wt glycerol case, this critical wall spacing is between h/d = 1.2 and 1.5, and in the 100%wt glycerol case the critical wall spacing is between h/d = 1.5 and 6.0.

The risk of food insecurity in the form of higher food prices has prompted policymakers in the United States (US) and European Union (EU) to revise their approach to biofuel development. The US Renewable Fuel Standard (RFS) and EU Directive 2009/28/EC require long term use of renewable energy in transportation, subject to sustainability. This thesis examines the implications of the US RFS and EU Directive 2009/28/EC in a trade context using a partial equilibrium/comparative static framework. The focus is on the effect of the revised biofuels policies on opportunities for developing countries to supply the US and/or EU markets. For the US, the implications when the volume produced and/or required under the RFS is technologically infeasible with imports of ethanol as a potential policy alternative are explored. For the EU, the impact of the sustainability criteria on foreign biodiesel suppliers in terms of compliance cost is examined. In general, the US policy may enhance opportunities for trade while the EU policy will likely inhibit trade. A discussion of the implications of the mandates for developing countries and WTO is included.