University, Diss., 2005--Bremen. / Erscheinungsjahr an der Haupttitelstelle: 2004.

Universiẗat, Diss., 2004--Bremen.

Universiẗat, Diss., 2005--Stuttgart.

Universiẗat, Diss., 2005--Tübingen.

This thesis is focused on the analysis of fetal ECG records measured by indirect method from mother´s abdomen. The thesis consists of the theoretical part is focused on fetal, heart development and description of fetal ECG signal. This thesis also offers an overview of fECG signal processing methods used nowadays. The practical part of the thesis deals with the implementation of algorithms based on wavelet transformation and Least Mean Square LMS method in Matlab programming environment. The final part of the thesis consists of the analysis of achieved results.

In this thesis, the red hot topic anomaly detection is studied, which is a subtopic in machine learning. The company, Procera Networks, supports several broadband companies with IT-solutions and would like to detected errors in these systems automatically. This thesis investigates and devises methods and algorithms for detecting interesting events in diagnostics data. Events of interest include: short-term deviations (a deviating point), long-term deviations (a distinct trend) and other unexpected deviations. Three models are analyzed, namely Linear Predictive Coding, Sparse Linear Prediction and Wavelet Transformation. The final outcome is determined by the gap to certain thresholds. These thresholds are customized to fit the model as well as possible. / I den här rapporten kommer det glödheta området anomalidetektering studeras, vilket tillhör ämnet Machine Learning. Företaget där arbetet utfördes på heter Procera Networks och jobbar med IT-lösningar inom bredband till andra företag. Procera önskar att kunna upptäcka fel hos kunderna i dessa system automatiskt. I det här projektet kommer olika metoder för att hitta intressanta företeelser i datatraffiken att genomföras och forskas kring. De mest intressanta företeelserna är framfärallt snabba avvikelser (avvikande punkt) och färändringar äver tid (trender) men också andra oväntade mänster. Tre modeller har analyserats, nämligen Linear Predictive Coding, Sparse Linear Prediction och Wavelet Transform. Det slutgiltiga resultatet från modellerna är grundat på en speciell träskel som är skapad fär att ge ett så bra resultat som mäjligt till den undersäkta modellen..

Over the last 20 years, much work has focused on computer-aided clinical decision support systems due to a rapid increase in the need for management and processing of medical knowledge. Among all fields of medicine, trauma care has the highest need for proper information management due to the high prevalence of complex, life-threatening injuries. In particular, hemorrhage, which is encountered in most traumatic injuries, is a dominant factor in determining survival in both civilian and military settings. This complication can be better managed using a more in-depth analysis of patient information. Trauma physicians must make precise and rapid decisions, while considering a large number of patient variables and dealing with stressful environments. The ability of a computer-aided decision making system to rapidly analyze a patient’s condition can enable physicians to make more accurate decisions and thereby significantly improve the quality of care provided to patients. The first part of this study is focused on classification of highly complex databases using a hierarchical method which combines two complementary techniques: logistic regression and machine learning. This method, hereafter referred to as Classification Using Significant Features (CUSF), includes a statistical process to select the most significant variables from the correlated database. Then a machine learning algorithm is used to identify the data into classes using only the significant variables. As the main application addressed by CUSF, a set of computer-assisted rule-based trauma decision making system are designed. Computer aided decision-making system not only provides vital assistance for physicians in making fast and accurate decisions, proposed decisions are supported by transparent reasoning, but also can confirm a physicians’ current knowledge, enabling them to detect complex patterns and information which may reveal new knowledge not easily visible to the human eyes. The second part of this study proposes an algorithm based on a set of novel wavelet features to analyze physiological signals, such as Electrocardiograms (ECGs) that can provide invaluable information typically invisible to human eyes. These wavelet-based method, hereafter referred to as Signal Analysis Based on Wavelet-Extracted Features (SABWEF), extracts information that can be used to detect and analyze complex patterns that other methods such as Fourier cannot deal with. For instance, SABWEF can evaluate the severity of hemorrhagic shock (HS) from ECG, while the traditional technique of applying power spectrum density (PSD) and fractal dimension (FD) cannot distinguish between the ECG patterns of patients with HS (i.e. blood loss), and those of subjects undergoing physical activity. In this study, as the main application of SABWEF, ECG is analyzed to distinguish between HS and physical activity, and show that SABWEF can be used in both civilian and military settings to detect HS and its extent. This is the first reported use of an ECG analysis method to classify blood volume loss. SABWEF has the capability to rapidly determine the degree of volume loss from hemorrhage, providing the chance for more rapid remote triage and decision making.

Obstructive sleep apnea is a potentially life-threatening condition characterized by repetitive episodes of upper airway obstruction that occur during sleep, usually associated with a reduction in blood oxygen saturation. In US population, 9% of women, 24% of men, and 2% of children have been diagnosed with obstructive sleep apnea, suggesting that 18 million people may suffer from the consequences of nightly episodes of apnea. One of the most significant symptoms of obstructive sleep apnea is profound and repeated hypoxia. The analysis of the interaction between cardiovascular and respiratory signals has been a widely-explored area of research due to the significance of the results in describing a functional relationship between the underlying physiologic systems; however, statistical and analytical approaches to analyze the changes in these signals before and after hypoxia are still in their early stages of evolution. A major motivation for this research has been the lack of methodologies to detect mean and/or variance shifts and identify root sources of variation in time-frequency characteristics of multichannel data. The contributions of this thesis are twofold. First, multiscale energy distributions based on wavelet transformations of the analyzed physiological signs are analyzed. This is followed by the development of an online multichannel monitoring approach based on principal curves that detects changes in the wavelet coefficients extracted from the analyzed signals.

The rise in digital technology has also rose the use of digital images. The digital imagesrequire much storage space. The compression techniques are used to compress the dataso that it takes up less storage space. In this regard wavelets play important role. Inthis thesis, we studied the Haar wavelet system, which is a complete orthonormal systemin L2(R): This system consists of the functions j the father wavelet, and y the motherwavelet. The Haar wavelet transformation is an example of multiresolution analysis. Ourpurpose is to use the Haar wavelet basis to compress an image data. The method ofaveraging and differencing is used to construct the Haar wavelet basis. We have shownthat averaging and differencing method is an application of Haar wavelet transform. Afterdiscussing the compression by using Haar wavelet transform we used another method tocompress that is based on singular value decomposition. We used mathematical softwareMATLAB to compress the image data by using Haar wavelet transformation, and singularvalue decomposition.

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