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Background: Poor demand for vaccines has long been recognized as a threat to the realization of public and global health objectives. Consequently, over time a range of interventions have been researched, proposed, and implemented in an attempt to improve the acceptability of vaccines and overcome vaccine resistance. However, much of the contemporary research concentrates disproportionately on individual-level determinants as viable targets for interventions. This disparate focus on individual-level factors has seemingly been at the expense of research into fundamental contextual influences. As a result, the primary aim of this thesis is to explore and develop a greater understanding of the contextual determinants of vaccine acceptability and their evolution over time and across different global contexts. Furthermore, emerging themes will be analyzed in an effort to explore how different contextual determinants work together or separately to influence vaccine acceptability. Methodology: The methodological approach adopted for this thesis concentrated on enabling and conducting an in-depth literature review of the contextual determinants of vaccine acceptability. To begin, a concept analysis was conducted to inform the design, focus, and implementation of a literature review. Subsequently, an in-depth literature review of research derived from the Global Health database was conducted using relevant papers published between 1910 and 2022. Data related to publication and content characteristics were extracted to support the analysis process and discussion. Ultimately themes related to the seven contextual determinants categories were identified, extracted, and analyzed. Results: Through the final analysis, 32, often interrelated themes were identified across the seven contextual determinant categories. The determinant category of Politics & Policy was found to be relevant in 70.5% (n=98) of articles included in this literature review. Religious, Social & Cultural determinants were relevant in 53.24% (n=74) of articles, followed by Communication & Media Environment at 43.16% (n=60), Influential Leaders at 41.37% (n=58), History & Historical Factors at 38.13% (n=53), Pharmaceutical Influences at 24.46% (n=34), and Geographic Influences at 18.7% (n=26). Conclusion: The acceptability of vaccines is undoubtedly influenced by the broader factors that shape the contexts in which vaccines are delivered. Additionally, these contextual determinants are likely to interact with, or influence the many commonly referenced putative individual-level determinants of vaccine acceptability. As a result, the complex nature of any relevant contextual determinants should be considered in the design of efforts aimed at promoting or improving demand for vaccines. / Thesis / Master of Science (MSc) / The contextual determinants of vaccine acceptability have been seemingly under- researched relative to other individual-level factors. As a result, this thesis aims to explore and develop a greater understanding of the contextual determinants of vaccine acceptability and their evolution over time and across different global contexts. To achieve this objective, an in-depth literature review of 139 identified articles was conducted in an effort to explore and identify themes related to the contextual determinant of vaccine acceptability. Ultimately, through this review 32 themes across the seven contextual determinant categories were identified and discussed. These findings helped elucidate the complex and fundamental role that contextual determinants have in shaping demand for vaccines.

acase@tulane.edu / Although the theoretical basis supporting the use of trauma-informed approaches in schools is promising, evidence for mechanisms of facilitating their acceptability among teachers is limited. Findings from implementation science indicate that foundational professional development training during pre-implementation activities can generate teacher support for a new approach, which is essential to successful formal implementation. Theoretical models point toward enhanced teacher knowledge of the approach as a predictor of such support. The current study examined whether foundational professional development training increased teacher knowledge of a new school-wide initiative, trauma-informed approaches, and evaluated that knowledge growth as a predictor of teacher perceptions of acceptability for trauma-informed approaches. Feasibility and system fit, two domains of perceived social validity of trauma-informed approaches, were assessed as potential moderators of the association between knowledge growth and acceptability. Although the training significantly increased teachers’ knowledge of trauma-informed approaches, knowledge growth did not predict acceptability ratings. Feasibility and knowledge growth did not interact to predict acceptability ratings. However, individuals providing higher ratings of system fit demonstrated a positive relationship between knowledge growth and acceptability. When system fit ratings were lower, knowledge growth predicted lower acceptability ratings. Findings provide partial support for foundational professional development training as a pre-implementation tool and identify factors that influence pre-implementation acceptability of trauma-informed approaches among teachers. / 1 / Elizabeth McIntyre

In 1959 Abbott Laboratories estimated (3) that every year 60 million persons go on controlled diets. Of these about 34 million have serious obesity problems, 3 million are diabetics and the rest have disorders that demand strict dietary measures.

People likely hold different opinions about deceptive communication. Lie acceptability refers to an individual's attitude about deceptive communication. A self-report measure of lie acceptability was updated and refined, and preliminary data (N = 312) consistent with validity were reported. CFA indicated acceptable fit to the a priori unidimensional model. As anticipated, the lie acceptability scale was positively related to narcissism and negatively associated with religiosity. The scale also predicted likelihood of use ratings of equivocal messages, deceptive omissions, and outright lies. An anticipated sex difference, however, was not replicated. The potential utility of the scale in communication research is discussed.

The purpose of the current study was to examine levels of treatment acceptability associated with three frequently implemented interventions (medication, token economy with response cost, and time-out) for children with characteristics of Attention-Deficit/Hyperactivity Disorder (ADHD). An additional purpose was to investigate the influence that the professional affiliation or label (i.e., special education teacher, school psychologist, and pediatrician) of the consultant making a treatment recommendation may have on the acceptability of a proposed treatment for a child displaying characteristics of ADHD. The participants consisted of 63 members of school assistance teams recruited from southwestern school districts. Participants read a case description of a child displaying characteristics of ADHD and a treatment vignette which manipulated the type of treatment recommended and the occupational title of the consultant making the treatment recommendation. Participants then rated the acceptability of the treatments using the Abbreviated Acceptability Rating Profile. Repeated measures ANOVA revealed significant differences in treatment acceptability ratings, with medication receiving less acceptable ratings than the other treatments and that the medication treatment was considered less acceptable when recommend by a special education teacher than when recommended by either a school psychologist or a pediatrician. A statistically significant interaction was identified between the consultant recommending the treatment and the type of treatment. This study investigated whether the consultant making a treatment recommendation impacted the level to which the treatment was accepted. This is unique in that the influence of the consultant making a treatment recommendation has not previously been studied in the literature on treatment acceptability. This finding may be useful when considering the frequency in which consultants from different occupations make recommendations. Recommendations for future research in treatment acceptability are discussed.

The suicide rate in the United States continues to rise, and rates of Veteran deaths are 1.5 times greater than those of non-Veteran adults. Previous research demonstrates that higher rates of suicide acceptability are positively related to suicide planning, suicidal ideation, and attempts. Examining rates of suicide acceptability in a Veteran and non-Veteran sample may be one pathway to understand the process by which attitudes are linked to behaviors. Study 1: Study 1 included a preliminary examination of a pre-screening measure, the Veteran Verification Questionnaire (VVQ), which aims to increase the validity of a Veteran sample online and reduce possible misrepresentation. Results indicated that the VVQ successfully differentiated between Veterans and non-Veteran students. Additionally, participants that answered 8 out of 12 possible items correctly were more likely to be Veterans (89%) whereas a score of 7 or less indicated that the participant was more likely to be a student. Study 2: Study 2 first examined whether or not veterans and non-Veterans differed significantly on suicide acceptability when accounting for age and sex. Study 2 also examined whether Veteran status predicted suicide acceptability using the Attitudes Towards Suicide Scale in the sample after accounting for age, sex, suicide risk and exposure to suicide. The results demonstrated that suicide acceptability rates varied significantly between Veterans and non-Veterans such that Veterans endorsed higher rates of suicide acceptability. The results from a hierarchical multiple regression analysis indicate that suicide risk, suicide exposure, and Veteran status accounted for a total of 25% of the variance in acceptability scores. The findings also demonstrate that Veteran status only accounted for 4% of the total variance whereas suicide risk accounted for 10% and exposure to suicide behaviors accounted for 11%. Interestingly, the direction of these predictions between suicide risk and exposure to suicide with suicide attitudes were opposite of expected.

BACKGROUND: Cervical cancer is a global disease with a disproportionate burden among low- and middle-income countries. In Tanzania, cervical cancer is the most common female cancer and a prophylactic vaccine offering protection against four human papillomavirus (HPV) strains is a promising prevention method. The targeted age and sex, as well as the sexually transmitted nature and novelty of the vaccine, support the need for formative research on the knowledge, attitudes, and barriers toward vaccination. OBJECTIVES: The first objective of this thesis was to systematically review studies of HPV vaccine acceptability among African countries. The second and third objectives were to describe and determine the socio-demographic factors and HPV-related knowledge and attitudes associated with HPV vaccination and to identify the barriers to vaccination among a population-based sample of rural and urban women in the Kilimanjaro Region of Tanzania. METHODS: The literature was systematically reviewed by searching electronic databases, and a data abstraction form structured by the Health Belief Model was used to collect data and synthesize findings. For objectives 2 and 3, a cross-sectional study was conducted among rural (n=303) and urban (n=272) women aged 18-55. Differences in socio-demographic factors, knowledge, attitudes, and barriers were compared between groups, and multivariable models were used to identify associations among rural and urban women separately. RESULTS: Reviewed literature suggested that HPV vaccine-related knowledge was low, however predicted acceptance of the vaccine was high. Research on this topic was largely composed of cross-sectional studies in urban areas. Among rural women in the Kilimanjaro Region, independent associations with acceptance included variables related to cost, knowledge, access, and educational attainment. Among urban women, independent associations were related to social networks/norms and educational attainment. The most frequent perceived barriers to vaccination were cost, side effects, and safety. CONCLUSION: Educational programs on the HPV vaccine and cervical cancer are needed in Tanzania and in other areas of Africa. This research suggests that vaccine campaigns in the Kilimanjaro Region should focus on emphasizing financial and physical accessibility, peer acceptance, and safety, in addition to highlighting endorsement of the vaccine by healthcare providers and the government. / Thesis (Master, Community Health & Epidemiology) -- Queen's University, 2013-10-15 21:01:17.426

Introduction Nearly all flat panel video display monitors have luminance and colour variations as the angle of view varies from the monitor’s perpendicular. The new MicrotileTM displays developed by Christie Digital are no exception to this general finding. A review of any book on colour science will show that there is substantial amount of literature on just noticeable colour differences within various colour spaces. Despite the wealth of data on the topic, there is no general consensus across different industries as to which colour space and colour difference equations are appropriate. Several factors like the background colour, object size, texture of the stimulus are different for different studies; these factors make it very difficult to determine precisely the effect of viewing angle on the perception of coloured images on the Microtiles display based on previous research. Hence, the objective of this thesis was to quantify the measured colour shifts of a Microtile display at different viewing angles, in steps of perceptible thresholds and to evaluate the acceptability of distortions at different viewing angles for complex scenes. Methods A preliminary experiment was setup to study the behaviour of Microtile display primaries as a function of viewing angle. The aim was to measure the shift in hue and luminance of the three primaries at different eccentricities (from 0o to 40o). The measured trend was used to simulate Microtile shifts on complex images for the rating task. In the first part of the perceptibility experiment, three reference colours were picked and 12 vectors heading towards the blue-yellow region of the L*a*b* colour space (pertaining to the colour shifts noticed with the Microtile displays). A uniform reference colour was presented in three of the four quadrants on the CRT monitor and one quadrant changed colour in the direction of the sampled vector. An adaptive, four alternate forced choice procedure was employed to determine thresholds for each of the 3 reference colours. The adaptive technique used was a ZEST paradigm. In the second part of the perceptibility experiment, eighteen directions were sampled around each reference colour. The rating task was based on simulating the measured attenuations of the Microtile primaries on complex scenes. Subjects rated the images both in terms of acceptability/unacceptability and as percentage image degradation. The simulation was presented on three static complex images, car, landscape and portrait. A total of 60 subjects participated in the study, 20 subjects for each experiment. All subjects were between the age group of 15 to 35 years of age and underwent battery of colour vision tests before being included in the study. All subjects included had average to superior colour discrimination as categorized using the FM-100 Hue discrimination test. Results Study1: The preliminary study on Microtile display characteristics as a function of viewing angle showed that all the three primaries decreased in luminance with change in viewing angle. The red primary decreased at a faster rate compared to the other two primaries. The trend presents as a decrease in luminance with the hue shifting towards the blue-green region of the CIE1974 L*a*b* space. Study 2: Results from both the first and second parts of the perceptibility experiment showed that the vectors sampled in different directions approximated to ellipsoids in the L*a*b* colour space. This finding was consistent with the colour discrimination literature. Vectors on the equi-luminance plane were significantly longer than the vectors on the non equi-Luminance plane. Results showed that the average perceptibility thresholds in the non equi-luminance direction were lower than 1∆ELab¬¬¬¬. Study 3: Results from the rating experiments showed that irrespective of the complexities in the images, distortions greater than five times thresholds were less than 50% acceptable and were rated to be at least 30% degraded. This corresponds to a viewing angle greater than 10o for a Microtile display. The relationship between the stimulus (ΔE) and subjective Image degradation judgements followed a linear relationship, with the portrait and landscape having similar functions, whereas the car was rated more degraded at lower ΔEs and less degraded at higher ΔEs compared with the other two scenes. Conclusion Perceptibility thresholds for different reference colours showed that the conventionally used calibration precision of 1 ΔELab is a lenient criterion. Perceptibility thresholds are at least 25% less for the Microtile display reference condition. From the results of the rating data a distortion greater than five times thresholds is less than 50% acceptable and appears to be at least 30% degraded for static complex images. However, the image quality judgments appear to be related to scene context, which requires further study.