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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 61 to 70 of 940 (0.076 seconds)Spelling suggestions: "subject:"anda immune response"" "subject:"ando immune response""
| 61 |
Development of a vaccine against the human hookworm, Necator americanusGirod, Nadine January 2001 (has links)
No description available.
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| 62 |
Signals, steroids and sparrows : testing the immunocompetence handicap hypothesisNorris, Sasha January 1998 (has links)
No description available.
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| 63 |
Local and systemic induction of an abundant CD4+CD25+ regulatory T cell population in non-Hodgkin's lymphomaMittal, Sajjan January 2009 (has links)
To investigate their importance in non-Hodgkin’s lymphoma (NHL), I enumerated Treg cells in peripheral blood mononuclear cells (PBMC) and involved tissues from 30 newly diagnosed patients CD25+FoxP3+CD127<sup>low</sup>CD4+ Treg cells were increased markedly in PBMC (median=20.4% CD4 T cells, n=20) versus healthy controls (median=3.2%, n=13:<i> p</i><0.001, rank sum test) and correlated with serum lactate dehydrogenase (n=14; R<sub>s</sub>=0.79, <i>p</i><0.001) and disease stage. I documented poor proliferation of T cells with mitogen ConA and almost none with recall antigens PPD and DPT in both PBMC and involved tissue samples (n=9). T cell hyporesponsiveness was reversed by depleting CD25+ cells (n=4), or by adding anti-CDLA-4 (n=3), supporting the view that Treg cells explain the systemic immunosuppression seen in NHL. As a high percentage of Treg cells were also present in involved tissues (patients’ involved tissues median=38.8% of CD4 T cells (n=15) vs. reactive nodes median=11.6% of CD4 T cells (n=2); <i>p</i>=0.02, rank sum test), I determined if tumour cells could induce a T regulatory phenotype. I incubated CD25+ depleted PBMC with tumour cells <i>in vitro</i> for five days. A dose and time dependent T regulatory phenotype induction from CD25+ depleted PBMC fractions were seen (n=6, maximum induction of 86.7%). Partial induction was seen when these fractions were separated with transwells. These ‘induced Treg cells’ were FACS sorted and suppressed effector T cells proliferation. I conclude that NHL cells are powerful inducers of Treg cells. These cells circulate systemically and induce active immune tolerance both systematically and within tumour microenvironment, thus representing a new therapeutic target in NHL.
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| 64 |
The human immune response to the latex allergen Hev b 5Sutherland, Michael F. (Michael Fraser), 1967- January 2003 (has links)
Abstract not available
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| 65 |
The human immune response to the latex allergen Hev b 5Sutherland, Michael F. (Michael Fraser), 1967- January 2003 (has links)
For thesis abstract select View Thesis Title, Contents and Abstract
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| 66 |
Regulation of bovine herpesvirus 1 (BHV-1) productive infection by viral genes (BICP0 or the LR gene), and cellular transcription factors (P300 or C/EBP-alpha)Geiser, Vicki Marie. January 1900 (has links)
Thesis (Ph.D.)--University of Nebraska-Lincoln, 2006. / Title from title screen (site viewed on Feb. 6, 2007). PDF text: vi, 218 p. : ill. UMI publication number: AAT 3218217. Includes bibliographical references. Also available in microfilm and microfiche format.
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| 67 |
Characterization of the feed intake and acute-phase protein responses of pigs following an acute immune challenge with lipopolysaccarideFrank, Jason W., January 2003 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2003. / Typescript. Vita. Includes bibliographical references (leaves 94-101). Also available on the Internet.
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| 68 |
Characterization of the feed intake and acute-phase protein responses of pigs following an acute immune challenge with lipopolysaccaride /Frank, Jason W., January 2003 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2003. / Typescript. Vita. Includes bibliographical references (leaves 94-101). Also available on the Internet.
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| 69 |
Isolation and characterisation of immunoglobulin A-alpha-1-antitrypsin complexes : role in the pathophysiology of chronic diseasesScott, Louise Jane January 1998 (has links)
No description available.
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| 70 |
Role of double-stranded RNA-binding protein PACT in MDA5-mediated antiviral innate immune responseLui, Pak-yin, 呂柏賢 January 2014 (has links)
abstract / Biochemistry / Doctoral / Doctor of Philosophy
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