In recent years, with advances in medical treatment, the demand of medical beauty market has increased year by year. With the continuous innovation of nanotechnology, medical technology with nanometer level is becoming the one of the most important issue of the development of medical biotechnology in recent years. In order to make the products effective, the products have to be transported into the human skin. In traditional medical treatments, the devices of contacting type or invading type were adopted, and might cause some infected problems. To avoid these situations, some medical companies have developing the non-contact type device¡Ð gene gun. This device use nitrogen as motive force to atomize the thin film of the injection products, then delivering these products to derma. This research utilizes computational fluid dynamics software to build the FEM simulation model of Venturi tube inside of a gene gun. Then, analyzing the speed and atomization of fluid which inside or outside of Venturi tube. A FEM simulated mechanism for the atomization of multiphase flow was constructed in this research successfully. The effects of variations of some geometric parameters of Venturi tube on the atomization of thin film were studied also. The obtained results can shorten cost and time in relevant development.

Understanding the physics governing primary atomization of high pressure fuel sprays is of paramount importance to accurately model combustion in direct injection engines. The small length and time scales of features that characterize this process falls below the resolution power of typical grids in CFD simulations, which necessitates the inclusion of physical models (sub-models) to account for unresolved physics. Unfortunately current physical models for fuel spray atomization used in engine CFD simulations are based on significant empirical scaling because there is a lack of experimental data to understand the governing physics. The most widely employed atomization sub-model used in current CFD simulations assumes the spray atomization process to be dominated by aerodynamically-driven surface instabilities, but there has been no quantitative experimental validation of this theory to date. The lack of experimental validation is due to the high spatial and temporal resolutions required to simultaneously to image these instabilities, which is difficult to achieve. The present work entails the development of a diagnostic technique to obtain high spatial and temporal resolution images of jet breakup and atomization in the near nozzle region of Gasoline Direct Injection (GDI) sprays. It focuses on the optical setup required to achieve maximum illumination, image contrast, sharp feature detection, and temporal tracking of interface instabilities for long-range microscopic imaging with a high-speed camera. The resolution and performance of the imaging system is characterized by evaluating its modulation transfer function (MTF). The setup enabled imaging of GDI sprays for the entire duration of an injection event (several milliseconds) at significantly improved spatial and temporal resolutions compared to historical spray atomization imaging data. The images show that low to moderate injection pressure sprays can be visualized with a high level of detail and also enable the tracking of features across frames within the field of view (FOV)

Mist or aerosol explosions present a serious hazard to process industries. Heat transfer fluids are widely used in the chemical process industry, are flammable above their flash points, and can cause aerosol explosions. Though the possibility of aerosol explosions has been widely documented, knowledge about their explosive potential is limited. Studying the formation of such aerosols by emulating leaks in process equipment will help define a source term for aerosol dispersions and aid in characterizing their explosion hazards. Analysis of the problem of aerosol explosions reveals three major steps: source term calculations, dispersion modeling, and explosion analysis. The explosion analysis, consisting of ignition and combustion, is largely affected by the droplet size distribution of the dispersed aerosol. The droplet size distribution of the dispersed aerosol is a function of the droplet size distribution of the aerosol formed from the leak. Existing methods of dealing with the problem of aerosol explosions are limited to enhancing the dispersion to prevent flammable concentrations and use of explosion suppression mechanisms. Insufficient data and theory on the flammability limits of aerosols renders such method speculative at best. Preventing the formation of aerosol upon leaking will provide an inherently safer solution to the problem. The research involves the non-intrusive measurement of heat transfer fluid aerosol sprays using a Malvern Diffraction Particle Analyzer. The aerosol is generated by plain orifice atomization to simulate the formation and dispersion of heat transfer fluid aerosols through leaks in process equipment. Predictive correlations relating aerosol droplet sizes to bulk liquid pressures, temperatures, thermal and fluid properties, leak sizes, and ambient conditions are presented. These correlations will be used to predict the conditions under which leaks will result in the formation of aerosols and will ultimately help in estimating the explosion hazards of heat transfer fluid aerosols. Heat transfer fluid selection can be based on liquids that are less likely to form aerosols. Design criteria also can incorporate the data to arrive at operating conditions that are less likely to produce aerosols. The goal is to provide information that will reduce the hazards of aerosol explosions thereby improving safety in process industries.

This study analyzes the sustainability of various energy sources including micro hydro power and biodiesel in the context of Nepal. The main focus is on the development of biodiesel fuels from non-edible oil resources including waste cooking oil, jatropha and soapnut oil feedstocks grown on the marginal lands of Nepal. Biodiesel fuel samples were prepared by acid and/or base catalyst transesterification. Both single stage and dual stage transesterification processes were employed depending on the free fatty acid content of the oil feedstock. The oil to biodiesel conversion rate and total yield were monitored. The quality of the biodiesel fuels including viscosity etc was confirmed by an external laboratory and all fuels met the ASTM fuel quality requirements. Canola, jatropha and soapnut biodiesel fuels were tested to determine some atomization properties - density, surface tension and viscosity - at elevated temperatures and pressures. The density of three biodiesel fuels and diesel were determined up to 523 K and 7 MPa using a capacitance type densitometer. The results showed a linear relationship with temperature and pressure over the measured range. The experimental data were well within the range of canola and other biodiesel fuels found in the literature. Kay’s mixing rule was used to predict the density of some biodiesel blends and the results were found to be in agreement with less than 5% error with the measured data. The surface tension was measured using a pendant drop apparatus for all three biodiesel and diesel fuels for temperatures and pressures up to 473K and 7 MPa. Results showed a linear relationship with temperature as well as with pressure. Temperature has a higher effect on surface tension than pressure. The viscosity of all three biodiesel and diesel fuels were measured using a torsional vibration viscometer up to 523 K and 7 MPa. Results showed that the viscosity-temperature relationship of all three biodiesel fuels tested followed a modified Andrade equation which was also applicable when temperature and pressure were both applied simultaneously. The measured and regressed kinematic and dynamic viscosities obtained were comparable with values in the literature. / This thesis is focused on sustainability analysis of alternative fuels in Nepal and presents the resullts of the tests on fuel and atomization characterisation of different biodiesel feedstocks including canola, jatropha, soapnut and waste cooking oil. A new model to evaluate sustainability of renewable alternatives energy resources has been developed and tested.

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The normal injection of a liquid jet into a gaseous crossflow has many engineering applications. In this thesis, detailed numerical simulations based on the level set method are employed to understand the physical mechanism underlying the jet ``surface breakup''. The numerical observations reveal the existence of hydrodynamic instabilities on the jet periphery. The temporal growth of such azimuthal instabilities leads to the formation of interface corrugations, which are eventually sheared off of the jet surface as sheet-like structures. The sheets finally undergo disintegration into ligaments and drops during the surface breakup process. Temporal linear stability analyses are employed to understand the nature of these instabilities. To facilitate the analysis, analytical solutions for the flow fields of the jet and the crossflow are derived. We identify the ``shear instability'' as the primary destabilization mechanism in the flow. This inherently inviscid mechanism opposes the previously suggested mechanism of surface breakup (known as ``boundary layer stripping''), which is based on a viscous interpretation. The influence of the jet-to-crossflow density ratio on the flow stability are also studied. The findings show that a higher density jet leads to higher wavenumber instabilities on the jet surface and thereby subsequent smaller drops and ligaments. The stability characteristics of the most amplified modes (i.e., the wavenumber and corresponding growth rate) obtained from stability analyses and numerical simulations are in good agreement. The stability results of the jet also show that the density may have a non-monotonic stabilizing/destabilizing effect on the flow stability. To investigate such effect, the concept of wave resonance are employed to physically interpret the inviscid instability mechanism in two-phase flows with sharp interfaces and linear velocity profiles. We demonstrate that neutrally stable waves are formed due to the density jump in the flow, in addition to the well-known vorticity (Rayleigh) waves. Under certain conditions, such neutral waves are capable of resonating and generating unstable modes. The resonance of different pairs of neutral waves, therefore, results in either stabilizing or destabilizing effect of density variation. We predict similar reasoning behind the density behavior in the jet in crossflow configuration with smoothly varying velocity and density profiles.

The objective of this thesis was to develop a novel understanding of the mechanics of two phase gas-liquid flows and sprays injected through industrial effervescent nozzles. This was done using detailed experimental investigations and scaling for two-phase flows and sprays. This study helps to quantify near-field liquid and gas phase statistics that are challenging and impossible to measure in the reactors due to inaccessibility restrictions. The development of nozzles is generally performed on air-water systems. My plan was to begin with the study of small-scale sprays (air and water) to compare to full scale industrial conditions at pilot operation (air-water) or at commercial operation (steam-bitumen), to determine size scaling relationships. The relationship between the lab scale air-water experiments and real industrial scale steam-bitumen has never been fully examined. Knowledge from this thesis will make the development of future nozzles with much less dependent on trial and error. This thesis was an attempt to establish fundamental scaling relationships for the prediction of two-phase spray behavior that can be applied directly to full scale industrial size nozzles that would be of very significant value to industries and to the scientific community in general. Understanding the performance of two phase nozzles through established scaling laws will aid in optimizing the two phase nozzle flow conditions and will serve as a major tool in nozzle design and development for future generation nozzles for many industrial applications.

Effervescent atomization has been a topic of considerable investigation in the literature due to its important advantages over other atomization mechanisms. This work contributes to the development of both effervescent atomizers and also laser-based techniques for spray investigation In order to develop non-intrusive measurement techniques for spray applications, a procedure is suggested to characterize the shape of droplets using image-based droplet analyzers. Image discretization which is a major source of error in droplet shape measurement is evaluated using a simulation. The accuracy of StereoPIV system in conducting droplet velocity measurement in a spray field is also investigated. To assist in the design of effervescent atomizers, bubble formation during gas injection from a micro-tube into liquid cross-flow is investigated using a Shadow-PIV/PTV system. The generated spray fields of two effervescent atomizers which operate using a porous and a typical multi-hole air injector are compared using qualitative images and Shadow-PTV measurement.

19 Dec 2004. / Published through the Information Bridge: DOE Scientific and Technical Information. "IS-T 2447" Amber Lynn Genau. 12/19/2004. Report is also available in paper and microfiche from NTIS.