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Application of squarate ester cascade reactions to the synthesis of (+/-) hypnophilin. New photorearrangements of 2-cyclopentenones. Studies towards the total synthesis of pectenotoxin IILiu, Jian 22 November 2002 (has links)
No description available.
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Enzyme cascade reactions on 3D DNA scaffold with dynamic shape transformation / 動的形状変換を伴う3D DNA足場での酵素カスケード反応LIN, PENG 26 July 2021 (has links)
京都大学 / 新制・課程博士 / 博士(エネルギー科学) / 甲第23437号 / エネ博第424号 / 新制||エネ||81(附属図書館) / 京都大学大学院エネルギー科学研究科エネルギー基礎科学専攻 / (主査)教授 森井 孝, 教授 佐川 尚, 教授 片平 正人 / 学位規則第4条第1項該当 / Doctor of Energy Science / Kyoto University / DFAM
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3D Face Reconstruction From Front And Profile ImageDasgupta, Sankarshan 09 August 2021 (has links)
No description available.
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Development of Direct Electron Transfer-Type Cascade System by Alcohol and Aldehyde Dehydrogenases / アルコール/アルデヒド脱水素酵素による直接電子移動型カスケード反応系の開発Adachi, Taiki 23 March 2023 (has links)
京都大学 / 新制・課程博士 / 博士(農学) / 甲第24664号 / 農博第2547号 / 新制||農||1098(附属図書館) / 学位論文||R5||N5445(農学部図書室) / 京都大学大学院農学研究科応用生命科学専攻 / (主査)教授 白井 理, 教授 菅瀬 謙治, 教授 三芳 秀人 / 学位規則第4条第1項該当 / Doctor of Agricultural Science / Kyoto University / DGAM
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Numerical Investigation of Subsonic Axial-Flow Tandem Airfoils for a Core Compressor RotorMcGlumphy, Jonathan 18 February 2008 (has links)
The tandem airfoil has potential to do more work as a compressor blade than a single airfoil without incurring significantly higher losses. Although tandem blades are sometimes employed as stators, they have not been used in any known commercial rotors. The goal of this work is to evaluate the aerodynamic feasibility of using a tandem rotor in the rear stages of a core compressor. As such, the results are constrained to shock-free, fully turbulent flow. The work is divided into 2-D and 3-D simulations. The 3-D results are subject to an additional constraint: thick endwall boundary layers at the inlet.
Existing literature data on tandem airfoils in 2-D rectilinear cascades have been compiled and presented in a Lieblein loss versus loading correlation. Large scatter in the data gave motivation to conduct an extensive 2-D CFD study evaluating the overall performance as a function of the relative positions of the forward and aft airfoils. CFD results were consistent with trends in the open literature, both of which indicate that a properly designed tandem airfoil can outperform a comparable single airfoil on- and off-design. The general agreement of the CFD and literature data serves as a validation for the computational approach.
A high hub-to-tip ratio 3-D blade geometry was developed based upon the best-case tandem airfoil configuration from the 2-D study. The 3-D tandem rotor was simulated in isolation in order to scrutinize the fluid mechanisms of the rotor, which had not previously been well documented. A geometrically similar single blade rotor was also simulated under the same conditions for a baseline comparison. The tandem rotor was found to outperform its single blade counterpart by attaining a higher work coefficient, polytropic efficiency and numerical stall margin. An examination of the tandem rotor fluid mechanics revealed that the forward blade acts in a similar manner to a conventional rotor. The aft blade is strongly dependent upon the flow it receives from the forward blade, and tends to be more three-dimensional and non-uniform than the forward blade. / Ph. D.
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Unsteady Turbulence Interaction in a Tip Leakage Flow Downstream of a Simulated Axial Compressor RotorMa, Ruolong 22 July 2003 (has links)
The unsteady behavior of a tip leakage flow downstream of a simulated axial compressor rotor has been studied. The Virginia Tech low speed linear cascade wind tunnel was adapted to model the unsteady tip leakage flow produced by a rotor operating in the vortical wakes of a set of stator vanes. The cascade, consisting of 8 GE rotor B blades, has adjustable tip gap, inlet angle of 65.1 degrees, turning angle of 11.8 degrees and solidity of 1.076. The cascade Reynolds number, based on blade chord, was 393,000. A moving end wall was used to simulate the relative motion between rotor and casing, and vortex generators attached to the moving end wall were used to produce an idealized periodic unsteady vortical inflow similar to that shed by the junction of a row of inlet guide vanes.
Measurements of the vortical inflow to the cascade produced by the generators and of the mean blade loading at the mid span are presented. The periodic and aperiodic behavior of the tip leakage flow downstream of the cascade, produced by this vortical disturbance, is also presented using phase and time averaged 3-component turbulence and pressure fluctuation measurements. These measurements are made for tip gap from 0.83% to 3.3% chord and streamwise locations from 0.772% to 1.117% blade spacing axially downstream of the cascade.
The phase averaged inflow measurements reveal that the inflow produced by the vortex generators consists of a pair asymmetric counter-rotating vortices embedded in a thin (4.6% chord) endwall boundary layer. The vortices extend some 7.4% chord from the end wall. Their strength is about two orders smaller than the typical circulation of the tip leakage vortices produced by the cascade.
Phase averaged single point three component hot-wire measurements downstream of the cascade reveal that the vortical inflow is, however, capable of producing significant large scale fluctuations in the size, strength, structure and position of the tip leakage vortex. These effects increase in magnitude with increase of tip gap. For small tip gaps these effects appear to be due to simple superposition between the inflow vortices and the tip leakage vortex. However for larger tip gaps these effects appear primarily a consequence of the inflow vortices interfering with the shedding of circulation from the blade tip. The fact that the circulation fluctuation is consistent with the inviscid unsteady loading prediction suggests that the inviscid response may be a major mechanism for generating the tip leakage unsteadiness.
Although there is large periodic fluctuation in the tip leakage flow disturbed by the inflow, there is a larger aperiodic component. Two point correlation measurements and linear stochastic estimation are used to reveal the structure of this aperiodic part for a tip gap of 3.3% chord. The aperiodic fluctuation, containing most of the turbulence energy, is found appearing to be organized structures in large scale, and making the estimated instantaneous velocity field significantly different from the phase averaged periodic velocity field.
Phase averaged pressure fluctuation measurements made using a microphone in the tip leakage vortex downstream of the cascade reveal that there are significant periodic fluctuating pressure waves and intense mean square fluctuation of the aperiodic fluctuating pressure. They are consistent with the measured periodic flow and aperiodic flow field respectively. These microphone measurements are validated using fluctuating pressure gradient estimates determined from the hot-wire measurements. / Ph. D.
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An Experimental Investigation of Unsteady Surface Pressure on Single and Multiple AirfoilsMish, Patrick Francis 15 April 2003 (has links)
This dissertation presents measurements of unsteady surface pressure on airfoils encountering flow disturbances. Analysis of measurements made on an airfoil immersed in turbulence and comparisons with inviscid theory are presented with the goal of determining the effect of angle of attack on an airfoils inviscid response. Unsteady measurements made on the surface of a linear cascade immersed in periodic flow are presented and analyzed to determine the relationship between the blades inviscid response and tip leakage vortex strength.
Measurements of fluctuating surface pressure were made on a NACA 0015 airfoil immersed in grid generated turbulence. The airfoil model has a 2' chord and spans the 6' Virginia Tech Stability Wind Tunnel test section. Two grids were used to investigate the effects of turbulence length scale on the surface pressure response. A large grid which produced turbulence with an integral scale 13% of the chord and a smaller grid which produced turbulence with an integral scale 1.3% of the chord. Measurements were performed at angles of attack from 0 to 20. An array of microphones mounted subsurface was used to measure the unsteady surface pressure. The goal of this measurement was to characterize the effects of angle of attack on the inviscid response.
Lift spectra calculated from pressure measurements at each angle of attack revealed two distinct interaction regions; for reduced frequencies < 10 a reduction in unsteady lift of up to 7 decibels (dB) occurs while an increase occurs for reduced frequencies > 10 as the angle of attack is increased. The reduction in unsteady lift at low reduced frequencies with increasing angle of attack is a result that has never before been shown either experimentally or theoretically. The source of the reduction in lift spectral level appears to be closely related to the distortion of inflow turbulence based on analysis of surface pressure spanwise correlation length scales. Furthermore, while the distortion of the inflow appears to be critical in this experiment, this effect does not seem to be significant in larger integral scale (relative to the chord) flows based on the previous experimental work of McKeough (1976) suggesting the airfoils size relative to the inflow integral scale is critical in defining how the airfoil will respond under variation of angle of attack.
A prediction scheme is developed that correctly accounts for the effects of distortion when the inflow integral scale is small relative to the airfoil chord. This scheme utilizes Rapid Distortion Theory to account for the distortion of the inflow with the distortion field modeled using a circular cylinder.
Measurement of the unsteady surface pressure response of a linear cascade in periodic disturbance is presented. Unsteady pressure was measured on the suction and pressure side of two cascade blades with an array of 24 microphones (12 per blade side) mounted subsurface. The periodic disturbance was generated using a pair of vortex generators attached to a moving end wall. Measurements were made for 8 tip gaps (t/c = 0.00825, 0.0165, 0.022, 0.033, 0.045, 0.057, 0.079, 0.129) and phased averaged with respect to the vortex generator pair position. This measurement was motivated by the results presented by Ma (2003). The work of Ma (2003) suggested that tip leakage vortex shedding in the presence of a periodic disturbance is heavily influenced by the inviscid response of the cascade blade. This conclusion was arrived at by Ma's (2003) observation that as the tip gap is increased the amount of fluctuation in the tip leakage vortex circulation increases dramatically, in fact, many times the circulation in the inflow vortices.
Unsteady pressure measurements reveal that the blade response involves a complex interaction of both inviscid response and viscous phenomena. However, a close relationship between unsteady tip loading and tip leakage vortex circulation is revealed suggesting the inviscid response is significant in determining the tip leakage vortex circulation. Additionally, predictions using inviscid theory agree well with measured levels of unsteady tip loading. As such, inviscid theory may be useful for predicting the tip leakage circulation and perhaps, pressure fluctuations in the tip leakage vortex. / Ph. D.
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Formation and Development of the Tip Leakage Vortex in a Simulated Axial Compressor with Unsteady InflowIntaratep, Nanyaporn 28 April 2006 (has links)
The interaction between rotor blade tip leakage vortex and inflow disturbances, such as encountered in shrouded marine propulsors, was simulated in the Virginia Tech Linear Cascade Wind Tunnel equipped with a moving endwall system. Upstream of the blade row, idealized periodic inflow unsteadiness was generated using vortex generator pairs attached to the endwall at the same spacing as the blade spacing. At three tip gap settings, 1.7%c, 3.3%c and 5.7%c, the flow near the lower endwall of the center blade passage was investigated through three-component mean velocity and turbulence distributions measured by four-sensor hotwires. Besides time-averaged data, the measurements were processed for phase-locked analysis, with respect to pitchwise locations of the vortex generators relative to the blade passage. Moreover, surface pressure distributions at the blade tip were acquired at eight tip gaps from 0.87%c to 12.9%c. Measurements of pressure-velocity correlation were also performed with wall motion but without inflow disturbances.
Achieved in this study is an understanding of the characteristics and structures of the tip leakage vortex at its initial formation. The mechanism of the tip leakage vortex formation seems to be independent of the tip gap setting. The tip leakage vortex consists of a vortical structure and a region of low streamwise-momentum fluid next to the endwall. The vortical structure is initially attached to the blade tip that creates it. This structure picks up circulation shed from that blade tip, as well as those from the endwall boundary layer, and becomes stronger with downstream distance. Partially induced by the mirror images in the endwall, the vortical structure starts to move across the passage resulting in a reduction in its rotational strength as the cross sectional area of the vortex increases but little circulation is added. The larger the tip gap, the longer the vortical structure stays attached to the blade tip, and the stronger the structure when it reaches downstream of the passage.
Phased-averaged data show that the inflow disturbances cause small-scale responses and large-scale responses upstream and downstream of the vortex shedding location, respectively. This difference in scale is possibly dictated by a variation in the shedding location since the amount of circulation in the vortex is dependent on this location. The inflow disturbances possibly cause a variation in the shedding location by manipulating the separation of the tip leakage flow from the endwall and consequently the flow's roll-up process. Even though this manipulation only perturbs the leakage flow in a small scale, the shedding mechanism of the tip leakage vortex amplifies the outcome. / Ph. D.
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Showerhead Film Cooling Performance of a Turbine Vane at High Freestream Turbulence in a Transonic CascadeNasir, Shakeel 01 September 2008 (has links)
One way to increase cycle efficiency of a gas turbine engine is to operate at higher turbine inlet temperature (TIT). In most engines, the turbine inlet temperatures have increased to be well above the metallurgical limit of engine components. Film cooling of gas turbine components (blades and vanes) is a widely used technique that allows higher turbine inlet temperatures by maintaining material temperatures within acceptable limits. In this cooling method, air is extracted from the compressor and forced through internal cooling passages within turbine blades and vanes before being ejected through discrete cooling holes on the surfaces of these airfoils. The air leaving these cooling holes forms a film of cool air on the component surface which protects the part from hot gas exiting the combustor.
Design optimization of the airfoil film cooling system on an engine scale is a key as increasing the amount of coolant supplied yields a cooler airfoil that will last longer, but decreases engine core flow—diminishing overall cycle efficiency. Interestingly, when contemplating the physics of film cooling, optimization is also a key to developing an effective design. The film cooling process is shown to be a complex function of at least two important mechanisms: Increasing the amount of coolant injected reduces the driving temperature (adiabatic wall temperature) of convective heat transfer—reducing heat load to the airfoil, but coolant injection also disturbs boundary layer and augments convective heat transfer coefficient due to local increase in freestream turbulence.
Accurate numerical modeling of airfoil film cooling performance is a challenge as it is complicated by several factors such as film cooling hole shape, coolant-to-freestream blowing ratio, coolant-to-freestream momentum ratio, surface curvature, approaching boundary layer state, Reynolds number, Mach number, combustor-generated high freestream turbulence, turbulence length scale, and secondary flows just to name a few. Until computational methods are able to accurately simulate these factors affecting film cooling performance, experimental studies are required to assist engineers in designing effective film cooling schemes.
The unique contribution of this research work is to experimentally and numerically investigate the effects of coolant injection rate or blowing ratio and exit Reynolds number/Mach number on the film cooling performance of a showerhead film cooled first stage turbine vane at high freestream turbulence (Tu = 16%) and engine representative exit flow conditions. The vane was arranged in a two-dimensional, linear cascade in a heated, transonic, blow-down wind tunnel. The same facility was also used to conduct experimental and numerical study of the effects of freestream turbulence, and Reynolds number on smooth (without film cooling holes) turbine blade and vane heat transfer at engine representative exit flow conditions. The showerhead film cooled vane was instrumented with single-sided platinum thin film gauges to experimentally determine the Nusselt number and film cooling effectiveness distributions over the surface from a single transient-temperature run. Showerhead film cooling was found to augment Nusselt number and reduce adiabatic wall temperature downstream of injection. The adiabatic effectiveness trend on the suction surface was also found to be influenced by a favorable pressure gradient due to Mach number and boundary layer transition region at all blowing ratio and exit Mach number conditions.
The experimental study was also complimented with a 3-D CFD effort to calculate and explain adiabatic film cooling effectiveness and Nusselt number distributions downstream of the showerhead film cooling rows of a turbine vane at high freestream turbulence (Tu = 16%) and engine design exit flow condition (Mex = 0.76). The research work presents a new three-simulations technique to calculate vane surface recovery temperature, adiabatic wall temperature, and surface Nusselt number to completely characterize film cooling performance in a high speed flow. The RANS based v2-f turbulence model was used in all numerical calculations. CFD calculations performed with experiment-matched boundary conditions showed an overall good trend agreement with experimental adiabatic film cooling effectiveness and Nusselt number distributions downstream of the showerhead film cooling rows of the vane. / Ph. D.
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Large Eddy Simulation of Shear-Free Interaction of Homogeneous Turbulence with a Flat-Plate CascadeSalem Said, Abdel-Halim Saber 07 August 2007 (has links)
Studying the effects of free stream turbulence on noise, vibration, and heat transfer on structures is very important in engineering applications. The problem of the interaction of large scale turbulence with a flat-plate cascade is a model of important problems in propulsion systems. Addressing the problem of large scale turbulence interacting with a flat plate cascade requires flow simulation over a large number of plates (6-12 plates) in order to be able to represent numerically integral length scales on the order of blade-to-blade spacing. Having such a large number of solid surfaces in the simulation requires very large computational grid points to resolve the boundary layers on the plates, and that is not possible with the current computing resources.
In this thesis we develop a computational technique to predict the distortion of homogeneous isotropic turbulence as it passes through a cascade of thin flat plates. We use Large-Eddy Simulation (LES) to capture the spatial development of the incident turbulence and its interaction with the plates which are assumed to be inviscid walls.
The LES is conducted for a linear cascade composed of six plates. Because suppression of the normal component of velocity is the main mechanism of distortion, we neglect the presence of mean shear in the boundary layers and wakes, and allow slip velocity on the plate surfaces. We enforce the zero normal velocity condition on the plates. This boundary condition treatment is motivated by rapid distortion theory (RDT) in which viscous effects are neglected, however, the present LES approach accounts for nonlinear and turbulence diffusion effects by a sub-grid scale model. We refer to this type of turbulence-blade interaction as shear-free interaction.
To validate our calculations, we computed the unsteady loading and radiated acoustic pressure field from flat plates interacting with vortical structures. We consider two fundamental problems: (1) A linear cascade of flat plates excited by a vortical wave (gust) given by a 2D Fourier mode, and (2) The parallel interaction of a finite-core vortex with a single plate. We solve the nonlinear Euler equations by a high-order finite-differece method. We use nonreflecting boundary conditions at the inflow and outflow boundaries. For the gust problem, we found that the cascade response depends sensitively on the frequency of the convicted gust. The unsteady surface pressure distribution and radiated pressure field agree very well with predictions of the linear theory for the tested range of reduced frequency. We have also investigated the effects of the incident gust frequency on the undesirable wave reflection at the inflow and outflow boundaries. For the vortex-plate interaction problem, we investigate the effects of the internal structure of the vortex on the strength and directivity of radiated sound.
Then we solved the turbulence cascade interaction problem. The normal Reynolds stresses and velocity spectra are analyzed ahead, within, and downstream of the cascade. Good agreement with predictions of rapid distortion theory in the region of its validity is obtained. Also, the normal Reynolds stress profiles are found to be in qualitative agreement with available experimental data. As such, this dissertation presents a viable computational alternative to rapid distortion theory (RDT) for the prediction of noise radiation due to the interaction of free stream turbulence with structures. / Ph. D.
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