Submitted by Mario Lopes (mariosilvalopes@gmail.com) on 2011-11-17T22:51:02Z No. of bitstreams: 1 DissertaçãoMSLFinal.pdf: 2601229 bytes, checksum: 8dd97b22637c4e3c6b2b47dfcab63218 (MD5) / Approved for entry into archive by Gisele Isaura Hannickel (gisele.hannickel@fgv.br) on 2011-11-18T10:41:59Z (GMT) No. of bitstreams: 1 DissertaçãoMSLFinal.pdf: 2601229 bytes, checksum: 8dd97b22637c4e3c6b2b47dfcab63218 (MD5) / Made available in DSpace on 2011-11-18T10:43:55Z (GMT). No. of bitstreams: 1 DissertaçãoMSLFinal.pdf: 2601229 bytes, checksum: 8dd97b22637c4e3c6b2b47dfcab63218 (MD5) Previous issue date: 2011-10-24 / O funcionamento dos bancos comerciais implica no sucesso de suas estratégias de captação de depósitos a prazo. O Certificado de Depósito Bancário (CDB) é um dos instrumentos mais utilizados para este fim. 95% dos CDBs são flutuantes e atrelados ao CDI, sendo que grande parte destes CDBs tem data de carência pré-definida para o resgate. Esta característica é responsável pela opção implícita de resgate oferecida ao investidor. Ou seja, o investidor tem a prerrogativa de resgatar seu investimento entre a data de carência e o vencimento do CDB sem que seja penalizado por isso. Este trabalho apresenta um método de apreçamento da opção de resgate implícita no CDB utilizando o modelo de Black Derman Toy. A técnica empregada inova ao considerar o nível da estrutura a termo de taxa de juros tanto em relação à curva de CDBs observada no mercado, quanto a sua volatilidade. Entretanto, a volatilidade é preservada e, por isso, não é contaminada pelas oscilações da estrutura a termo. No procedimento foram utilizados os CDBs do banco de dados da Cetip com valores maiores que quinhentos mil reais emitidos entre 2007 e 2009. Assumiu-se que todos os investidores eram racionais e não precisaram recorrer aos seus investimentos, portanto só resgataram seus recursos após o fim do prazo de carência. Com o intuito de verificar a validade dos preços calculados através do modelo Black Derman Toy, foi aplicada a técnica da simulação de Monte Carlo com a criação de dez mil trajetórias para o preço do ativo. Os resultados obtidos através do modelo proposto foram confirmados quando confrontados com a simulação de Monte Carlo. / The functioning of commercial banks relies on the success of their strategies to attract deposits. Time Deposits (TD) are one of the most used for this purpose. 95% of TDs have floating rates linked to Interbank Certificate of Deposits (CDI) and most of them have a pre-set grace date to the withdrawal. This feature is responsible for the embedded option offered to the investor. That is, the investor has the right to withdrawal their investment between the grace date and the TD maturity without being penalized. This paper presents a method of pricing withdrawal implied options in TDs using Black Derman Toy model. The innovative technique considers the level of the interest rates term structure in relation to TDs curve observed on the market, as well as its volatility. However, volatility is preserved, and therefore is not contaminated by term structure oscillations. In the procedure were used TDs (Cetip database) with amounts greater than five hundred thousand Reais issued between 2007 and 2009. It was assumed that all investors were rational and did not need to rely on their investments, so only withdrew them after their grace period. In order to verify the validity of the calculated prices by Black Derman Toy Model, Monte Carlo simulation technique was applied with the creation of ten thousand asset trajectories. Results obtained by the proposed model were confirmed when confronted with Monte Carlo simulation

The goal of this master’s thesis is to explore the possibilities of multichannel localization of acoustic signal sources and their following application on a real signal localization and separation, using Beamforming methods. During this thesis two beamforming methods were selected, namely Delay and Sum a Constant Directivity Beamforming - Circular Arrays, and were applicated on real environment signals using two microphone arrays’ geometries ULA (Uniform linear array) and UCA (Uniform Circular array).

We now report an in depth analysis of the successful in vitro enzymatic synthesis of PHB utilizing the three-enzyme system from the bacteria Cupriavidus necator. Using HPLC methodology developed in this laboratory, and by adding each enzyme in a step-wise manner, we follow each individual stage in the three-enzyme route for PHB synthesis and delineate all stoichiometric relationships. We report the construction of the first metabolic model developed specifically for analyzing in vitro enzymatic PHB synthesis. We developed a hands-on student laboratory for culturing, producing, isolating, and purifying the bacterial biopolyesters PHB. We now report the first structural characterizations of iso-CoA, acetyl-iso-CoA, acetoacetyl-iso-CoA, and beta-hydroxybutyryl-iso-CoA using MS, MS/MS, and homo- and hetero-nuclear NMR analyses.We describe HPLC methodology to separate the isomers of several iso-CoA-containing compounds and report the first examples of iso-CoA-containing compounds acting as substrates in enzymatic acyl-transfer reactions. We describe a simple regioselective synthesis of iso-CoA from CoA. We also demonstrate a plausible mechanism, which accounts for the existence of iso-CoA isomers in commercial preparations of CoA-containing compounds. Herein we report that phenylaminoethyl selenide compounds protect DNA from peroxynitrite-mediated single-strand breaks. The mechanism of protection against peroxynitrite mediated DNA damage was investigated by HPLC. The chemistry of the reaction between peroxynitrite and HOMePAES was investigated using HPLC and HPLC/MS. The unique chemistry of the reaction between peroxynitrite and HOMePAES was investigated using HPLC and HPLC/MS. We report the development of novel CDB derivatives, which are selective COX-II inhibitors. A series of compounds were assayed with an in vitro colorimetric inhibitor screening and with a whole blood ELISA screening and the results indicate that MST is a selective inhibitor of COX-II.