Made available in DSpace on 2014-12-17T15:36:53Z (GMT). No. of bitstreams: 1 FrancimarAS.pdf: 4205737 bytes, checksum: a4c2113c8c56b274ed7600ae2a39f704 (MD5) Previous issue date: 2008-09-26 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / The auditory system is composed by a set of relays from the outer ear to the cerebral cortex. In mammals, the central auditory system is composed by cochlear nuclei, superior olivary complex, inferior colliculus and medial geniculate body. In this study, the auditory rombencephalic centers, the cochlear nuclear complex and the superior olivary complex were evaluated from the cytoarchitecture and neurochemical aspects, thorough Nissl staining and immunohistochemical techniques to reveal specific neuron nuclear protein (NeuN), glutamate (Glu), glutamic acid decarboxilase (GAD), enkephalin (ENK), serotonin (5-HT), choline acetyltransferase (ChAT) and calcium-binding proteins calbindin (CB), calretinin (CR), and parvalbumin (PV). The common marmoset (Callithrix jacchus), a little native primate of the Brazilian atlantic forest was used as an experimental animal. As results, it was noted that the cochlear nuclear complex is composed by anteroventral, posteroventral and dorsal nuclei, and the superior olivary complex is constituted by the lateral and medial superior olivary nuclei and the trapezoid body nucleus. Glu, GAD, ENK, ChAT, CB, CR, PV-immunoreactive cells, fibers and terminals besides besides only 5-HT terminals were found unhomogeneously in all nuclei, of both complex. The emerging data are discussed in a comparative and functional context, and represent an important contribution to knowledge of the central auditory pathways in the common marmoset, and then in primates / O sistema auditivo compreende uma s?rie de esta??es que se estendem desde a orelha externa at? o c?rtex cerebral. Em mam?feros o sistema auditivo central subcortical ? formado essencialmente por n?cleos cocleares, complexo olivar superior, col?culo inferior e corpo geniculado medial. Neste estudo, os centros rombencef?licos, compreendendo o complexo nuclear coclear e o complexo olivar superior foram avaliados com rela??o a sua citoarquitetura e conte?do neuroqu?mico de corpos celulares e terminais ax?nicos, atrav?s das t?cnicas de colora??o de Nissl e imuno-histoqu?mica para prote?na nuclear neur?nio espec?fica (NeuN), glutamato (Glu), descaboxilase de ?cido glut?mico (GAD), encefalina (ENK), serotonina (5-HT), colina acetiltransferase (ChAT) e prote?nas ligantes de c?lcio calbindina (CB), cal-retinina (CR) e parvalbumina (PV). Foi utilizado como animal experimental o sag?i (Callithrix jacchus), um pequeno primata nativo da Mata Atl?ntica do Nordeste Brasileiro. Como resultados, foi evidenciado que o complexo nuclear coclear ? composto pelos n?cleos cocleares antero-ventral, p?stero-ventral e dorsal, e o complexo olivar superior pelos n?cleos olivares superiores lateral e medial e o n?cleo do corpo trapez?ide. Em todos os n?cleos, de ambos os complexos, foram encontrados de forma vari?vel corpos celulares, fibras e terminais imunorreativos a Glu, GAD, ChAT, CB, CR, PV, corpos celulares e terminais imunoreativos a ENK, al?m de fibras e terminais imunorreativos a 5-HT em diferentes densidades. Os dados obtidos s?o discutidos dentro de um contexto comparativo e funcional e representam uma importante contribui??o ao conhecimento das vias auditivas centrais no sag?i, e por extens?o em primatas