我們從計算股價的相關矩陣，然後利用隨機矩陣定理的結果，了解到股票市場並非符合隨機過程的預測，進而得知股票對股票之間具有關聯性，然其長時距下股票價格對數報酬的變化會呈現隨機行走的模式，因此我們對其結果提出二種不同的耦合隨機行走模型，試圖闡釋股票市場間的關聯性可融合到耦合隨機行走模型之中，並藉由均方對數報酬(mean square log-return，MSLR)來探討此事情。 最後，為了瞭解關聯性的關係，並利用其來了解股票市場內部結構的特性，因此我們利用股價的相關矩陣來建構最小展開樹進行分析，發現當時間尺度越大其圖形越密集，中心幾乎為「GE」這家公司，因此其股票市場具有一定的判斷指標。 / By means of calculating the correlation matrix of the price of stock and using the results of random matrix theorems，we learned that the stock market does not match the prediction of stochastic processes and the stock-stock is correlated。However，stock’s price log-return changes under long time scale will appear random walk model. Therefore，we propose two kinds of the different coupled random walk model，that try to explain the correlation between the stock markets can be integrated into the coupled random walk model，and using the mean square log-return( MSLR) to investigate this issue。 Finally，to understand the relationship of correlation matrix and by using it to know the characteristics of the underlying structure of the stock market，we use the correlation matrix of the price to construct the minimum spanning tree for analysis。The results showed that when the time scale is greater, the graphics are more intensive，and the center is almost the same company，"GE"， indicating that the stock market has a certain judgment index。

Due to the emergence of new materials and advanced engineering technology, slender footbridges are increasingly becoming popular to satisfy the modern transportation needs and the aesthetical requirements of society. These structures however are always &quotlively" with low stiffness, low mass, low damping and low natural frequencies. As a consequence, they are prone to vibration induced by human activities and can suffer severe vibration serviceability problems, particularly in the lateral direction. This phenomenon has been evidenced by the excessive lateral vibration of many footbridges worldwide such as the Millennium Bridge in London and the T-Bridge in Japan. Unfortunately, present bridge design codes worldwide do not provide sufficient guidelines and information to address such vibrations problems and to ensure safety and serviceability due to the lack of knowledge on the dynamic performance of such slender vibration sensitive bridge structures. A conceptual study has been carried out to comprehensively investigate the dynamic characteristics of slender suspension footbridges under human-induced dynamic loads and a footbridge model in full size with pre-tensioned reverse profiled cables in the vertical and horizontal planes has been proposed for this purpose. A similar physical suspension bridge model was designed and constructed in the laboratory, and experimental testings have been carried out to calibrate the computer simulations. The synchronous excitation induced by walking has been modelled as crowd walking dynamic loads which consist of dynamic vertical force, dynamic lateral force and static vertical force. The dynamic behaviour under synchronous excitation is simulated by resonant vibration at the pacing rate which coincides with a natural frequency of the footbridge structure. Two structural analysis software packages, Microstran and SAP2000 have been employed in the extensive numerical analysis. Research results show that the structural stiffness and vibration properties of suspension footbridges with pre-tensioned reverse profiled cables can be adjusted by choosing different structural parameters such as cable sag, cable section and pretensions in the reverse profiled cables. Slender suspension footbridges always have four main kinds of vibration modes: lateral, torsional, vertical and longitudinal modes. The lateral and torsional modes are often combined together and become two kinds of coupled modes: coupled lateral-torsional modes and coupled torsionallateral modes. Such kind of slender footbridges also have different dynamic performance in the lateral and vertical directions, and damping has only a small effect on the lateral vibration but significant effect on the vertical one. The fundamental coupled lateral-torsional mode and vertical mode are easily excited when crowd walking dynamic loads are distributed on full bridge deck. When the crowd walking dynamic loads are distributed eccentrically on half width of the deck, the fundamental coupled torsional-lateral mode can be excited and large lateral deflection can be induced. Higher order vertical modes and coupled lateral-torsional modes can also be excited by groups of walking pedestrians under certain conditions. It is found that the coupling coefficient introduced in this thesis to describe the coupling of a coupled mode, is an important factor which has significant effect on the lateral dynamic performance of slender suspension footbridges. The coupling coefficient, however, is influenced by many structural parameters such as cable configuration, cable section, cable sag, bridge span and pre-tensions, etc. In general, a large dynamic amplification factor is expected when the fundamental mode of a footbridge structure is the coupled lateral-torsional mode with a small coupling coefficient. The research findings of this thesis are useful in understanding the complex dynamic behaviour of slender and vibration sensitive suspension footbridges under humaninduced dynamic loads. They are also helpful in developing design guidance and techniques to improve the dynamic performance of such slender vibration sensitive footbridges and similar structures and hence to ensure their safety and serviceability.

[Truncated abstract] Rocks, as the host to natural chains of coupled thermal, hydraulic and mechanical processes, are heterogeneous at a variety of length scales, and in their mechanical properties, as well as in the hydraulic and thermal transport properties. Rock heterogeneity affects the ultimate hydro-carbon recovery or geothermal energy production. This heterogeneity has been considered one important and difficult problem that needs to be taken into account for its effect on the coupled processes. The aim of this thesis is to investigate the effect of rock heterogeneity on multi-physical processes. A fully coupled finite element model, hereinafter referred to as a porosity-based model (PBM) was developed to characterise the thermal-hydraulic-mechanical (THM) coupling processes. The development of the PBM consists of a two-staged workflow. First, based on poromechanics, porosity, one of the inherent rock properties, was derived as a variant function of the thermal, hydraulic and mechanical effects. Then, empirical relations or experimental results, correlating porosity with the mechanical, hydraulic and thermal properties, were incorporated as the coupling effects. In the PBM, the bulk volume of the model is assumed to be changeable. The rate of the volumetric strain was derived as the difference of two parts: the first part is the change in volume per unit of volume and per unit of time (this part was traditionally considered the rate of volumetric strain); and the second is the product of the first part and the volumetric strain. The second part makes the PBM a significant advancement of the models reported in the literature. ... impact of the rock heterogeneity on the hydro-mechanical responses because of the requirement of large memory and long central processing unit (CPU) time for the 3D applications. In the 2D PBM applications, as the thermal boundary condition applied to the rock samples containing some fractures, the pore pressure is generated by the thermal gradient. Some pore pressure islands can be generated as the statistical model and the digital image model are applied to characterise the initial porosity distribution. However, by using the homogeneous model, this phenomenon cannot be produced. In the 3D PBM applications, the existing fractures become the preferential paths for the fluid flowing inside the numerical model. The numerical results show that the PBM is sufficiently reliable to account for the rock mineral distribution in the hydro-mechanical coupling processes. The applications of the statistical method and the digital image processing technique make it possible to visualise the rock heterogeneity effect on the pore pressure distribution and the heat dissipation inside the rock model. Monitoring the fluid flux demonstrates the impact of the rock heterogeneity on the fluid product, which concerns petroleum engineering. The overall fluid flux (OFF) is mostly overestimated when the rock and fluid properties are assumed to be homogeneous. The 3D PBM application is an example. As the rock is heterogeneous, the OFF by the digital core is almost the same as that by the homogeneous model (this is due to that some fractures running through the digital core become the preferential path for the fluid flow), and around 1.5 times of that by the statistical model.

Diss. (sammanfattning) Uppsala : Uppsala universitet, 2008. / Härtill 6 uppsatser.

Thesis (Ph.D. in Immunology) -- University of Colorado Denver, 2007. / Typescript. Includes bibliographical references (leaves 103-118). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;

This work focuses in two main directions of rotor dynamics field, the simulation of rotor bearing systems and the fault diagnosis. From the serious multiple faults that can appear in a rotor bearing system two of them are the target of current research: the transverse fatigue crack of a rotor and the radial extended wear in a bearing. The transverse crack is a defect able to bring a catastrophic failure of the system when the growth (depth) takes high percentage values relatively to radius of the shaft (i.e. >60%) and the symptoms of crack presence have been widely investigated during last four decades yielding efficient methods for the early crack detection. On the other hand the defect of bearing wear is much less investigated without results connected with wear diagnosis methods. Concerning previous works in those two defects the current dissertation’s persuasion is firstly to make a proposal in bearing wear detection, secondly to achieve a method definition able to detect a breathing transverse crack in a different way from those referred to literature. For the subject of crack detection, a different crack breathing model is proposed with emphasis in coupled local compliances definition and their variation during rotation while for the subject of bearing wear detection, a wear model from the literature is used with emphasis in rotor bearing system construction in a different way in relation to what up to now is available in literature. The rotor bearing system construction (simulation) is a matter widely investigated since early 60’s and some points of the current work try to differ in the way that the rotor and the fluid film bearings interact in discrete time. The concept of nonlinear fluid film forces is confronted in this work leaving out the nonlinear stiffness and damping bearing fluid film coefficients and assuming that during the journal whirling no equilibrium point must be defined in order to evaluate the future progress of vibration. Towards generality the fluid film bearings are not defined geometrically as short or long. These two specific geometric assumptions of short/long bearing appear widely in real machines and yield analytical expressions of fluid film forces but in current work the finite fluid film bearing is used demanding the well known finite difference method in order to evaluate the impedance forces, as many researches have propose. Both defects are met in a rotor bearing system parted from a continuous rotor and finite fluid film bearings. An entire chapter is dedicated in the way that Rayleigh equation of rotor motion incorporates internal damping using exclusively Real number confrontment, and in the way that fluid film forces react in rotor motion by defining boundary conditions in every discrete time moment. The definition of boundary conditions in discrete time makes them functions of the entire system response yielding a nonlinear dynamic system with the resulting time xx histories to be characterized from periodicity or quasi-periodicity sometimes depending in the defects presence. An extended analysis of time histories of the intact and the defected system is made in order to invest the symptoms of each defect in magnitudes of time and frequency domain. Timefrequency analysis is performed using continuous wavelet transform in virtually or really (the former from simulation, the latter from experiment) acquired time histories in order to extract the variable coupling phenomenon exclusively due to the breathing crack from the other two main reasons of coupling, the bearings and the shaft. Vertical response due to crack coupling is amplified when the crack coupled compliances become larger under an electromagnetic horizontal excitation in the rotor. This rapid in time variable coupling due to crack is used at last in order to detect the crack presence. The external excitation is used also in the case of wear detection since results of time-frequency analysis yield unexpected amplification of specific harmonics when the wear defect is present. Both considerations about the corresponding fault detection are tried in a real experimental system after the observation that response of the current rotor bearing simulation converges with the response of the physical system in characteristics that are judged important for the method robustness. The general speculation is that both defects have to be detected without the need of operation interruption since this cannot be feasible (high cost) in real turbo machinery plants and in an early growth that coincides with safe machine operation. The defect growths have to be at least 10% (of radius) for the crack and 20% (of radial clearance) for bearing wear so as the methods to be efficient. / Η συγκεκριμένη διατριβή επικεντρώνεται κυρίως σε δύο κατευθύνσεις του αντικειμένου της δυναμικής των περιστρεφόμενων αξόνων: την προσομοίωση συστημάτων αξόνων και εδράνων και την ανίχνευση βλαβών σ΄αυτά τόσο σε αναλυτικό όσο και σε πειραματικό επίπεδο. Από τις συνήθως απαντώμενες βλάβες σε τέτοια συστήματα δύο από αυτές αποτελούν στόχους για τη συγκεκριμένη εργασία: η εγκάρσια ρωγμή λόγω κόπωσης του άξονα και η ακτινική φθορά των εδράνων ολίσθησης. Η εγκάρσια ρωγμή είναι μία βλάβη ικανή να επιφέρει ολοκληρωτική καταστροφή της μηχανής στην οποία παρουσιάζεται, όταν η έκτασή της υπερβαίνει το 60% περίπου της διαμέτρου και τα συμπτώματα της ρωγμής στην ταλαντωτική συμπεριφορά του συστήματος έχουν εκτενώς διερευνηθεί τις τελευταίες δεκαετίες, με αποτέλεσμα την ανάπτυξη ποικίλων μεθόδων για την έγκαιρη ανίχνευση της βλάβης. Αντιθέτως, η φθορά των εδράνων αποτελεί μία βλάβη πολύ λιγότερο διερευνημένη συγκριτικά με τη ρωγμή, χωρίς αποτελέσματα για την διάγνωσή της κατά τη λειτουργία της μηχανής. Έχοντας υπ’ όψη τις εργασίες των προηγουμένων ετών στο αντικείμενο της ανίχνευσης αυτών των δύο βλαβών, η παρούσα διατριβή έχει ως στόχο πρωτίστως να προτείνει μεθόδους για την ανίχνευση της φθοράς του εδράνου και δευτερευόντως να επιτύχει την ανίχνευση της ρωγμής με ένα διαφορετικό ως προς τη φιλοσοφία, και απλό ως προς την εφαρμογή τρόπο, αναφορικά με τις μέχρι σήμερα μεθόδους. Για το αντικείμενο της ανίχνευσης της ρωγμής, προτείνεται αρχικά μία διαφορετική προσομοίωση της συμπεριφοράς της κατά την περιστροφή με έμφαση στον υπολογισμό των τοπικών ενδοτικοτήτων σύζευξης κατά την διάρκεια της λειτουργίας του συστήματος, ενώ για το αντικείμενο της ανίχνευσης της φθοράς χρησιμοποιείται ένα ήδη υπάρχον μοντέλο από τη βιβλιογραφία. Και οι δύο βλάβες ενσωματώνονται σε μία νέα ως προς τη βιβλιογραφία προσομοίωση συστήματος αξόνων και εδράνων η οποία αντιμετωπίζει τον άξονα και τα έδρανα ως ένα ενιαίο σύστημα χρησιμοποιώντας τις πιο ακριβείς έως τώρα προσεγγίσεις ταλάντωσης συνεχούς μέσου και της υδροδυναμικής θεωρίας των εδράνων. Η προσομοίωση συστημάτων αξόνων και εδράνων είναι ένα ζήτημα ευρέως διερευνημένο από τις αρχές της δεκαετίας του ΄60 και ορισμένα στοιχεία της παρούσας διατριβής, πάνω στην αντιμετώπιση του θέματος αυτού, έχουν ως στόχο τη βελτίωση με την παρούσα ανάλυση της υπάρχουσας γνώσης, για τον τρόπο που έδρανο και άξονας αλληλεπιδρούν σε διακριτό χρόνο. xxii Το θέμα των μη γραμμικών δυνάμεων του φιλμ λιπαντικού των εδράνων αντιμετωπίζεται σε αυτή τη διατριβή υπολογίζοντας κατευθείαν τις μη γραμμικες δυνάμεις που ασκούνται από το φιλμ στον άξονα. Η παραδοχή αυτή βοηθάει την προσομοίωση ιδιαίτερα σε περιπτώσεις που δεν υπάρχει σημείο ισσοροπίας λόγω περιδήνησης μεγάλου εύρους ή λειτουργείας σε κρίσιμη ταχύτητα. Επίσης, για λόγους γενικότητας και πληρότητας της προσομοίωσης, δεν γίνεται η κατά κόρον κατά τη βιβλιογραφία παραδοχή του εδράνου απείρου μήκους (infinitely long bearing) ή του εδράνου αμελητέου μήκους (infinitely short bearing). Αυτές οι δύο ακραίες υποθέσεις για το έδρανο επιτρέπουν αναλυτικές εκφράσεις για τη υδροδυναμική λίπανση αλλά δεν απαντώνται απαραίτητα στην πραγματικότητα. Στην παρούσα διατριβή χρησιμοποιούνται πεπερασμένα έδρανα τα οποία επιλύονται με ήδη γνωστό και αξιόπιστο τρόπο, όπως πολλοί ερευνητές έχουν προτείνει, χρησιμοποιώντας τη μέθοδο των πεπερασμένων διαφορών. Η ανάγκη για την παρουσία εσωτερικής (υστερητικής) απόσβεσης στην προσομοίωση του συνεχούς άξονα είναι αναπόφευκτη, από τη στιγμή που απαιτούνται λύσεις πάνω στο συντονισμό, ούτως ώστε να αναδειχθούν οι επιδράσεις των βλαβών, που στη περιοχή του συντονισμού γίνονται εντονώτερες. Ο απειρισμός της απόκρισης, απουσία εσωτερικής απόσβεσης, δεν αφήνει περιθώρια για διερεύνηση των επιπτώσεων των βλαβών πάνω στην κατάσταση συντονισμού και για το λόγο αυτό η εσωτερική υστερητική απόσβεση ενσωματώνεται προκειμένου να επιτρέψει υπολογισμό της απόκρισης. Ο τρόπος με τον οποίο εισάγεται η υστερητική απόσβεση δεν διαφοροποιείται από τη βιβλιογραφία καθώς η απόσβεση εισάγεται με τη χρήση του μιγαδικού μέτρου ελαστικότητας και διάτμησης αλλά η επίλυση του προβλήματος αντιμετωπίζεται με τη χρήση μόνο πραγματικών αριθμών προκειμένου να είναι εφικτή η εισαγωγή των εδράνων στο σύστημα. Διεξάγεται μια εκτεταμένη ανάλυση των χρονοσειρών του συστήματος με και χωρίς βλάβη, προκειμένου να διερευνηθούν τα συμπτώματα κάθε βλάβης στα πεδία χρόνου και συχνότητας. Η ανάλυση χρόνου-συχνότητας εκτελείται χρησιμοποιώντας το Συνεχή Μετασχηματισμό Wavelets (CWT) στις πειραματικές και αναλυτικές χρονοσειρές προκειμένου να εξαχθεί το μεταβλητό φαινόμενο συζεύξεων που οφείλεται αποκλειστικά στην ανοιγοκλείνουσα ρωγμή, από τους άλλους δύο κύριους λόγους της σύζευξης, δηλ. αυτούς των ανισότροπων εδράνων και των συζευγμένων εξισώσεων του περιστρεφόμενου άξονα. Εδώ χρησιμοποιήθηκε η ιδέα της χρήσης εξωτερικού ηλεκτρομαγνητικού διεγέρτη οριζόντιας διεύθυνσης, κατάλληλης συχνότητας και εύρους, ώστε να αναδειχθούν χαρακτηριστικά των βλαβών κατά τη λειτουργία. Η κατακόρυφη απόκριση, εξ αιτίας της σύζευξης ταλαντώσεων λόγω της ρωγμής, ενισχύεται όταν η ρωγμή βρίσκεται σε θέση όπου οι ενδοτικότητες σύζευξης γίνονται μεγαλύτερες, σε σχέση με την οριζόντια διεύθυνση xxiii εφαρμογής της ηλεκτρομαγνητικής διέγερσης στον άξονα. Αυτή η μεταβλητή σύζευξη παρουσιάζεται μόνο λόγω της ρωγμής και χρησιμοποιείται τελικά για την ανίχνευσή της. Η εξωτερική διέγερση χρησιμοποιείται επίσης και στην περίπτωση της ανίχνευσης φθοράς, δεδομένου ότι η ανάλυση των ταλαντώσεων στο πεδίο του χρόνου ή της συχνότητας, δείχνει ότι ενισχύονται συγκεκριμένες αρμονικές όταν η φθορά υπεισέρχεται στο σύστημα. Και οι δύο μέθοδοι για την αντίστοιχη ανίχνευση των βλαβών δοκιμάζονται σε ένα πραγματικό πειραματικό σύστημα. Η φιλοσοφία της μεθόδου ανίχνευσης των βλαβών βασίζεται στο ότι και οι δύο βλάβες πρέπει να ανιχνευθούν κατά τη λειτουργία του συστήματος. Πράγματι, υπάρχει η ανάγκη για έγκαιρη διάγνωση των βλαβών, σε πρώϊμο στάδιό τους, στο χρονικό διάστημα που μεσολαβεί ανάμεσα σε δύο διαδοχικές συντηρήσεις διασφαλίζοντας την ασφαλή λειτουργία των μηχανών. Η έκταση των προς ανίχνευση βλαβών πρέπει να είναι τουλάχιστον 20% (της ακτίνας) για τη ρωγμή και 20% (της ακτινικής χάρης) για την φθορά έτσι ώστε η μέθοδος ανίχνευσης να χαρακτηρίζεται αποδοτική. Οι κύριοι στόχοι της παρούσας διατριβής είναι: Η προσομοίωση ενός περιστρεφομένου και εσωτερικά αποσβενύμενου συνεχούς άξονα, εδραζομένου σε φθαρμένα ή μη πεπερασμένα έδρανα ολίσθησης. Η προσομοίωση και ο υπολογισμός των τοπικών καμπτικών ενδοτικοτήτων σύζευξης της περιστρεφόμενης ανοιγοκλείνουσας ρωγμής και η προσομοίωση των συζευγμένων ταλαντώσεων του ρηγματωμένου συστήματος άξονα-εδράνων. Η αναλυτική και πειραματική εφαρμογή του ρηγματωμένου και του φθαρμένου συστήματος και η διερεύνηση των επιδράσεων της ρωγμής και της φθοράς στην ταλαντωτική του συμπεριφορά. Η ανάπτυξη μεθόδων έγκαιρης ανίχνευσης της ρωγμής και της φθοράς.

Melanopsin (Opn4) is the opsin photopigment of intrinsically photosensitive retinal ganglion cells (ipRGCs). It has a conserved opsin structure and activation mechanism, yet demonstrates unusual functional properties that suggest it will possess unique structure-function relationships. The aim of this thesis was to characterise key OPN4 residues by examining the impact of non-synonymous mutations on melanopsin function. A genotype-driven screen of a chemically-mutagenized mouse archive led to the identification of a novel Opn4 mutant, S310A, located at a known opsin spectral tuning site. Action spectra from ipRGC and pupil light responses (PLR) of Opn4^S310A mice revealed no change in wavelength of peak sensitivity. However, Opn4^S310A PLR was significantly less sensitive at longer wavelengths, consistent with a short-wavelength shift in spectral sensitivity. This suggests S310A acts as a spectral tuning site in melanopsin. Next, the impact of naturally-occurring missense variants in human melanopsin (hOPN4) was examined in vitro. Fluorescent calcium imaging of 16 hOPN4 variants expressed in HEK293 cells revealed four hOPN4 variants abolished or attenuated responses to light (Y146C, R168C, G208S and S308F). These variants were located in conserved opsin motifs for chromophore binding or hydrogen-bond networks, functional roles apparently shared by melanopsin. Finally, two hOPN4 single nucleotide polymorphisms (SNPs) P10L and T394I, associated with abnormal non-image forming behaviour in humans, were explored in vivo. Using targeted viral-delivery of hOPN4 SNPs to mouse ipRGCs, a range of OPN4-driven behaviours, such as circadian photoentrainment and pupil light responses, were found to be comparable with hOPN4 WT control. Multi-electrode array recordings of ipRGCs transduced with hOPN4 T394I virus had significantly attenuated sensitivity and faster response offset, indicating this site may be functionally important for melanopsin activity but compensatory rod and cone input limits changes to non-image forming behaviour.

Vibratory gyroscopes have gained immense popularity in the microsystem technology because of their suitability to planar fabrication techniques. With considerable effort in design and fabrication, MEMS (Micro-electro-mechanical-system) vibratory gyroscopes have started pervading consumer electronics apart from their well known applications in aerospace and defence systems. Vibratory gyroscopes operate on the Coriolis principle for sensing rates of rotation of the r tating body. They typically employ capacitive or piezoresistive sensing for detecting the Coriolis force induced motion which is, in turn, used to determine the impressed rate of rotation. Interestingly, Nature also uses vibratory gyroscopes in its designs. Over several years, it has evolved an incredibly elegant design for vibratory gyroscopes in the form of dipteran halteres. Dipterans are known to receive mechanosensory feedback on their aerial rotations from halteres for their flight navigation. Insect biologists have also studied this sensor and continue to be fascinated by the intricate mechanism employed to sense the rate of rotation. In most Diptera, including the soldier fly, Hermetia illucens, the halteres are simple cantilever like structures with an end mass that probably evolved from the hind wings of the ancestral four-winged insect form. The halteres along with their connecting joint with the fly’s body constitute a mechanism that is used for muscle-actuated oscillations of the halteres along the actuation direction. These oscillations occur in the actuation plane such that any rotation of the insect body, induces Coriolis force on the halteres causing their plane of vibration to shift laterally by a small degree. This induced deflection along the sensing plane (out of the haltere’s actuation plane) results in strain variation at the base of the haltere shaft, which is sensed by the campaniform sensilla. The goal of the current study is to understand the strain sensing mechanism of the haltere, the nature of boundary attachments of the haltere with the fly’s body, the reasons of asymmetrical geometry of the haltere, and the interaction between both wings and the contralateral wing and haltere. In order to understand the haltere’s strain sensing mechanism, we estimate the strain pattern at the haltere base induced due to rotations about the body’s pitch, roll, and yaw axes. We model the haltere as a cantilever structure (cylindrical stalk with a spherical end knob) with experimentally determined material properties from nanoindentation and carry out analytical and numerical (finite element) analysis to estimate strains in the haltere due to Coriolis forces and inertia forces resulting from various body rotations. From the strain pattern, we establish a correlation between the location of maximum strain and the position of the campaniform sensilla and propose strain sensing mechanisms. The haltere is connected to the meta thoracic region of the fly’s body by a complicated hinge mechanism that actuates the haltere into angular oscillations with a large amplitude of 170 ◦ in the actuation plane and very small oscillation in the sensing plane. We aim to understand the reason behind the dissimilar boundary attachments along the two directions. We carry out bending experiments using micro Newton force sensor and estimate the stiffness along the actuation and sensing directions. We observe that the haltere behaves as a rigid body in the actuation direction and a flexible body in the sensing direction. We find the haltere to be a resonating structure with two different kinds of boundary attachments in the actuation and sensing directions. We create a finite element model of the haltere joint based on the optical and scanning microscope images, approximate material properties, and stiffness properties obtained from the bending experiments. We subsequently validate the model with experimental results. The haltere geometry has asymmetry along the length and the cross-section. This specific design of the haltere is in contrast to the the existing MEMS vibratory gyroscope, where the elastic beams supporting the proof mass are typically designed with symmetric cross-sections so that there is a mode matching between the actuation and the sensing vibrations. The mode matching provides high sensitivity and low bandwidth. Hence, we are interested in understanding the mechanical significance of the haltere’s asymmetry. First, we estimate the location of the maximum stress by using the actual geometry of the haltere. Next, by using the stiffness determined from bending experiments and mass properties from the geometric model, we find the natural frequencies along both actuation and sensing directions. We compare these findings with existing MEMS vibratory gyroscopes. The dipteran halteres always vibrate at the wing beat frequency. Each wing maintains 180 ◦ phase difference with its contralateral haltere and the opposite wing. Both wings and the contralateral wing-haltere mechanism exhibit coupled oscillatory motion through passive linkages. These linkages modulate the frequency and maintain the out- of-phase relationship. We explore the dynamics behind the out-of-phase behaviour and the frequency modulation of the wing-wing and wing-haltere coupled oscillatory motion. We observe that the linear coupled oscillatory model can explain the out-of-phase relationship between the two wings. However, a nonlinear coupled oscillator model is required to explain both frequency synchronization and frequency modulation of the wing with the haltere. We also carry out a finite element analysis of the wing-haltere mechanism and show that the out-of-phase motion between the wing and the haltere is due to the passive mechanical linkage of finite strength and high actuation force. The results of this study reveal the mechanics of the haltere as a rate sensing gyroscope and show the basis of the Nature’s design of this elegant sensor. This study brings out two specific features— the large amplitude actuated oscillations and the asymmetric geometry of the haltere structure— that are not found in current vibratory gyroscope designs. We hope that our findings inspire new designs of MEMS gyroscopes that have elegance and simplicity of the haltere along with the desired performance.

Les études de faisabilité concernant le stockage géologique profond des déchets radioactifs ont conduit un intérêt accru concernant la modélisation géomécanique de la roche hte. En France, une roche hte potentielle est l'argilite du Callovo-Oxfordien du site de Meuse/Haute Marne. Etant donné que le principe de stockage géologique profond repose fortement sur la capacité de confinement de la formation hte, sa faible perméabilité est d'une importance clé. La perméabilité étant dépendante de la microstructure du matériau et de son évolution sous chargement, le comportement couplé hydro-mécanique de l'argilite est important. En effet, des modifications mécaniques sont induites par le creusement de la galerie d'entreposage, générant une zone endommagée (EDZ), pouvant conduire une modification de la perméabilité dans le voisinage de la galerie. Dans les matériaux microstructure complexe comme l'argilite du Callovo-Oxfordien, le comportement macroscopique trouve son origine dans l'interaction des constituants micro-mécaniques. En plus du couplage entre le comportement hydraulique et mécanique, un couplage entre les échelles micro et macro existe. Par le biais de l'élaboration d'un cadre d'homogénéisation du couplage hydro-mécanique, une approche de modélisation deuxéchelles est développée dans ce travail, dans laquelle la relation constitutive macroscopique découle directement du comportement à l'échelle microscopique. Un modèle existant du couplage hydro-mécanique, reposant sur l'identification de grains et d'espaces poreux intergranulaires à l'échelle micro est adopté comme point de départ. Ce modèle repose sur une homogénéisation numérique du comportement à la petite échelle afin d'obtenir à l'échelle macroscopique la réponse en contrainte et de transport du fluide interstitiel. Ce modèle est basé sur un VER périodique qui permet de déduire le comportement macroscopique local de l'argilite. En réponse, en un point d'intégration macro donné, à un incrément de la déformation et du gradient de pression, la réponse du VER permet d'exprimer l'incrément de contrainte et de flux associé, constituant de fait un équivalent numérique de la relation constitutive. Les problèmes aux conditions limites macro et micro sont traités simultanément par la méthode élément fini. Pour obtenir les opérateurs tangents consistants à l'échelle macro, la méthode d'homogénéisation par condensation statique des opérateurs tangeants micro est étendu au cas avec couplage hydro-mécanique. L'implémentation du modèle double échelle et la mise en uvre des développements théoriques d'homogénéisation ont été effectués dans le code élément fini Lagamine (Université de Liège). Pour la modélisation de la localisation de la déformation à l'échelle macro, qui, dans un formalisme de milieu continu classique, souffre de la dépendance au maillage, l'approche double-échelle a été utilisée dans un formalisme de milieu enrichi de type milieu de second gradient pour matériau poreux saturé. Les capacités du modèle homogénéisé numériquement, utilisé dans un cadre de milieu de second gradient, sont ensuite démontrées par des simulations d'essais dométriques et d'essais de compression biaxiaux. L'approche se confirme être un moyen puissant pour modéliser l'anisotropie initiale et induite du comportement mécanique et du comportement hydraulique. Pour la modélisation du comportement de l'argilite du Callovo-Oxfordien, des VER sont construits en tenant compte des travaux de caractérisation de la géométrie des inclusions microscopiques et des résultats expérimentaux d'essais macroscopiques.La loi de comportement homogénéisée numériquement ainsi calibrée est utilisée dans des simulations de creusement de galerie jusqu'à des niveaux d'endommagement générant une localisation de la déformation.Ces calculs montrent à la fois la pertinence et l'applicabilité du concept double échelle pour l'évaluation du comportement hydromécanique des EDZ dans un contexte du stockage des déchets radioactifs. / Feasibility studies for deep geological radioactive waste disposal facilities have led to an increased interest in the geomechanical modelling of its host rock. In France, a potential host rock is the Callovo-Oxfordian claystone. The low permeability of this material is of key importance, as the principal of deep geological disposal strongly relies on the sealing capacity of the host formation. The permeability being coupled to the mechanical material state, hydromechanical coupled behaviour of the claystone becomes important when mechanical alterations are induced by gallery excavation in the so-called excavation damaged zone (EDZ). In materials with microstructure such as the Callovo-Oxfordian claystone [Robinet et al., 2012], the macroscopic behaviour has its origin in the interaction of its mi- cromechanical constituents. In addition to the coupling between hydraulic and mech- anical behaviour, a coupling between the micro (material microstructure) and macro will be made. By means of the development of a framework of computational homo- genization for hydromechanical coupling, a doublescale modelling approach is formu- lated, for which the macroscale constitutive relations are derived from the microscale by homogenization. An existing model for the modelling of hydromechanical coupling based on the distinct definition of grains and intergranular pore space [Frey, 2010] is adopted and modified to enable the application of first order computational homogenization for obtaining macroscale stress and fluid transport responses. This model is used to constitute a periodic representative elementary volume (REV) that allows the rep- resentation of the local macroscopic behaviour of the claystone. As a response to deformation loading, the behaviour of the REV represents the numerical equivalent of a constitutive relation at the macroscale. For the required consistent tangent operators, the framework of computational homogenization by static condensation [Kouznetsova et al., 2001] is extended to hy- dromechanical coupling. The theoretical developments of this extension are imple- mented in the finite element code Lagamine (Li` ege) as an independent constitutive relation. For the modelling of localization of deformation, which in classical FE meth- ods suffers from the well-known mesh dependency, the doublescale approach of hy- dromechanical coupling is combined with a local second gradient model [Collin et al., 2006] to control the internal length scale of localized deformation. By accepting the periodic boundary conditions as a regularization of the microscale deformation, the use of the multiscale model in combination with the local second gradient model can be used for modelling localization phenomena in HM-coupled settings with material softening. The modelling capacities of the approach are demonstrated by means of simula- tions of oedometer tests and biaxial compression tests. The approach is demonstrated to be a powerful way to model anisotropy in the mechanical as well as the hydraulic behaviour of the material both in the initial material state and as an effect of hy- dromechanical alterations. For the application to the modelling of Callovo-Oxfordian claystone, microstructural REVs are calibrated to geometrical characteristics of the inclusion that form the microstructure under consideration and to macroscale ex- perimental results of the mechanical behaviour. The calibrated constitutive relation is used in the simulation of gallery excavation processes. These computations give a proof of concept of the doublescale assessment of the hydromechanical behaviour of the excavation damaged zones around galleries in the context of nuclear waste disposal.

L’objectif de ce travail de thèse est le développement en technologie intégrée standard d’une structure de ligne de transmission optimisée en termes de pertes, d’encombrement, de facteur de qualité et surtout du choix du niveau de couplage aux fréquences millimétriques. Cette structure a été nommée CS-CPW (Coupled Slow-wave CoPlanar Waveguide). Dans un premier temps, la théorie ainsi que les modèles électriques des CS-CPW sont présentés. Grâce aux modèles et aux simulations électromagnétiques, des coupleurs directionnels avec plusieurs valeurs de couplage (3 dB, 10 dB, 18 dB) ont été conçus en technologie BiCMOS 55 nm. Ils présentent tous une très bonne directivité, elle est toujours supérieure à 15 dB. Un premier prototype de coupleur a été mesuré à 150 GHz. Dans un deuxième temps, des filtres à la base des lignes couplées ont été développés à 80 GHz en utilisant des lignes CS-CPW. Les résultats des simulations présentent des résultats concurrentiels avec l’état de l’art : 11% de bande passante relative et un facteur non-chargé autour de 25. Finalement, trois projets ont démarré à la base de ces lignes. Ces projets sont actuellement utilisés dans deux travaux de thèse et un stage : un RTPS à 47 GHz, un isolateur à 75 GHz et un balun à 80 GHz. / This work focuses on high-performances CS-CPW (Coupled Slow-wave CoPlanar Waveguide) transmission lines in classical CMOS integrated technologies for the millimiter-wave frequency band. First, the theory as well as the electrical models of the CS-CPW are presented. Thanks to the models and electromagnetic simulations, directional couplers with different coupling levels (3 dB, 10 dB, 18 dB) were designed in BiCMOS 55 nm technology. They have a good directivity, always better than 15 dB. A first prototype of a coupler was measured at 150 GHz presenting good agreement with the simulations. Next, coupled-line base filters were developed at 80 GHz using the CS-CPWs. Simulation present competitive results with the state-of-art: 11% of fractional bandwidth and a unload quality factor of 25. Finally, three projects started based on the CS-CPWs. The projects are currently used in two theses and one internship: a RTPS at 47 GHz, an isolator at 75 GHz and a balun at 80 GHz.