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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 51 to 60 of 683 (0.066 seconds)| 51 |
Synthetic strategies towards hydroxylated alkaloidsGibbs, Gary January 1997 (has links)
No description available.
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Studies in the dehydrogenase catalysed reduction of 2-ketocarboxylic acidsHateley, Martin John January 1998 (has links)
No description available.
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Near infrared spectroscopy technique for bioprocess monitoring and controlYeung, Ken Shu Ying January 1998 (has links)
No description available.
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A study of the use of fractionation diagrams for the study of bioprocess interactionsBird, Antony Colin January 1999 (has links)
No description available.
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Chaperonins for the assisted refolding of proteinBaker, Douglas John January 1999 (has links)
No description available.
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| 56 |
Primary biliary cirrhosis : an immunological studyPalmer, Jeremy M. January 1999 (has links)
No description available.
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Cloning and characterisation of the plant pyruvate dehydrogenase complex componentsMcGow, Donna January 2002 (has links)
No description available.
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A study of autotrophic mutants of Pseudomonas thermocarboxydovorans C2 by TN5 mutagenesisCasimiro, Mathew Craig January 1998 (has links)
No description available.
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Assessing Memory in an Aldehyde Dehydrogenase 2 Knockout Model of Alzheimer's DiseaseElharram, AHMED 28 September 2013 (has links)
The study of Alzheimer’s Disease (AD) has been hindered by the absence of animal models of late-onset/age-related AD (also termed sporadic AD) (95% of AD cases) since current transgenic mouse models exhibit pathological changes dependent on overexpression of mutant human genes linked to early-onset, familial AD (5% of cases). Oxidative stress is considered to be a causative factor in age-related AD, and we have found that aldehyde dehydrogenase 2 (Aldh2) null mice exhibit not only oxidative stress, but also display many AD-like pathologies. The current study used behavioral analysis to assess whether Aldh2-/- mice also exhibit memory and cognition deficits. Male and female wild type and Aldh2-/- mice were tested monthly beginning at three months of age, using the open field novel object recognition test (a measure of recognition memory), as well as spontaneous alternations in the Y-maze (a measure of spatial working memory). In both tasks, significant decreases in performance occurred in Aldh2-/- mice by 3.5-4 months of age, and this progressively declined over the next three months compared to wild type mice. Sex-related differences in memory impairment were not observed. These results, together with the findings that AD-like pathologies are also present, suggest that Aldh2-/- mice represent a new, oxidative stress-based model of age-related cognitive impairment and AD. This model may prove useful both for assessing AD therapeutics and for gaining better insight into the pathogenesis of AD. / Thesis (Master, Pharmacology & Toxicology) -- Queen's University, 2013-09-26 11:20:00.023
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The production and characterization of monoclonal antibodies against [beta]2[beta]2 human liver class I alcohol dehydrogenase isozyme.January 1989 (has links)
by Yu-Wai Ho. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1989. / Bibliography: leaves 122-129.
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