The purpose of my study is to investigate the treatment of individuals with a visual impairment in their work and studies based on constructs of femininity and masculinity. The method used in this study is qualitative, and it is a study based on interviews in which 7 informants with a visual impairment who have been interviewed as it is their perceived experiences that are the focus area of the study. The results that I have obtained in my study are that people with a visual impairment are treated differently by the environment and it depends on the gender to which one belongs, and in this study I have also concluded that the environmental assessments of the ability to work and learning ability of the visually impaired vary depending on the gender. This study shows how people with a visual impairment are assessed on the basis of their visual impairment, and not on the basis of their qualifications or competences in the work they have applied for or are working with. However, as these people become marginalized in the labor market, it is difficult for them to become involved in society, based on the perspective of the visually impaired, you feel that the environment assesses one's ability to work or learning ability before you even have the opportunity to show what you are able to do. This is assessed on the basis of the ignorance, fears and misunderstandings that society likes to attach to people with a visual impairment. / <p>2021-06-16</p>

Sacred texts authored in antiquity present a challenge for contemporary religious practitioners because there is always a question regarding how to interpret and apply the message today. Prominent Pentecostal theologian and disability theorist Amos Yong faces this challenge concerning the Bible as it relates to disabilities and those who have them. As I argue in this thesis, Yong succeeds in challenging the Pentecostal perceptions of disability without compromising on the over-all Pentecostal view of scripture. The Hebrew Bible, which, according to Yong, "...serves as the foundation of the Christian scriptures," contains multiple passages that portray disability in a negative light. For example, the Old Testament contains laws and regulations governing the priestly liturgical cult that place very strict guidelines on who is allowed to fulfill what duties based on one's lineage and physical condition. The Old Testament also contains passages in which the God of the Hebrews makes a covenant linking obedience with health and disobedience with sickness. The second part of the Christian scriptures (the New Testament) also includes multiple narratives that portray disability as (at the very least) an undesirable phenomenon. For example, the healing narrative and miracles attributed to Jesus and his followers are used by Pentecostals to stress the importance of physical healing. Consider also the Pentecostal understanding of the cross event. According to Pentecostal scholar Keith Warrington, the cross is used to emphasize triumph over suffering, sin, and the devil. The challenge for contemporary religious practitioners, then, is deciding how one is to interpret and apply the message of a given text today. For example, (a) how does a contemporary Pentecostal (that utilizes the Bible as a sacred text) view the phenomenon of disability and passages of scripture that marginalize the differently-able today? Furthermore, (b) how does Yong successfully arrive at non-Pentecostal convictions concerning the differently-able while maintaining his Pentecostal beliefs about scripture? In order to explain how Yong succeeds in justifying his non-Pentecostal perceptions of the differently-able one must first understand the overall Pentecostal convictions concerning scripture which inform the Pentecostal perception of disability. The authority of, and use for, the Bible as it informs the perception of disability within Pentecostalism (a variant of (a)) will be the focus of Chapter One. Chapter Two will introduce Yong's theological hermeneutic which articulates his understanding of the purpose of scripture. By examining the hermeneutical approach utilized by Yong in his earlier work Spirit-Word-Community, on biblical interpretation, one can gain a clearer picture of how he relates methods of interpretation to his perception of disability in his later work The Bible, Disability, and the Church (a variant of (b)). The final task, then, is to demonstrate how Yong successfully solves the problem of exclusion experienced by the differently-able while maintaining his Pentecostal beliefs about scripture. Chapter Three articulates Yong's hermeneutical solution to the problem of exclusion justified within the Pentecostal understanding of scripture. This is done through understanding Yong's `disability hermeneutic. This chapter explicates Yong's assertion that the way Pentecostals have misinterpreted scripture is to blame for exclusive and oppressive perceptions of disability.

Where parties are married in community of property, debts are incurred by the parties and not by the joint estate. Each spouse is liable for debt incurred by either spouse. A creditor is, therefore, entitled to claim from joint estate of both spouses (as co debtors). Such an estate includes not only the spouse's undivided interest in the joint estate but also any and all separate property that falls outside the joint estate. Once the joint estate is sequestrated, both spouses become "insolvent debtors" and consequently the property (including separate property) of both spouses is available to creditors. The lnsolvency Act, as opposed to the Matrimonial Property Act, makes no provision for the recognition or sequestration of 'separate property". Although an estate is sequestrated, it is the debtor who is insolvent. A debtor (married in community of property) who possesses "separate property" is on sequestration of the joint estate insolvent in relation to both his or her undivided interest in the joint estate as well as any "separate property". But is this correct? Ample provision is made by various statutes for the exclusion of certain property from an insolvent estate. Does this not mean that a debtor might be insolvent in relation to one estate and not insolvent in relation to the other? The estate of a partnership is, for purposes of sequestration, deemed to be a separate entity from the partners' private estates. Where the partnership fails, creditors first have recourse against the estate of the partnership where after any shortfall may be claimed from the private estates of the partners. Although the estates of partners are sequestrated simultaneously with the estate of the partnership, creditors of the partnership may not proof their claims against the estate of a partner and vice versa. Is it just and equitable that a spouse who owns separate property is treated differently from a partner who does not possess a separate estate in law from the partnership estate? A partner only has one estate - a private estate that includes his or her interest in the partnership. It is concluded that despite the judgment of the Supreme Court of Appeal in Du Plessis v Pienaar, a sense of dissatisfaction still prevails regarding the status of separate property. It is furthermore suggested that in view of the lack of provisions in the insolvency Act regarding separately owned property, the said Act be amended to provide for the specific exclusion of separate property from an insolvent joint estate. It is more advisable to provide for the exclusion of separate property from the insolvent joint estate than to provide for the simultaneous sequestration thereof. / Thesis (LL.M. (Estate Law))--North-West University, Potchefstroom Campus, 2004.

Where parties are married in community of property, debts are incurred by the parties and not by the joint estate. Each spouse is liable for debt incurred by either spouse. A creditor is, therefore, entitled to claim from joint estate of both spouses (as co debtors). Such an estate includes not only the spouse's undivided interest in the joint estate but also any and all separate property that falls outside the joint estate. Once the joint estate is sequestrated, both spouses become "insolvent debtors" and consequently the property (including separate property) of both spouses is available to creditors. The lnsolvency Act, as opposed to the Matrimonial Property Act, makes no provision for the recognition or sequestration of 'separate property". Although an estate is sequestrated, it is the debtor who is insolvent. A debtor (married in community of property) who possesses "separate property" is on sequestration of the joint estate insolvent in relation to both his or her undivided interest in the joint estate as well as any "separate property". But is this correct? Ample provision is made by various statutes for the exclusion of certain property from an insolvent estate. Does this not mean that a debtor might be insolvent in relation to one estate and not insolvent in relation to the other? The estate of a partnership is, for purposes of sequestration, deemed to be a separate entity from the partners' private estates. Where the partnership fails, creditors first have recourse against the estate of the partnership where after any shortfall may be claimed from the private estates of the partners. Although the estates of partners are sequestrated simultaneously with the estate of the partnership, creditors of the partnership may not proof their claims against the estate of a partner and vice versa. Is it just and equitable that a spouse who owns separate property is treated differently from a partner who does not possess a separate estate in law from the partnership estate? A partner only has one estate - a private estate that includes his or her interest in the partnership. It is concluded that despite the judgment of the Supreme Court of Appeal in Du Plessis v Pienaar, a sense of dissatisfaction still prevails regarding the status of separate property. It is furthermore suggested that in view of the lack of provisions in the insolvency Act regarding separately owned property, the said Act be amended to provide for the specific exclusion of separate property from an insolvent joint estate. It is more advisable to provide for the exclusion of separate property from the insolvent joint estate than to provide for the simultaneous sequestration thereof. / Thesis (LL.M. (Estate Law))--North-West University, Potchefstroom Campus, 2004.

This thesis examines contribution of the Vodafone foundation program Year diffe- rently. More precisely it examines changes caused by the program from the point of view of participants and non-profit organizations and the programs long time bene- fit. The thesis focuses on organizations development by management branch, sociological branch and on diversity of organizations. It also focuses on the work of the manager and the impact of this work on his/hers mental condition. Practical part of the thesis analyzes year 2014 by using content analysis, semantic analysis and interviews. Possible use of determinated principles of Year differently for deve- lopment of civil society organizations and candidates is based on the research.

This study reflects on how the experiences of differently abled persons can inform career development. This will assist in the identification of support needed by differently abled persons and will assist in informing career development programs and policies. This study is aimed at preparing differently abled persons to make appropriate career choices, and also providing motivation to pursue further education and enhancing employability for social justice. Four participants were selected with the objective of investigating the types of support needed for effective career development of differently abled persons. A qualitative case study was used for the purpose of obtaining in-depth insight and understanding whilst data was collected through face-to-face semi-structured interviews and an inductive thematic analysis was used to analyse the data. Participants indicated that family, teachers and lecturers assisted them on their career development journey. The findings highlighted that educational institutions can be a valuable resource for the career development of differently abled persons and that participants’ personal attributes also played a role. Results from the study shed light on society in general as differently abled participants indicated that people and institutions are often not very accommodating and are unaware of the unique challenges they face. It is hoped that the findings of this study will assist in informing career development programs and policies. This will mean that differently abled persons are more prepared to make appropriate career choices. This will also provide them with motivation to pursue further education and especially enhance the employability of differently abled persons for social justice. / Dissertation (MEd)--University of Pretoria, 2019. / Educational Psychology / MEd / Unrestricted

La méthylation de l'ADN génomique est l'un des principaux mécanismes épigénétiques qui conduisent à des changements stables et héréditaires de l'expression des gènes sans que cela s’accompagne de la modification de la séquence d'ADN sous-jacente. Elle fait référence à l'addition d'un groupement méthyl sur le carbone 5 des cytosines (5meC). Ces dernières années, l’étude des mécanismes régulant la mise en place et le maintien de de cette méthylation est devenu un thème de recherche importante, en raison de son rôle essentiel dans la régulation du fonctionnement du génome des plantes et des mammifères. La distribution des 5meC sur l’ensemble du génome d’un organisme, encore appelé méthylome, peut être déterminée par différentes méthodes dont le séquençage de l’ADN génomique après traitement au bisulfite de sodium (WGBS ou méthyl C séq). Chez les végétaux, la méthylation de l’ADN peut se produire dans tous les contextes de séquence incluant les motifs symétriques CG et CHG et le contexte dissymétrique CHH (H pouvant être A, T ou C). En fonction du contexte de séquence, la méthylation des cytosines est mise en place et maintenue par trois types différents d'ADN méthyltransférase. [ ] Chez la plante-modèle Arabidopsis, la déméthylation active de l'ADN joue un rôle essentiel dans l'empreinte maternelle et la déméthylation l’ADN génomique lors du développement de l’albumen, mais elles ne semblent pas jouer de rôle essentiel pendant le développement de la plante chez cette espèce. La méthylation de l’ADN génomique peut aussi être perdue après la réplication de l’ADN, lorsque les mécanismes devant assurer son maintien ne sont pas actifs. On parle alors de déméthylation passive de l’ADN génomique. [ ] En conclusion, les observations présentées dans ce travail fournissent un cadre de travail permettant d’analyser les mécanismes moléculaires responsables de la déméthylation de l'ADN se produisant pendant la maturation des fruits de tomate. Ici, nous présentons une analyse complète des conséquences d’une réduction de l’expression du gène de SlDML2 sur le trancriptome et le métabolome des fruits, tout au long de leur développement. La corrélation entre les profils d’expression de gènes réalisées lors de ce travail ( variété WVA106) et les changements de la distribution de la méthylation de l’ADN telles que décrites chez la variété Ailsa craig montre qu’en plus d'un rôle général dans la régulation des gènes directement impliqués dans plusieurs voies métaboliques, plusieurs gènes codant pour des facteurs de transcription ainsi que des régulateurs épigénétiques sont également susceptibles d'être directement contrôlés par la méthylation de leur région promotrice. Cependant, nous ne pouvions pas établir une relation stricte entre la diminution de la méthylation de l'ADN et l'induction de l'expression des gènes, car de nombreux gènes présentant une diminution du niveau de méthylation de l'ADN dans leur région promotrice pendant la maturation des fruits sauvages correspondent à des gènes normalement réprimés. Ceci suggère que la méthylation active de l'ADN serait nécessaire à leur répression pendant le processus de maturation. Ainsi la relation entre la déméthylation de l'ADN et l'expression des gènes pourrait être plus complexe et ne se limiterait pas à la simple hypothèse de départ de ce travail: la déméthylation de l'ADN est nécessaire à l'expression de gènes induits au cours de la maturation. La déméthylation active de l'ADN pourrait également être nécessaire à la répression de gènes exprimés uniquement lors des phases précoces du développement des fruits et réprimés lors du murissement. / DNA methylation is one of the epigenetic mechanisms that lead to stable and heritable changes in gene expression without alteration on DNA sequence. DNA methylation refers to the addition of a methyl group to the fifth position of the cytosine ring. In recent years, DNA methylation is becoming more and more widely studied, because of its importance in mammals and plants. Methylated cytosines distribution can be determined across the genome at single-nucleotide resolution, that is methylome, using whole genome bisulfite-sequencing (BS-seq) approaches. [ ] Solanum lycopersicum (tomato) is an important agronomic crop and the main model to study the development and ripening process of climacteric fleshy fruit. Recent studies have now shown that the development and ripening of fleshy fruits relies on the establishment and maintenance of differential transcription patterns and complex regulatory pathways that involve both genetic and hormonal controls are operating at these developmental phases. However, it appears that a full understanding of fruit development and ripening will not be achieved based only on genetic models as suggested by recent studies, which showing an important decrease in global methylation level and demethylation at specific promoters during fruit ripening. [ ] In conclusion, the observations presented in this work provide a framework for analysis of the molecular mechanism of DNA demethylation during fruit ripening of tomato. Here, we provide a comprehensive analysis of the knock down SlDML2 on the trancriptome, metaoblom and DNA methylation in the promoter analysis. The large transcriptional reprogramming that occured in mutant during fruit ripeing was correlated alterations in DNA methylation. Here we highlight the central role of active DNA demethylation during tomato fruit ripening. In addition to a general role in the regulation of genes directly involved in several metabolic pathways, we also found that several transcription factors as well as epigenetic regulators are also likely under direct methylation control. However, we could not establish a district relationship between DNA reduction of DNA methylation and induction of gene expression, as not all DEGs containing a type-a DMRs (decreased DNA methylation during fruit ripening) do not correspond to genes normally induced in WT and repressed in transgenic plants. Some were corresponding to an opposite situation and in a few cases more complex methylation pattern (several DMRs) were also found. Indeed these conclusions are based on methylation analysis obtained in another variety. They might however reflect the situation of WVA106 fruits, although some variations are expectable when the methylome of DML RNAi fruits will be analyzed. Hence the relationship between DNA demethylation and gene expression might be more complex than expected, and not limited to the starting hypothesis of this work: DNA demethylation is an absolute requirement for the expression of critical ripening induced genes. This is indeed clearly in this study, but the analysis presented here also suggest that DNA demethylation might also be necessary for the repression of several genes as well. In addition, from the rencent study in Arabidopsis, ROS1 were found preferentially targets transposable elements (TEs) which are closer to protein coding genes and intergenic regions, which suggesting that ROS1 may prevent DNA methylation spreading from TEs to nearby genes. While in tomato, as our analysis, we found the methylation level of promoter of a number of genes was altered during fruit ripening, therefore, through methylome analysis, we will also get the preference of DNA methylation on TE, this analysis will give us idea that demethylation in fleshy fruit may has other distinct function as it is in Arabidopsis.

The work deals with finding the position of the gallery / museum education in art education for children with special educational needs. The first part is devoted to the theoretical background of the topic, explains the basic terms (visual literacy, gallery / museum education). A substantial part is devoted to research in the field of the gallery / museum education in art education for children with special educational needs. The survey has a qualitative charakter and trying to describe possibilities and limits of children with disabilities in the gallery programs. At the same time provides essential findings on the form of art education in concrete school achieved through an analysis of the relevant curriculum documents and interviews with teachers. For the processing of the acquired data are used qualitative research methods. The work aims to identify a design of concrete the relevant curriculum document. Art of the work takes the form of educational materials.

The goal of my study is to develop a mobile application to enable all visitors, including blind and low-vision visitors, to autonomously gather and share information about interpretations of art and to have a fully independent museum-going experience. With an application, blind visitors have more access to opportunities and tools in the museum, which empowers their museum experience. My study used a qualitative, mixed-methods approach to research how blind and low vision museum visitors might increase their independence in the museum space and discover ways to equalize their access without relying on museum educators. In carrying out my study, I conducted interviews and collected data based on observations and transcribed and analyzed them using a grounded theory approach. I used Freire's theory of pedagogy of the oppressed and hooks' theory of education as the practice of freedom to frame my study.

There is limited anthropological research on inclusive play and universally designed playgrounds and this study aims to make some contribution in this field. This was a qualitative research study guided by anthropological theory and methods, conducted for For the Love of the Lake (FTLOTL) Foundation. FTLOTL is a non-profit organization located in Dallas, Texas, dedicated to White Rock Lake Park's maintenance. In 2014, FTLOTL became of the view that the park's current playgrounds lacked accessibility for differently-abled children. Therefore, FTLOTL decided to undertake a renovation project of Flag Pole Hill playground to incorporate inclusiveness and diversity in the playground design. The overarching objective of this exploratory, ethnographic needs assessment was to provide insights for an inclusive playground using universal design for families with special needs children. Fourteen parents, each with at least one child having physical, social, or intellectual disabilities in the Dallas/Fort Worth (DFW) Texas metroplex were interviewed. The interviews were semi structured, each lasting for about an hour and were digitally recorded. Later these audio recordings were transcribed verbatim and then coded using Dedoose. The coded data was synthesized into coherent themes and sub-themes and finally organized into formal research findings. Observations were made of existing universally designed as well as typical playgrounds in this region. All parents interviewed supported the playground initiative and gave suggestions for physical accessibility along with social inclusion. They expressed their frustrations and apprehensions about the usability of current playgrounds. They also shared their preferences for facilities, features, and equipment to support their children's physical and social needs as well as their own. There was a unanimous agreement that a universally designed playground would have recreational, therapeutic and emotional benefits for participants and would improve the quality of their family lives and build a more closely-knit community.